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At least 19 recordsLinked to original sources
PubMed1976

Some adrenomimetic drugs affecting lipolysis in human adipose tissue in vitro.

In human adipose tissue in vitro, dose-response curves were followed for different adrenomimetics releasing free fatty acids and glycerol into an albumin-containing medium. Phenylephrine, salbutamol and t-butyl-norsynephrine produced lipolytic actions whose maximum did not exceed 20% of the maximal isoproterenol lipolysis. Phentolamine (1 x 10(-5) M) did not potentiate the effect of any of these drugs. When using salbutamol or t-butyl-norsynephrine for antagonizing isoproterenol actions, typical antagonism was found. The parallel shift of the isoproterenol curves showed pA2 values 5.8 for salbutamol and 5.7 for t-butyl-norsynephrine. Comparison of human and rat adipose tissue reactivity shows identical affinities of the drugs studied in both tissues, but related to isoproterenol, diminished intrinsic activities of salbutamol and t-butyl-norsynephrine in human adipose tissue.

Adipose Tissue↗
PubMed1964

I-OCTOPAMINE IN CITRUS: ISOLATION AND IDENTIFICATION.

l-Octopamine, [l-p-hydroxy-alpha-(aminomethyl)benzyl alcohol], has been isolated and identified from extracts of juice and leaves of the Meyer lemon. Identification was by chromatography, optical rotation, ultraviolet absorption curves, fluorescence spectra, and infrared spectroscopy. l-Octopamine has not previously been isolated and identified from plants.

Chromatography↗