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At least 19 recordsLinked to original sources

Factors associated with pneumothorax and pneumothorax requiring treatment after percutaneous lung biopsy in 443 consecutive patients.

PURPOSE: To describe patient- and procedure-related factors associated with post-biopsy pneumothorax and those that require intervention. MATERIALS AND METHODS: Patient and procedure data from all lung biopsies performed at a single center between January 2000 and July 2001 were recorded prospectively. Data included patient demographics, lesion size, lesion depth from skin, needle size, number of passes, patient position during biopsy, imaging method used (computed tomography/fluoroscopy), if sedation was used, occurrence of pneumothorax and whether the pneumothorax required treatment. Patient charts were retrospectively reviewed to determine smoking history, as well as previous ipsilateral chest surgery or radiation therapy. Univariate and multivariate analysis was performed, and P <.05 was considered significant. RESULTS: Four-hundred fifty-three biopsies were performed on 443 patients. One-hundred six patients (23.4%) had post-biopsy pneumothorax and 31 patients (6.8% overall, 29.2% of pneumothorax group) required intervention. By univariate analysis, increased patient age, smaller lesion size, increased depth from skin, supine position, and no history of surgery were significant predictors of biopsy-related pneumothorax. However, only increased patient age, supine position, no history of ipsilateral surgery, and history of smoking were associated with pneumothorax that required intervention. By multivariate analysis, increased patient age, smaller lesion size, and no history of surgery predicted pneumothorax; supine position, history of smoking, and no history of ipsilateral surgery predicted which patients with pneumothorax would require treatment. CONCLUSION: Independent risk factors for pneumothorax include increased patient age, smaller lesion size, and no history of surgery. Previous surgery and prone positioning during biopsy appear to provide a "protective effect" against clinically significant post-biopsy pneumothorax.

Adult↗

Rabbit pneumothorax. Feasibility of an animal model to simulate neonatal pneumothorax.

RATIONALE AND OBJECTIVES: The feasibility of developing an animal model to simulate radiographic features of neonatal pneumothorax was investigated, and supine computed radiography (CR) and film-screen radiography (FS) images were compared. METHODS: 5-Fr pigtail catheters were inserted into the right pleural space of three New Zealand white rabbits. Two CR and two FS supine images were obtained using identical technique. After serial 4-mL injections of air, one CR and one FS supine image were obtained. The images were masked and randomized, and four radiologists reviewed the images for typical signs of pneumothorax. Chest computed tomography (CT) was performed before the injection of any air and after completion of the study. RESULTS: At zero-mL air volume, radiologists did not perceive a pneumothorax. As the air volume increased, the number of signs of a pneumothorax increased; there was no significant difference between CR and FS in the number of signs of pneumothorax detected at any volume. Chest CT confirmed that there was no unexplained air leak. The volume of air injected correlated with the calculated volume from the CT. CONCLUSIONS: This induced, volume-controlled, animal model simulated the supine radiographic features of neonatal pneumothorax.

Animals↗

Accidentally created tension pneumothorax in patient with primary spontaneous pneumothorax--confirmation of the experimental studies, putting into question the classical explanation.

BACKGROUND: The widespread explanation of patophysiology of tension pneumothorax is that compression to the mediastinum by the progressively accumulating intrapleural air causes torsion at the atrio-caval junction, impaired filling of the right heart and circulatory arrest as potentially life-threatening complication. Some experimental studies on animals put into question such an explanation, suggesting that respiratory arrest due to hypoxia of the respiratory center, not a circulatory arrest, represents dominant life threatening feature. CASE REPORT: we present a patient with spontaneous pneumothorax in whom tension pneumothorax occurred accidentally, i.e., in whom air was insufflated under great pressure from the aspirating system into the pleural cavity, immediately after insertion of a chest tube. As the situation was recognized immediately, urgent reanimation was undertaken--endotracheal intubation, ventilation through the balloon, reconnection of the chest tube to another aspirating system. Lung reexpansion was achieved and the patient was discharged after an uneventful course. In this patient, it was possible to register the sequence of events before, during and after the incident. Dominant clinical finding during resuscitation of this apnoic, cyanotic and unconscious patient was respiratory arrest in presence of evident maintenance of peripheral circulation, that supports results of experimental studies. Dominant findings in experiments with creation of tension pneumothorax was that, although pressures rose throughout the right side of the circulation, no developing pressure gradient was found on this side of the circulation; furthermore, respiratory arrest preceded cardiac arrest in these animals. Hypoxia of the respiratory center, caused by the increasing portion of pulmonary blood flow being shunted through nonventilated or hypoventilated lung, was suggested as primary cause of death of experimental animals. The same factor seems to be a cause of respiratory arrest in our patient. CONCLUSION: respiratory arrest, preceding circulatory arrest, seems to be the principal life threatening condition in patients with progressive tension pneumothorax.

Animals↗

Treatment of postbiopsy pneumothorax with a self-contained pneumothorax treatment device.

PURPOSE: To evaluate the usefulness of a self-contained pneumothorax treatment device, in which a catheter and a one-way valve compose a single unit, in cases of postbiopsy pneumothorax. MATERIALS AND METHODS: Twenty-one patients underwent placement of the device to drain a postbiopsy pneumothorax. Treatment was considered successful when no therapy other than the device was needed. RESULTS: Treatment was successful in 16 (76%) of the 21 patients. Causes of treatment failure were dislodgment of the device (n = 3), malfunction of the device (n = 1), and a persistent air leak that led to pneumothorax recurrence after removal of the device (n = 1). Eight patients (38%) experienced problems after insertion of the device: The device dislodged in seven patients and malfunctioned in one patient. These problems led to treatment failure in four patients (see above). In the remaining four, further treatment after device dislodgment was not required. CONCLUSION: Treatment with the self-contained pneumothorax treatment device shows promise. Modifications to the device may alleviate technical problems and insertion difficulties.

Aged↗

Case of simultaneous bilateral spontaneous pneumothorax developed into tension pneumothorax.

Spontaneous pneumothorax is a relatively common disease in the clinical practice setting and is generally recognized to occurs most often in slender young men. However, spontaneous pneumothorax that occurs bilaterally and simultaneously and progresses to tension pneumothorax has rarely been documented. Although spontaneous pneumothorax can be diagnosed based on the patient's medical history or information from ambulance personnel, it should be remembered that there are some rare cases of bilateral tension pneumothorax. Prompt and appropriate diagnosis and treatment are necessary for patients with such conditions, which may can be life-threatening.

Drainage↗

Pleura in pneumothorax. Comparison of patients with cystic fibrosis and idiopathic spontaneous pneumothorax.

We studied pleura from patients with cystic fibrosis (CF) in order to define abnormalities that predispose to pneumothorax or are unique to CF. We compared the histology of CF pleura with that of young non-CF adults with "idiopathic" pneumothorax. Both CF and non-CF patients with pneumothorax showed distorted elastic fibers in areas of pleural fibrosis, adhesions, or air "cysts." Following pneumothorax, chronic inflammation, granulation tissue, fibrosis, mesothelial hyperplasia, and reactive eosinophilic pleuritis were also common. Although CF pleura appeared more intensely inflamed, only myxoid connective tissue and vascular proliferation were significantly more frequent in CF. Columnar, vacuolated mesothelial cells (Dunnill lesion) were focally observed only in patients with CF. We conclude that extensive degenerative pleural changes may predispose to pneumothorax in CF and represent a nonspecific response to chronic inflammation.

Adolescent↗

[Noisy pneumothorax. Clicking pneumothorax mimicking pericarditis].

A clicking, crackling, or crunching sound over the cardiac apex, sometimes followed or accompanied by left-sided chest pain, is usually thought to be caused by pericarditis. It is frequently ignored that these symptoms can be due to a small left-sided pneumothorax, called noisy pneumothorax. The pneumothorax can be visualized on X-ray taken in full expiration. Noisy pneumothorax can be followed by various electrocardiographic changes, thus simulating myocardial infarction and other serious heart diseases. Therefore, it is important to have this differential diagnosis in mind as a possibility when healthy, young people are admitted to the hospital with heart symptoms. Two cases of noisy pneumothorax simulating pericarditis are described.

Adult↗

Colonoscopy-associated pneumothorax: a case of tension pneumothorax and review of the literature.

A 64-year-old woman presented with severe abdominal pain and was found to have a large fecolith in the sigmoid colon with resulting bowel obstruction. During a therapeutic colonoscopy, she developed severe shortness of breath and hypoxia, and was found to have a tension pneumothorax. We review the potential mechanisms by which pneumothorax may occur following colonoscopy. In addition, the eight previously published cases are reviewed. Pneumothorax, with or without pneumomediastinum, can occur through a variety of mechanisms following colonoscopy. Although rarely reported, this may represent an underappreciated complication and should be fully investigated in the appropriate setting. Colonoscopy, an exceedingly common procedure, will continue to increase with the aging population. As a result, tension pneumothorax can have a profound effect on the patient outcome and therefore physicians, both gastroenterologists and pulmonologists, should be aware of all the potential problems with this procedure.

Colonoscopy↗

Catheter aspiration for simple pneumothorax (CASP) in the outpatient management of simple traumatic pneumothorax.

Catheter aspiration for simple pneumothorax (CASP) was evaluated prospectively in the outpatient management of simple traumatic pneumothorax in 17 patients and compared to conventional tube thoracostomy (CTT) in 17 matched control patients. In 16 of the 17 consecutive study patients CASP maintained lung reexpansion without complications. Pneumothorax was due to needle puncture for drug abuse in 11 patients, stab wounds in five patients, and blunt trauma in one patient. The CASP patients were not hospitalized, whereas the control CTT patients averaged 4.9 days' hospitalization. CTT was associated with complications in two patients versus none for CASP. Parenteral analgesics were utilized for greater than 48 hours in CTT patients but were not needed for CASP patients. Costs averaged +310 for CASP compared to +3,030 for CTT. This ongoing pilot study data indicates that CASP is a reasonable alternative to CTT in selected patients with simple traumatic pneumothorax.

Adolescent↗

A prospective analysis of occult pneumothorax, delayed pneumothorax and delayed hemothorax after minor blunt thoracic trauma.

OBJECTIVES: A prospective analysis was conducted to define the incidence of occult pneumothorax (OPX), delayed pneumothorax (DPX) and delayed hemothorax (DHX) and to propose an algorithm for surveillance. METHODS: During the last 2 years 709 consecutive patients who did not fulfill the indications for intrahospital management were examined at our emergency department for blunt thoracic injury. All patients were subjected to expiration posteroanterior chest radiograph (eCXR) and were scheduled for reevaluation after 24, 48 h and at 7, 14 and 21 days. RESULTS: OPX was present in 28 patients (4%) detected only with eCXR on admission, 14 patients developed DPX (2%) at 24-48 h later, and 52 patients presented up to 14 days later with DHX (7.4%). Of all DHX 42 (80.7%) required chest tube drainage, eight thoracentesis (16%) and only two (4%) were subjected after 1 month to decortication. No related morbidity was recorded. All the patients with the DHX had at least one rib fractured. Only one death among the DHX patients was documented. CONCLUSIONS: A safe algorithm is recommended: eCXR for every patient who suffered blunt thoracic injury with at least one rib fracture detected and is treated as an outpatient or in case his/her compliance with the reevaluation schedule will be suboptimal. Close follow-up is also suggested since these entities do exist, cannot be ignored and their treatment is early evacuation of the pleura cavity.

Adult↗

Uncertainties in the current understanding of gas exchange in spontaneous pneumothorax: effective lung ventilation may persist in a smaller-sized pneumothorax.

Clinical aspects of spontaneous pneumothorax (SP) are far more clear than some patophysiological issues. The exact mechanism that maintains adequate oxygenation in spontaneous pneumothorax of lesser size is still unclear. Experimental and rare studies in humans could not explicitely confirm whether it is hyperventilation of the nonaffected lung, still effective gas exchange within the affected lung, or hypoxic vasoconstriction. Similarly, it is unclear why the severity of dyspnoea sometimes differs between patients with the same size of SP. The idea that a certain degree of effective lung ventilation might exist in SP of lesser size was based on clinical observation of these patients on admission, on our measurements of pleural pressures and oxygenation in a group of patients with SP of different size and on rare experimental studies. Clinical observation that oxygenation was not significantly impaired in patients with SP of lesser size, without documented hyperventilation, served as a base for critical analysis of possible factors influencing oxygenation in SP of lesser size. Our hypothesis that pleural pressure swings in a partially collapsed lung, but still slightly expanding in inspiration, enable a certain degree of gas exchange, was confirmed both by several experimental studies and by our measurements. On the other hand, our clinical observation that patients with SP of greater size frequently differ in the severity of dyspnoea suggested the need of a more detailed analysis of the causes of hypoxaemia in these patients. The fact that hypoxaemia in these patients usually cannot be abolished by the existing hyperventilation, means that in SP of greater size, despite minimal lung volume, circulation in the pulmonary artery system still exists, causing right to left blood shunting. The fact that the severity of dyspnoea is not equal in all patients with complete SP means that hypoxic vasoconstriction exists only in some of them, following a still unknown pattern. Literature data and our measurements suggest that without further studies of hypoxic vasoconstriction in the acute phase of SP, the exact answer is not possible.

Carbon Dioxide↗

Tension pneumothorax and contralateral presumed pneumothorax from endobronchial intubation via cricothyroidotomy.

Cricothyroidotomy can be a life-saving procedure for the "can't intubate, can't ventilate" patient who has upper-airway obstruction. The procedure is usually fast and easy to do; however, complications have been reported. We report two cases in which cricothyroidotomy with an endotracheal tube led to unrecognized endobronchial intubation, ipsilateral tension pneumothorax, contralateral presumed pneumothorax, and unnecessary emergency surgery. Additionally, these led to the triad of hypotension, hypoxemia, and, probably, elevated intracranial pressure, which can worsen cerebral injury. We discuss methods to avoid these complications.

Adolescent↗

When is a pneumothorax not a pneumothorax?

The authors report on a 13-year-old boy who, after exercise, had respiratory distress and left upper quadrant abdominal pain. Initially, a mistaken diagnosis of pneumothorax was made, and a chest tube was inserted. A nasogastric tube was then visualized on chest x-ray in the left hemithorax. He underwent a laparotomy and had herniation of spleen, stomach, and large and small bowel in the left pleural space passing through a traumatic defect in the hemidiaphragm. The laparoscopic Nissen fundoplication 3 years prior was felt to have contributed. A timely and correct diagnosis is essential to avoid the sequelae associated with these injuries and with inappropriate tube thoracostomy.

Abdominal Pain↗

[Recurrent menstruation-associated pneumothorax--catamenial pneumothorax].

The case of a 28-year old patient with a rare complication of an extensive endometriosis externa is described. A spontaneous pneumothorax occurred on 3 occasions corresponding each time with the start of the menstrual period. The various hypotheses on the aetiology and treatment of this rare condition are reviewed. To date only 65 patients with this interesting clinical entity have been recorded.

Adult↗