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[The pathologic theory of the oriental medicine].

The oriental medicine differs from the western medicine in many aspects. Especially they show great differences in their understanding of diseases as the object of medical science. But their differences were often exaggerated and accentuated. In this article I would like to reveal various aspects of oriental medicine which have often been ignored by schematic comparison with the western medicine. They are as follows. 1) The pathologic theory of the oriental medicine has changed as the time has gone by. 2) The pathologic theory of the oriental medicine is not based on single paradigm. 3) Nosologic problems in oriental and western medicine.

Asia↗

Concepts of traditional Oriental medicine.

BACKGROUND: Traditional Oriental medicine is taught and practiced in many parts of the world, including the United States. It is based on centuries-old philosophies of disease causality and on empirical validation of diagnostic and treatment procedures. This article presents a perspective on traditional Oriental medicine. METHODS: The traditional Oriental medicine physician considers the body to normally be in a state of balance or harmony that can be disrupted by certain pernicious influences. These influences affect various body systems in ways that can be detected using a four-part examination, which includes looking, listening and smelling, asking, and touching. During the examination, special emphasis is placed on analyzing the rate and rhythm of the pulse. RESULTS: Illness results when there is disharmony within the body. Therefore, the goal of the Oriental medicine physician is to restore harmony in the patient. This can be accomplished by using techniques such as acupuncture, moxibustion, and administration of herbal preparations. CONCLUSIONS: The underlying assumptions, diagnostic techniques, and treatments used by traditional Oriental medicine physicians can seem strange to Western-trained physicians, but they have proved efficacious for the treatment of patients over many millennia.

Eye Diseases↗

Becoming a holistic thinker: training effect of oriental medicine on reasoning.

The authors hypothesized that training in Oriental medicine would make students think in a more holistic way. Study 1 found that students of Oriental medicine exhibited a cyclic expectation of future change, a key characteristic of holistic thinking, more than did students in other majors, such that the former, not the latter, believed that if something was going up or going down, it would reverse its direction in the future. Study 2 found that students in Oriental medicine also possessed a more complex causal belief and hence considered a greater amount of information in causal attribution than did students in other majors. More important, such a complex causal belief increased with the length of training in Oriental medicine. Implications and future research are discussed.

Adult↗

Screening of vasorelaxant activity of some medicinal plants used in Oriental medicines.

Hexane, ethylacetate (EtOAC), and n-butanol (n-BuOH) extracts of medicinal plants traditionally used in the East Asia, such as China, Korea, and Japan were screened for their vasorelaxant activity using isolated rat aorta. Among the 60 solvent-extracts from 20 medicinal plants, hexane and n-BuOH extracts of Diospyros kaki and Polygonum aviculare, hexane, EtOAC, and n-BuOH extracts of Magnolia liliflora, n-BuOH extract of Sorbus commixta, and EtOAC and n-BuOH extracts of Selaginella tamariscina were found to exhibit distinctive vasorelaxant activity. The activity disappeared by removal of functional endothelium or pre-treatment of the aortic tissues with N(G)-nitro-L-arginine methyl ester (L-NAME), which is an inhibitor of nitric oxide synthase. These findings suggest that the medicinal plants relax vascular smooth muscle via endothelium-dependent nitric oxide. These results will be useful to further analyze those medicinal plants that contain the vasorelaxant activity in order to identify the active principles.

Animals↗

[Stress in traditional Oriental medicine and clinical chemistry--from the viewpoint of salutogenesis].

The main methodology of modern medicine is pathogenesis, and that of traditional Oriental medicine, complementary and alternative medicine, and mind-body medicine is salutogenesis. Health in pathogenesis is an absolute idea, and health, disease, and death are separate. However from the viewpoint of salutogenesis, the human condition in pathology progresses continuously from health to disease (functional, organic and fatal one) to death, and in each level the subject can create relative health according to the condition. The evaluation of stress consists of evaluating wear-and-tear and the repair and restoration of the body. The general adaptation syndrome, 17-KS-S(S), 17-OHCS (OH), the S/OH ratio, and traditional Oriental medicinal evaluation are clearly related. It may be said that medical care in the new era (comprehensive medicine) consists of pathogenesis by modern medicine, salutogenesis by traditional Oriental medicine, complementary and alternative medicine and mind-body medicine, and the patient's individual autonomy (self-determination by self-responsibility).

Health↗

[The academic trend of Oriental medicine during the Japanese colonial period as observed through the publication of medical books].

This thesis examines the academical trend of Oriental Medicine in the Japanese colonial period observed through medical books published during the Japanese colonial period. This is a period in which Western Medicine was introduced, and due to the lean-to-one-side policy by the Japanese, Western Medicine became the mainstream medical science while Oriental Medicine was pushed to the outskirts. Even after all this, the academic activity was flourishing during this period compared to any other periods. This article is divided into various chapters each with its own theme in order to understand the academic trend of Oriental Medicine during the Japanese colonial period. Focusing on the publication of medical books, this article is divided and observed according to various themes such as the study of Dong-Eui-Bo-Gam (see text), the study of Bang-Yak-Hap-Pyeun (see text), the study of Sang-Han-Ron (see text), the study of Sa-sang (see text) constitutional medicine, the study of Eui-Hak-Ip-Mun (see text), the study about Bu-Yang-Ron (see text), On-Bo-Ron (see text), and pediatrics, compromise between Western and Oriental Medicine, the study of experience medicine, the study of acupuncture and moxibustion, and etc.

Books↗

[A study of the licensing system in Korean Oriental medicine].

In 1952, the Licensing System of Korean Oriental Practitioners was established by law and practiced until now. It was the most important aspect of the Professionalization of Korean Oriental medicine, and it also affected other aspects of the Professionalization of Korean Oriental medicine, such as the standardization of knowledge, the strengthening of its organization, and the development of an occupational ideology. The Licensing System of Korean Oriental Practitioners came about as a result of conflicts between the National Assembly, governmental agencies, and medical doctors. The range of Korean Oriental Practitioners Licensing is partially limited, especially with respect to certifying someone as a public health doctor and in conferring the right to direct medical technicians. However, the limitations have been reduced gradually.

History, 20th Century↗

Oriental medicine: an introduction.

This article covers introductory concepts regarding Oriental medicine, its historical context, yin and yang principles, and Five-Phase theory. It discusses organ theory, patient examination, diagnosis, the meridian network system, and treatment modalities such as acupuncture and Chinese herbal medicine, giving a brief overview of the different acupuncture and Oriental medical styles practiced in the United States. Included also are helpful tables, graphs, and photographs to provide a better visual context for Oriental medicine.

Acupuncture Therapy↗

A theoretical analysis of oriental medicine, 1: Acupuncture.

In spite of its long history, oriental medicine has been little understood, and therefore poorly accepted, by the Western mind. In order to penetrate beyond the veil of its jargon, a theoretical analysis of the fundamental tenets of acupuncture is given here, using concepts and symbols of modern science to elucidate phenomena of everyday practice. Thus, when Chi, Yang, and Ying are regarded as 'phased flows of bio-electromagnetic energy', intuitive comprehension should be facilitated. This novel approach has not, to the author's knowledge, been applied previously to any aspect of the medicine of the 'mysterious East'. A similar approach will be used to explore Kampo diagnosis/therapeutics and other selected topics in later papers.

Acupuncture Therapy↗

The arterial pulse analyzer as a potential replacement for manual pulse palpation in Oriental medicine.

Application of the arterial pulse analyzer now makes it possible to automatically diagnose such geriatric disorders as arteriosclerosis by using simple electrocardiograms and radial, carotid and posterior tibial artery pressure pulse wave charts. If the arterial pulse analyzer is adopted for use in Oriental medical clinics, there will no longer be a need for manual pulse palpation. In brief, applying the arterial pulse analyzer to the 8 key pulses of Oriental medicine yields the following results: 1) 'Slow' or 'rapid' pulses can be defined by the S-S interval (almost identical to the R-R interval of the ECG). 2) 'Slippery' or 'hesitant' pulses can be defined by the S-P time and the Dh/Ch% (P time & Incisura) ratio. 3) 'Floating' or 'submerged' pulses can be defined by the Ph/Ch% (pressure pulse wave to height) ratio. 4) 'Scattered' or 'moderate' pulses can be defined by the S-C- time (E time). Thus, by employing the arterial pulse analyzer, subjectivity problems inherent in the manual pulse palpation used by Oriental medicine for over 1500 years can be analyzed objectively.

Arteriosclerosis↗

Powerful hepatoprotective and hepatotoxic plant oligostilbenes, isolated from the Oriental medicinal plant Vitis coignetiae (Vitaceae).

The methanol extract of the Oriental medicinal plant Vitis coignetiae (Vitaceae) showed hepatoprotective activity in the in vitro assay method using primary cultured rat hepatocytes. Activity-guided fractionation of the extract afforded epsilon-viniferin as an active principle. The protective effect of epsilon-viniferin against mice carbon tetrachloride-induced hepatic injury in mice was shown by serum enzyme assay as well as by pathological examination. In addition to epsilon-viniferin, plant oligostilbenes, ampelopsins A, C, F and the mixture of vitisin A and cis-vitisin A were also present in the extract. Among them, ampelopsin C and the mixture of vitisin A and cis-vitisin A were found to be powerful hepatotoxins.

Animals↗

Glycoproteins contained within Soamsan, a traditional Oriental medicine, are the main class of active ingredients responsible for the medicine-induced immune stimulation.

In our previous study, Soamsan, a traditional Oriental medicine, was shown to enhance the induction of antigen-specific immune responses, and it was speculated that the enhancing activity might be closely associated with glycoproteins contained within the medicine. To elucidate this speculation, protein samples from each component, used in the preparation of Soamsan, were obtained and their immune stimulating activities were tested with mouse splenocytes. All the samples markedly enhanced the lymphocyte proliferation and cytokine secretion by the mouse splenocytes. In particular, the enhancement was significantly higher with the protein sample treatments than with those of the original crude sample. Furthermore, the pronase E- and NaIO4-mediated inhibition of splenocyte-stimulation activity of the protein samples clearly supported that glycoproteins are the main class of active ingredients responsible for the lymphocyte stimulating activity of the samples. Consequently, our findings suggest that glycoproteins might have a pivotal role in Soamsan-mediated immune modulation, although the in vivo effect of the glycoproteins should be further elucidated.

Adjuvants, Immunologic↗

Panaxynol, a polyacetylene compound isolated from oriental medicines, inhibits mammalian lipoxygenases.

Panaxynol is a polyacetylene compound isolated from commonly used oriental medicines, and its effects on various cyclooxygenases and lipoxygenases were investigated. The compound had only a marginal effect on cyclooxygenase activities (IC50 values >> 100 microM), but inhibited lipoxygenases; 5-lipoxygenase (IC50, 2 microM), two isoforms of 12-lipoxygenase (leukocyte-type, 1 microM; platelet-type, 67 microM) and 15-lipoxygenase (4 microM). Thus, panaxynol inhibited leukocyte-type 12-lipoxygenase much more effectively than platelet-type 12-lipoxygenase. Falcarindiol, an analogue of panaxynol, inhibited these lipoxygenases with higher IC50 values than panaxynol. These compounds could provide a clue to develop a selective inhibitor of one isoform of 12-lipoxygenase.

Alkynes↗

Emphasizing a preventive medicine orientation during primary care/family practice residency training.

In the wake of managed care, primary care physicians are expected to be gatekeepers in the overall healthcare system. As such, preventive medicine, rather than disease-oriented medicine, will play a key role in keeping medical costs in line. To that end, the authors review the current preventive medicine practices and guidelines and suggest ways in which these practices can be implemented in the training of primary care/family practice residents.

Family Practice↗