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Villous processes from the inner segments of cones in the human macula lutea.

The cones of the human macula lutea were examined by scanning electron microscopy. It was found that each inner segment had about 15 thread-like processes which projected from the cell surface. They were arranged in a longitudinal straight line along the photoreceptor, and were directed away from or towards the fovea contralis. The villous processes may be analogous with the lateral fins of the inner segments of certain vertebrates. They may perhaps bridge the space between neighbouring photoreceptors and may establish contact and interaction between them.

Adult

[Microsurgery of the macula lutea].

Modern surgery of the macula exists since 1965, and was initially proposed in membrane removal from patients presenting an idiopathic epiretinal membrane. This first indication authorized the development of macular microsurgical instrumentation and further analysis of membrane fragments. However, the exact pathogenesis of these membranes remains yet unknown. Since 1991 macular surgery was applied in the treatment of macular holes. Results obtained after macular hole surgery confirmed pathogenic hypothesis observed clinically by Gas. Considerable improvement was therefore achieved in anatomical and functional outcome. Chorioretinal adhesion agents were recently proposed to optimize the closure of macular holes. Submacular surgery is the latest technologic achievement under investigation. The ultimate indications are age-related macular degeneration, first cause of blindness in industrialized countries. Retinal transplantation opens new avenues in the treatment of a large number of chorioretinal diseases. The assessment of macular surgery could pave the way in realising such technical advances.

Humans