The dropout patient.
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A common problem in treating alcoholics is the high dropout rate. Many studies have identified individual factors associated with dropout, eg, poor motivation and previous dropout. We believe the present study reports the first major effort to use multivariate analyses to predict dropout in a large (792), one-year follow-up study of alcoholics, and examines the possibility that medical and nonmedical treatments lead to differential dropout rates. A multiple classification analysis technique showed that treatment variables as opposed to client characteristics were the best predictors of dropout. Patients remaining in treatment were more likely to have a variety of medical interventions, eg, medication and medical assessment, than those who dropped out. Results were similar to studies using other techniques and have interesting implications for the treatment of alcoholics, raising questions about current trends toward nonmedical treatment of alcoholism.
In a double-blind trial of six months' duration, a very high dose (VHD) regimen of fluphenazine decanoate (250 mg weekly) was compared with a standard dose (SD) regimen (12.5 mg weekly) in 50 chronic schizophrenic patients. The rating scales used included the Brief Psychiatric Rating Scale and the Wing Ward Behavior Scale. Both treatment groups improved during the trial, but there was no significant difference between them. The VHD regimen, however, exerted better control of the psychosis in that it had fewer patient dropouts and fewer "additional treatments" prescribed. Some of the patients receiving standard doses were probably not receiving adequate antipsychotic drug dosage. No predictors of clinical response could be defined. Extrapyramidal side effects were not significantly higher in the VHD group.
Product moment correlations were calculated between 17 psychosocial characteristics of 216 heroin addicts and their lengths of stay for first and second admissions to the dame methadone maintenance program. None of the variables which were related to retention during the first admission was associated with retention during the second admission. The conclusion was drawn that the relationships between addict characteristics and length of stay vary according to admission, and it would be unwise to use addicts' former treatment experiences to predict latter responses.
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The institution of a home peritoneal dialysis program has allowed us to increase the number of patients with end-stage renal failure entering our home dialysis program from 42.5% to 67.5% of the total population. This represents a 56.5% increase over the rate achieved by home hemodialysis alone. Twenty-four percent of the home peritoneal dialysis patients could have managed home hemodialysis, but 38 could not and this represents 48% of the total patients who entered our home dialysis program, for the period of the study. These patients would have required institutional dialysis which would not have been practical for 52.6% of them because of the distance they live from Toronto. The results of home peritoneal dialysis have compared favorably with home hemodialysis in the 2 concurrent but unmatched series in respect of training time, failure rate, need for in-hospital back-up and patient survival. A long-term study of matched patients randomized to either treatment group such as that described by Blumenkrantz will finally answer the question as to how valid is our contention that peritoneal dialysis compares favourably to hemodialysis for the treatment of end-stage renal failure.
A retrospective study of 820 rehospitalization of chronic schizophrenics in Greece showed no significant difference in the discharge-rehospitalization, discharge-relapse, and relapse-rehospitalization time intervals, between the patients who continued to receive their medication after discharge regularly, and the patients who discontinued their medication upon discharge. Furthermore, there seemed to be an increased social adaptability or tolerance of the psychotic behavior of the patients who had discontinued their medication, suggested by their longer relapse-rehospitalization time interval.
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The results from a prospective follow-up study of a group of schizophrenic patients suggest that a significant proportion (41 per cent) are likely to relapse during a two-year period despite the prescription of long-acting injectable neuroleptic drugs. Some will relapse because of a failure of the regime, but others (32-37 per cent) because the pharmacological protection of these drugs would appear to be less effective in certain patients. Even with the major advantages of the long-acting injectable neuroleptics over oral medication, the schizophrenic patient population remains a group with a high incidence of psychiatric and social morbidity which continues to require the full resources of both the hospital and community services.
The effectiveness of a community mental health programme in a developing country (Fiji) is examined. The programme was remarkable in that very little expertise was available in the community for it to be carried through. The results indicate that one category of hospital in-patient will subsequently derive significant benefit, namely the patient diagnosed as having schizophrenia who has been in a mental hospital more than once. Evidence from this study confirmed observations made by others that benign acute psychotic episodes are not infrequent in this sort of setting.
In a follow-up study of alcoholic patients, those with higher levels of denial had lower rates of rehospitalization and higher rates of treatment completion than those who relied on other defense mechanisms.
MMPI scores failed to predict treatment completion in alcoholics, but successful completion of treatment was related to lower relapse rates.