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Results for “Pigmentation Disorders”

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At least 19 recordsLinked to original sources
PubMed1991

Melanin pigmentation disorders of the skin and oral mucosa.

Pigmented lesions in brown, blue-black, or variations of these colors are relatively rare in the oral cavity but very common in the skin and can range from absolutely benign to highly malignant. The differential diagnosis of brown and blue-black lesions of the oral cavity includes normal racial pigmentation, melanosis, nevi, melanoma, amalgam tattoos, and disorders related to the blood or blood vessels.

Adolescent↗
PubMed1992

Skin disorders in Indo-Chinese immigrants.

OBJECTIVE: To define and assess the relative frequency of the skin disorders which were seen in Indo-Chinese immigrants, and to describe in detail some of the interesting cases encountered. DESIGN: Retrospective review of case records of Indo-Chinese immigrants referred to the Lidcombe Hospital Dermatology Centre between October 1987 and March 1991. SETTING: Lidcombe Hospital. PATIENTS: Indo-Chinese immigrants assessed at the Lidcombe Hospital Dermatology Centre. RESULTS: One hundred and ninety patients were identified. The most common categories of skin disorders were disorders of pigmentation, disorders of sebaceous glands, and dermatitides. Disorders not often seen in the non-Indo-Chinese population (e.g., naevus of Ota, cutaneous tuberculosis and primary skin-limited amyloidoses) were also identified. No cutaneous malignant conditions were encountered. CONCLUSIONS: Chloasma and acne vulgaris are common dermatological disorders in Indo-Chinese immigrants. Cutaneous malignant diseases do not appear to be common in this population, in contrast to their common occurrence in Caucasian patients.

Amyloidosis↗
PubMed1992

[Culture of human melanocytes. Its contribution to the knowledge of melanocyte physiology].

Culture techniques for normal human melanocytes have been developed over the last ten years. This in vitro model for studying pigment-producing cells can be expected to provide major advances in the knowledge of cell-to-cell anc cell-to-matrix interactions, melanocyte and melanin biology, pathophysiology of pigment disorders, and malignant melanomas. Melanocyte cultures have already shed new light on keratinocyte-melanocyte interactions within the epidermal melanin unit by showing that keratinocytes produce "melanotrophic factors" which modulate growth, melanin production, and dendricity of melanocytes. Melanocyte cultures also enable in vitro studies of melanocyte responses to ultraviolet radiations and of the biologic messengers involved in these responses. Lastly, they provide a means for investigating endocrine and paracrine mechanisms involved in the regulation of melanogenesis, including the role of melanotropins, estrogens and vitamin D. Improved knowledge of the molecular biology of melanocytes provides hope for rapid advances in the understanding of tyrosinase and posttyrosinase regulation of melanogenesis. Lastly, melanocyte cultures can be expected to find useful applications in the pathophysiologic study of pigment disorders and of pharmacologic modulation of skin pigmentation.

Cells, Cultured↗