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Results for “Plummer-Vinson Syndrome”

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At least 19 recordsLinked to original sources
PubMed1978

[Plummer-Vinson syndrome].

The Plummer-Vinson syndrome is very uncommon in Latin America. Four cases showing the clinical-radiological and hematological features of this syndrome are described. Three cases were treated with esophageal dilatation and Ferro therapy. The radiological evaluation may show deformities in the faringo-esophageal lumen other than the esophageal webs, such as hypertrophy of the cricopharingeal sphincter and of the retrocricoid venous plexus as well as the demonstration of esophageal webs in the patients without symptoms or signs of the Plummer Vinson Syndrome.

Adult↗
PubMed1979

Upper esophageal web due to a ring formed by a squamocolumnar junction with ectopic gastric mucosa (another explanation of the Paterson-Kelly, Plummer-Vinson syndrome).

A patient is presented with Barrett's esophagus (lower esophagus lined with columnar epithelium) who also has a band of columnar epithelium in the upper esophagus separated from that below by normal squamous epithelium in the midesophagus. The upper most squamocolumnar junction coincided with or formed a mucosal ring as seen at endoscopy. This ring, which was first seen on barium swallow, has the radiographic appearance of that associated with the Paterson-Kelly syndrome. This patient's unique findings may provide further insight into the etiology of upper esophageal webs or rings (Paterson-Kelly syndrome).

Aged↗
PubMed1976

[Benign diseases of the esophagus. An internist's view].

The work-up of patients with benign diseases of the esophagus should start with a diagnostic evaluation. This includes a carefully taken history, radiologic and endoscopic examinations and, in suspected reflux disease, recording of intraesophageal pH. For the evaluation of functional troubles esophageal manometry is recommended. Patients with complicated reflux disease and failures of antireflux treatment should be operated upon. In high peptic stenoses, Barrett's syndrome should be carefully looked for. Achalasia is treated by pneumatic dilatations with more than 90% good or satisfactory results. But diffuse esophageal spasm is little responsive to therapy. There is a risk of secondary carcinoma in Barrett's syndrome, achalasia, caustic lesions and Plummer-Vinson syndrome. Therefore these patients should be seen at regular intervals. There is an urgent need for controlled studies evaluating the comparative results of medical and surgical therapy.

Diagnosis, Differential↗
PubMed1978

Dysphagia.

Explore the source record for details and available documents.

Adult↗
PubMed1978

HLA-antigen frequencies in patients with a Plummer-Vinson stricture.

Factors of individual susceptibility seem to be involved in the occurrence of Plummer-Vinson stricture, which is a permanent stricture of the cervical esophagus associated with long continued iron deficiency. Fifty female patients with Plummer-Vinson stricture were HLA typed and the antigen frequencies were compared with those of 75 female blood donors from the same geographic area and of the same race. A comparison was also made with the HLA antigen frequencies of a group of 200 blood donors (75 female and 125 male). There were no statistically significant differences in the HLA antigen distributions of the three groups.

Adult↗
PubMed1977

[Oral leukoplakias. I. Classification, differential diagnosis, etiological conditions for neoplastic transformation, prognosis].

Leucoplakia is due to abnormal keratinization of squamous epithelial mucosa and constitutes a pattern of reaction of the oral mucosa which is typical for the tissue but unspecific for any stimulus. Because of its numerous causes leucoplakia cannot be defined as a pathologic entity. There is leucoplakia in the narrow sense and leucoplakia in the broad sense; the first should be regarded as a polyetiologic symptom but not as a disease in itself. Leucoplakias in the broad sense comprise those caused by well defined disorders. A classification of oral leucoplakias must include both categories, for differential diagnostic reasons. Therefore a classification of leucoplakias in the broad sense (hereditary 1., endogenous-irritative 1.) and leucoplakias in the narrow sense (exogenous-irritative 1., precancerous 1.) is proposed. The latter category is largely identical with the WHO definition of leucoplakia. The most important clinical and histological grounds on which this classification is based are explained. The precancerous lesions and the present knowledge of stomatology and oral pathology are particularly taken into consideration.

Alcoholism↗
PubMed1976

Nutrition and cancer.

There is increasing epidemiological evidence that nutrition plays a dominant role in the pathogenesis of several types of human cancers. There is considerable epidemiological evidence showing that alcoholism in part because of associated nutritional deficiencies, significantly increases the risk of smokers for cancer of the alimentary tract. There is also some suggestion that nutritional deficiencies may relate to cancers of the stomach, cervix, and thyroid. Of particular importance, and based on relatively new concepts, are data indicating that overnutrition significantly affects the development of certain cancers, including cancers of the colon and pancreas, kidney, breast, ovary endometrium, and prostate. Except for cancer of the endometrium, and kidney cancer in women, there is no significant relationship to obesity. Rather, the evidence suggests both epidemiologically and experimentally that the etiological factors relate to a high intake of fats and possibly other variables associated with high fat intake. While we are investigating the mechanistic nature of the epidemiological and experimental observations, the question that needs to be asked is whether it is not prudent for us to associate ourselves with the recommendation of our colleagues in the cardiovascular disease field who call on both individuals and the food industry to practice a "Prudent Diet," i.e., one that is lower in total calories, total fat, saturated fats and cholesterol than is the present American diet.

Alcoholism↗
PubMedDate not supplied

[Some rare diseases of the esophagus (author's transl)].

Cancer excepted all other diseases of the esophagus are rare. Diverticula, benign tumors, perforations and the pathology of the cardia (hiatus hernia, achalasia and esophageal varices) are not studied here. We took into consideration the following diseases only: spasm of the cricopharyngeal muscle, Plummer-Vinson or Kelly-Paterson syndrome, cervical osteophytosis, dysphagia lusoria, benign and malignant mediastinal lymphatic nodes, Schatzki ring of the lower esophagus and esophageal duplications.

Aged↗