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High-producing Landrace-Large White crossbred gilts (n = 50) involving 198 farrowings were used to evaluate dietary gestation protein (13 vs 16% CP) and gestation feed intakes (Control vs High), and their interaction, over a five-parity period on sow reproductive performance. Gestation feed intake for Control was 1.81 kg/d during parity 1, increasing by .09 kg for each successive parity. The daily feed intake for High was greater by .13 kg or approximately 450 kcal ME at each respective parity. The experiment was a 2 x 2 in a randomized complete block design conducted in two replicates with parity nested within sow groups. Sow weights and backfat thickness were determined at various intervals. A lactation diet containing .90% lysine in parity 1 and .80% lysine during parities 2 to 5 was fed to all sows from farrowing to weaning (21 d). Sow and pig weights, feed intakes, and colostrum and 21-d milk samples were collected during each lactation. The High feed intake and the 13% protein diet resulted in greater (P < .01) backfat thicknesses, and the effects were additive. Backfat thickness declined quadratically (P < .01) by parity and from late gestation to the rebreeding period of the following parity. The High feed intake resulted in a larger litter size (P < .01), whereas dietary gestation protein concentration had no effect on parturition performance. Sows in each parity consumed more (P < .01) feed from 0 to 7 d postpartum and for the overall 21-d lactation period (P < .01) for parity 1 when the 16% gestation protein had been fed. Gestation feed intake regimens did not affect lactation feed intake. Neither gestation variable affected colostrum or 21-d milk fat, but concentrations declined (P < .01) in all groups after parity 2. Parity 1 litters were heavier at 14 and 21 d, with larger litter gains from 0 to 14 and 0 to 21 d when gestating sows had been fed the 16% protein and the High feed intake combination compared to the other sow treatment groups. From parity 2 to 5, litter weights and gains were similar for all treatment groups. This resulted in a three-way interaction response (P < .05) for these variables. These results suggest that primiparous sows required a greater gestation protein concentration and greater feed intake than generally recommended, but the 13% CP diet at the High feed intake was effective in older sows.
Estimates of heritabilities and genetic correlations for calving ease over parities were obtained for the Italian Piedmontese population using animal models. Field data were calving records of 50,721 first- and 44,148 second-parity females and 142,869 records of 38,213 cows of second or later parity. Calving ability was scored in five categories and analyzed using either a univariate or a bivariate linear model, treating performance over parities as different traits. The bivariate model was used to investigate the genetic relationship between first- and second- or between first- and third-parity calving ability. All models included direct and maternal genetic effects, which were assumed to be mutually correlated. (Co)variance components were estimated using restricted maximum likelihood procedures. In the univariate analyses, the heritability for direct effects was .19 +/- .01, .10 +/- .01, and .08 +/- .004 for first, second, and second and later parities, respectively. The heritability for maternal effects was .09 +/- .01, .11 +/- .01, and .05 +/- .01, respectively. All genetic correlations between direct and maternal effects were negative, ranging from -.55 to -.43. Approximated standard errors of genetic correlations between direct and maternal effects ranged from .041 to .062. For multiparous cows, the fraction of total variance due to the permanent environment was greater than the maternal heritability. With bivariate models, direct heritability for first parity was smaller than the corresponding univariate estimate, ranging from .18 to .14. Maternal heritabilities were slightly higher than the corresponding univariate estimates. Genetic correlation between first and second parity was .998 +/- .00 for direct effects and .913 +/- .01 for maternal effects. When the bivariate model analyzed first- and third-parity calving ability, genetic correlation was .907 +/- .02 for direct effects and .979 +/- .01 for maternal effects. Residual correlations were low in all bivariate analyses, ranging from .13 for analysis of first and second parity to .07 for analysis of first and third parity. In conclusion, estimates of genetic correlations for calving ease in different parities obtained in this study were very high, but variance components and heritabilities were clearly heterogeneous over parities.
OBJECTIVE: To examine the risk of placental abruption, placenta previa, and uterine bleeding of unknown etiology in relation to advanced maternal age and parity in a large, population-based study. METHODS: Data for this study were derived from the Nova Scotia Atlee perinatal provincial data base, Canada, an ongoing project on human reproduction. Women who delivered between 1980 and 1993 (n = 123,941) in the province of Nova Scotia were included in the study, with the exception of pregnancies resulting in multiple births (n = 2859) and those missing data on maternal age or parity (n = 14). Multivariable logistic regression models based on the method of generalized estimating equations were used to generate odds ratios after adjustment for multiple confounders. RESULTS: The frequency of abruption was increased slightly among younger women (relative risk [RR] 1.3, 95% confidence interval [CI] 1.0-1.7), compared with women ages 25-29 years, but there was no increase with advancing maternal age. In contrast, the risk of placenta previa increased dramatically with advancing maternal age, with women older than 40 years having a nearly ninefold greater risk than women under the age of 20, after adjustment for potential confounders, including parity. Uterine bleeding of unknown etiology was not associated with advanced maternal age, except for a slight increase among women over 40 (RR 1.3, 95% CI 1.0-1.6). The risk of placenta previa and placental abruption was increased with higher parity among younger women only, but uterine bleeding of unknown etiology was more weakly associated with higher parity. In addition, an analysis of the joint effects of age and parity on placental abruption indicated a strong parity effect for women under 30 years, whereas the risk of placenta previa increased with increasing parity up to age 35 years. Uterine bleeding of unknown etiology also indicated a parity effect that was restricted to women under 25 years. CONCLUSION: Multiparity is associated with the risk of placenta previa and, to a lesser extent, placental abruption, but not with other uterine bleeding. Increasing maternal age is associated independently with the risk of placenta previa, but not with either of the other two conditions. Finally, the increased risks of uteroplacental bleeding disorders with advanced parity among the younger women (ie, 20-25 years, parity 3+) may reflect effects of close pregnancy spacing, or confounding by unmeasured factors that characterize women who have many pregnancies at a relatively young age. Overall, the findings suggest that the three uteroplacental bleeding disorders do not share a common etiology in relation to maternal age and parity, and that placenta previa is linked to aging of the uterus and the effects of repeated pregnancies.
OBJECTIVE: To examine how the relationship between parity increase and weight gain is modified by sociodemographic and behavioral factors. DESIGN: Prospective longitudinal data from the first National Health and Nutrition Examination Survey (NHANES I, 1971-75) and its follow-up of those aged 25 y and older, the NHANES I Epidemiologic Follow-up Survey (NHEFS, 1982-84). SUBJECTS: The analytical sample was nationally representative of the United States and included 2952 white or African-American non-pregnant women aged 25-45 y at baseline, who were re-measured approximately 10 y later. MEASUREMENTS: Statistical interactions in multiple linear and logistic regression models were examined to identify how eight sociodemographic and three behavioral factors modified the effect of parity increase on body weight change and risk of substantial weight gain. RESULTS: Factors that increased parity-associated weight gain included being African-American, living in a rural area, not working outside the home, having fewer children, lower income and lower education, and being unmarried. Among white women, being younger and having higher body weight at baseline increased parity-associated weight gain, while among African-American women, being older and having lower body weight increased parity-associated weight gain. African-American smokers gained less weight with an increase in parity, while the interactions between smoking and physical activity with parity-associated weight gain in whites were complex. CONCLUSION: The effects of sociodemographic and behavioral factors on parity-associated weight gain varied by race and parity change, with the most consistent findings being that unmarried and unemployed white women had greater parity-associated weight gain, while both white and African-American women who smoked, had higher education, or higher parity had lower parity-associated weight gain. This information may contribute to better targeting and more effective interventions to prevent postpartum weight retention.
The present study was performed to evaluate retrospectively the influence of birth litter size, birth parity number, performance test parameters (growth rate from birth to 100kg body weight and backfat thickness at 100kg body weight) and age at first mating (AFM) of gilts on their reproductive performance as sows. Traits analysed included remating rate in gilts (RRG), litter size, weaning-to-first-service interval (WSI), remating rate in sows and farrowing rate (FR). Data were collected from 11 Swedish Landrace (L) and 8 Swedish Yorkshire (Y) nucleus herds and included 20712 farrowing records from sow parities 1-5. Sows that farrowed for the first time during 1993-1997, having complete records of performance test and AFM, were followed up to investigate their subsequent reproductive performance until their last farrowing in 1999. Analysis of variance and multiple regression were applied to continuous data. Logistic regression was applied to categorical data. The analyses were based on the same animals and the records were split into six groups of females, i.e. gilts, primiparous sows, and sows in parities 2-5, respectively. Each additional piglet in the litter in which the gilt was born was associated with an increase of her own litter size of between 0.07 and 0.1 piglets per litter (P<0.001). Gilts born from sow parity 1 had a longer WSI as primiparous sows compared with gilts born from sow parity 4 (0.3 days; P<0.05) or parity 5 (0.4 days; P<0.01). Gilts with a higher growth rate of up to 100kg body weight had a larger litter size (all parities 1-5; P<0.05), shorter WSI (all parities 1-5; P<0.05) and higher FR (parities 2 and 5; P<0.05) than gilts with a lower growth rate. Gilts with a high backfat thickness at 100kg body weight had a shorter WSI as primiparous sows (P<0.001) compared with low backfat gilts, and 0.1 piglets per litter more as second parity sows (P<0.01). A 10 day increase in AFM resulted in an increase in litter size of about 0.1 piglet for primiparous sows (P<0.001) and a decrease (P<0.05) for sow parities 4 and 5.
OBJECTIVE: To investigate the preliminary observation that primigravid women have higher hCG multiples of the median (MoM) than multigravid women. METHODS: An analysis of the effect of gravidity and parity on maternal serum alpha-fetoprotein (MSAFP) and hCG was performed using data from 20,009 consecutive singleton pregnancies of 15-20 weeks' gestation in a maternal serum screening program. RESULTS: The human chorionic gonadotropin MoM for primigravid women was 0.1 MoM higher than for multigravid women. As parity or gravidity increased, maternal serum hCG decreased. The median hCG MoM for nulliparous women was 1.05, compared with 0.94 MoM for para 3 women. The decrease in hCG was similar at each gestational week from 15-20. In contrast, MSAFP and MSAFP MoM were unaffected by parity. Maternal age and race were potential contributing factors to the effect of parity. However, the decrease in hCG MoM with parity was observed within each 5-year increment of maternal age. Similarly, both black and non-black populations displayed decreases in hCG with parity, although black women had a consistently higher MoM in all matched sets. The decrease in hCG MoM with parity was also observed in 50 Down syndrome cases. Correcting patient data for parity resulted in the hCG MoM changing only 2.7% on average. The detection rate for the 50 Down syndrome cases would not have changed. CONCLUSION: The decrease in maternal serum hCG with increasing parity demonstrates that pregnancy history influences the level of maternal serum hCG. Further studies are needed to define the contributing factors, but the impact of parity on Down syndrome screening appears to be small.
Risk of recurrence of repeat breeding in sows with a repeat breeding in the 1st parity was investigated in 241 sow herds (1985-1990). The association between repeat breeding in the 1st and subsequent parities was examined using data on 9,120 sows. Each sow contributed only one pair of observations to the total data set. Occurrence of repeat breeding in the 1st and higher parities was presented in terms of recurrent risk rates (rRR), adjusted for different strata of herds. Sows with a repeat breeding in the 1st parity did not have a significantly higher risk rate for recurrence of a repeat breeding in the 2nd parity (rRR = 1.12, 95% confidence interval .97-1.29) and in the 3rd parity (rRR = 1.10, 95% confidence interval .86-1.41) compared to sows without a repeat breeding in the 1st parity. Sows with a repeat breeding in the 1st parity had a slightly higher risk rate for recurrence of a repeat breeding in the 4th or higher parity (rRR = 1.07, 95% confidence interval 1.03-1.10), compared to sows without a repeat breeding in the 1st parity. However, this risk is, in a biological sense, very small.
The influence of 7 factors on litter size for the combined parities 3 through 7 (age at conception of the first litter, parity-1 litter size, duration of lactation in the preceding parity, weaning-to-conception interval in the preceding parity, farrowing-to-conception interval in the preceding parity, number of matings per conception, and month of conception) was investigated in 11,929 litters from 5 commercial herds. Age at conception of the first litter did not influence litter size in these parities in any herd. In the 4 herds that kept such data, duration of lactation negatively influenced the weaning-to-conception interval, and duration of lactation and weaning-to-conception interval positively influenced the litter size in the next parity. Because the effects of duration of lactation and weaning-to-conception interval could not be investigated separately, their effects on litter size were simultaneously investigated, using the farrowing-to-conception interval for these combined parities. In all herds except one, the increase in live litter size was between 0.02 and 0.09 pig for each day increase in the preceding farrowing-to-conception interval less than 36 days (P less than 0.05). Duration of lactation within this farrowing-to-conception interval similarly influenced litter size. Litter size in litters of any herd was not affected by a preceding farrowing-to-conception interval greater than 35 days. In all herds except one, mean litter size of females with a farrowing-to-conception interval greater than 35 days was 0.26 to 0.96 pig greater (P less than 0.1) than for females with a farrowing-to-conception interval greater than 36 days. In 1 of 3 herds that kept such data, 2 matings per conception resulted in a larger mean live litter size than 1 or 3 matings (P less than 0.05). When these females were grouped on the basis of their conception during one of the 3-month seasonal periods, no influence of season on litter size was found. The effect of parity-1 litter size on litter size of subsequent parities 3 through 7 was significant. The regression coefficient ranged from 0.11 to 0.22 (P less than 0.01) in the farrowing-to-conception interval less than 36 days in all herds. In females with a farrowing-to-conception interval greater than 35 days, this association was significant only in one herd.(ABSTRACT TRUNCATED AT 400 WORDS)
The independent associations between parity and maternal body mass index (BMI), and between parity and maternal weight gain, were investigated using a combination of cross-sectional and longitudinal analyses based on a retrospective, repeat-pregnancy study that examined the change in maternal body weight from the beginning of one pregnancy to the beginning of the next. A group of 523 multiparous women who had been weighed regularly during pregnancy, and none of whom had fallen pregnant less than 12 months after the birth of their previous child, were examined. Sociodemographic, behavioural, medical, obstetric and perinatal data, together with antenatal measurements of maternal body weight and height, were abstracted from each mother's obstetric notes. Parity was found to be independently associated with maternal BMI (p < 0.001), gestational weight gain (p < 0.001) and interpregnancy weight gain (p = 0.032). Women of different parities were found to be at differential risk of long-term weight gain for two reasons. First, primiparous women are at risk of long-term weight gain because they gain the most weight during pregnancy, and high gestational weight gain is in itself a risk factor for long-term weight gain. Second, women of higher parity (4+) are at risk of long-term weight gain because they gain more weight in association with pregnancy, irrespective of the amount of weight they gain during their pregnancies. For women of parity 3 or less, the association between maternal body weight and parity appears to be the result of cumulative weight gained during successive pregnancies. For women of greater parity, the association between maternal body weight and parity is partly the result of cumulative excess gestational weight gained during successive pregnancies, and partly the result of gaining more weight from the beginning of one pregnancy to the next at later pregnancies.
Lactation measures of somatic cell concentration and total SCC production were developed. Data were separated into three parity groups. Within parity, five data sets were created: four subsets by herd-year average SCC, and one with all records. Records on lactation SCC, total SCC production, and 305-d milk were analyzed by a sire model separately in each subset within parity. Variance components estimates were by REML. For SCC and total SCC production, heritability estimates averaged .12 and were lowest in the highest level of herd-year average SCC. Estimates of genetic correlation between SCC and total SCC production were over .95; between SCC and 305-d milk were around .25 in first and -.15 in later parities; between total SCC and 305-d milk were around .50 in first and .15 in later parities. Product-moment correlations between sire effects in different levels of herd-year average SCC were obtained. Ratios of product-moment correlations to their expected value were above .80 for all traits in all parities. High ratios indicated little genotype by environment interaction. A sire by herd interaction was fitted in the model and accounted for less than 2% of total phenotypic variance for SCC and total SCC production, and 4% for 305-d milk. Estimates of genetic correlation of first with later parities were .71 to .86 for all traits. Between second and third parity genetic correlation estimates were around unity for all traits. Records from all parities should be used for sire evaluation.
Anthropometric data are presented on 412 rural Gambian infants measured longitudinally from birth to 18 months of age. Maternal parity was shown to exert a marked influence on growth. Firstborn babies had significantly depressed birthweights (parity 1: 2.79 +/- 0.06 kg, n = 62; parities 2-9: 3.05 +/- 0.09 kg, n = 309; P less than 0.001) but catch-up growth was complete by 3 months. In contrast, children born to mothers of very high parity (10 and above) had average birthweights (2.90 +/- 0.07 kg, n = 41) but early growth was poor. At 3 months their weights, mid-upper arm circumferences and triceps skinfolds were significantly below those of other infants (eg, weight-for-age (% NCHS): parities 10+: 90.3 +/- 2.3 per cent; parities 2-9: 97.4 +/- 2.7 per cent; P less than 0.01). Supine length and head circumference were not affected. After 3-6 months all children experienced severe growth retardation reflected in poor weight, length and head circumference gains. No catch-up growth occurred in the high parity group. Consequently, anthropometric differentials set up by 3 months were maintained throughout infancy (eg, weight-for-age at 12 months: parities 10+: 76.4 +/- 1.9 per cent; parities 2-9: 81.5 +/- 2.6 per cent; P less than 0.01). The relationship between these infant growth patterns and maternal lactational performance is discussed.
The parity effect in arithmetic problem verification tasks refers to faster and more accurate judgments for false equations when the odd/even status of the proposed answer mismatches that of the correct answer. In two experiments, we examined whether the proportion of incorrect answers that violated parity or the number of even operands in the problem affected the magnitude of these effects. Experiment 1 showed larger parity effects for problems with two even operands and larger parity effects during the second half of the experiment. Experiment 2 replicated the results of Experiment 1 and varied the proportion of problems violating parity. Larger parity effects were obtained when more of the false problems violated parity. Moreover, all three effects combined to show the greatest parity effects in conditions with a high proportion of parity violations in problems containing two even operands that were solved during the second half of the experiment. Experiment 3 generalized the findings to the case of five rule (i.e., checking whether a false product ends in 5 or 0), another procedure for solving and verifying multiplication problems quickly. These results (1) delineate further constraints for inclusion in models of arithmetic processing when thinking about how people select among verification strategies, (2) show combined effects of variables that traditionally have been shown to have separate effects on people's strategy selection, and (3) are consistent with a view of strategy selection that suggests a bias either in the allocation of cognitive resources in the execution of strategies or in the order of execution of these strategies; they argue against a simple, unbiased competition among strategies.