Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “PRISCOLINE”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

[Pharmaco-angiography with Priscolin in progressive scleroderma (author's transl)].

The morphological and haemodynamic findings in the vessels of the forearm and hand in 21 patients with progressive scleroderma are described. In these patients, brachial arteriograms have been carried out before instituting fibrinolytic therapy. Injections were carried out before and after intra-arterial Priscolin and the results were compared. Obliterative changes in the digital arteries are already present during the oedematous stage. Between the oedematous and advanced stages, there are vascular changes of progressive severity. In the sclerotic stage, the changes may be less marked, but more often consist of advanced obliterative vascular disease; this cannot be distinguished from the atrophic stage. The haemodynamics of the digital arteries can be influenced by Priscolin and this provides some information regarding the arterial side of the dermal micro-circulation. Even during the oedematous stage one can observe contrast stasis which is irreversible and not influenced by Priscolin.

Adolescent↗

Priscoline and epinephrine in selective pancreatic angiography: a comparison study using high pressure injection, Valsalva maneuver and geometric magnification.

The value of selective, high injection rate, pancreatic pharmacoangiography was assessed in 114 patients. Opacification of the pancreas was graded on a 0-4+ scale. Selective injection of gastroduodenal and small pancreatic arteries gave the best results, 3.7+. Celiac injection rating without drugs was 0.9+, with epinephrine 2.2+, and with Priscoline 2.7+. Average ratings of hepatic artery injections were 2.6+ with epinephrine and 3.0+ with Priscoline; splenic artery injections were 2.5+ and 3.5+, respectively. Although superselective injection was possible in only 50% of the cases, addition of epinephrine and Priscoline resulted in an average grading of 3.4+ (yielding a preoperative diagnostic accuracy of 94%).

Adenocarcinoma↗

Priscoline-augmented hepatic angiography.

Tolazoline hydrochloride (Priscoline) is a useful adjunct to hepatic angiography in the evaluation of space-occupying lesions. It was of definite value in 8 of 26 studies, either in facillitating the diagnosis or in evaluating the extent of disease. The mechanism of enhanced visualization is presumably related to its vasodilatory effect on the small blood vessels of the liver. Priscoline deserves further evaluation in the following situations: (a) a negative hepatic angiogram in the face of positive clinical findings or radionuclide images; (b) suspicious but not definitive findings on conventional hepatic angiography; and (c) assessment of the full extent of disease.

Adult↗

Improved musculoskeletal angiography with large volume contrast injection and priscoline.

Previously published studies of musculoskeletal angiography have not discussed the technical details of how the angiograms were performed. In the present report, two series of 57 consecutive angiograms were compared with respect to radiologic quality and clinical usefulness. The second series differed from the first in closer consultation between angiographer and orthopaedist and the use of intra-arterial Priscoline, large volume contrast injection, multiple views, geometric magnification, and photographic subtraction. These efforts were rewarded by greater vascular detail and better delineation of tumors on the angiograms. Especially with respect to soft tissue lesions, the surgeon found the studies more accurate and more useful in planning surgical management.

Angiography↗