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Results for “PUBIC SYMPHYSIS”

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At least 19 recordsLinked to original sources

Osteomyelitis of the pubic symphysis in pregnancy.

BACKGROUND: Pubic symphysis osteomyelitis during the antepartum period of pregnancy is rare. CASE: We report a patient in the third trimester who presented with pubic pain, low-grade fever, and altered gait. She was found to have a retropubic abscess at the time of cesarean delivery. Radiologic imaging showed findings consistent with osteomyelitis of the pubic symphysis and multiple pus collections in the pelvis and labia. The patient was treated with surgical debridement of the affected bone and placement of antibiotic-impregnated beads. CONCLUSION: Osteomyelitis of the pubic symphysis can have serious complications. The diagnosis should be considered in pregnant patients with clinical findings unusual for pubic symphysis diastases. It can be treated with antibiotic-impregnated beads.

Adult↗

[The micro- and ultrastructural organization of mineralized cartilage in the human pubic symphysis].

Samples of the pubic symphysis of humans from 18 to 87 years of age were studied at the light- and ultramicroscopic levels. The structural organization of the mineralized cartilage were investigated in mutual relationship with the basophilic line of calcification and the subchondral bone. The front of mineralization of the public symphysis cartilage is formed by calcified capsules of chondrocytes, thick and thin bundles of mineralized collagen fibers, mineral granules in the interterritorial matrix of the cartilage. In humans aged from 20 to 29 years the front of mineralization of the pubic symphysis cartilage is intermittent, by 40-49 years the amount of gaps becomes less, at the age of 70-79 years the front of mineralization becomes intermittent again. In elderly and senile people mineral plates of complex configuration appear in the interterritorial matrix and chondrocyte capsules, by the age of 87 there appear thick highly mineralized bundles of collagen fibers.

Adolescent↗

Pubic symphysis sclerosis in psoriatic arthritis. Case report.

Pubic symphysis sclerosis is a very interesting event in psoriatic arthritis (PsA). PsA is a cronical arthritis, associated with psoriasis, classified with seronegative spondyloarthrities. There are 5 clinical PsA patterns: an oligoarticular pattern, characterized by asymmetrical involvement of metacarpophalangeal and interphalangeal joints of hands and feet, as well as ankles and knees; a polyarticular pattern; a pattern characterized by involvement of distal interphalangeal joints; an arthritis mutilans pattern, characterized by acro-osteolysis of distal phalanxes; a pattern with spondylitic involvement. Although pubic involvement in PsA is not described in literature, a lot of authors describe the presence of erosive and/or sclerotic osteitis pubis in seronegative spondyloarthrities, without a more accurate subclassification. In seronegative spondyloarthrities sclerotic involvement of pubic symphysis has been described in patients suffering from ankylosing spondylitis for 5-10 years. A case of pubic symphysis sclerosis, evident on radiographs and detected also by magnetic resonance, which shows also a pattern of oedema and enhancement, with increased signal intensity on pubic symphysis in T2-weighted images, after the contrast agent was injected in the bone marrow, is reported in a woman affected by PsA. Pubic symphysis sclerosis is atypical in PsA and may be considered, by analogy with ankylosing spondylitis, the final result of repairing mechanisms of the previous erosive changes.

Arthritis, Psoriatic↗

Septic arthritis of the pubic symphysis.

Septic arthritis of the pubic symphysis developed in a previously healthy 13-year-old boy. Blood cultures and the culture of material taken by joint aspiration of the pubic symphysis under radioscopic control yielded Staphilococcus aureus. Early treatment with parenteral antibiotics prevented the development of osteomyelitis of the pubic rami in our patient. Open debridement was not necessary.

Adolescent↗

Vaginal delivery with intrapartum pubic symphysis separation. A case report.

BACKGROUND: Pubic symphysis separation is an uncommon complication of pregnancy. It can occur during the antepartum, intrapartum and postpartum period. CASE: A 29-year-old woman, gravida 2, para 1, at 39 weeks' pregnancy, experienced regular labor pain and suprapubic pain for 3 hours. Her clinical presentation and physical examination led to the diagnosis of intrapartum pubic symphysis separation. Vaginal delivery was chosen because there was no cephalopelvic disproportion. The obstetric outcome was favorable, with a healthy female infant of 3,150 g. The patient underwent conservative management during the postpartum period. She was doing well at the 6-week follow-up. CONCLUSION: In the absence of obstetric indications for cesarean delivery, vaginal delivery can be achieved in cases of intrapartum pubic symphysis separation. Conservative management usually results in complete recovery.

Adult↗

Groin and hip pain due to fractures at or near the pubic symphysis.

Three patients with fractures at or near the pubic symphysis presented with groin pain simulating hip fracture or arthritis. A 71-year-old osteoarthritic woman was treated with a nonsteroidal antiinflammatory drug (NSAID) and exercises for right-sided sciatic pain after a minor fall, but developed left groin pain and tenderness over the pubic symphysis after two days of exercise. She had an impacted fracture of the left pubic symphysis which responded to use of a cane. The second patient was a 90-year-old woman with rheumatoid arthritis (on steroids) who complained of right hip pain after a series of falls in her home. Initially treated with Buck traction for a presumed hip fracture, she was later treated with heat and exercises after negative hip x-rays were obtained. Retrospective analysis of pelvic films and bone scan revealed a right pubic symphysis fracture. The third patient was an 83-year-old rheumatoid arthritic woman with inability to walk secondary to left groin pain. Pubic tomograms revealed disruption of the superior aspect, and bone scan showed increased uptake of the left pubic bone. She was treated with moist heat, rest, and NSAID. Twenty-four cases of os pubis fractures without major trauma or symphysis disruption have been reported. All patients had osteoporosis, and six had rheumatoid arthritis. Our three cases are presented to increase awareness of pubic symphysis fractures as a cause for groin pain, especially in patients with osteoporosis and rheumatoid arthritis.

Aged↗

Osteochondroma of the pubic symphysis associated with sexual disturbance.

Osteochondroma of the pubic symphysis is a rare benign skeletal tumor. We report here a case of an osteochondroma of the pubic symphysis associated with a sexual disturbance, where a computed tomography scan clearly showed a tumor lesion of the pubic symphysis. The case is reported not only because of its rarity but also because it is important that gynecologists should bear this disease in mind, since a patient with this tumor may not visit an orthopedist but a gynecologist.

Adult↗

[A case of pubic symphysis separation].

Perinatal separation of the pubic symphysis is very rare. According to various authors, an incidence of this complication is 1:1700 to 1:30,000 cases. We present a 30-year patient, a Rumanian gypsy (CVI, PVI) in whom pubic symphysis separation was diagnosed on the first day following delivery. A typical therapy, i.e. compression bandage with weights, was introduced. Prophylaxis consists mainly of avoiding excessive exercises and traumas during pregnancy and after delivery.

Adult↗

High accumulations of calcium and phosphorus in women's pubic symphysis.

To elucidate compositional changes of the pubic symphysis (PS) by aging, elements of pubic symphysis (PSs) removed from 26 cadavers were determined by inductively coupled plasma atomic-emission spectrometry. It was found that the relative contents (RCs) of calcium and phosphorus in women's PSs were about three- and five-fold amounts as compared with those in men's PSs, respectively. In contrast, the RCs of sulfur, magnesium, sodium, and iron in women's PSs were somewhat lower than those in men's PSs. The accumulations of calcium (Ca) and phosphorus (P) in women's PSs occurred mainly beyond the age of 70-yr-old, but did not occur in men's PSs.

Adult↗

Osteitis pubis and instability of the pubic symphysis. When nonoperative measures fail.

Seven rugby players with osteitis pubis and vertical instability at the pubic symphysis were treated operatively after nonoperative treatment had failed to improve their symptoms. The vertical instability was diagnosed based on flamingo view radiographs showing greater than 2 mm of vertical displacement. The players had undergone at least 13 months of nonoperative therapy before surgery was considered. Operative treatment consisted of arthrodesis of the pubic symphysis by bone grafting supplemented by a compression plate. At a mean follow-up of 52.4 months, all patients were free of symptoms and flamingo views confirmed successful arthrodesis with no residual instability of the pubic symphysis. Based on our results with this procedure, we believe that arthrodesis of the pubic symphysis has a role in the treatment of osteitis pubis that is recalcitrant to nonoperative treatment. The combination of osteitis pubis and vertical pubis symphyseal instability may be the cause of failure of nonoperative treatment.

Adult↗

Osteitis pubis and assessment of bone marrow edema at the pubic symphysis with MRI in an elite junior male soccer squad.

OBJECTIVES: To assess bone marrow edema at the pubic symphysis with magnetic resonance imaging (MRI), and its relation to training and osteitis pubis in an elite group of junior soccer players. SETTING: Soccer players on scholarship at the Australian Institute of Sport (AIS). PATIENTS: Nineteen players from an elite junior men's soccer squad. INTERVENTION/ASSESSMENT: Serial MRI examinations of the pubic symphysis over a 4-month training and playing period, training session questionnaire, and review of clinical diagnosis, investigations, and records on presentation of athletes with groin pain at the Department of Sports Medicine. MAIN OUTCOME MEASURES: Assessment of bone marrow edema (4-point scale) on MRI scans, review of athlete questionnaires, and review of clinical records. RESULTS: Initial MRI scans showed moderate to severe bone marrow edema at the pubic symphysis in 11 of the 18 asymptomatic players. There was a greatly decreased risk of developing groin pain (osteitis pubis) with more training prior to entry of the AIS soccer program (odds ratio per 4 sessions of training, 0.003). The correlation between initial bone marrow edema grading and pre-AIS training was small. The increase in bone marrow edema grading from baseline over the scans was 0.5 (90% CL, 0.4). CONCLUSIONS: Substantial amounts of bone marrow edema at the pubic symphysis can occur in asymptomatic elite junior soccer players, but it is only weakly related to the development of osteitis pubis. Progressing training loads more slowly in athletes presenting with low current training loads may be a useful strategy for the prevention of osteitis pubis in junior soccer players.

Adolescent↗

Meralgia paresthetica is related to degenerative pubic symphysis.

OBJECTIVE: To investigate the relationship between meralgia paresthetica, a mononeuropathy of the lateral femoral cutaneous nerve that often starts in middle age, and radiological degeneration of the pubic symphysis. METHODS: A case-control study of patients aged 40 years and older with meralgia paresthetica who underwent surgical release of the lateral femoral cutaneous nerve; cases were included only when a pelvic radiograph was available. The control group was from a population study including persons aged 55 years and older and was matched to cases (4 controls per case) for sex and age as far as possible. We checked patient records from general practice to ensure control subjects had no symptoms of meralgia paresthetica during the previous 10 years. Radiological degeneration of the pubic symphysis was defined as present when 2 of 3 independent observers noted degeneration on the radiograph. RESULTS: Mantel-Haenszel procedure (stratified for age group and radiological osteoarthritis of the hip) showed a positive relationship (p = 0.004, OR = 4.38) between radiological degenerative pubic symphysis and meralgia paresthetica. In a separate analysis limited to men we also found this positive relationship. CONCLUSION: This study confirmed a positive relationship between radiological degeneration of the pubic symphysis and meralgia paresthetica.

Female↗

Inhibition by thyrocalcitonin of estrogen-induced bone resorption in the mouse pubic symphysis.

A specific local erosion of the medial edges of the pubic bones is induced by administration of estradiol cyclopentylpropionate (ECP) to thyroparathyroidectomized mice. This paper presents both histochemical and biochemical evidence that porcine thyrocalcitonin (TCT) inhibits this estrogen-mediated resorption of the pubic symphysis. A marked increase in osteoclasts with a resultant increase in demonstrable sites of acid phosphatase (AcP) activity was observed in serial sections of resorbing pubic symphyses from ECP-treated animals. Bioassay of excised pubic symphyses revealed a concomitant increase in AcP activity. When mice were treated with TCT in combination with ECP, a marked decrease in osteoclasts with a resultant decrease in demonstrable sites of AcP activity and inhibition of the resorption process occurred. The mouse pubic symphysis thus appears to offer a model for exploring cellular mechanisms by which TCT regulates bone metabolism.

Acid Phosphatase↗

Locked overlapping dislocation of the pubic symphysis into the obturator foramen: a case report.

A 20-year-old man sustained an overlapping dislocation of the pubic symphysis following a low velocity side-to-side compression injury. Such injuries are rare in the literature. This case, where the pubis was locked into the obturator foramen, may be the first of its kind to be reported. The pubic symphysis was successfully reduced by levering, with difficulty, the locked pubic body out of the left obturator foramen. As the reduction was unstable, the pubic symphysis was fixed with 2 reconstruction plates. The patient was able to mobilise fully after 3 months and returned to work. At 18 months' follow-up he was able to void urine normally after urethral repair.

Adult↗

The effect of relaxin on collagen metabolism in the nonpregnant rat pubic symphysis: the influence of estrogen and progesterone in regulating relaxin activity.

The aim of this study was to examine the effects of relaxin on collagen content, solubility, and composition in the rat pubic symphysis. Nonpregnant, female Sprague-Dawley rats were bilaterally ovariectomized and either unprimed or primed with estrogen or progesterone alone, or a combination of estrogen and progesterone. One week later these animals were given increasing doses of a synthetic human (gene-2) relaxin (0-100 micrograms) before being killed 16 h later. Their pubic symphysial tissues were then removed and analyzed for collagen content and solubility, whereas collagen composition was determined by SDS-PAGE. Relaxin administration significantly increased the length (140 +/- 6%) and weight (170 +/- 9%) of the interpubic fibrocartilage in estrogen-primed rats (n = 15). At the same time, it decreased the total collagen content by 68 +/- 6%, without altering the proportions of collagen types, which were predominantly type I (85%) and type II collagen (15%). Relaxin administered alone reduced the total collagen content by 64 +/- 4% but had no effect on collagen solubility or composition. Progesterone abolished the effects of relaxin in estrogen-primed rats. It is concluded that relaxin has a potent effect on the amount of collagen in the rat pubic symphysis that is enhanced by estrogen and antagonized by progesterone. The changes in the extracellular matrix within the pubic symphysis induced by relaxin may be important in the modifications that this tissue undergoes during pregnancy.

Animals↗

Effects of relaxin, pregnancy and parturition on collagen metabolism in the rat pubic symphysis.

The aim of this study was to examine the changes in collagen metabolism that occur during pregnancy and parturition and upon relaxin administration to the rat pubic symphysial interpubic tissue. Pubic symphyses were collected from non-pregnant, and intact and ovariectomised pregnant Sprague-Dawley rats at days 15, 18 and 21 of pregnancy as well as during and after delivery, and analysed for collagen content and solubility. SDS-PAGE was used to determine collagen composition. During pregnancy and particularly during birth, there was a significant reduction in both the tissue wet (57+/-3%) and dry (43+/-3%) weight (n=7), which coincided with a significant increase in water content (to 80%) and was attributed to a significant (P<0.05) reduction in overall tissue collagen content (by 47+/-2%). This resulted in both soluble (10%) and insoluble (90%) collagen levels being reduced, but gel electrophoresis demonstrated the presence of types I, II and V collagen in all samples. Western blot analysis confirmed the presence of type II collagen throughout pregnancy, confirming that the rat pubic symphysis remained a fibrocartilaginous tissue throughout gestation. In the absence of the ovaries and hence relaxin, tissue collagen content and solubility were not significantly different from control measurements. However, tissues of ovariectomised animals treated with oestrogen and progesterone (pellets) and relaxin (injection) contained collagen levels that mimicked those of late pregnancy and parturition. These results suggest that relaxin plays an important role in regulating collagen catabolism during gestation in the rat.

Analysis of Variance↗

Pubic symphysis repair strength in simulated bladder exstrophy using a sheep model.

OBJECTIVES: To investigate the mechanical strength of various pubic symphysis suture material in a simulated animal model of neonatal bladder exstrophy. METHODS: Neonatal lamb pelves, which are the approximate size of neonatal human pelves, were used. Twenty-four neonatal lamb pelves were divided into four equal groups. A midline symphysotomy was made through the cartilaginous pubic symphysis in three groups and repaired using two figure-of-eight sutures (size 0) placed through the cartilaginous pubis using polypropylene, braided polyester, or polyglactin. The fourth group served as the control. The pelves were then tested to ultimate load in pure tension at a strain rate of 0.25 mm/s until failure. RESULTS: There was a highly significant difference between the intact specimens and the repaired specimens (P = 0.0008). For the repaired specimens, there was a significant difference in the ultimate load normalized by pubic height between those repaired with polypropylene and polyglactin (P = 0.025), but not for those repaired with polypropylene and braided polyester (P = 0.11) or braided polyester and polyglactin (P = 0.11). CONCLUSIONS: Braided resorbable sutures are recommended for pubic symphysis repair, because they have a lower tendency to cut out of the cartilage.

Animals↗