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At least 19 recordsLinked to original sources
PubMed1991

Biting periodicity index of Culex quinquefasciatus & its relationship with microfilaria periodicity in Pondicherry.

The biting periodicity index of the bancroftian filariasis vector, C. quinquefasciatus, was calculated on the basis of a large longitudinal data base and compared with the periodicity index of microfilariae of Wuchereria bancrofti. The biting periodicity index of the vector population was 29.78 and found to be close to the periodicity index of the microfilariae. The peak biting activity of the vector and peak appearance of microfilariae in the peripheral blood occurred at about 01.00 h, which accounts for the optimum infection of the vector population. The early night biting density of the vector population showed a highly significant (P less than 0.0005) linear relationship with all night biting density.

Animals↗
PubMed2005

[Journal selection and indexing for Index Medicus and Chinese periodicals indexed in Index Medicus].

Index Medicus/MEDLINE/PubMed published by U. S. National Library of Medicine (NLM) is the most important and commonly used biomedical literature retrieval system in the world. According to the"List of Journals Indexed in Index Medicus (2004)", 4,098 journals are indexed for Index Medicus, including 70 journals from mainland China and Hong Kong and 9 journals from Taiwan. Journal of Chinese Integrative Medicine established in May, 2003 is indexed in Index Medicus in 2004. This article outlines the critical elements of journal selection for Index Medicus/MEDLINE and the journal selection process for indexing at NLM, and introduces some measures for the Journal of Chinese Integrative Medicine being indexed in Index Medicus/MEDLINE.

China↗
PubMed2006

[A list and analysis of reproductive medicine periodicals indexed in MEDLINE in 2006].

MEDLINE established by National Library of Medicine (NLM), USA, is the most commonly used biomedical literature retrieval system, whose indexed literature generally represents the top of the medical world. Of the total number of 4959 journals listed in the Lists of Journals Indexed in MEDLINE (2006) published by NLM, 46 are periodicals of reproductive medicine, mainly including andrology, fertility, and sterility. Researchers of reproductive medicine should be familiar with the journals indexed in MEDLINE, closely follow their published frontier researches in this field, and consciously contribute to them in English. Editors of reproductive medicine journals should endeavour to have their journals included in such internationally authoritative systems as MEDLINE, SCI, etc by publishing them in English in compliance with international standards. This article presents a list of the reproductive medicine periodicals indexed in MEDLINE (2006) together with a brief analysis, which is meant to help researchers in reproductive medicine, andrology and other relevant fields with their contribution, subscription, reading and retrieving, as well as to share some more knowledge about MEDLINE and its indexed journals with Chinese editors of reproductive medicine journals.

Bibliometrics↗
PubMed2006

[Chinese periodicals indexed in MEDLINE in 2006].

For the first time, the Chinese Ministry of Science and Technology published an analysis report of Chinese papers indexed in MEDLINE, which indicates that the Chinese government is paying more and more attention to the role of MEDLINE in the evaluation of scientific research. A total of 4 959 journals are listed in the Lists of Journals Indexed in MEDLINE (2006) published by National Library of Medicine, USA (NLM), of which 95 are published in China (including Hong Kong and Taiwan) and 2 another Chinese periodicals are published abroad. To familiarize MEDLINE to more medical researchers and to help them contribute to the journals indexed in MEDLINE, this article lists the top 10 Chinese medical institution whose published papers were indexed in MEDLINE in 2004 along with the Chinese periodicals indexed in MEDLINE in 2006. And the status of MEDLINE in China is briefly analyzed as well.

Bibliometrics↗
PubMed2005

Effects of beta-cyfluthrin on white and sepia mutants of Drosophila melanogaster.

The effects of sublethal concentrations of a synthetic pyrethroid, beta-cyfluthrin (Bulldock 025 SC) were investigated in the F1 generations of white and sepia mutants of Drosophila melanogaster after various cross combinations of the parents which were exposed separately to the insecticide mixed diet for 24 hours. The experiment was carried out under the laboratory conditions at a temperature of 25+/-5 degrees C and 60+/-5% relative humidity. The insecticide had deleterious effect on the growth and development of both the mutant flies. Larval, pupal and total developmental periods were found to be increased as compared to controls, whereas the number of adult emerged decreased in all the treatment sets. Larval period index (LPI), pupal period index (PPI) and growth index (GI) were observed to be decreased in the entire cross combinations. Maximum effects were observed in those sets where both the sexes were treated, crossed and F1 generation was studied on the treated food having sublethal concentration of the insecticide, followed by similar treatment sets but on the fresh untreated food. Females were found to be resistant as compared to the males, whereas white mutant files were more susceptible to the test insecticide beta-cyfluthrin as compared to sepia mutant flies.

Animals↗
PubMed1979

Depression: factors related to 10-year prognosis.

The 10 years' course of a series of 83 moderately severe depressions is presented, as well as factors governing the clinical and work prognosis. Depression was the fundamental disturbance in 75 cases during the index period. The depression was endogenous in 67 cases, reactive in eight, and neurotic in six cases. In the follow-up the drop-out from personal examination was 6.4%. Twenty per cent of the patients had been (almost) entirely free from symptoms of depression during the period of observation, 5% had been continuously depressive. There were no suicides. Twenty-seven patients felt some decrease in working capacity during the depressions, but only seven were unable to continue their previous work and three had changed work to prevent relapses. Fourteen of the patients had been sick-listed for more than 1 year of the observation period. Favourable factors for long-term course were: high intellectual capacity (for work prognosis, W), afraid of hurting others (W), white collar work (W), slight depression of mood during index period (for clinical course, C), favourable immediate outcome after index period (W). Unfavourable factors for long-term course were: low intellectual capacity (W), hysteroid personality (C), syntonic personality (W), asthenic personality, sensitivity to praise (C), tendency to feel under observation (W), and some symptoms during the index period: tendency to seclusion (C), ideas of reference (C), dryness of mouth (C), difficulty in falling asleep (C), dreamlike feeling (C), supplicating attitude (C). The implications of the results for nosology, care, and prevention of depressive states are discussed.

Adult↗
PubMed2003

Use of system-wide outcomes monitoring data to compare the effectiveness of atypical neuroleptic medications.

OBJECTIVE: Outcomes monitoring data in a large health care system were used to evaluate the effectiveness of atypical neuroleptic medications in actual clinical practice. METHOD: National administrative data from the Department of Veterans Affairs were used to identify patients with schizophrenia who had no change in antipsychotic medication over a 3-month index period in 1999 and for whom Global Assessment of Functioning Scale ratings were available from both the index period and the following year (N=9,066). Analysis of covariance, including potentially confounding factors, was used to compare change in functioning scores between patients who continued to take the same medication and those whose medication was switched during the follow-up year. Among patients whose medication was switched, change in functioning scores was compared by whether patients received a conventional neuroleptic or each of the four then available atypical neuroleptics after the medication switch. RESULTS: Patients who continued to take the same medication (N=7,157, 78.9%) had improved functioning scores from the index period to the follow-up year, while patients whose medication was switched (N=1,909, 21.1%) had declining functioning scores (mean change in scores of 0.6% and -3.7%, respectively). Among the patients whose medication was switched, no significant differences in functioning were found between patients grouped by the new type of medication received. CONCLUSIONS: In this large administrative database, patients with schizophrenia whose neuroleptic medication was switched showed significantly less improvement in Global Assessment of Functioning Scale scores than patients who continued to take their original medication. No significant differences in functioning scores were found for patients whose medication was switched to any of the atypical neuroleptics.

Ambulatory Care↗
PubMed1981

Systemic and cardiac hemodynamic interactions between clonidine and minoxidil.

We examined the hemodynamic interaction between clonidine, a centrally acting antiadrenergic drug, and minoxidil, a potent antihypertensive vasodilator in 10 inpatients with refractory or accelerated hypertension or both. Clonidine in oral doses of 150 to 900 micrograms/day decreased average mean blood pressure 18.6 mm Hg (p less than 0.01), average heart rate 16.4 bpm (p less than 0.01), limb blood flow 1.63 ml/100 gm . min (p less than 0.05), and plasma renin activity 1.13 ng/ml . hr (p less than 0.025). It also increased the pre-ejection period index 12.4 msec (p less than 0.001), but did not alter the cardiac or total peripheral resistance indices. The addition of minoxidil in oral doses of 5 to 22.5 mg/day further decreased average mean blood pressure 24.2 mm Hg (p less than 0.01), preejection period index 20.6 msec (p less than 0.01), limb vascular resistance 13.2 mm Hg/min . 100 gm/ml (p less than 0.05), and total peripheral resistance 13.3 mm Hg/min . m2/l (p less than 0.01), pre-ejection period index 20.6 msec (p less than 0.01), limb vascular resistance 13.2 mm Hg/min . 100 gm/ml (p less than 0.05), and total peripheral resistance 13.3 mm Hg/min . m2/l concluded that clonidine can be used as an alternative to beta-adrenergic blockers to counteract the increased sympathetic nervous activity minoxidil induces.

Adult↗
PubMed2004

Periodic limb movements in children: prevalence in a referred population.

STUDY OBJECTIVES: To determine the prevalence of periodic limb movements of sleep (PLMS) in children referred for evaluation of sleep disorders. DESIGN: A retrospective analysis of all overnight polysomnograms (PSG) performed at a tertiary-level pediatric care facility. SETTING: All PSG studies were performed in the pediatric sleep laboratory associated with the Alberta Children's Hospital in Calgary, AB, Canada. The pediatric sleep laboratory was situated in the Foothills Hospital Alberta Lung Association Sleep Center until August 2002. At that time, the pediatric sleep laboratory was relocated to the Alberta Children's Hospital. PARTICIPANTS: All children of any age undergoing PSG for any reason between October 1999 and March 2003. MEASUREMENTS AND RESULTS: All PSG records were reviewed, and the following data was extracted: periodic limb movement index (PLM index), periodic limb movements with arousal index (PLM w/arousal index), apnea-hypopnea index (AHI), and patient demographics (age, sex, comorbidities). A total of 591 PSG studies were reviewed. Thirty-three of the 591 children (5.6%) had evidence of PLMs > 5 per hour. Twenty of the 33 (60.0%) had coexistent obstructive sleep apnea (AHI > 1/hour). Only 7 of the 591 children studied (1.2%) had evidence of PLM > 5 per hour with no other comorbidity. Two of 13 children with PLM > 5 per hour and no evidence of obstructive sleep apnea had attention-deficit/hyperactivity disorder. The prevalence of PLMS in the 28 of the 591 subjects with a preexisting diagnosis of ADHD was increased at 7.1%. CONCLUSIONS: PLMS is an uncommon disorder of childhood. In a select population at increased risk for having a sleep disorder, the prevalence of isolated PLMS is only 1.2%.

Child↗
PubMed1983

Non-invasive measuring of the circulatory effect of afterload reduction in order to monitor the pharmacodynamic effect of drugs in normal volunteers.

In order to measure the effect of a decrease in afterload on systolic time intervals, left ventricular end-systolic diameter, and left ventricular wall stress, eight healthy young persons underwent a randomised placebo controlled trial of terbutaline before and during atenolol treatment. Pre-ejection period index, left ventricular end-systolic diameter, and wall stress all decreased after terbutaline, the decrease being clearly dose dependent. This was identical before and during atenolol administration. Consequently the observed changes were induced by beta-2 elicited vasodilatation, possibly combined with some decrease of parasympathetic tone. A close correlation between changes in pre-ejection period index (PEPI) and changes in left ventricular end-systolic diameter (LVESD) and wall stress was shown both before and during atenolol treatment. When using non-invasive methods in the evaluation of changes in contractility, it is important to correct for changes in preload and afterload. For normal subjects it is suggested that the relation between delta PEPI and delta LVESD as a percentage of the mean values should be used for evaluation of afterload changes. A method is suggested for estimating changes in pre-ejection period index induced by changes in left ventricular end-systolic diameter or wall stress.

Adult↗
PubMed1981

Systolic time intervals in chronic severe anaemia and effect of diuretic and digitalis.

Systolic time intervals were measured from simultaneous high speed recordings of the electrocardiogram, phonocardiogram, and carotid artery pulse in 15 men with chronic severe anaemia not in heart failure and with a normal heart size, and in 15 normal men. Heart rates, electromechanical systole (QS2), pre-ejection period index (PEPI), left ventricular ejection time index (LVETI), and the ratio of pre-ejection period to left ventricular ejection time (PEP/LVET) did not differ significantly in the two groups. After the intravenous administration of frusemide in 10 of the anaemic patients, the pre-ejection period index was prolonged, the PEP/LVET ratio increased, heart rate increased, and the left ventricular ejection time index shortened. Intravenous digoxin did not alter the QS2 interval and heart rate significantly in the anaemic subjects. Left ventricular function in chronic severe anaemia as measured by systolic time intervals does not differ from that of normal controls. The effect of frusemide on the systolic time intervals is explained as an effect of the fall in preload, bringing cardiac function further down on the ascending limb of the Frank-Starling curve. Other related studies are discussed.

Adult↗
PubMed2001

The role of psychometric data in predicting inpatient mental health service utilization.

Inpatient mental health readmission rates have increased dramatically in recent years, with a subset of consumers referred to as revolving-door patients. In an effort to reduce the financial burden associated with these patients and increase treatment efficacy, researchers have begun to explore factors associated with increased service utilization. To date, predictors of increased service usage are remarkably discrepant across studies. Further exploration, therefore, is needed to better explicate the relevance of "traditional" predictors and also to identify alternate strategies that may assist in predicting rehospitalization. One method that may be helpful in identifying patients at high risk is the development of a psychometric screening procedure. As a means to this end, the present study was designed to assess the potential usefulness of psychometric data in predicting mental health service utilization. The sample consisted of 131 patients hospitalized during an index period of 8 months at an acute-care psychiatric hospital. Number of readmissions was recorded in a 9 month post-index period. Measures completed during the index admission included the Brief Psychiatric Rating Scale-Anchored (BPRS-A), Symptom Checklist-90-Revised (SCL-90-R), Kaufman Brief Intelligence Test (K-BIT), and the Beck Depression Inventory (BDI). Results indicated that psychometric data accounted for significant variance in predicting past, present and future mental health service utilization. The BPRS-A, SCL-90-R, and BDI show particular promise as time efficient psychometric screening instruments that may better enable practitioners to identify patients proactively who are at increased risk for rehospitalization. Implications are discussed with regard to patient-treatment matching and discharge planning.

Adult↗
PubMed2003

Periodic limb movements in sleep and iron status in children.

STUDY OBJECTIVES: To assess potential relationships between serum iron and ferritin levels and the severity of periodic limb movement in sleep (PLMS) in a pediatric population, and to evaluate the response to supplemental iron therapy. DESIGN: A prospective study of all consecutively diagnosed children with PLMS (periodic limb movement index [periodic limb movements per hour of total sleep time, [PLMI] > 5) who underwent overnight polysomnographic evaluation. In all patients, complete blood count and serum iron and ferritin levels were obtained. Patients with serum ferritin concentrations less than 50 microg/L were prescribed iron sulfate at 3 mg/kg of elemental iron per day for 3 months. At the end of treatment, serum iron and ferritin levels and sleep studies were repeated. SETTING: Comprehensive Sleep Medicine Center, Tulane University Health Sciences Center, and Kosair Children's Hospital Sleep Medicine and Apnea Center. PATIENTS: Twenty boys and 19 girls with PLMS with a mean age of 7.5 +/- 3.1 years. INTERVENTION: Iron therapy. RESULTS: Twenty-eight (71.8%) patients had ferritin levels less than 50 microg/L. There was no significant correlation between serum ferritin concentration and PLMS severity as indicated by the PLMI (r = -0.19). The PLMI in patients with serum ferritin levels less than 50 microg/L (29.9 +/- 15.5 PLM/h) was higher than in patients with serum ferritin levels greater than 50 microg/L (21.9 +/- 11.8 PLM/h); however, the difference did not achieve statistical significance (P = 0.09). In contrast, serum iron was significantly correlated with PLMI (r = -0.43, P < 0.01). Indeed, patients with serum iron concentrations less than 50 microg/dL had a higher PLMI compared to patients with serum iron concentrations greater than 50 microg/dL (42.8 +/- 18.3 PLM/h and 23.1 +/- 10.1 PLM/h, respectively; P = 0.02). Twenty-five out of the 28 PLMS patients with serum ferritin levels less than 50 microg/L received treatment with iron sulfate, and 19 (76%) responded favorably. Among the responders to iron therapy, PLMI decreased from 27.6 +/- 14.9 PLM per hour to 12.6 +/- 5.3 PLM per hour after 3 months of iron supplements (P < 0.001) and coincided with increases in serum ferritin levels (pre: 40.8 +/- 27.4 microg/L vs post: 74.1 +/- 13.0 microg/L; P < 0.001). CONCLUSIONS: In children, the presence of PLMS is frequently associated with low serum iron and a tendency toward low serum ferritin levels. In addition, iron therapy is associated with clinical improvement in most of these patients.

Adolescent↗