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Results for “Muscle Tonus”

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At least 19 recordsLinked to original sources
PubMedDate not supplied

[Dantrium in the treatment of increased muscle tonus in patients with multiple sclerosis].

In 19 patients with multiple sclerosis and 1 with subacute sclerosing panencephalitis the mean increase in muscle tonus was found to be 3.1 (range 1--4 according to Burke-Ashwort). In 10 controls with multiple sclerosis the mean spasticity was 2.4. Dantrium was given in doses up to 800 mg for 14--16 days and it caused a greater reduction of spasticity than placebo (p less than 0.05). In 12 patients (60%) varying degrees of muscle tonus reduction was observed. In 11 patients the efect of Dantrium was compared with that of other drugs (Clonazepam, Tetradiazepam, Carisoprodol and Lyoresal). In 6 cases Dantrium was a more effective drug than other muscle relaxants and in 5 cases no difference was observed or other drugs were superior to Dantrium.

Adult↗
PubMedDate not supplied

[Muscle tonus in rigidity and spasticity].

The results of the examination of the muscle tone by passive movement of the extremity at a low and high rate in patients with spasticity are discussed. In parkinsonism high resistance was noted to passive movements of the extremity at a low rate (with a period of oscillatory movement of 100 s and more) as well as in the first cycles of rapid sinusoidal movement (with a period of 1 s) if the extremity had been at rest for a lengthy period of time. In spasticity of other etiology, there was a gradual increase of the amplitude on the mechanomyogram in high rates of passive movements, which was evidently due to growth of stimulation in the stretch-reflex arc from cycle to cycle as the result of sumation with trace stimulation from the preceding cycles. The shape of the spectromechanomyogram, which is marked by a rise in the region of the high rates, is considered to be a sign of spasticity, whereas the size of this rise is accepted as a quantitative index of the spastic component of the muscle tone.

Electromyography↗
PubMedDate not supplied

[Device for studying muscle tonus].

A portable device for studying the muscular tone can be constructed on the principle of registering displacements of a metal rod accomplished by means of the bridge network. The indicating instrument is calibrated with reference to the steel rod, whose density (tightness) is taken as an ultimate one, while the tightness of the muscle tissue is determined in per cent of the ultimate tightness.

Muscle Tonus↗
PubMedDate not supplied

[Effect of dentatotomy on muscle tonus in infantile cerebral palsy].

The article deals with the results of the quantitative study of the muscular tonus in patients with infantile cerebral paralysis by the method of passive sinusoid movements of the arm at the elbow joint at various rates, with a period of T = Is to T = 200s and its assessment by the value of the mechanical resistance of the extremity in the region of high (T = I--4s) and low rates (T = 50s). The spectromechanomyographic method of examination revealed two components in the muscular tonus: an increase in the region of high rates, which were identify as the spastic component of the muscular tonus, and an increase in the region of low rates, which is identified with the rigid component of the muscular tonus. Operative destruction of the cerebellar dentate nuclei in patients with infantile cerebral paralysis naturally reduces this spastic component, but hardly changes the rigid component. One of the factors causing changes in the shape and amplitude of choreothetoid hyperkinesia in patients with infantile cerebral paralysis may evidently be the redistribution of the tonus in different muscular groups and changes in the correlations between its spastic and rigid components.

Adolescent↗
PubMed1975

The effect of berotec (Th 1165a) on spontaneous and induced uterine activity in the pregnant baboon.

Berotec (Th 1165a), a specific beta-adrenergic agent, has been found to be a more potent agent than metaproterenol in the inhibition of uterine activity in animals and human beings. The effect of berotec on spontaneous (postinduced) and induced uterine activity in the pregnant baboon near term was investigated. Berotec administered intravenously in a dose of 5 mug per minute consistently and significantly reduced spontaneous uterine activity as well as uterine activity by either oxytocin or prostaglandin F2-alpha. The frequency of contractions was consistently reduced whereas the effect on the amplitude of contractions was less marked. There was no reduction of the baseline muscle tonus. Berotec infusion produced a marked increase in the maternal heart rate, averaging 40 beats per minute. Berotec appears to be a potent inhibitor of spontaneous, oxytocin-induced, and prostaglandin-induced uterine activity in the pregnant baboon, but it has considerable cardiovascular side effects.

Adrenergic beta-Agonists↗
PubMed1976

Cyclic EEG and motility patterns during sleep in restrained infant rats.

When restrained in a quasi-fetal position, infant rats (2--3 weeks old) remain for an extended period in a sleep-like state as judged by polygraphic criteria. Moreover, they become very difficult to arouse by sensory stimuli, and show a level of spontaneous motility considerably higher than is normally found at this age during sleep. Phasic generalized body movements, which are often quite stereotyped, occur in trains at regular intervals, against a low background level of neck muscle tonus. The amplitude of the cortical EEG, especially in the delta band, is negatively correlated with the frequency of spontaneous motor burst activity. It is suggested that these REM-like "rapid body movements" in immature mammals may well represent a transitional stage between fetal behavior patterns and sleep motility in the adult organism.

Age Factors↗
PubMed1977

[The influence of vasodilatators on intraocular pressure and blood pressure (author's transl)].

The influence of different vasodilatators on blood pressure and intraocular pressure has been tested in animal experiments. For that purpose substances with alphasympathicolytic effect (Hydergin, Trental) have been tested as well as substances which are of direct influence on the muscles. In all cases a decrease of the blood pressure was noticed. Furthermore in most of the cases an increase of the intraocular pressure could be seen. This is due to a direct dilatation of ocular vessels. The effects were short-lived and reversible. We tried to find an explanation for the variations of intraocular pressure during the decrease of blood pressure. The low transmural pressure (PTM) and the corresponding low starting point of the muscle tonus seemed to be responsible for this phenomenon. Without doubt the starting point of the blood pressure, the dose, and the cardiac ability for compensation are of great influence in the development of the curve. Only a sufficiently high blood pressure is able to dilate the ocular vessels, so that one has to draw therapeutic conclusions from the constellation blood pressure/intraocular pressure before deciding on treatment.

Animals↗
PubMed1979

[A method for differentiation between the participation of the smooth and the cross-striated anal sphincter muscles in resting tonus].

By means of simultaneous recordings of the external anal sphincter EMG activity and the anal resting pressure with at least ten voluntary sphincter contractions, it is possible to estimate by correlation calculation the resting pressure exerted by the internal anal sphincter. The value of the method had been proved by comparing investigations in conscious and curarized patients under general anesthesia. In patients with hemorrhoids and chronic constipation, the amount of internal pressure found in the resting tonus (91% in hemorrhoids, 55% in chronic constipation) was significantly different when compared with a health group. The comparison of only the resting pressure did not show a significant difference.

Anal Canal↗
PubMed1978

The syndrome of 'continuous muscle fiber activity.'.

A 7-year-old boy who suffered from increasing stiffness and contractures of the extremities had distally pronounced atrophy and absent tendon reflexes. Electromyography showed continuous electrical activity during rest, sleep, after intravenous injection of diazepam, and after peripheral nerve block. The H reflex was elicitable; the silent period after the reflex was absent. Histopathological examination of the peroneus muscle disclosed a marked preponderance of type I fibers and slight atrophy of the type II fibers. Electron microscopic examination of the endplates demonstrated a marked atrophy of the postsynaptic regions and widened synaptic clefts. After one year's treatment with phenytoin, 200 mg daily, the patient showed an almost normal muscle tone. As not all of these electrophysiological phenomena can be fully explained by disturbances of the nerve terminals or the endplates, a further anomaly proximal from the peripheral nerve block seems to have been present.

Child↗