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At least 19 recordsLinked to original sources

Multiple congenital malformations of the face, nervous system and musculoskeletal system of pigs.

Multiple congenital malformations occurred in 21 of 26 pigs (81%) in 3 litters from 2 piggeries. Two of 26 pigs (7%) were mummified while 3 of 26 (11%) were normal. Cheiloschisis was seen in all malformed pigs and was accompanied by various combinations of palatoschisis, arhinencephaly, hypoplasia of the spinal cord, arthrogryposis of the pelvic limbs, polydactyly, renal lesions and cauliflower ears. Histological examination suggested that arthrogryposis was due to neurogenic muscular atrophy. The teratogen was not identified.

Abnormalities, Multiple

An overview of neuroimmunomodulation and a possible correlation with musculoskeletal system function.

There is an increasing body of evidence that the nervous system is capable of modulating the immune response. Receptors for neuromodulators and neurohormones have been found on human T lymphocytes. Activation of these receptors can be stimulatory or inhibitory depending on the neuroactive substance. The immune system may be able to communicate with the nervous system using neuromodulators and neurohormones secreted by lymphocytes. Sympathetic innervation of lymphoid tissues is not restricted to blood vessels and smooth muscle, but directly supplies lymphocytes and blood precursor cells. It is theorized that spinal fixations may adversely affect the immune response through somatosympathetic reflexes. Spinal manipulation can correct the spinal fixations and may eliminate the adverse affects of somatosympathetic reflexes.

Humans

Laboratory diagnosis of postoperative sepsis of the musculoskeletal system.

The diagnosis of acute sepsis after musculoskeletal surgery is based on the results of the clinical examination. Microbiologic evaluation of clinical specimens permits identification of the causal organism(s) and of the susceptibility studies. In the subacute stage of postoperative sepsis, roentgenographic examination, a peripheral leukocyte count, erythrocyte sedimentation rate, hemoglobin level, and nuclear scans can be helpful to the clinician. Frozen section histologic examination of tissues and Gram staining of fluids obtained at surgery have resolved the choice in differential diagnosis between aseptic and septic loosening of painful prosthetic components. Laboratory evaluation, including tissue biopsy, identifies the chronic complications of amyloidosis and malignant change in patients with long term sepsis of the musculoskeletal system.

Arthritis, Infectious

[Tissue bank for the musculoskeletal system. Clinical applications].

From June 1987 to June 1990, the musculoskeletal system tissues bank of the Orthopaedics and Traumatology Department of the University Clinic of Navarra has used 310 allografts. Of this, 219 has been used in our Department, 142 of cancellous bone and 42 of cortical bone. 24 of patellar tendon and 11 of fascia lata. The other 91 grafts have been sent to other hospitals in the country. In the present work we make a retrospective study that included the patients who were operate with allograft. We observe the differences between several types of allografts comparing them with conventional surgery technics. Within the complications we distinguished a 10.52% of infection in cortical bone allografts used in patients with neoplastic treatment. In the other type of allograft we didn't present this complication. We concluded that a bone bank or a musculoskeletal system tissues bank has a great usefulness in different reconstructive surgery technics and arthrodesis. They are used more frequent in orthopaedics and traumatology surgery improving the development of this surgery.

Adolescent

Perspective: three-dimensional imaging of the musculoskeletal system.

An evaluation of musculoskeletal disorders in 202 patients using three-dimensional CT displays has revealed the usefulness of the technique, especially in patients with fractures of skeletal areas with complex anatomy, articular disorders of the hip, and spinal stenosis. In some cases, plastic models of diseased areas have been created from the CT data and are reasonably accurate, providing a graphic representation of the disease and the ability to perform rehearsal surgery. A preliminary investigation of three-dimensional displays of MR images indicates that the technique is feasible, although its clinical practicality requires further analysis.

Fractures, Bone

Evaluation of the musculoskeletal system with sonography.

Although musculoskeletal sonography historically has received little attention, its use in certain specific situations has clear advantages over use of other imaging techniques. The wide availability of sonography, its modest cost, and its lack of ionizing radiation are other reasons that its use in musculoskeletal conditions is expected to increase. We have reviewed potential applications; some of these applications are new and have been used in a small series of patients, and others, such as infant hip sonography, have already been used in thousands of cases. Additional applications may be possible [64]. Those learning the techniques of musculoskeletal sonography will find that progress is made most quickly when there is close cooperation between the sonographer and the clinician. While experience is being gained, each party must endeavor to understand what the technique is able to determine and what it cannot determine. Only through close cooperation, and with adequate opportunity to learn, will the sonographer and the clinician develop confidence in the technique to the point that it becomes the effective imaging alternative that best suits the needs of the patient.

Achilles Tendon

Alcohol consumption and complaints from the musculoskeletal system among engine drivers--an epidemiological study.

The purpose of this study was to test the hypothesis that a positive correlation exist between level of alcohol consumption and complaints from the musculoskeletal system. 150 randomly selected engine drivers from Sweden were interviewed about complaints from the musculoskeletal system during the last 12 months. In this study the complaints from the neck, shoulders and lower back were investigated. An index counting number of regions with complaints was computed. The subjects were asked to report their level of alcohol consumption during the last month (beer, wine and spirits). The total alcohol consumption was calculated expressed in terms of 40% pure alcohol. The median consumption was 39.5 cl/month. The engine drivers reporting complaints from the neck had a significantly higher consumption of alcohol than those without such complaints. A positive significant correlation existed between the number of complaints (index) and alcohol consumption.

Adult

Screening for congenital dislocation of the hip, scoliosis, and other abnormalities affecting the musculoskeletal system.

The three main conditions affecting the musculoskeletal system currently being screened for are spina bifida cystica, congenital dislocation of the hip, and scoliosis. The techniques of screening are different for each: amniotic fluid analysis for spina bifida cystica, a manual physical examination for congenital dislocation of the hip, and a visual examination for scoliosis. Properly time amniotic fluid analysis for alpha-fetoprotein is both a sensitive and specific test for neural tube defects. However, because of the low incidence of spina bifida cystica, this examination is justified only in high-risk pregnancies. Maternal serum screening has not achieved widespread acceptance because of its lack of sensitivity and the low and apparently falling incidence of the deformity. The neonatal manual examination for congenital dislocation of the hip is now well established and widely practiced. Almost all agree that the incidence of persistent congenital dislocation of the hip has been lowered as a result. However, the examination lacks both sensitivity and specificity because of intrinsic difficulties with the examination and the occurrence of late onset subluxation and dislocation. It is becoming apparent that congenital dislocation of the hip is a dynamic problem in the peri- and early neonatal period. Repeated careful evaluation of the hips during infancy is necessary to make the diagnosis as early as possible. To further enhance early detection, it may be necessary to consider obtaining an anteroposterior pelvis radiograph at age 4 to 6 months in babies at high risk. The visual evaluation for scoliosis is a very sensitive test but lacks specificity. Efforts are now being made to quantify visual screening techniques and thus decrease the numbers of false-positive examinations.

Adolescent

Drug-induced lesions of the musculoskeletal system.

Drugs, whether prescribed by physicians or taken without the knowledge of the physician, may result in profound changes in the musculoskeletal system. Some drugs may produce teratogenic changes in the developing fetus frequently, but not necessarily, in association with anomalies of other systems. Other drugs may have their effects on the child or adult, whereas a number of drugs result in either teratogenic or nonteratogenic abnormalities. In the course of evaluating any diagnostic imaging study, it is essential that the radiologist be aware of any drugs that the patient may be taking and be knowledgeable of the radiologic changes that such drugs may produce in the musculoskeletal system.

Abnormalities, Drug-Induced

Mycobacterial disease in the musculoskeletal system.

Over a six-year period, 12 patients were admitted to a Melbourne teaching hospital with mycobacterial infections of the musculoskeletal system. Four of the infections involved soft tissue and these included three atypical mycobacterial infections. The average age at diagnosis was 60 years. Five patients were born outside Australia. The predisposing factors included a past or family history of tuberculosis, pre-existing arthritis, alcoholism, earlier trauma, and membership of certain occupations. The average delay in diagnosis was four months. Treatment involved a combination of appropriate medication and surgical procedures that ranged from diagnostic aspiration to amputation. Mycobacterial infection of the musculoskeletal system, although uncommon in Australia, remains an important problem that requires continued awareness for early diagnosis.

Adult

[Treatment of chronic pain of the musculoskeletal system by epidural stimulation].

In order to reduce refractory chronic pain of the musculoskeletal system, the orthopedic surgeon can stimulate electrically the peripheral nerves or the posterior funiculi of the spinal cord (epidural neurostimulation). The authors specify their current indications for epidural stimulation in the treatment of such painful diseases: radicular pain caused by arachnoepidurites, sequelae of trauma inflicted to the spine and medulla; postoperative lomboradicular pain of mixed source, and distal lesions of the plexus brachialis. The indication for an implant stems from a rigorous strategy which requires more particularly that pain regress by more than 50% under transcutaneous neurostimulation applied for a period of least one month and that the psychological and spinal-cerebral integrity be verified. The surgical procedure comprises two stages: first, positioning of an epidural electrode and, then, insertion of a totally implantable multiprogrammable radiostimulator. Judging from a prospective assessment of 20 cases of postoperative lumbar arachnoepiduritis treated in this way, the results are considered quite encouraging.

Analgesia, Epidural

Sonography of the musculoskeletal system.

High-resolution ultrasound is an imaging technique with increasing applications in the musculoskeletal system. With the development of high-frequency, realtime transducers, detailed images of small superficial structures can be provided. Tendons, muscles, and subcutaneous tissues can be assessed for disruption, masses, or fluid collections. Foreign bodies can be localized to guide surgical excision. Increased use of this diagnostic tool may lead to new applications as the technology improves.

Bone and Bones

Sonography of the musculoskeletal system.

Improved technology and the development of high-resolution transducers have made sonography of the structures of the musculoskeletal system possible. The vast majority of scientific reports on the value of sonography for imaging musculoskeletal abnormalities have been written only in the last decade. Sonography has several inherent advantages: it is relatively inexpensive, allows comparison with the opposite normal side, uses no radiation, and can be performed at bedside or in the operating room if necessary. The advent of MR imaging has revolutionized musculoskeletal imaging and may be used in many instances rather than sonography for evaluating the same abnormalities or anatomic structures. It is important, however, to keep in perspective what the different imaging techniques have to offer, and, if one is just as efficacious as the other, the least invasive and least expensive should be chosen whenever possible. The goal of this article is to review the applications of sonography to the evaluation of musculoskeletal disorders including tendon disease, soft-tissue masses, identification of foreign bodies, osteomyelitis, cellulitis, and certain joint abnormalities.

Aneurysm

Magnetic resonance imaging of the musculoskeletal system. An overview.

Several of the features of magnetic resonance imaging (MRI) are advantageous for diagnostic examination of the musculoskeletal system. For example, the excellent depiction of bone marrow makes it a very sensitive method for identifying trauma, tumor, ischemia and infection of the marrow space. In addition, the high-contrast discrimination of soft tissues and the ability to make thin-section images in any plane allows for the depiction of abnormalities involving the muscles, ligaments, tendons, and neurovascular structures. The major disadvantages are the nonspecificity of many of the findings, the high cost of examinations, and the limited number of available MRI units. MRI is most appropriately utilized when it can be expected to provide diagnostic information not available from less-expensive noninvasive diagnostic methods and when the results of the examination may significantly affect patient management. To get the most out of the examination, it should be performed and interpreted with knowledge of clinical findings and results of other imaging tests, especially plain roentgenograms. To date, MRI has proved to be most useful for the evaluation of the spine, shoulder, hip, and knee.

Bone Diseases

An analysis of the sources of musculoskeletal system impedance.

When antagonistic muscles co-contract, the impedance of musculoskeletal systems to applied loads is known to increase. In this paper a physiologically-based, higher-order, nonlinear antagonistic muscle-joint model is utilized to clarify the sources of impedance modulation during a variety of tasks, ranging from resisting transient loads to holding steady loads to making fast movements in unpredictable surroundings. It is shown that impedance modulation occurs automatically as a function of the specific operating ranges utilized during a given task by each of four different muscle-joint mechanical relations. The relative contribution of each relation depends on the type of task, with impedance during quasi-static conditions sensitive to muscle tension-length and sometimes joint parallel elastic properties and during dynamic tasks dominated by the series element and muscle force-velocity properties. Elimination of any of these causes a decrease in built-in biomechanical capabilities. These findings raise questions concerning past theories on stiffness-impedance modulation which appear to underestimate the role of inherent biomechanical properties.

Biomechanical Phenomena

[Echography of the musculoskeletal system].

The recent, highly efficient and simple systems have enabled ultrasound to find a specific place in the imaging of the musculoskeletal system within a few years. The daily "on-site" examination currently completes plain radiographs with a particularly effective, non-traumatic and cheap exploration of a number of pathological cases, including traumatic musculotendinous lesions and periarticular soft tissue. After describing the normal images and the semiology of the major diseases for which this technique can be used, the author reviews the appearance of the main regional osteoarticular lesions (shoulder, hip, knee, extremities, etc.), with ultrasound.

Bone Diseases