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At least 19 recordsLinked to original sources

[The ontogenesis of the manubrium sterni in Tupaia belangeri].

The morphogenesis of the manubrium sterni was studied in a series of dated embryos of Tupaia belangeri. In addition to the sternal bands, the "paired suprasternal Anlage" takes part in the shaping of the manubrium sterni as reported by Klima (1968) for other mammals. It forms skeletal elements that mediate between the clavicle and the manubrium: the sternocalvicular ligament and the paired prominence on the dorsal surface of the manubrium, which underlies the clavicles. The paired prominence corresponds to the praeclavium present in some therians. Very probably, the discus articularis of the sternoclavicular articulation of some primates can be attributed to the suprasternal Anlage. There was, however, no indication that the ossa suprasternalia of primates develop from the suprasternal Anlagen: In Tupaia these Anlagen do not form the cranial part of the manubrium. Klima's "unpaired Anlage" develops differently in Tupaia than in other therians. It consists of connective tissue and is not integrated into the manubrium. It presents an insertion surface for the M. pectoralis major, which shifts its origin onto the manubrium, after the sternal bands have fused. The homology of the "unpaired Anlage" and the "pars chondralis interclaviculae" is doubtful.

Animals

On the degree of rigidity of the manubrium in a finite-element model of the cat eardrum.

It has always been assumed that the manubrium is in effect perfectly rigid. In this paper, a more realistic model of the manubrium is incorporated into an existing finite-element model of the cat eardrum. The manubrial thickness is based on a three-dimensional reconstruction from serial histological sections. After a review of the literature, a value of 2 x 10(11) dyn cm-2 is adopted for the Young's modulus of the bone. The mode of vibration of the model is investigated for different manubrial-thickness values and it is found that a significant degree of manubrial bending occurs in the model for realistic values of manubrial thickness. As a result of the bending, the frequency response at the umbo at high frequencies displays much higher amplitudes and larger phase lags than when the manubrium is rigid. The bending will also affect the displacements transmitted to the ossicular load, and introduce significant errors into estimates of such displacements based on measurements of umbo displacement even at frequencies as low as a few kHz. Recent measurements of manubrium vibrations in the cat ear provide experimental evidence of bending.

Animals

Resection of the manubrium.

Direct exposure of the superior mediastinum is essential when resecting subglottic tumours of the larynx, neoplasms of the cervical trachea or cervical oesophagus. This facilitates low resection of the trachea and clearance of the paratracheal nodes. This may best be carried out by removal of most of the manubrium sterni and both sternoclavicular joints and this operation has been performed in 22 patients with minimal morbidity or long term disability.

Esophageal Neoplasms

Radiology of postnatal skeletal development. II. The manubrium and sternum.

Thirty-six manubriosternal composites from skeletally immature cadavers were examined morphologically and radiographically. Sternebral ossification followed certain patterns. The manubrium (first sternebra) usually had one primary ossification center and one or two smaller centers. These usually were caudad to the major center (longitudinally bifid). The second sternebra invariably had only one ossification center. The third and fourth sternebrae had latitudinal (right-left) bifid ossification centers, undoubtedly a result of the original formation of the sternum from two longitudinal mesenchymal anlagen. Occasionally the fourth sternebra exhibited longitudinally bifid ossification. The usual pattern was ossification of four sternebrae, although a fifth was intermittently present. The xiphisternum (not a true sternebra) was infrequently ossified.

Adolescent

Chondrosarcoma of the manubrium. Resection and reconstruction with pectoralis major muscle.

Chondrosarcomas of the sternum are best treated by resection with tumor-free margins. Reconstruction of the manubrium and superior aspect of the sternum is one of the most difficult challenges for the reconstructive surgeon. In the past, most of the structural stability following resection of this area has depended on the formation of dense fibrous tissue and scar. We presented a case of reconstruction of the bony defect with autogenous bone grafting in conjunction with transposition of the pectoralis major muscle for increased protection and stability of the chest wall as well as for nourishment for the bone graft.

Chondrosarcoma

Heterodyne interferometer measurements of the frequency response of the manubrium tip in cat.

A heterodyne interferometer proved to be a very accurate tool to measure amplitude and phase of the malleus response during acoustical stimulation. It was shown that to obtain equal accuracy in the acoustical pressure measurements, pressure response must be remeasured at short time intervals. At frequencies above 4 kHz various gross resonances are apparent on the frequency response curves. The resonances are, depending on the animal, more or less pronounced. As a result of the improved accuracy changes of the malleus vibration response with time could clearly be discriminated. These changes can be related to shifts in frequency of the position of these resonances. Comparison of experimental frequency response and lumped parameter model predictions from literature shows that these resonances are not present in the model responses.

Acoustics

[Anatomical considerations in sternal puncture].

The thickness of the manubrium, the width and thickness of the body of the sternum at the level of second intercostal space as well as the thickness of the spongiosa and outer and inner compact layers have been measured in 67 human cadavers. Consequently, it is recommended that sternal puncture be made at the level of the second intercostal space in the adult and at the manubrium in children. Depth of puncture should not exceed 4 mm. Sternal puncture can thereby be done with greater confidence of avoiding penetration of the sternum, a potentially serious complication.

Adult

Mediastinal dissection--1976: indications and newer techniques.

Head and neck neoplasms may invade the mediastinum by direct extension or metastases to the tracheoesophageal or jugulo-subclavian lymph nodes. The clavicles and manubrium are a barrier to adequate resection in this type of disease. In 1962, the senior author reported six mediastinal dissections for stomal recurrences after laryngectomy. Later techniques for staging the removal of manubrium and clavicles and preparing the regional flaps were devised to avoid major complications arising from operating in this area which usually had prior treatment with radiation and/or surgery. Over 60 transsternal radical neck dissections have been performed in the past 20 years. We have in the past evaluated the morbidity and survivals in stomal cases and present here our revised indications and techniques.

Dissection

[Skeletal changes in Down's syndrome. A correlation between radiological and cytogenetic findings (author's transl)].

One hundred and two patients with Down's syndrome aged one day to 17 years were examined radiologically, seven of these repeatedly. Films obtained included the chest in two planes, lateral spine, left hand and pelvis. The following features were noted; the number of paired ribs, ossification centres in the manubrium, height of lumbar vertebral bodies, shortening of the phalanges, bone age and calculation of the acetabula and ilial angle and ilial index. In all patients the chromosomes were examined in order to determine the cytogenetic type. The following features were found to be more common in Down's syndrome than in normals: abnormal ossification of the manubrium (33%), aplasia of the twelfth rib (18%), high lumbar vertebral bodies (50%), brachymesophalangia of the fifth ray (62%) and changes in skeletal maturation (acceleration or retardation in 48%). Changes in the pelvis were typical; with increasing age, the acetabular angle falls and the ilial angle increases. The most striking skeletal changes were found in 84 patients with trisomy 21.

Adolescent

[Ormiersia carcini gen. n., sp. n., microsporidian of the Mediterranean crab, Carcinus mediterraneus Czerniavsky, 1844: developmental cycle and ultrastructural study].

A microsporidan parasite, Ormieresia carcini gen. n., sp. n., was found in the crab, Carcinus mediterraneus Czerniavsky. Its development and fine structure are the subject are the subject of the present study. The life cycle begins with a schizont surrounded by a unit membrane and containing a diplokaryon. The entire process of sporogony takes place in the host musculature. The sporogonic stages are enclosed in the pansporoblastic membrane. In each pansporoblast, sporogony gives rise to 8 sporoblasts; the octonucleate sporogonial plasmodium is lacking. In the course of schizogonic and sporogonic divisions, each kinetic center consists of 2 plaques, one located within and the other outside the nuclear envelope. The dividing sporonts and sporoblasts sevrets "metabolic" substances (granules, tubules) which are depostied in the pansporoblast. The uninucleate spore is long and cylindrical, measuring 19.1 X 2.4 micronm. A rectilinear manubrium traverses the spore. Its posterior end attenuates abruptly into a polar filament with 4 or 5 coils; its anterior end is attached to the polar cap, which is compressed by a double polar ring. The anterior part of the manubrium is surrounded by a polaroplast consisting of a "spongy" (vesicular) and a lamellar zone.

Animals

Papers and articles measurement of central venous pressure in horses.

Central venous pressure measurements were made in 74 horses and ponies free from clinical evidence of cardiopulmonary disease. Using the sternal manubrium as the zero reference point, the mean value obtained was 12 cm H2O (S.D. +/- 6). There was a significant correlation with body weight (r=0.6, p less than 0.001) but there was none with age, sex, breed or type. During halothane anaesthesia, using the same reference point, the mean value was 24.5 cm H2O (S.D. +/- 6) in 28 animals in right lateral recumbency, 29 cm H2O (S.D. +/- 8) in 17 animals in left lateral recumbency and -6 cm H20 (S.D. +/- 4) IN 27 supine animals. The use of the sternal manubrium as zero reference point did not allow comparison of values in standing and recumbent animals and it was considered that serial measurements were of more value than isolated determinations in assessing the circulatory state of an animal.

Acepromazine

Vascular pattern of the guinea pig tympanic membrane.

The vascular organization of the guinea pig tympanic membrane was studied by light microscopy in India-ink-, colored-gelatin-, or horseradish peroxidase (HRP)-injected specimens. The ultrastructural localization of the vessels was examined by transmission electron microscopy in HRP-injected material. We found that the tympanic membrane is supplied by two arterial sources, the superior and inferior tympanic arteries, both of which arise from the posterior auricular artery. The superior tympanic artery gives off arterioles which, in the tympanic membrane, run centrifugally from the attachment of the manubrium, while the inferior tympanic artery emits arterioles which run centripetally from the tympanic annulus. Both sets of arterioles divide into capillaries and form a monolayered polygonal meshwork. The capillaries drain into venules which run between arterioles in the membrane and empty into either the superior tympanic vein located at the manubrium or the inferior tympanic vein at the annulus.

Animals

An electrode montage for electrocardiographic monitoring.

An electrocardiographic electrode montage is described using electrodes mounted on the manubrium sterni (RA), xiphisternum (LA) and V5 position (LL). The lead II setting on the monitor, equivalent to CM5, offers optimal ischaemia detection, while lead I, now a vertical lead, manubrium to xiphisternum, results in maximal P wave amplitude. The montage has been evaluated in sixty-two intensive care patients with electrocardiographic abnormalities and has been used extensively in intensive care, the operating theatres and in shock wave lithotripsy. The 'Prince Henry' montage offers advantages over the standard bipolar leads in P wave amplitude, arrhythmia diagnosis and artefact rejection.

Arrhythmias, Cardiac