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At least 19 recordsLinked to original sources

Experimental salivary mucoceles in cat. A histochemical study.

Ductal ligation of the sublingual gland induced mucocele formation in a high percentage of cats. Extravasated mucus was associated with all sublingual glands up to 20 days after ligation, and extravasation mucoceles were associated with 12 out of 27 sublingual glands between 7 and 365 days after ligation. Enzyme-histochemic examination revealed that the extravasated mucus induced a migration of macrophages and a fibroblastic reaction. It is thought that if these reactions are sufficiently intense in the early days after ligation, then continued spread of extravasated mucus and mucocele formation does not occur; however, if the extravasation is too great to be contained, a mucocele forms in which a balance develops between extravasation of mucus and its removal. Possibly the numerous macrophages in the mucoceles are involved in degrading mucus and facilitating its removal.

Acid Phosphatase

Mucoceles of the appendix. Their relationship to hyperplastic polyps, mucinous cystadenomas, and cystadenocarcinomas.

Sixty-four cases of hyperplastic polyp, mucinous cystadenoma, and cystadenocarcinoma of the appendix were studied in relation to the development of mucocele and "pseudomyxoma peritonei." Thirty-three cases were examples of hyperplastic polyps. In 11, the appendix was transformed into a mucocele; eight were associated with mucinous cystadenoma and one with mucinous cystadenocarcinoma. The hyperplastic polyp alone was the cause of mucocele formation in two. Thirty-five cases represented examples of mucinous cystadenoma; 32 resulted in mucocele formation. Rupture with localized pseudomyxoma peritonei was found in six; generalized pseudomyxoma peritonei was encountered only once. In four of the five cases of mucinous cystadenocarcinoma, the appendix was grossly transformed into mucoceles. The histological features of mucinous cystadenoma are identical to villous adenoma of the large bowel and probably represent its counterpart within the appendix.

Aged

Bone thinning in frontal mucocele.

Sixteen cases of frontal mucocele are reviewed. Bone thinning leading to destruction of the sinus floor was shown to be a feature. It usually affects the superomedial margin of the orbital roof first, due to pressure on the area where the sinus wall is thinnest. Demonstrable thinning of either anterior or posterior sinus walls--a cardinal sign of frontal mucocele, is best shown by means of underpenetrated lateral radiographs. All other conventional radiographic signs of frontal mucocele, including lucency of the affected sinus, were found to be non-specific. The presence of an osteoma in a site likely to obstruct the frontonasal duct is a valuable adjunct to diagnosis.

Adult

Postoperative mucoceles of the maxillary sinus.

Apparently, the incidence of postoperative maxillary sinus mucoceles is greater in Japan than in the Western world. Between 1967 and 1976 at the Tokyo Medical and Dental University Hospital, Department of Otorhinolaryngology, 132 patients had the diagnosis of mucoceles of the maxillary sinus. Of these patients, 131 (99%) had histories of previous maxillary sinus surgery. A number of etiologic mechanisms are probably involved in producing these mucoceles.

Adolescent

Zygomatic salivary mucoceles in the dog.

Zygomatic salivary mucoceles were diagnosed in 2 dogs. Ophthalmologic signs differed in both cases and reflected the position of the mucocele in relation to the orbit. Cytology of aspirated material and sialography were performed in both cases, but his enabled confirmation of the diagnosis in only one. Surgical excision of the zygomatic salivary gland, with drainage of the mucocele, was curative in both cases. Both dogs had a history of trauma to the head.

Animals

Saccular mucocele and laryngeal cancer.

Saccular mucoceles are a definite entity and probably occur more frequently than is supposed. Confusion with internal laryngoceles is possibly due to lack of understanding of basic anatomy and physiology. A 49-year-old man had a saccular mucocele that was possibly associated with laryngeal cancer, although a definitive diagnosis was only made two years later. The laryngectomy specimen was serially sectioned and showed an internal laryngocele on the side that was not operated one. This patient remains alive and well four years after excision of a T4 carcinoma, although a unilateral radical neck dissection was performed two years ago.

Animals

Ethmoidal mucoceles.

Twenty ethmoidal mucoceles were treated and observed for a minimum of two years after surgery. Unilateral exophthalmos was the initial complaint in all cases and nasal polyposis was a noteworthy finding in more than half of the patients. The lesions always extended into the orbit and usually eroded the floor of the frontal sinus. Exenteration through an ethmoidectomy approach was successful in 16 cases. Failure was due to recurrence of the mucocele in one case and in three cases to uncontrolled polypoid disease that produced recurrence of the exophthalmos. Long-term follow-up is mandatory since recurrences may take several years to occur.

Adolescent

Chiasmal syndrome in sphenoid sinus mucocele.

Two patients with sphenoethmoid mucoceles developed visual field defects consistent with optic chiasm dysfunction. The presence of chiasmal field defects associated with the clinical syndrome of compressive optic neuropathy should not rule out the diagnosis of sphenoethmoid mucocele since definitive treatment can be carried out via transnasal drainage.

Adolescent

Paranasal sinus carcinoma causing orbital mucocele.

Three patients presented with typical orbital mucoceles. However, subsequent histopathologic study revealed paranasal sinus concomitant squamous cell carcinoma in all three cases. Careful histologic investigation is necessary before considering orbital mucocele a benign process.

Aged

Salivary mucoceles.

A survey of natural mucoceles revealed that there were two types, namely, extravasation and retention, and that extravasation mucocceles occurred most often in younger patients and in the lower lip, whereas retention mucoceles occurred most often in older patients and elsewhere in the mouth.

Acid Phosphatase

Mucocele of the appendix secondary to obstruction by endometriosis.

A mucocele of the appendix secondary to obstruction by endometriosis is reported and the relevant literature reviewed. The theories of the pathogenesis of appendiceal mucocele are reviewed and discussed. To our knowledge, no similar, well documented case has been reported.

Adult

Mucocele of the paranasal sinuses. A retrospective clinical and histological study.

Clinical and radiological findings in 112 patients with muco/pyocele in the paranasal sinuses are presented. The modified Lynch-Howarth operation gave a primary cure rate of 82% which is satisfactory compared with other reports. Histological examination of the mucocele membranes and anamnestic information support the theory that a mucocele develops secondary to obstruction of the sinus outlet.

Adolescent

Mucocele of the petrous apex.

The first case of a primary mucocele of the petrous apex is presented and the differential diagnosis is briefly discussed. Since this area is unavailable for direct examination, a thorough radiographic evaluation is essential. A mucocele should be suspected when a lytic lesion has a multiloculated appearance and when the contralateral petrous apex is highly pneumatized. Even then, a biopsy may still be needed to make a definitive diagnosis. The appropriate treatment for these cystic lesions is fistulization into a radical mastoid cavity or an exteriorized sphenoid sinus.

Adolescent

Sudden blindness in a child: presenting symptom of a sphenoid sinus mucocele.

A 10-year-old girl with no nasal or respiratory symptoms developed a headache lasting a few hours. The next day she became totally blind in the right eye and over 5 days vision in the left eye deteriorated to bare light perception. The diagnosis of a sphenoid sinus mucocele was made radiologically and drainage via an endonasal sphenoidectomy produced 12 ml of brownish fluid. Endoscopic biopsy of the wall confirmed the diagnosis of a mucocele. Steroid treatment was given postoperatively, but vision recovered to 6/12 in the left eye only. The importance of urgent clinical diagnosis and treatment is stressed.

Acute Disease

Evaluation of mucoceles of the paranasal sinuses with computed tomography.

Eighteen patients with mucoceles of the paranasal sinuses were studied by plain radiography, pluridirectional tomography, and computed tomography (CT). Sixteen of the lesions had a homogeneous appearance on CT but demonstrated variable absorption characteristics, with acutely infected mucoceles showing rim enhancement. Plain radiography and pluridirectional tomography were usually sufficient for making a diagnosis and defining the extent of the lesion, but CT more accurately demonstrated orbital and intracranial extension. Both transverse and coronal CT are essential for adequate evaluation.

Adolescent

Paranasal sinus mucoceles in children.

The clinical and radiographic features of paranasal sinus mucoceles in 6 pediatric patients are discussed. These lesions may be associated with clinical signs of a periorbital or intracranial mass. Characteristic radiographic findings can suggest the preoperative diagnosis, although a sphenoid sinus mucocele may simulate more serious conditions.

Adolescent