Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Pathology, Surgical”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed2021

Automated Extraction of Tumor Staging and Diagnosis Information From Surgical Pathology Reports.

PURPOSE: Typically stored as unstructured notes, surgical pathology reports contain data elements valuable to cancer research that require labor-intensive manual extraction. Although studies have described natural language processing (NLP) of surgical pathology reports to automate information extraction, efforts have focused on specific cancer subtypes rather than across multiple oncologic domains. To address this gap, we developed and evaluated an NLP method to extract tumor staging and diagnosis information across multiple cancer subtypes. METHODS: The NLP pipeline was implemented on an open-source framework called Leo. We used a total of 555,681 surgical pathology reports of 329,076 patients to develop the pipeline and evaluated our approach on subsets of reports from patients with breast, prostate, colorectal, and randomly selected cancer subtypes. RESULTS: Averaged across all four cancer subtypes, the NLP pipeline achieved an accuracy of 1.00 for International Classification of Diseases, Tenth Revision codes, 0.89 for T staging, 0.90 for N staging, and 0.97 for M staging. It achieved an F1 score of 1.00 for International Classification of Diseases, Tenth Revision codes, 0.88 for T staging, 0.90 for N staging, and 0.24 for M staging. CONCLUSION: The NLP pipeline was developed to extract tumor staging and diagnosis information across multiple cancer subtypes to support the research enterprise in our institution. Although it was not possible to demonstrate generalizability of our NLP pipeline to other institutions, other institutions may find value in adopting a similar NLP approach-and reusing code available at GitHub-to support the oncology research enterprise with elements extracted from surgical pathology reports.

Humans↗
PubMed1978

Specimen photocopying for surgical pathology reports.

A method of direct photocopying of surgical pathology specimens is described. The copy thus obtained can be included as a part of the surgical pathology report, to visually indicate locations of lesions, margins, measurements, and sites of sections taken for microscopic examination.

Copying Processes↗
PubMed1978

The "Scrimp" technique--a method for the rapid diagnosis of surgical pathology specimens.

A rapid cytological method for the diagnosis of surgical pathology specimens is reported. This procedure consists of a scrape of the tissue and an imprint of the cells and has therefore been termed the "Scrimp" technique. It is simple, inexpensive and accurate and is of value in routine surgical pathology in the separation of benign and malignant lesions and particularly in the determination of the adequacy of surgical excision of skin tumours.

Breast Diseases↗
PubMed1975

Surgical pathology of the spleen.

The indications for splenectomy in haematological and myeloproliferative disorders are now wider than before. An increased understanding of the concept of hypersplenism and a developing appreciation of the value of splenectomy in chronic leukaemia has been partially responsible for the increase. The principal factor, however, has been the advent of routine splenectomy as an integral part of the diagnostic process in Hodgkin's disease. This paper discusses these indications and their surgical pathology.

Hodgkin Disease↗
PubMed1977

Surgical pathology of schistosomal obstructive uropathy: a clinicopathologic correlation.

Schistosomal obstructive uropathy was studied by clinical, laboratory epidemiologic and pathologic analysis in 155 Egyptian patients treated surgically. Most patients were men; rural farmers or laborers. All had severe urinary schistosomiasis with heavy burdens of Schistosoma haematobium eggs in their urinary tracts. Schistosomal incomplete ureteral stenosis and schistosomal stenosis with ureterolithiasis were the most important obstructive lesions; these lesions were symmetrical and most frequent in the interstitial ureters decreasing proximally. The pathogenesis of these lesions is dependent upon focal destruction of ureteral muscle. The ureteral lesions proximal and consequent to schistosomal obstructive lesions are hydroureters resulting from active dilatation (due to increased hydrostatic pressure consequent to obstruction) and passive dilatation (due to loss of circular muscle action in sites of oviposition in the proximal ureter). Various combinations of these lesions with superimposed effects of bacterial infection and ureterolithiasis produce the spectrum of ureteral lesions attributable to urinary schistosomiasis.

Adult↗
PubMedDate not supplied

[Massive pulmonary hemorrhage in surgical pathology of the newborn infant].

Massive pulmonary hemorrhage is a complication which frequently leads to death in newborns with conditions susceptible to surgical treatment. Out of 112 postmortem studies, focal hemorrhage was found in 38 (33.9%) and massive in 34 cases (30.3%). In this series, congenital anomalies were found in digestive tract in 70.5% of the patients. Prematurity andlow weight were not important factors as was hypoxia, which was evident in 70.5% of the cases. Manifestations of respiratory insufficiency, shock, rales in lung fields, bleeding in other places different from the lung, blood leaking through upper respiratory ducts, are all clinical features of diagnostic aid. Disturbances in coagulation tests were detected, the same as drop in figures of hemoglobin, acidosis, hypoxia and hypercapnia. Gram-negative germs, with a predominance of Klebsiella, were isolated in 33 cultures. The radiographic finding with reticulogranular image was unfrequent. Among other precipitating factors of pulmonary hemorrhage, identification was made of the surgical disease by itself, surgical and anesthetic procedures, of ventilatory assistance and therapy with oxygen at high concentration for long periods of time.

Congenital Abnormalities↗
PubMed1977

[Odontological-surgical pathology in an Oslo population].

The present report deals with an investigation concerning the distribution of dental pathology in an Oslo population. The diagnoses are based on roentgenological findings in orthopantomograms from 216 individuals participating in the screening. The investigation contributes to knowledge about pathological conditions of the dentition and jawbones of a Norwegian population. Such knowledge is important for the assessment of the need of surgical intervention when programs for optimal oral health are planned.

Adult↗
PubMed1977

Trampolines and triangles. The surgical pathology of the vitreous.

The vitreous cavity may be invaded by cells penetrating through dehiscences in the inner limiting lamina of the retina, and exaggerated vitreo-retinal adhesions may also develop at such sites. The vitreous often separates from the inner limiting lamina except at these anomalous adhesions, and retinal traction thus results from excessive movement of the otherwise detached gel; traction on the retina may also follow proliferation and contraction of invading cells on the retinal surface, along the posterior hyaloid interface, or traversing the gel. Traction complications are liable to occur at sites of vitreo-retinal adhesion during surgical removal of opaque gel, while division of transgel strands and epiretinal or posterior hyaloid membranes may be necessary in order to relieve retinal traction.

Diabetic Retinopathy↗
PubMed1978

[Epidemiological study of emergency surgical pathology in the first aid department of a large hospital].

During a two-year period, major operations were performed on 874 males and 649 females at the first-aid section of a major hospital. Acute appendicitis was the most common intraoperative diagnosis (45.63%), followed by intestinal obstruction (21%), gastroduodenal perforation (6.83%), abdominal injury (5.98%), angiosurgical emergency situations (5.19%, including amputation for gangrene), gynaecological emergency situations (3.74%), acute cholecystitis (3.35%), haematemesis (1.44%), acute pancreatitis (1.31%), and various other diseases. Further surgery as a result of complications was required in 2.63%. Mortality (1 year only) was 7.42%. The results achieved and the tactical criteria employed are discussed.

Abdominal Injuries↗
PubMed1977

The surgical pathology of thoracic aortic aneurysms.

In 63 resected thoracic aortic aneurysms, the commonest histological finding (45 cases, 71.4%) was cystic medionecrosis. These cases formed two groups, 29 with widespread fragmentation and loss of elastic tissue (elastopathy) and 16 cases without elastopathy who were older and included most of the 18 cases of dissecting aneurysms. Thirteen patients had the Marfan syndrome, 10 showing cystic medionecrosis with elastopathy, indistinguishable from the cases with no Marfan stigmata although partial 'dissections' were mainly found in the Marfan patients, Histological appearances ranged from normal to complete loss of media. Cystic changes in muscle fibres apparently preceded elastic fragmentation. Fourteen cases (22%) had aortitis: 4 were syphilitic and 3 of other known aetiology. In 7 patients the aetiology of the inflammatory process was unknown and appearances included granulomatous infarct-like lesions and necrotizing aortitis or changes indistinguishable histologically from syphilis.

Adult↗