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8 recordsLinked to original sources
PubMedDate not supplied

Quantitative electrocardiography during extended space flight.

To assess the effects of prolonged space flight on the electrophysiological properties of the heart, vectorcardiograms (VCG) were obtained on the Skylab crews at regular intervals during flight and the pre- and postflight periods. The VCG signals were telemetered from Skylab and analyzed by digital computer. Conventional 12-lead electrocardiograms were derived from the VCG signals by a lead transformation program. Standardized exercise loads were incorporated into the experiment protocol to increase the sensitivity of the VCG for effects of deconditioning and to detect susceptibility for arrhythmias. In Skylab II, 24 preflight, 21 inflight, and 19 postflight experiments were analyzed. Statistically significant inflight changes observed in two or more crew members included: decreased resting heart rate, increased QRS duration, anterior shift QRS vector, increased QRS vector magnitude, anterior shift T vector, and increased T vector magnitude. One astronaut had occasional premature ventricular contractions (PVC) during the pre- and postflight phases. He had a single episode of multiple PVC's during heavy-load exercise testing in flight. A second astronaut had no arrhythmia during pre- or inflight testing. On postflight day 21 he had multiple PVC's and salvos of ectopic ventricular beats. He has had no recurrence of the arrhythmia. With the exception of the cardiac arrhythmias, no deleterious electrophysiological changes were observed during Skylab II.

Arrhythmias, Cardiac↗
PubMedDate not supplied

Skylab task and work performance (experiment M-151--time and motion study).

The primary objective of Experiment M151 was to study by means of time and motion analytic techniques the inflight adaptation of Skylab crewmen to a variety of task situations involving different types of activity. A parallel objective was to examine astronaut inflight performance for any behavioral stress effects associated with the working and living conditions of the Skylab environment. Training data provided the basis for comparison of preflight and inflight performance. Efficiency was evaluated through the adaptation function, namely, the relation of performance time over task trials. The results indicate that the initial changeover from preflight to inflight (or, from 1-G to zero-G) was accompanied by a substantial increase in performance time for most work and task activities. Equally important was the finding that crewmen adjusted rapidly to the weightless environment and became proficient in developing techniques with which to optimize task performance. By the end of the second inflight trial, most of the activities were performed almost as efficiently as on the last preflight trial. In addition, the analysis demonstrated the sensitivity of the adaptation function to differences in task and hardware configuration. The function was found to be more regular and less variable inflight than preflight. Translation and control of masses (large or small) were accomplished easily and efficiently through the rapid development of the arms and legs (and the entire body) as subtle guidance and restraint systems. Finally, the adaptation function provided no evidence of behavioral stress effects attributable to the Skylab environment.

Adaptation, Physiological↗
PubMedDate not supplied

Skylab experiment M-171 "Metabolic Activity"--results of the first manned mission.

The experiment was performed to ascertain whether man's ability to perform mechanical work would be altered as a result of exposure to the weightless environment. Skylab II crewmen were exercised on a bicycle ergometer at loads approximating 25%, 50%, and 75% of their maximum oxygen uptake while their physiological responses were monitored. The results of these tests indicate that the crewmen had no significant decrement in their response to exercise during their exposure to zero gravity. Immediately postflight, however, all crewmen demonstrated an inability to perform the programmed exercise with the same metabolic effectiveness as they did both preflight and inflight. The most significant changes were elevated heart rates for the same work load and oxygen consumption (decreased oxygen pulse), decreased stroke volume, and decreased cardiac output at the same oxygen consumption level. It is apparent that the changes occurred inflight, but did not manifest themselves until the crewmen attempted to readapt to the 1-G environment.

Adaptation, Physiological↗
PubMed1976

Pulmonary function evaluation during the Skylab and Apollo-Soyuz missions.

Previous experience during Apollo postflight exercise testing indicated no major changes in pulmonary function. Pulmonary function has been studied in detail following exposure to hypoxic and hyperoxic normal gravity environments, but no previous study has reported on men exposed to an environment that was both normoxic at 258 torr total pressure and at null gravity as encountered in Skylab. Forced vital capacity (FVC) was measured during the preflight and postflight periods of the Skylab 2 mission. Inflight measurements of vital capacity (VC) were obtained during the last 2 weeks of the second manned mission (Skylab 3). More detailed pulmonary function screening was accomplished during the Skylab 4 mission. The primary measurements made during Skylab 4 testing included residual volume determination (RV), closing volume (CV), VC, FVC and its derivatives. In addition, VC was measured in flight at regular intervals during the Skylab 4 mission. Vital capacity was decreased slightly (-10%) in flight in all Skylab 4 crewmen. No major preflight-to-postflight changes were observed. The Apollo-Soyuz Test Project (ASTP) crewmen were studied using equipment and procedures similar to those employed during Skylab 4. Postflight evaluation of the ASTP crewmen was complicated by their inadvertent exposure to nitrogen tetroxide gas fumes upon reentry.

Aerospace Medicine↗
PubMed1976

Exercise cardiac output following Skylab missions: the second manned Skylab mission.

Cardiac output was measured during preflight and postflight exercise-stress tests on the Skylab astronauts. In the postflight tests immediately following the 28-, 59-, and 84-d earth orbital missions, the astronauts exhibited an approximate 30% decrease in cardiac output coupled with an approximate 50% decrease in cardiac stroke volume during exercise. These changes were accompanied by elevated heart rates and significant (p less than 0.01) increases in total systemic peripheral vascular resistance. Mean arterial pressure was unchanged. The hemodynamic alterations were transient in that all parameters returned to normal preflight values within 30 d of the end of the orbital period. Duration of the zero-G exposure did not appear to influence either the magnitude of the hemodynamic changes or the time-course of their return to normal. These results are discussed in relation to other cardiovascular findings and possible mechanisms responsible for the observations are outlined.

Adult↗
PubMed1976

Crew health status and monitoring summary: the second manned Skylab mission.

We have attempted to show that objective data used to assess crew health comes to the responsible physicians from the laboratories of the experimenters in sporadic and overwhelming amounts, but rarely in the real-time or near real-time frame which is preferred. The crew surgeon generates little hard data by his own efforts. Because of these factors, whenever an over-all clinical assessment of a particular crewman's fitness to continue a mission is an immediate necessity, it must too often be given on what the clinician would consider less than adequate data. Beginning on MD 28, weekly conferences were held with senior NASA management to make a "Go" or "No-Go" recommendation to continue or terminate the mission. In the absence of absolute indications of an unacceptable declining crew health, a clinical judgment was required. To tighten the criteria for decision-making, the authors selected factors that seemed indicative of overall health and plotted them both as real-time and percentage changes from preflight means. Other plots of the most readily available real-time and near real-time data were also developed for this purpose. The major success of this effort was the initiation of a method which indicated interesting and worthwhile possibilities if continued, refined, and computerized for more rapid availability. Correlation of actual post-flight findings with results anticipated from this method was gratifying but not statistically defensible. Whether or not this method would have forewarned of a serious decrement in crewmen's health cannot be known because, in fact, they were healthy and remain healthy.

Adult↗