Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Patient involvement”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1977

[Age, duration of disease and survival period of patients with involvement of the nervous system by malignant lymphomas. A statistical comparison of mycosis fungoides with lymphogranulomatosis (author's transl)].

A statistical comparison dealing with age, duration of disease and survival period of patients with involvement of the nervous system by malignant lymphomas revealed the following data: 1. With mycosis fungoides, involvement of the nervous system occurs later in life than with lymphogranulomatosis; this difference is statistically highly significant (P less than 0.001). 2. There is no statistical difference (P greater than 0.05) in the duration of either type of malignant lymphoma before the nervous system becomes involved. 3. It is of high statistical significance (P less than 0.001) that, once the nervous system has become involved, the survival period is lower with mycosis fungoides than with lymphogranulomatosis. It can be expected that involvement of the nervous system by mycosis fungoides leads with 79% probability (confidential limits 99% = 47.29--96.22%) to death within 6 months.

Age Factors↗
PubMed2026

Years of life lost in patients with a false-negative diagnosis of primary melanoma. A prospective study of the German Central Malignant Melanoma Registry involving 9063 patients over 28 years.

A false-negative diagnosis of cancer can lead to a delay in effective treatment and a poorer prognosis. Here, we use the example of cutaneous melanoma to examine how many years of life are lost after a false-negative diagnosis compared to a primarily correct diagnosis. From 1996 to 2015, 9,063 patients are prospectively registered in the German Central Malignant Melanoma Registry and followed up until December 2023. A false-negative diagnosis is found in 206 (2.3%) patients. The median time to correct diagnosis is 24.0 months. The 10-year recurrence-free survival probabilities are 32.9% for false-negative diagnoses and 76.2% for correct diagnoses (p&#x2009;<&#x2009;0.001). The 10-year melanoma-specific survival probabilities are 62.1% versus 85.0% (p&#x2009;<&#x2009;0.001). On average, each person with an initial false-negative diagnosis loses 8.2 years of life compared to people with a correct diagnosis. This high number of years of life lost raises the question of whether similar results also apply to other types of cancer.

Humans↗
PubMed1978

Echocardiographic detection of cardiac involvement in patients with chronic renal failure.

Echocardiography was performed in 50 patients in chronic renal failure with symptoms suggestive of possible cardiac involvement. Pericardial effusions were detected in 33 and pericardial thickening in 22. In five patients solid material, probably fibrinous, was seen adherent to the parietal or visceral pericardium. The left ventricle was dilated in 18 patients and showed definitely impaired contractility in 16. The left ventricular (LV) posterior wall was abnormally thick in 19 patients. In two, the ventricular septum was more than 1.3 times as thick as the LV posterior wall. Other echocardiographic findings included calcification in the mitral annulus region, mitral valve vegetations, and thickened chordae tendineae. Echocardiography has proved to be of great help in the assessment of symptomatic patients with chronic renal failure not only in diagnosing the presence and extent of pericardial effusion and thickening, but also in detecting impaired myocardial contractility, calcification in the posterior mitral annulus region, and vegetations of bacterial endocarditis.

Adolescent↗
PubMed1978

Central nervous system involvement in patients with rotavirus gastroenteritis.

Two children with rotavirus gastroenteritis are presented. The first case developed a fatal Reye's syndrome and the other one encephalitis with slow recovery. The rotavirus diagnosis was made in both cases by electron microscopy and a significant rise in antibody titres to Nebraska calf diarrhea virus was seen in one of the two patients.

Antibodies, Viral↗
PubMed1977

Oral feeding in the nutritional management of the cancer patient.

Nutritional therapy of the cancer patient by the oral route includes management of factors that may cause anorexia, attempts to modify the patient's eating behavior, and the offering of nutritional supplements to the patient. Anoretic factors for which specific strategies may be employed include taste abnormalities, pain, nausea, and depression. Modification of the patient's eating behavior involves patient education, monitoring, and feedback. Education includes nutritional instruction and instruction in favorable patterns for mealtime eating and stimulation of snack eating. Snack eating includes the use of nutritional supplements, and patient acceptance of commercially available supplements was studied. When synthetic chemically defined nutritional products were compared with milk-based product, patients preferred the milk-based product. Intercomparisons between milk-based products showed slight differences in preference ranking among these products and also differences between patients and controls in their relative order of ranking. Preference testing may be useful in assisting the health care team in selecting the optimal nutritional supplement to offer each patient.

Administration, Oral↗
PubMed1979

Drug related vasculitis. Clinicopathologic correlations in 30 patients.

Drug related vasculitis has variously been described as necrotizing hypersensitivity or allergic angiitis or microscopic panarteritis nodosa. We reviewed tissue sections from 30 patients with validated drug hypersensitivity and vasculitis in order to precisely define this entity. No evidence of necrotizing vascular lesions or of fibrinoid associated with necrosis was found. The vascular lesions in all 30 patients involved small arteries, arterioles, capillaries, and venules. The inflammatory infiltrate consisted primarily of mononuclear cells and prominent numbers of eosinophils and was present in all three layers of the involved vessel walls. Clinically the patients developed either localized or systemic vasculitis, which could not be predicted on the basis of the associated drug. The findings of a skin rash, fever, or eosinophilia and the development of symptoms consistent with a hypersensitivity reaction while medication was being taken were all suggestive of the diagnosis of drug related vasculitis.

Adolescent↗
PubMed1979

Transient left anterior hemiblock during angina pectoris: coronarographic aspects and clinical significance.

The data of 6 patients in whom a left anterior hemiblock appeared in the course of angina pectoris attacks were reviewed. All 6 patients were found to fulfill the criteria for unstable angina. 1 patient who presented the features of Prinzmetal variant angina was included in this group. Coronary arteriography showed significant coronary artery disease in all 6 patients involving 3 vessels in 2 patients, 2 vessels in 1 and 1 vessel in 3. A severe lesion (70--100%) of the left anterior descending artery in the vicinity of the first perforator was demonstrated in every case. The 2 patients with 3-vessel disease were not operable and died 4 and 5 days after the hemodynamic study. These deaths were caused by myocardial infarction with cardiogenic shock in one case and intractable ventricular arrhythmias in the other case. 4 patients were operable and underwent aortocoronary saphenous bypass surgery. There were 2 operative deaths. The 2 survivors are asymptomatic 7 and 16 mth after surgery. This study suggest that transient left anterior hemiblock during an attack of angina pectoris may be a feature of impending myocardial infarction and may be indicative of a severe obstruction of the left anterior descending coronary artery.

Adult↗