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At least 19 recordsLinked to original sources
PubMed1976

Solitary intraosseous neurilemmoma of the tibia: review of intraosseous neurilemmoma and neurofibroma.

This is a case report of a 59-year-old woman with a neurilemmoma involving the tibia, a site not previously reported for this tumor. Neurilemmoma, a benign neoplasm which rarely involves bone, arises from the Schwann cells in the nerve sheath. It is a distinct pathological entity separate from solitary neurofibroma, and arises from the connective tissue coats of nerves, but which also involves bone. The incidence of the 2 types of nerve sheath tumors is obscured by the tendency of some authors to use the terms interchangeably. Forty-eight cases of true intraosseous neurilemmoma have been reported in the literature. Of 18 cases of solitary intraosseous neurofibroma primary in bone, all were in the jaw and 6 were malignant. The diagnosis of intraosseous neurilemmoma may be missed because of its rarity and roentgenologic appearance of cystic bone disease which is not distinctive except that it resembles other commonly encountered bone lesions. A positive diagnosis is based only on the microscopic pathology. Complete local resection generally produces an excellent result without recurrence.

Bone Neoplasms↗
PubMed2005

[Multiple synchronous intrathoracic neurilemmomas who had a past history of neurilemmoma on the abdominal wall; report of a case].

A 66-year-old female, who had received a surgery of the neurilemmoma on the abdominal wall 6 years ago, was referred to our hospital because of a chest X-ray abnormality. Chest computed tomography (CT) revealed 3 tumors in the left chest wall. One tumor arised from the 7th intercostal nerve and 2 tumors from 8th nerve. These tumors were surgically removed by video-assisted thoracic surgery. These tumors are histopathologically diagnosed as neurilemmoma and have the same characteristics with previously resected abdominal wall tumor.

Abdominal Wall↗
PubMed2006

[Neurilemmoma of the head and neck--report of 3 cases].

BACKGROUND: Neurilemmoma are benign tumors of the nerve-sheath, also known as schwannoma. Beside intracranial manifestation, neurilemmoma are found at other peripheral nerves of the head and neck. CASE REPORT: We present three cases of patients with seldom manifestation of neurilemmoma of the supraglottis, the retropharyngeal space and a neurilemmoma of the hypoglossal nerve. The histological examination showed two types of Antoni-A-neurilemmoma, whereas one tumor was found with mixed type A and B-neurilemmoma. CONCLUSION: Although extracranial neurilemmoma of retropharygeal space, neck or supraglottic larynx are rare tumors, neurilemmoma should be involved in differential diagnosis of tumors in these areas. The therapy of choice consists of complete surgical removal and histological examination.

Airway Obstruction↗
PubMed2004

Extraaxial neurofibromas versus neurilemmomas: discrimination with MRI.

OBJECTIVE: The purpose of our study was to evaluate whether MRI can discriminate between extraaxial neurofibromas and neurilemmomas. MATERIALS AND METHODS: MR images of 52 patients with a pathologically proven extraaxial neurofibroma or neurilemmoma were retrospectively reviewed by observers who were unaware of the surgical results, regarding the presence or absence of individual imaging criteria. MRI findings in 12 patients with a localized neurofibroma and 40 patients with a neurilemmoma were compared using the chi-square test or Fisher's exact test. RESULTS: MRI findings suggestive of neurofibroma (p < 0.05) were a target sign on T2-weighted images (58% in neurofibromas vs 15% in neurilemmomas), central enhancement (75% vs 8%), and a combination of both findings (63% vs 3%). MRI findings suggestive of a neurilemmoma (p < 0.05) were a fascicular appearance on T2-weighted images (25% vs 63%), a thin hyperintense rim on T2-weighted images (8% vs 58%), a combination of both findings (8% vs 48%), and diffuse enhancement (13% vs 67%). No significant difference was seen between neurofibromas and neurilemmomas for a centrally entering and exiting nerve (42% in neurofibromas vs 23% in neurilemmomas), a peripherally entering and exiting nerve (58% vs 77%), a cystic area (38% vs 64%), a low-signal margin (100% vs 100%), peripheral enhancement (13% vs 26%), or a target sign on contrast-enhanced images (11% vs 31%). CONCLUSION: MRI shows features helpful for differentiating extraaxial neurofibromas from neurilemmomas; however, no single finding or combination of findings allows definitive differentiation.

Adolescent↗
PubMed2002

Pneumosinus dilatans associated with orbital neurilemmoma.

BACKGROUND: [corrected] Pneumosinus dilatans (PSD) is a rare condition. It has been reported in association with spheno-orbital meningioma, optic nerve sheath meningioma, orbital fibro-osseous diseases and intracranial meningioma, but never with orbital neurilemmoma. We report 4 cases of orbital neurilemmomas in association with PSD, and stress the importance of PSD in cases of orbital neurilemmomas. METHODS: We reviewed the hospital chart, and found 324 orbital tumors were found from 1974 to 1996. Eight consecutive cases of pathology-proven primary orbital neurilemmoma were studied. Clinical features, es pecially computed tomography (CT) scan, were completely reviewed to find the co-existence of orbital neurilemmoma and pneumosinus dilatans. RESULTS: Four cases (50%) among 8 cases of pathology-proven orbital neurilemmomas were found to have pneumosinus dilatans in their CT scan. All these four cases were extraconal tumors. Representative CT scan showed enlarged, aerated sinus with thinning of the affected sinus walls. Ethmoidal, frontal and maxillary sinuses were the most frequently affected. CONCLUSIONS: Pneumosinus dilatans is commonly associated with primary orbital neurilemmoma.

Adult↗
PubMed1989

[Neurilemmoma of the soft tissues: an analysis of 1,271 tumors in an attempt at subtyping].

A total of 1,271 neurilemmoma occurring in 1,202 Japanese patients were reviewed, classifying into seven categories: ordinary (932), degenerated (238), cellular (19), plexiform (35), pigmented (2), myxomatous (16) and organoid (30) types. The present clinicopathologic study revealed that some of these types possessed distinguishing characteristics. Tumors of both degenerated and cellular types usually occurred in the deep soft tissues and were larger in size than tumors of ordinary type. Degenerated type tumors had longer duration before surgery than other type tumors in average, and one of the cellular type tumors had histologically been diagnosed as malignant. Plexiform neurilemmoma often developed in the superficial tissues, such as the skin and the subcutaneous tissue, of younger patients with longer durations and histologically exhibited intraneural growths. Organoid tumors consisting mainly of multiple complexes resembling the touch corpuscles were characterized by the younger average age of patients and by the site preference of the head and neck. A few cases of this type were connected with nerve trunks and suffered pain. Myxomatous neurilemmoma reminiscent of nerve sheath myxoma occurred in deep soft tissues of the extremities and showed a predilection for females (M:F = 4:12). Six of the seven patients with myxomatous neurilemmoma with available informations gave a distinct relation with nerve trunks and 11 of the 12 patients complained of pain. Seventy-two of the 1,202 patients had multiple neurilemmoma, in which 14 had clinically been diagnosed as von Recklinghausen's neurofibromatosis. While recurrences were evident in nine patients with neurilemmoma, including six with ordinary type tumor and three with degenerated neurilemmoma, no patients had died of the tumor.

Adolescent↗
PubMed1998

[Histopathologic study on intratemporal minimal facial nerve neurilemmomas].

OBJECTIVE: To explore the original location and pathologic behavior of facial nerve neurilemmomas. METHODS: Human temporal bone slides from 815(1,526 ears) were histopathologically observed under light microscope. RESULTS: Seventeen(1.84%) undiagnosed intratemporal facial nerve neurilemmoma with morphologic indications of Antoni type A were found. According to pathologic features, the intratemporal facial nerve neurilemmomas were classified as ingrowing facial nerve neurilemmomas (4 ears) which originated from the center of facial nerve, and outgrowing facial nerve neurilemmomas (13 ears) which originated from the perineurium at dehiscence of the facial nerve canal. Of the 17 tumors, two originated from the labyrinthine segment, twelve from the tympanic segment, one from second turn and two from vertical segment. CONCLUSION: It is of important pathologic and clinical significance to classify the intratemporal facial nerve neurilemmomas into outgrowing and ingrowing types.

Adult↗
PubMed1993

Localized multiple neurilemmomas of the lower extremity.

A neurilemmoma usually presents as a solitary subcutaneous tumor adherent to a peripheral nerve. Multiple localized neurilemmomas may occur as an isolated cutaneous finding or as part of the syndrome of neurilemmomatosis. We report a case of multiple neurilemmomas appearing on an extremity after trauma. The multiplicity and localization of the tumors are rare and illustrate that neurilemmomas are not invariably solitary tumors and that their distribution can be regional. We review the previously reported cases of multiple neurilemmomas and review the characteristics that help the clinician to differentiate between multiple localized neurilemmomas and neurilemmomatosis.

Ankle↗
PubMed2004

Clinical pathology and therapeutic results of neurilemmoma in the upper extremity.

PURPOSE: To evaluate the clinical pathology and postoperative outcomes of patients with neurilemmoma in the upper extremity who underwent tumour enucleation, and the correlation factors for neurological deficits apart from enucleation of nerve fascicles. METHODS: Magnetic resonance imaging was used to evaluate the state of lesions of the patients with upper-extremity neurilemmoma who underwent tumour enucleation. To find out the correlation factors for neurological deficits, the patients were then divided into 2 groups based on their recovery period-group A (shorter than 6 months) and group B (at 6 months or longer). Duration of the illness, the affected nerve, and the size and histological type of the tumour were then compared between the 2 groups. RESULTS: Of the 20 patients who underwent tumour enucleation for neurilemmoma in the upper extremity, 19 had a single nerve affected and one had multiple lesions involving two nerves. The tumours in 6 patients were of Antoni A type histology and in the remaining 14 patients were of a mixed type. Antoni B type alone was not observed. 15 patients showed postoperative neurological deficits. No neurological deficits were observed in 5 patients. Neurological deficits were fully recovered in all patients except the one with a lesion in the digital nerve. Apart from enucleation of nerve fascicles, the period required for the recovery of neurological deficits was correlated to the duration of the illness (p=0.04) and the histological type of the tumour (p=0.03). CONCLUSION: Most of the patients with neurilemmoma (95%) had a single nerve affected. A majority of patients (70%) had the mixed type of Antoni A and Antoni B histology; Antoni B type alone was not observed. Neurological deficits were observed in 75% of patients. In patients with neurilemmoma developing in the upper extremity, the period required for recovery from postoperative neurological deficits was short when the duration of illness was short and when Antoni A type histology was present.

Adolescent↗
PubMed2005

Intraosseous neurilemmoma of L2 vertebra--a case report.

Intraosseous neurilemmoma (schwannoma) is a rare bone tumor with incidence less than 0.2% of all primary bone tumors. It is a benign neoplasm arising from the schwann cells of the nerve sheath. When they occur, they are usually found in the mandible. This paper reports an unusual occurrence of intraosseous neurilemmoma in L2 vertebral body. This patient presented with complaints of backache and progressively increasing weakness in both lower limbs. Roetengenograms showed an osteolytic lesion of L2 vertebra localized in the left half of the body and pedicle. Computed tomograph revealed a large soft tissue component of the tumor mass with thecal sac compression. A computed tomograph assisted needle biopsy revealed the tumor to be neurilemmoma. Subsequently, during decompression, it was possible to shell out tumor from surrounding tissues. Remaining tumor was curettedfrom bone and the cavity packed with autograft. The recovery was uneventful with incorporation of graft. The aim of this article is to highlight intraosseous neurilemmoma as a possible differential diagnosis in bony tumors. Intraosseous neurilemmoma of lumbar vertebrae is an extremely rare occurrence and till date only four cases are reported in English literature.

Adult↗
PubMed2006

[Cervical sympathetic chain neurilemmoma--a case report].

INTRODUCTION: Neurilemmoma is benign, slowly growing tumour that arise from nerves. Cervical sympathetic chain neurilemmoma is rare. The majority of neurilemmomas are asymptomatic at the time of presentation. The incidence of Horner's syndrome before excision has been reported only once. Surgical resection almost leaves the patient with a Horner's syndrome. MATERIAL AND METHODS: A 28 years old woman was admitted to Otolaryngology Department with left side neck mass. The tumor was first noticed 6 month later, and it was slowly growing. It was completely asymptomatic. She underwent excision of the tumor through an incision parallel with the anterior border of the strenomastoid muscle. RESULTS: Histology showed the tumour to be a neurilemmoma arising within the cervical sympathetic chain. During postoperative period in 2 day we observed a left side Horner's syndrome, completely asymptomatic. CONCLUSIONS: Neurilemmomas very rarely arise from the cervical sympathetic chain. They usually present as asymptomatic neck mass. The only complication encountered after surgery is Horner's syndrome, which required no treatment.

Adult↗
PubMed1993

Neurilemmoma of the head and neck.

The neurilemmoma is an uncommon tumour of the oral cavity. In this present series of soft tissue neurilemmomas the majority occurred within or around the mouth. Initially these were provisionally diagnosed on clinical appearances and behaviour as commoner benign lesions, including the fibro-epithelial polyp, mucocele and papilloma. On sampling they were found to have the histological features of a neurilemmoma. This suggests that the solitary neurilemmoma occurs more frequently than previously reported and should be included in the differential diagnosis of these more frequent benign lesions occurring in and around the mouth.

Adolescent↗
PubMedDate not supplied

Neurilemmomas of the paranasal sinuses.

Within the head and neck region, neurilemmomas are rarely found in the nasal cavity or paranasal sinuses. A 70-year-old man presented with complaints of left-sided epiphora, rhinorrhea, epistaxis, and transient diplopia. Nasal endoscopy showed a large necrotic mass filling the left middle meatus. A computed tomography scan showed a large left ethmoid mass, with erosion of the medial wall of the orbit and the anterior cranial base. Multiple biopsies were nondiagnostic. Complete excision of the tumor was performed with endoscopic techniques. Small dural defects were repaired with a middle turbinate mucosal flap. Postoperatively, the patient was treated with nasal packing and a lumbar spinal drain. Final pathology showed a benign neurilemmoma. There has been no evidence of recurrence or cerebrospinal fluid leakage in follow-up. A review of the literature shows a similar presentation of patients with neurilemmomas of the paranasal sinuses. Bony destruction and intracranial extension is viewed. Lack of encapsulation and locally destructive growth in an otherwise histologically typical neurilemmoma should not suggest malignant potential. Many benign tumors of the paranasal sinuses with bone destruction may be removed by using endoscopic techniques.

Aged↗
PubMedDate not supplied

Clinical and histopathological features of a large parapharyngeal neurilemmoma located at the base of the tongue.

Neurilemmomas of the tongue have only been sporadically reported in the literature. Vague symptoms and limited knowledge of this kind of tumor may result in long delays before diagnosis and treatment. The rarity of the lesion in this area is the main reason why we report this case of neurilemmoma. After observation of a mass in the tongue, magnetic resonance imaging showed a large tumor with central necrosis localized to the base of the tongue. Needle electromyography disclosed no nerve lesion. Fine-needle aspiration cytology was negative, whereas biopsy revealed a neurilemmoma. The tumor was surgically removed, and histopathology, including immunohistochemistry, of the resected specimen disclosed the typical neurilemmoma. The postoperative course was uneventful.

Adult↗
PubMed1979

Combined neurilemmoma and angioma. Tumor of ectomesenchyme and a source of bleeding.

Eight cases are described of intracranial and peripheral neoplasms composed of mixed neurilemmoma and hemangioma. It is proposed that ectomesenchyme can differentiate into neurilemmoma and angioma. The latter may be related to recently described angiogenetic factors, or to developmental factors as in rare cases of arterial angiomas. The angiomatous part may be common, but has often been overlooked. The presence of abnormal vessels, whether in kind or in number, helps explain various biological features of neurilemmoma. These vessels frequently bleed within the tumor, which results in the characteristic hemosiderin-laden macrophages. Bleeding may also occur into the cerebrospinal fluid (CSF) to create xanthochromia. The frequent increase in CSF protein in cases of neurilemmoma is attributed to transudation of serum from abnormal vessels. Less commonly, bleeding may be sufficient to cause subarachnoid hemorrhage. The dense collagen usually associated with these angiomas accounts for the relative infrequence of major hemorrhages.

Aged↗