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Results for “MALARIA/immunology”

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At least 19 recordsLinked to original sources
PubMed1962

Antibody production in human malaria as determined by the fluorescent antibody technique.

No reliable serological test has been available in the past to follow the course of antibody production in malarial infections. The indirect method of immunofluorescence was utilized in this investigation to study antibody response to sporozoite-induced Plasmodium vivax infections in two human volunteers. Malarial antibody was demonstrated approximately 3 weeks after infection, and has persisted thus far for 121 days. These preliminary results suggest that this method of serological testing is specific and provides a sensitive means of titrating antibody produced in malarial infections.

Animals↗
PubMed1960

The relationship of serum gamma-globulin concentration to malaria and sickling.

The serum protein patterns of groups of Nigerians including 98 children partially protected by "daraprim" against malaria, and 113 unprotected children, have been studied. The protected children have a significantly lower concentration of serum gamma globulin than the unprotected children from the age of 12 months onwards. In children, sicklers have a significantly higher serum gamma globulin than non-sicklers. It is suggested that sickling protects against malaria by enhancing the antibody response against the malaria parasite.

Anemia↗