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At least 19 recordsLinked to original sources
PubMed2004

Influence of inter-pregnancy interval on preterm delivery.

The influence of pregnancy spacing on preterm delivery (<37 weeks gestation) was examined in a group of mothers attending three Maternal and Child Health centres in three different districts in the city of Alexandria, Egypt between October 2001 and July 2002. All pregnant mothers attending the centres were interviewed or had their medical records reviewed. They were followed up until delivery and were questioned about current and past obstetric history and their medical history; their haemoglobin level was measured. The inter-pregnancy interval was calculated as the number of months between the delivery date of the women's last previous live infant and the date of the last menstrual period before the current pregnancy. There were 1202 pregnant women eligible for inclusion. The inter-pregnancy intervals were divided into five categories: <12, 12-36, 37-48, 49-60 and >60 months. We calculated the rates of preterm deliveries for each inter-pregnancy interval. Unadjusted odds ratios were estimated and stepwise logistic regression analysis was then used to adjust for all confounding factors. The rate of preterm delivery was 9.4%, and the lowest risk occurred in women who had an inter-pregnancy interval >60 months; 7.3% of those women gave birth to preterm infants. The rate of preterm delivery increased with increasing inter-pregnancy interval until 49-60 months; however, the association between inter-pregnancy interval and preterm delivery was not statistically significant whether using the crude or adjusted odds ratios.

Adult↗
PubMed1978

The interactive effects of induced abortion, inter-pregnancy interval and contraceptive use on subsequent pregnancy outcome.

Prior induced abortion and outcome of the next pregnancy are investigated, allowing for two intervening and potentially confounding variables: 1) length of interval between the termination of the first pregnancy and the conception of the next (inter-pregnancy interval) and 2) the utilization of contraception during this interval. Results show that non-contracepting (susceptibility) intervals which immediately precede a subsequent pregnancy are significantly shorter following an induced abortion than those following a spontaneous abortion or delivery. A life table analysis of all susceptibility intervals confirmed this finding. To investigate outcome of subsequent pregnancy as influenced by preceding pregnancy outcome, inter-pregnancy interval and contraceptive use in the interval, a categorical linear model has been developed. Among non-contraceptors, the model indicates no differences in proportions of succeeding adverse outcomes (spontaneous abortion or low birth weight) regardless of inter-pregnancy interval and whether or not the preceding pregnancy had been terminated by an induced abortion. For the contraceptive users, however, proportions of adverse outcomes increased with length of inter-pregnancy interval, and, within each interval category, proportion of adverse outcomes was higher when the preceding pregnancy had terminated in an induced abortion.

Abortion, Induced↗
PubMed1976

Short pregnancy interval, low birthweight, and the sudden infant death syndrome.

Pregnancy intervals were calculated for 54,369 later-born singletons delivered during 1969 in the State of North Carolina. Subsequent infant deaths among this cohort were categorized into probable sudden infant death syndrome (SIDSp), other postneonatal home deaths, all postneonatal hospital deaths, all neonatal deaths, and all deaths due to congenital malformations. Each death was matched with a control drawn from the population of infants surviving the first year of life. The matching variables were maternal age, race, mother's education and number of previous live births. All categories of death showed higher proportions of short intervals among cases than controls. Comparing the interval distributions by means of the X2 test for linearity produced significant results for only SIDSp and neonatal deaths. It was concluded, however, that short-pregnancy interval probably has a similar effect on the risk of death from all five cause of death groups. The introduction of birthweight as a fifth matching variable left no significant differences in the distributions of pregnancy intervals between cases and controls. This was interpreted as evidence that short pregnancy interval exerts its influence on risk of death in infancy through its effect on birthweight. The estimated reduction in prematurity and infant mortality that might result from the elimination of short pregnancy intervals was 5% and 6%, respectively.

Adult↗
PubMed1989

The association of inter-pregnancy interval with small for gestational age births.

The association between small for gestational age (SGA) birth at term and inter-pregnancy interval was examined in a hospital cohort of 4489 multiparous women. The greatest risk of SGA birth was found in women with the shortest inter-pregnancy intervals. Even after adjusting for multiple confounding factors, women whose inter-pregnancy interval was 18 or fewer months (over one-third of women in the cohort) remained at twice the risk of giving birth to a term SGA infant when compared with women whose inter-pregnancy interval was 24-36 months. In a logistic regression analysis examining the occurrence of SGA birth in women with inter-pregnancy intervals of 36 months or less, a strong linear association was noted between these two factors. The association of term SGA birth with short inter-pregnancy interval could result from one or more physiologic factors that might act to limit fetal growth. In that case, short inter-pregnancy interval would represent a potentially preventable cause of SGA birth.

Birth Intervals↗
PubMed1993

Pregnancy intervals: their determinants and foetal outcome at the KCMC, Moshi, Tanzania.

A total of 566 multigravidae who delivered at the Kilimanjaro Christian Medical Centre (KCMC), Moshi, between 15th May and 30th July, 1989, were interviewed to determine the pregnancy intervals, their determinants as well as foetal outcome. 62.1% of the study group had pregnancy intervals longer than 2 years. The factors which appeared to influence pregnancy interval in this study included maternal age, period of breastfeeding, postpartum amenorrhoea, postpartum coital abstinence, contraception and outcome of the preceding pregnancy. Other factors such as maternal education, occupation, marital status, pregnancy order, and religion, did not appear to have any effect on the pregnancy intervals. The pregnancy interval did not seem to affect the outcome of the index pregnancy. It is recommended that those factors with a positive impact on pregnancy interval be promoted as widely as possible in Tanzania, so as to contribute toward the control of population growth, as well as the overall maternal and child health, and national economy.

Adolescent↗
PubMedDate not supplied

Malaria specific-IgG, inter-pregnancy intervals, birth weights and body mass index in cases of asymptomatic malaria parasitaemia.

BACKGROUND & OBJECTIVES: Considerations of both inter-pregnancy intervals and malaria parasitaemia may help in understanding some aspects of susceptibility and pregnancy outcomes in malaria endemic areas. METHODS: Pregnant women with asymptomatic malaria parasitaemia were recruited and divided into groups based on their inter-pregnancy intervals and malaria specific-IgG, body mass index, and birth weights were studied in the groups. RESULTS: The results showed that the P. falciparum specific-IgG concentration (f=3.52, p<0.02), malaria parasites density (f=6.44, p<0.001) and birth weights (f=7.36, p<0.001) were significantly different amongst the groups with varying inter-pregnancy intervals. In addition, different levels of associations between variables such as 'inter-pregnancy intervals vs P. falciparum specific-IgG concentration' (r = 0.23, p<0.05); 'malaria parasites density vs birth weight' (r = -0.84, p < 0.01) was observed. INTERPRETATIONS & CONCLUSION: This study suggests that inter-pregnancy intervals could be one of the factors influencing dynamic serum concentrations of P. falciparum specific-IgG while malaria parasitaemia could be one of the factors affecting birth weights. Hence, observance of inter-pregnancy intervals has its own implications in malaria endemic areas.

Analysis of Variance↗
PubMed1994

Relevance of the miscarriage-new pregnancy interval.

There is a wide divergence of opinion concerning the interval a woman should wait after a miscarriage before attempting a new pregnancy ("pregnancy interval"). Many authors recommend waiting 3-4 months in order to reduce the risk of another miscarriage [3, 6, 17, 21]. This retrospective study investigated whether a longer pregnancy interval lowers the risk of repeat miscarriage (R-risk) and/or prematurity. The association between parity and R-risk was also analyzed. Results showed that there are no proven reasons to recommend a waiting period between a miscarriage and a subsequent pregnancy, because the R-risk was around 20% irrespective of interval duration. Prematurity too is not influenced by a waiting period after miscarriage. There was, however, an association between parity and R-risk and risk of prematurity: nulliparae were more likely to have a repeat miscarriage (p < 0.05) or a preterm delivery in the next pregnancy (p < 0.05) than women who had already given birth to a child.

Abortion, Spontaneous↗
PubMed2000

The evaluation of determinants of early postpartum low mood: the importance of parity and inter-pregnancy interval.

OBJECTIVES: The aim of this study is to determine the extent of early postpartum low mood and possible relevant variables in our population. STUDY DESIGN: Depressive symptoms were examined in a sample of 85 women in the first week of postpartum period using Beck Depression Inventory (BDI). The relevant sociodemographic variables were tested by multiple logistic regression analysis. RESULTS: The rate of postpartum low mood (BDI score >10) was found 35.2%. High parity, long marriage period and low education level were all significantly associated with low mood in the postpartum first week. When logistic regression analysis was used to eliminate confounding effect of the parameters; grandmultiparity, short inter-pregnancy interval and low educational level were found to have important effect on postpartum low mood. CONCLUSION: Pregnant women with risk factors for postpartum low mood such as grandmultiparity, short inter-pregnancy interval and low educational level should be identified early during antenatal period. Educational and social support should be given to those in such a risk. We believe that effective family planning programs and improvement of women's educational level are important preventive factors for postpartum low mood and subsequently developing depression.

Adult↗
PubMed2004

Pregnancy interval and delivery outcome among HIV-seropositive and HIV-seronegative women in Kisumu, Kenya.

OBJECTIVE: A short pregnancy interval (PI) has been associated with increased child mortality, but mechanisms are unclear. We studied factors associated with PI and the effect of PI on birthweight and haemoglobin. METHODS: Information was analysed from 2218 multigravidae who were recruited at the prenatal clinic (1758) or in the labour ward (460) of the Provincial Hospital in Kisumu between June 1996 and July 2000 for a study to assess the interaction between placental malaria and vertical HIV transmission. RESULTS: The HIV prevalence was 28.9%. HIV seropositivity, older age, being unmarried, and <8 years of education were associated with a prolonged PI; among all women, a stillbirth, abortion, or death of a liveborn child as outcome of the previous pregnancy, and death of a child other than the last born among HIV-seronegative women, were associated with a shortened PI. No significant effect of short PI (an interval <24 months) on low birth weight (LBW), prematurity, small-for-gestational-age infants or maternal anaemia was evident. An abortion, stillbirth, or death of a liveborn child as outcome of the previous pregnancy was associated at the present delivery with LBW among HIV-seronegative women [adjusted odds ratio (AOR) 3.33, 95% confidence interval (CI) 1.63-6.81], and a low haemoglobin (<11 g/dl) among HIV-seropositive women (AOR 2.01, 95% CI 1.05-4.03 in the third trimester). CONCLUSION: Public health efforts to ensure 'adequate' birth spacing may run contrary to family planning decisions to replace a deceased child and may be spent on prenatal issues like prevention of anaemia, and vertical HIV transmission.

Abortion, Spontaneous↗
PubMed1993

Changes in the determinants of fertility in Korea: analyses of pregnancy intervals and outcomes.

Korea completed the whole process of what is called the demographic transition to a low fertility and mortality level with the successful implementation of the national family planning program in 1962, and this has been accompanied by rapid socioeconomic development. Most of the fertility decline was due to a rising age at marriage and to lower marital fertility. The national family planning program, combined with the widespread practice of induced abortion, has placed an important role in reducing marital fertility, particularly among older women. This paper aims, therefore, to examine the determinants of fertility and their changes over time in an effort to suggest future population policy directions for Korea. The analysis is divided into 2 parts-estimation of pregnancy intervals by applying the proportional hazards model, and estimation of the determinants of fertility by adopting the logistic regression model to find out whether a pregnancy terminates in a live birth or in an abortion. In both analyses, the sex was included as the main explanatory variable. A woman's education has been shown to have a significant effect on delaying the timing or on the wife's age at first pregnancy, but its effect on the pace of subsequent pregnancies is much smaller and often positive. On the other hand, the woman's education has a consistently positive effect on the probability of a pregnancy ending in an abortion although the effect shows a steady decline over time. Form first parity, the sex composition of previous children stands out consistently as the most important factor in deciding both the pace of pregnancy and its outcome. The pregnancy risks of the women with sons are reduced by almost 50% at the second and third parities. The probability of a pregnancy ending in an abortion also increases substantially when parents already have a son. The decline of the desired family size but the sustained strong son preference has made the sex of children a more important factor in the determination of Korean fertility. The woman's education, on the other hand, has become a less important factor.

Abortion, Induced↗
PubMed1988

Abortion risk and pregnancy interval.

In a group of 187 women, the result of the next pregnancy following a spontaneous first-trimester abortion was studied, in relation to the interval between the two pregnancies. Conception within 3 months of the abortion gave no greater risk for another abortion than did conception after a longer interval (9/56 = 16% vs. 24/131 = 18%).

Abortion, Spontaneous↗
PubMed1983

Infant and child survival and contraceptive use in the closed pregnancy interval.

While previous studies have examined the relationship between child survival and contraceptive use, they have not considered the impact of the sequence of child mortality on the practice of family planning. The present paper addresses this issue by considering how the birth order of nonsurviving outcomes affects the decision to contracept in the subsequent interval, using data collected from over 10,000 women at the time of hospital delivery. Results indicate that, even when gravidity and the total number of surviving children are held constant, the outcome of the penultimate pregnancy is highly associated with interval contraception.

Birth Intervals↗
PubMed2002

[Short pregnancy interval and reproductive disorders].

The cause of the 'borderline personality disorder' of Vincent van Gogh has been discussed in social-psychiatric terms related to so-called 'substitute children', born after the loss of a previous child. A biological-organic genesis, i.e. the very short birth interval of precisely one year between Van Gogh and his older brother appears to be a more plausible explanation. Personality disorders, which are part of the spectrum of schizophrenic disorders, seem to belong to the very broad 'continuum of reproductive casualties' and to be caused by non-optimal maturation of the oocyte during the postpartum restoration of the ovulatory pattern. This continuum occurs during each of the transitional stages of reproductive life in which the maturation of the oocyte is constrained and consists of chromosomal aberrations, (discordant) monozygotic twins, early and late foetal death, preterm births, intrauterine growth retardation, congenital abnormalities, perinatal and neonatal mortality, cot death, growth and mental defects, and finally, chronic or 'constitutional' diseases. Non-optimal maturation of the oocyte appears to be a risk factor for the reproductive casualties stated.

Birth Intervals↗
PubMed1979

Perinatal period and pregnancy: intervals of high risk for chemical carcinogens.

Experiments in rodents indicate that during the post-embryonic period of prenatal development, the fetus is more sensitive than the adult to certain carcinogens, by several decimal orders of magnitude. Most such agents are direct-acting and independent of metabolism. To other substances, often those which require enzyme-mediated metabolic conversion to a chemically reactive derivative in order to effect carcinogenesis, the fetus may be less vulnerable than the adult. The neonate is also more susceptible than adults to some carcinogens, and may be more susceptible than the fetus to certain agents. Both rodent and primate studies indicate that gravid females are also at elevated risk for carcinogenesis, in part because of the presence in the placenta of trophoblastic tissue which may become malignant. The contributions of rapid growth rate, changing metabolic competence, and tissue differentiation to elevated perinatal susceptibility to carcinogens in rodents and primates are discussed, together with the implications of these findings for human beings subjected to industrial or environmental exposures to such chemicals.

Adult↗
PubMed1996

[Birth intervals and birth of low weight infants in Benin].

Low birthweight is a public health problem in Benin but its etiology remains unclear. Studies in industrial countries suggest several risk factors including the interval between pregnancies or child spacing. The purpose of this cohort study was to assess the relationship between pregnancy interval and low birthweight in Benin. Data were collected from a total of 2,862 multiparous pregnant women randomly recruited in 1991 at the time of their first prenatal care visit to maternity units in Cotonou, Benin. Sociodemographic information and obstetrical history were obtained by interviewing the mother and reviewing delivery records. About 15% of the women recruited delivered low birthweight children. The relative risks of preterm birthweight and intrauterine growth retardation was calculated in function of three pregnancy intervals: less than 12 months, 12 to 23 months, and 24 to 34 months. It was 1.31 (1.00-1.75), 1.00 (0.70-1.02)) and 0.77 (0.60-0.87) respectively for preterm birthweight and 1.27 (1.03-1.64), 1.17 (0.79-1.39) and 0.79 5 (0.57-0.87) respectively for intrauterine growth retardation. Logistic regression analysis taking into account sociodemographic factors and previous obstetrical history did not show a significant correlation between pregnancy interval and preterm low birthweight or between pregnancy interval and intrauterine growth retardation. Maternal nutritional status, maternal age, number of previous births, and education level were correlated with low birthweight.

Adult↗
PubMed2006

Late pre-term (32 - 36 weeks) birth in a North London hospital.

Most of the complications of pre-term delivery arise in the 1 - 2% of births before 32 weeks' gestation. However, late pre-term birth (32 - 36 weeks' gestation) is still worrying for the mother and clinician. In a retrospective study that compared the management and outcome of 103 singleton pregnancies delivered between 32 and 36 weeks' of gestation with 103 age-matched controls that delivered at term, a short inter-pregnancy interval, early pregnancy bleeding, pre-labour spontaneous rupture of membranes, a history of pre-term delivery and Asian race or single marital status were found to be significant factors. The groups did not differ in parity, BMI, smoking status or history of miscarriages and terminations. Following a logistic regression analysis, the following emerged as risk factors for late pre-term delivery; a history of previous pre-term delivery (OR = 7.2; 95% CI 1.6 - 33.2), a short (<12 months) inter-pregnancy interval (OR = 4.1; 95% CI 2.2 - 7.5), early pregnancy bleeding (OR = 7.6; 95% CI 1.3 - 38.3) and pre-labour spontaneous rupture of membranes (OR = 13.3, 95% CI 3.1 - 55.2).

Adult↗