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Results for “National Association for Biomedical Research”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

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At least 19 recordsLinked to original sources
PubMed1996

Animal care and use: an issue now and in the future.

Animal rights proponents equate human and animal rights or capacity to suffer pain. Animal welfare is a philosophy that centers on animal well-being, a stewardship role that producers view as affecting profitability but the general public may view as having additional components. The agenda of some animal rights proponents may be positioned under the guise of animal welfare to gain acceptability for portions of their work. Currently, guidelines and accreditation programs targeted at ensuring proper animal care and use increasingly include agricultural animals. Also, public initiatives such as the Massachusetts ballot initiative to curtail animal agriculture and the Physicians Committee for Responsible Medicine's attempts to curtail the use of milk and meat in human diets were defeated by educating the general public. Various organizations have been developed to address animal care and use issues. The Animal Industry Foundation is a broad-based agricultural organization addressing animal rights issues. National biomedical organizations, the Foundation of Biomedical Research and the National Association for Biomedical Research, address education and governmental animal rights issues. State-level coalitions, such as those recently organized in Missouri, of agricultural organizations, academic research units, biomedical institutions, and agribusiness or consumer products companies offer great promise of educating others on animals rights and welfare issues. Animal scientists need to educate themselves on these issues, participate in their own institutional Animal Care and Use Committees, and help to educate the general public through organizations and programs at the local, state, and national level.

Animal Husbandry↗
PubMed1988

Animals in research.

Explore the source record for details and available documents.

American Medical Association↗
PubMed2000

Development of a pollution prevention and energy efficiency clearinghouse for biomedical research facilities.

This is the report of the National Association of Physicians for the Environment Committee on Development of a Pollution Prevention and Energy Efficiency Clearinghouse for Biomedical Research Facilities from the Leadership Conference on Biomedical Research and the Environment held at the National Institutes of Health in Bethesda, Maryland, on 1--2 November 1999. A major goal of the conference was the establishment of a World Wide Web-based clearinghouse, which would lend tremendous resources to the biomedical research community by providing access to a database of peer-reviewed articles and references dealing with a host of aspects of biomedical research relating to energy efficiency, pollution prevention, and waste reduction. A temporary website has been established with the assistance of the U.S. Environmental Protection Agency (EPA) Regions III and IV, where a pilot site provides access to the EPA's existing databases on these topics. A system of peer review for articles and promising techniques still must be developed, but a glimpse of topics and search engines is available for comment and review on the EPA Region IV-supported website (http://wrrc.p2pays.org/).

Biomedical Technology↗
PubMed2000

Minimization and management of wastes from biomedical research.

Several committees were established by the National Association of Physicians for the Environment to investigate and report on various topics at the National Leadership Conference on Biomedical Research and the Environment held at the 1--2 November 1999 at the National Institutes of Health in Bethesda, Maryland. This is the report of the Committee on Minimization and Management of Wastes from Biomedical Research. Biomedical research facilities contribute a small fraction of the total amount of wastes generated in the United States, and the rate of generation appears to be decreasing. Significant reductions in generation of hazardous, radioactive, and mixed wastes have recently been reported, even at facilities with rapidly expanding research programs. Changes in the focus of research, improvements in laboratory techniques, and greater emphasis on waste minimization (volume and toxicity reduction) explain the declining trend in generation. The potential for uncontrolled releases of wastes from biomedical research facilities and adverse impacts on the general environment from these wastes appears to be low. Wastes are subject to numerous regulatory requirements and are contained and managed in a manner protective of the environment. Most biohazardous agents, chemicals, and radionuclides that find significant use in research are not likely to be persistent, bioaccumulative, or toxic if they are released. Today, the primary motivations for the ongoing efforts by facilities to improve minimization and management of wastes are regulatory compliance and avoidance of the high disposal costs and liabilities associated with generation of regulated wastes. The committee concluded that there was no evidence suggesting that the anticipated increases in biomedical research will significantly increase generation of hazardous wastes or have adverse impacts on the general environment. This conclusion assumes the positive, countervailing trends of enhanced pollution prevention efforts by facilities and reductions in waste generation resulting from improvements in research methods will continue.

Biomedical Technology↗
PubMed1982

Adequate health research funding: a justifiable imperative.

The position paper that follows was developed by an ad hoc committee comprised of representatives of national organizations interested in biomedical and behavioral research including the Association of American Medical Colleges, the Association of American Universities, the Delegation for Basic Biomedical Research, and the National Committee for Medical Research and Education. The development of this document represented a unique attempt to reach a consensus among the diverse segments of the research community on the level of funding necessary to preserve the integrity of the health research enterprise. This paper was subsequently endorsed by 58 major organizations with a commitment to maintaining a strong national research program. The AFCR Public Policy Committee endorsed this position paper on July 10, 1982. It is worthy of note that although recent trends in health research funding are cause for concern, this situation will worsen in the future because of the recent passage of the Small Business Innovation Development Act. This bill will require all federal agencies, including the NIH, to "set-aside" 1.25% of their R&D budgets for allocation to small businesses. The FY 1983 projections in this position paper do not include estimates of the impact of this recent legislation.

Health Services Research↗
PubMed2000

Biomedical research leaders: report on needs, opportunities, difficulties, education and training, and evaluation.

The National Association of Physicians for the Environment (NAPE) has assumed a leadership role in protecting environmental health in recent years. The Committee of Biomedical Research Leaders was convened at the recent NAPE Leadership Conference: Biomedical Research and the Environment held on 1--2 November 1999, at the National Institutes of Health, Bethesda, Maryland. This report summarizes the discussion of the committee and its recommendations. The charge to the committee was to raise and address issues that will promote and sustain environmental health, safety, and energy efficiency within the biomedical community. Leaders from every important research sector (industry laboratories, academic health centers and institutes, hospitals and care facilities, Federal laboratories, and community-based research facilities) were gathered in this committee to discuss issues relevant to promoting environmental health. The conference and this report focus on the themes of environmental stewardship, sustainable development and "best greening practices." Environmental stewardship, an emerging theme within and outside the biomedical community, symbolizes the effort to provide an integrated, synthesized, and concerted effort to protect the health of the environment in both the present and the future. The primary goal established by the committee is to promote environmentally responsible leadership in the biomedical research community. Key outcomes of the committee's discussion and deliberation were a) the need for a central organization to evaluate, promote, and oversee efforts in environmental stewardship; and b) immediate need to facilitate efficient information transfer relevant to protecting the global environment through a database/clearinghouse. Means to fulfill these needs are discussed in this report.

Biomedical Technology↗
PubMed1993

Two alternative forms of cDNA encoding CD34.

By expression cloning using FACS, we have isolated cDNA clones encoding human CD34 from a megakaryoblastoid cell line. The predicted amino acid sequence of CD34 revealed the type I transmembrane protein consisted of a leader peptide (31 residues), an extracellular domain (258 residues), a transmembrane domain (23 residues) and a cytoplasmic domain of 73 residues. In addition, a second form of cDNA that has 194 bp insertion in the cytoplasmic region was isolated. The analysis of genomic DNA showed that this sequence is inserted between the predicted transmembrane and cytoplasmic exons due to an alternative usage of an imperfect 5' splice acceptor site in the 5' flanking region of the cytoplasmic exon. The insertion brings a stop codon so that the protein encoded by this type of mRNA has only 16 residues in the cytoplasmic domain. This truncated form of CD34 molecule can be expressed on the cell surface, and its expression seems to change in association with cell differentiation. A search of the National Biomedical Research Foundation Protein Sequence Database (NBRF) with the Predicted amino acid sequence of CD34 did not reveal homology to any known protein. Thus, the CD34 molecule represents a novel type of cell surface molecule that may have a role in early differentiation process of hematopoietic stem cells.

Amino Acid Sequence↗