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At least 19 recordsLinked to original sources

Evaluation of neurological examination of sheep.

One hundred clinically negative Merino sheep were examined neurologically in an attempt to establish normal responses. Dependable results were obtained regarding eye muscle integrity, corneal sensitivity, the optic papilla and righting reflexes and to some extent the knee jerk reflex. The elicitation of other reflexes was inconsistent and unreliable except the placing reflex as shown by raising and lowering the forequarters.

Animals

[Developmental neurological examinations in preparatory school children (author's transl)].

302 primarily healthy preparatory school children aged from 4-6 years were examined neurologically, using a slightly modified Touwen-Prechtl examination scheme. It was possible to make statistically confirmed statements on the individual tests of neurological function for a German kindergarten population. To develop a short (screening) test representative of the entire nervous system would be very difficult indeed. We hope, however, by means of rational data reduction, to be able to find a compromise between the complexity of the nervous system and the necessities of practice.

Age Factors

Training examiners to administer a quantitative neurological examination for a multicenter clinical trial.

A battery of quantitative neurological tests was used in a multicenter clinical trial to compare ACTH with placebo for the treatment of patients with multiple sclerosis in acute exacerbation. Since the battery of tests was administered in ten centers by physical therapists, it was critical that the examiners were well trained and remained so. Results of experiments showed that physical therapists could be successfully trained to administer the tests in a uniform fashion and remained trained for three years, the duration of the clinical trial. The fact that physical therapists are not taught tell-tale side effects of a treatment, and hence do not perceive these as do the physician examiners, introduces another level of objectivity into neurological clinical trials.

Activities of Daily Living

The reliability and diagnostic validity of the physical and neurological examination for soft signs (PANESS).

Twenty-one children, mean age of 8 years, were each examined on separate occasions by two pediatric residents, blind to diagnosis, using the neurological examination (PANESS) included in the group of instruments recommended by the National Institute of Mental Health for psychotropic drug studies in children. Half the children were hyperactive/aggressive, one quarter were normal, and one quarter had histories or signs strongly presumptive of brain damage. Many of the signs, though reliable, did not occur in the majority of children. Examiners did achieve a high level of agreement about global neurological status. It was concluded that the neurological examination probably contains a substantial number of non-contributory items and should be regarded as experimental rather than definitive.

Brain Damage, Chronic

The neurologic examination in patients with central nervous system trauma.

The neurological assessment of the head injured patient must be integrated into the emergency management and daily care of the patient. Neurosurgical nurses are in the best position to perform serial neurologic examinations and assess changes in the patient's clinical picture. If this added responsibility is assumed, neurosurgical nurses must take an active role in improving assessment skills. The improved assessment of the head injured patient will result in early intervention in the patient's course to avert potential problems, thus resulting in improved morbidity and eventual outcome. As neurosurgical nurses expand their roles in nursing, improved patient assessments are mandatory to deliver optimal patient care.

Humans

Comparison of the averaged evoked cisterna cerebellomedullaris potential, cortical potential, and neurologic examination in the diagnosis of spinal cord injury of the dog.

Average cerebrocortical potentials (ECP) and cisterna cerebellomedullaris potentials (ECMP), evoked by ulnar and sciatic nerve stimulation, were compared with neurologic examination to evaluate their accuracy in the diagnosis of the degree of experimental spinal injury in 24 Beagles. The dogs were divided into 2 equal groups. Various impact forces were applied to the spinal cord at L1 of 1 group of dogs and various degrees of compression forces were applied to the spinal cord at L1 of the other group of dogs. The degrees of functional loss in both groups of dogs extended from mild to complete. The dogs were untreated and monitored for 30 days after injury. A short-acting barbiturate was compared with a long-acting barbiturate as the means of anesthesia; both were found to permit similar production of ECP and ECMP. The ECMP was found to be a more sensitive, more easily interpreted, and more consistent means of evaluating the degree of spinal injury than the ECP or the neurologic examination.

Anesthesia

Serial neurologic examination of hyperactive children.

Forty-four of 102 children undergoing pharmacologic treatment of hyperactivity received serial neurologic examinations on five separate occasions. The responses to three of the "soft" neurologic signs administered were analyzed: heel gait, toe gait, and diadochokinesis. A high degree of variability of response within individuals was documented. There was no evidence of interaction between treatment and the subjects' responses. The degree of variability was such that to have used these data as measures of "improvement" (i.e., drug effect) would have been misleading. The value of these signs for purposes of diagnosis or assessment of therapy is doubtful.

Child

Spontaneous labour and elective induction--a prospective randomized study. Behavioural assessment and neurological examination in the newborn period.

The effect of induction of labour on the foetus and the newborn was investigated in a prospective randomized study. 41 neonates were studied after induction at full term by amniotomy and intravenous oxytocin infusion. The infusion rate was regulated by the intraamniotic pressure using the Cardiff infusion pump system. 39 neonates served as controls where the labour started spontaneously followed by amniotomy. In both groups foetal heart rate monitoring intraamniotic pressure recordings were performed. There were no differences in Apgar score and pH in cord blood between the groups. The newborns were evaluated the first and the fifth day of life with the Brazelton Neonatal Behavioral Assessment Scale and with a modified Prechtl neurological examination. There were no differences in behaviour and neurological state between the two groups. However, within the groups there were significant differences between the first and the fifth day concerning both neonatal behaviour and neurological state.

Anesthesia, Obstetrical

Patterns of breath intervals during non-nutritive sucking in full-term and 'at risk' preterm infants with normal neurological examinations.

The interaction between respiration and non-nutritive sucking rhythms was investigated in 12 sleeping, normal full-term, newborn infants and in 14 preterm infants were were examined repeatedly at 34, 40 and 46 wk of conceptional age. Full-term infants showed a shortening of breath intervals in the middle of sucking bursts and a lengthening of the breath interval spanning the end of sucking bursts. The differences were more marked in females than males. A rhythm interaction between sucking and respiration was also observed in preterm infants as young as 34 wk of conceptional age. Clinical neurological examinations did not discriminate between preterm infants above and below a median score for optimal obstetric conditions, but the interaction between breathing and sucking rhythms made such discrimination, most clearly in females. Preterm infants with lower optimal obstetric scores showed less change of breath durations during sucking than preterms with higher scores. It was concluded that interaction of concurrent motor rhythms may be a sensitive index of central nervous system integrity in newborn infants, even when there are no clinical neurological signs of nervous system dysfunction.

Circadian Rhythm