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At least 19 recordsLinked to original sources

Oral biopsy turnaround time: 20-year experience of the Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya.

The turnaround time (TAT) for oral biopsies received for histological examination by the Department of Oral Pathology, Oral Medicine and Periodontology, Faculty of Dentistry, University of Malaya, for the years 1978, 1988 and 1998 was evaluated. For the three years studied, TATs for 61, 233 and 463 specimens were retrospectively analysed. Testing intervals, that is, from the dates the surgeons procured the specimens, the laboratories accessioned them and until the pathologists signed off the diagnoses, were used to calculate TAT. The performance level of the respective pathologists, the growth of tissue diagnostic services and the possible variables that influence TAT were also evaluated. As prompt diagnosis means prompt treatment, which in turn has a bearing on prognosis, the TAT pertinent to oral malignant tumors was emphasized. The mean TAT, its mode and median fell significantly in 1998 compared with the previous 2 years; it was lower for soft tissue than for hard tissue specimens, and lower for malignant, than for non-malignant specimens. The progression of tissue diagnostic services is up to a satisfactory level, as 88.89 % of biopsies could render diagnoses within a fair period of time in 1998.

Biopsy↗

ORPAMS: a data-management system for oral pathology.

Oral pathology diagnostic services accumulate considerable clinicopathologic information on oral diseases/conditions. The authors describe an Oral Pathology Data-Management System (ORPAMS) designed for an oral tissue diagnostic program. Various features of data entry, manipulation, retrieval, and storage are outlined, and the research potential of the system is discussed.

Computers↗

Our challenge in oral pathology.

Oral pathology started as a specialty during the 1940s. At that time major problems existed in the diagnosis and treatment of diseases of the oral and facial regions. Today, it is important to be able to distinguish between benign and malignant diseases of the oral and facial regions. The head and neck regions have special embryonic and histogenetic factors that may contribute to diseases not seen elsewhere. This article will discuss the many challenges that face the specialists in oral pathology.

Education, Dental↗

Evidence-based practice of oral pathology and oral medicine.

Oral pathology is the specialty area of dentistry that deals with the diagnosis and management of oral diseases and more specifically, diseases other than dental caries, periodontal disease, restorative dentistry, and orthodontic therapy. Oral medicine represents the clinical arm of oral pathology and deals with diagnosis and treatment of soft-tissue lesions, whereas oral histopathology is the specialty area that focuses on the microscopic diagnosis of soft- and hard-tissue lesions of the head and neck area. The diagnosis and treatment of oral pathologic conditions is often based on empirical decision-making and many approaches to treatment have not been well-supported by clinicopathologic studies. The need for evidence-based, scientifically documented approaches to both diagnosis and treatment is eminent. Specific diagnostic criteria are lacking for many oral diseases, and therapeutic strategies have not been assessed by the gold standard of placebo-controlled, double-blind trials. Additionally, there are scientific data in the published literature that continue to be ignored by dental practitioners who manage patients with oral pathologic conditions. In this article, specific disease entities that are commonly managed by oral pathologists and oral medicine practitioners will be discussed with recommendations for future scientific studies that can serve as a framework for evidence-based diagnostic and therapeutic approaches.

Epithelium↗

The clinical-pathologic forum in oral pathology.

A clinical-pathologic "forum" has been employed for the past three years as the laboratory component of the predoctoral course in oral pathology at the University of Connecticut School of Dental Medicine. In addition to instruction in oral histopathology, this format provides an effective matrix for the development of descriptive skills and diagnostic discipline in clinical problem solving. The method is described and discussed.

Education, Dental↗

Facial pain of neurologic origin mimicking oral pathologic conditions: some current concepts and treatment.

A variety of pain syndromes of the face can arise from extradental pathologic conditions that can, at times, be confusing. Awareness of pain syndromes of neurologic origin that can mimic pathologic dental conditions is helpful. When doubt persists, rather than extract or endodontically treat a tooth, injection of a local anesthetic to the most sensitive areas can be a helpful diagnostic test. We recognize that there are many entities, including dental and temporomandibular joint syndromes, that much more often account for facial pain. However, we believe that those who most often treat these patients should also be aware of some of the advances in the understanding of the causes and treatment of the neurologic syndromes that can mimic pathologic oral conditions.

Adult↗

S-100 protein in normal and pathologic oral tissues. A review.

S-100 protein is an acidic calcium binding protein widely distributed in different tissues and cells of different origin. The precise biological role of S-100 is still unknown, but several features suggest a function activity for this protein. Oral tissues have not been extensively studied for S-100 protein presence. Here, we review the investigations of S-100 protein content in normal oral tissues and oral pathological lesions. The immunolocalization of this protein is used to demonstrate evidence of neuroectodermal histogenesis and is useful in the differential diagnosis of certain neoplasms or proliferative conditions.

Gingiva↗