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At least 19 recordsLinked to original sources

Aerobic and anaerobic microbiology of periapical abscess.

Aspirates of pus from periapical abscesses in 39 patients were studied for aerobic and anaerobic bacteria. Bacterial growth was present in 32 specimens. A total of 78 bacterial isolates (55 anaerobic and 23 aerobic and facultative) were recovered, accounting for 2.4 isolates per specimen (1.7 anaerobic and 0.7 aerobic and facultatives). Anaerobic bacteria only were present in 16 (50%) patients, aerobic and facultatives in 2 (6%), and mixed aerobic and anaerobic flora in 14 (44%). The predominant isolates were Bacteroides spp. (23 isolates, including 13 Bacteroides melaninogenicus group), Streptococcus spp. (20), anaerobic cocci (18), and Fusobacterium spp. (9). Beta-lactamase-producing organisms were recovered from 7 of the 21 (33%) specimens that were tested. This study highlights the polymicrobial nature and importance of anaerobic bacteria in periapical abscess.

Adolescent↗

Predominant microflora associated with human dental periapical abscesses.

The microflora of periapical abscesses of teeth free of periodontal disease was studied. Permucosal aspiration of abscess contents and anaerobic cultural, microscopic, and biochemical techniques indicated a mixed but somewhat specific and relatively limited facultative and obligate anaerobic flora with Fusobacterium nucleatum and Streptococcus mitis as a frequent pair.

Adult↗

Intracranial complications of sinusitis in children. A sequela of periapical abscess.

The cases of two children with periapical abscess in the upper incisors, sinusitis, and intracranial abscess are described. The ethmoid and maxillary sinuses were involved in both patients. Subdural empyema occurred in both, and one of the children had also cerebritis and brain abscess. Anaerobic bacteria were isolated from the infected subdural empyemas. Peptostreptococcus intermedius and microaerophilic streptococci were recovered in one patient and Fusobacterium sp in the other. Surgical drainage and appropriate antimicrobial therapy resulted in complete eradication of the infection in both patients. The role of anaerobic bacteria and the therapy directed against them in periapical abscess and the sinusitis and intracranial abscess which follow are discussed.

Brain Abscess↗

Microbiology of periapical abscesses and associated maxillary sinusitis.

Aspirate of pus from 5 periapical abscesses of the upper jaw and their corresponding maxillary sinusitis were studied for aerobic and anaerobic bacteria. Polymicrobial flora were found in all instances, where the number of isolates varied from 2 to 5. Anaerobes were recovered from all specimens. The predominant isolates were Prevotella sp., Porphyromonas sp., Fusobacterium nucleatum, and Peptostreptococcus sp. Concordance in the microbiological findings between periapical abscess and the maxillary sinus flora was found in all instances. However, certain organisms were only present at one site and not the other. Five beta-lactamase-producing organisms were present in the five specimens. These data confirm the importance of anaerobic bacteria in periapical abscesses and demonstrate their predominance in maxillary sinusitis that is associated with them.

Adult↗

Periapical abscesses of cut canine teeth in cynomolgus macaques.

Periapical abscesses of canine teeth in a group of 47 male cynomolgus macaques are found to be associated with a procedure, involving cutting the canine teeth, used to make non-human primates less hazardous. Examination of 150 canine teeth in dry specimens revealed 30 cut teeth with no exposure of the pulpal chamber and 107 cut teeth where the dental pulp had been exposed. Of those teeth which had the pulpal chamber exposed by the cutting procedure, 85 (79.4%) showed clear evidence of osseous changes consistent with abscess formation in the apical regions.

Animals↗

Bacteriological study of root canals associated with periapical abscesses.

OBJECTIVE: The aim of this study was to identify microorganisms from root canals with periapical abscesses and to ascertain the susceptibility of Peptostreptococcus prevotii and Fusobacterium necrophorum to antimicrobials. Study design Thirty root canals were microbiologically sampled by using sterile paper points. The concomitant microorganisms were identified through the use of established methods. The susceptibility of P prevotii and F necrophorum to antimicrobials was evaluated by using the E test method. RESULTS: A total of 117 different bacterial strains were recovered, including 75 strict anaerobes or microphilic species. The most frequently isolated strict anaerobes were P prevotii, Peptostreptococcus micros, and F necrophorum. Facultative bacteria such as Gemella morbillorum and Streptococcus mitis were also found, albeit less frequently. The data revealed that P prevotii and F necrophorum were susceptible to the tested antibiotics. CONCLUSIONS: Gram-positive anaerobic bacteria predominate in the mixed microbiota of root canals with periapical abscesses. Moreover, P prevotii and F necrophorum are susceptible to the tested antibiotics.

Adolescent↗

Periapical abscesses: causal bacteria and antibiotic sensitivity.

The purpose of this study was to investigate the aerobic and anaerobic flora of periapical abscesses and evaluate their susceptibility to various antibiotics. In 52 patients, with a diagnosis of periapical abscesses, pus cultures were taken. Forty-two aerobes and 122 anaerobes were revealed, with 2 or more than 2 anaerobic strains isolated in 36 patients. Infections were purely aerobic in 6%, purely anaerobic in 17% and mixed in 75%, while in 2% of the specimens there was no growth of microorganisms. Among anaerobes, microorganisms from the Bacteroides group (38.5%), Peptostreptococcus spp. (24.6%), Peptococcus spp. (13.9%), and Fusobacterium spp. (4.1%), predominated in all cultures. Among aerobes the most prevalent bacteria were streptococci (47.6%) followed by staphylococci (35.6%) while Enterobacteriaceae were isolated in 4.8% of specimens. Selected susceptibility tests performed on several anaerobic species revealed that nitroimidazole derivatives, chloramphenicol and clindamycin retain their broad spectrum killing activity against anaerobes, followed by cefoxitin and moxalactam. Of the newer quinolones, ofloxacin was the most effective. It is evident that the high isolation rate of anaerobic bacteria should influence empiric therapeutic decisions.

Anti-Bacterial Agents↗

Comparison of the efficacy, safety and tolerability of azithromycin and co-amoxiclav in the treatment of acute periapical abscesses.

The activity, safety and tolerability of the azalide azithromycin were compared with those of co-amoxiclav in the treatment of acute periapical abscesses in adults in an open, randomized, multicentre comparative study. Patients of either sex, recruited from 106 dental practices in Belgium, were aged between 18 and 75 years and had acute periapical abscesses not requiring drainage, confirmed by radiology. Azithromycin was administered as a 500-mg tablet orally once daily for 3 days (n = 150) and co-amoxiclav as a 625-mg capsule three times daily, for 5-10 days (n = 153). Both before and after treatment, masticatory pain, percussion pain, headache, and oedema and redness of soft tissue were graded on a four-point scale. Overall clinical success (cure plus improvement) was seen in 131/144 (91%) evaluable patients receiving azithromycin and in 142/148 (96%) receiving co-amoxiclav (difference not significant). There was no significant difference between the two groups in the incidence or severity of adverse events or in the number of discontinuations because of adverse events.

Adolescent↗

The isolation and characterization of milleri group streptococci from dental periapical abscesses.

Reports of the isolation of streptococci from dental abscesses have shown an association of the "S. milleri" group with such lesions. There has been considerable confusion regarding the taxonomy of these organisms, but the milleri group has recently been reclassified into three distinct species: Streptococcus anginosus, Streptococcus constellatus, and Streptococcus intermedius. In this study, 45 samples from dental periapical abscesses were examined. Milleri group streptococci were isolated from 16 patients (37%), 15 being identified as S. anginosus and one as S. intermedius. In one patient, S. anginosus was isolated in pure culture, and it would appear that this is the predominant species of milleri group streptococci associated with periapical abscesses.

Adult↗

Maxillary sinusitis and periapical abscess following periodontal therapy: a case report using three-dimensional evaluation.

BACKGROUND: Maxillary sinusitis may develop from the extension of periodontal disease. In this case, reconstructed three-dimensional images from multidetector spiral computed tomographs were helpful in evaluating periodontal bony defects and their relationship with the maxillary sinus. METHODS: A 42-year-old woman in good general health presented with a chronic deep periodontal pocket on the palatal and interproximal aspects of tooth #14. Probing depths of the tooth ranged from 2 to 9 mm, and it exhibited a Class 1 mobility. Radiographs revealed a close relationship between the root apex and the maxillary sinus. The patient's periodontal diagnosis was localized severe chronic periodontitis. Treatment of the tooth consisted of cause-related therapy, surgical exploration, and bone grafting. A very deep circumferential bony defect at the palatal root of tooth #14 was noted during surgery. After the operation, the wound healed without incidence, but 10 days later, a maxillary sinusitis and periapical abscess developed. To control the infection, an evaluation of sinus and alveolus using computed tomographs was performed, systemic antibiotics were prescribed, and endodontic treatment was initiated. RESULTS: Two weeks after surgical treatment, the infection was relieved with the help of antibiotics and endodontic treatment. Bilateral bony communications between the maxillary sinus and periodontal bony defect of maxillary first molars were shown on three-dimensional computed tomographs. The digitally reconstructed images added valuable information for evaluating the periodontal defects. CONCLUSION: Three-dimensional images from spiral computed tomographs (CT) aided in evaluating and treating the close relationship between maxillary sinus disease and adjacent periodontal defects.

Adult↗

Periapical abscess formation and resolution adjacent to dental implants: a clinical report.

The vitality of teeth adjacent to dental implants should be considered in the treatment planning of dental implants. Both the restorability of an endodontically treated tooth and the risk of infection of the adjacent implant are important factors in planning for success. Given the illustrated difficulties and difficulties associated with resolving periapical infections of teeth and implants, it is essential to define the vitality of teeth by careful pulp testing and to consider the integrity of existing questionable, endodontically treated teeth before implant treatment. The risk of periapical infection at teeth adjacent to implants must be minimized.

Alveolar Bone Loss↗