AHA will own library materials.
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A new library building at the University of California Medical Center, San Diego provides 7,100 net square feet, seating for 100 readers, and a stack capacity of 23,000 volumes. The building contains three split-level floors with conventional reference and circulation services, a combination of group and single seating, rapid copying machines, audiovisual facilities, a public elevator, and an electronic security system for the protection of library materials. The library, intended primarily for the use of health care professionals and students in their third and fourth years of medical school, serves a teaching hospital and its associated research facilities.
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BACKGROUND: Aspergillus fumigatus, a ubiquitous fungus, is responsible for a number of lung disorders in atopic and non-atopic individuals. Standardized, pure, and relevant allergens are desirable for reliable immunodiagnosis of the disease and to understand the structural and functional properties of these allergens and the role they play in causing ABPA. OBJECTIVE: Molecular cloning and characterization of a relevant allergen from A. fumigatus cDNA library. MATERIALS AND METHODS: A cDNA library was constructed from 96 h old mycelium of A. fumigatus using lambda ZAP expression vector. A novel gene encoding an A. fumigatus allergen was identified by screening the library with sera from ABPA patients. The gene was cloned and the allergen over-expressed in Escherichia coli. This recombinant allergen, Asp f 16, was evaluated in ELISA and Western blots using sera from patients and normal subjects and peripheral blood mononuclear cells (PBMC) for antigen-induced stimulation. RESULTS: Seventy percent of the patients with ABPA demonstrated high levels of serum IgE antibodies to Asp f 16, a 43-kDa protein, whereas patients with allergic asthma, Aspergillus skin test-positive asthmatics without clinical evidence of ABPA, and normal controls failed to show Asp f 16-specific IgE binding by ELISA. The deduced amino acid sequences of Asp f 16 showed extensive sequence homology to 30.6-kDa Asp f 9 at the N-terminal region of the protein. PBMC from the majority of patients with ABPA exhibited significant proliferation with the recombinant Asp f 16 allergen. CONCLUSION: Specific humoral and cell-mediated immune responses of Af-sensitized patients against Asp f 16 suggest its usefulness in the immunodiagnosis of hypersensitivity diseases due to Af and understanding the pathophysiology of ABPA.
The public library system is targeting the geriatric population and instituting programs to meet informational and recreational needs. From retirement planning, visual aids, and screening, to accessing library material to the elderly, the public library system attempts to meet the challenge of providing service to this special population. Although not a formal group, the library has inherent therapeutic effects that benefit the elderly who participate in their programs. The clinician would be advised to take advantage of these various programs. Because each local and regional center will offer different programs, calling a local library is the most effective way to find out what a specific public library system has to offer. Nurses may also consider joint efforts to initiate programs in their library systems to better meet the population's needs.
The increasing expectation for easy, yet full remote access to library materials necessitates innovative thinking on the part of libraries. Other traditional methods of providing access don't always meet the needs of the library or the patrons. This paper describes the project of one library to develop a Virtual Desktop, making access easy to grant or withhold, and also making available a wider array of resources.
Conflicts can occur between the principle of freedom of information treasured by librarians and ethical standards of scientific research involving the propriety of using data derived from immoral or dishonorable experimentation. A prime example of this conflict was brought to the attention of the medical and library communities in 1995 when articles claiming that the subjects of the illustrations in the classic anatomy atlas, Eduard Pernkopf's Topographische Anatomie des Menschen, were victims of the Nazi holocaust. While few have disputed the accuracy, artistic, or educational value of the Pernkopf atlas, some have argued that the use of such subjects violates standards of medical ethics involving inhuman and degrading treatment of subjects or disrespect of a human corpse. Efforts were made to remove the book from medical libraries. In this article, the history of the Pernkopf atlas and the controversy surrounding it are reviewed. The results of a survey of academic medical libraries concerning their treatment of the Pernkopf atlas are reported, and the ethical implications of these issues as they affect the responsibilities of librarians is discussed.
An international program in health professions training has involved the development of a teaching materials library by teams of African faculty authors and U.S. instructional materials specialists. Communications difficulties and differences in culture and technology have made it necessary that the instructional designers develop new production and management strategies, in order to meet program objectives and to assure the quality of the teaching materials. These strategies would seem to have continuing applications to domestic as well as international instructional development programs.
In July 1981, the Planetree Health Resource Center opened on the San Francisco campus of California Pacific Medical Center (Pacific Presbyterian Medical Center). Planetree was founded on the belief that access to information can empower people and help them face health and medical challenges. The Health Resource Center was created to provide medical library and health information resources to the general public. Over the last twelve years, Planetree has tried to develop a consumer health library collection and information service that is responsive to the needs and interests of a diverse public. In an effort to increase accessibility to the medical literature, a consumer health library classification scheme was created for the organization of library materials. The scheme combines the specificity and sophistication of the National Library of Medicine classification scheme with the simplicity of common lay terminology.
A program for the interactive selection of potential starting materials given a desired target molecule is described. The program uses hierarchical search to rapidly select candidates from a large starting material library and contains a function to evaluate the appropriateness of the functionality of the starting material. The user can specify restrictions on features such as the number of atoms in the starting material, price limitations, chirality, and whether to use superstructure or substructure searching. Several examples of the results of the program are presented.
The new Health Sciences Library at the State University of New York at Buffalo is a harmonious and functional blend of the old and the new. The old is a renovated Georgian style building with formal rooms containing fireplaces, carved woodwork and English oak paneling. The new is a contemporary four-story addition. Through the arrangement of space and the interior design, the new library offers users easy access to services and resources; accommodates the heavy daily flow of users and library materials; provides an environment of comfort, quiet, and safety; and promotes efficient communication among all segments of the library staff. This was accomplished through sound architectural design which included close consultation with the library director and staff during the planning process. The new library is equipped to face the challenge of meeting the needs of biomedical education, research, and clinical programs of the institution and its constituents in the years to come.
Budgeting is a responsibility faced by all hospital librarians. Hospital administrators expect the librarian to present a financial plan for the year ahead. The budget must predict expenditures for personnel, library materials, purchased services, and equipment. The current and previous year's financial outlay should be coordinated with the budget year. To present a budget effectively, a librarian must relate financial requirements to goals of the institution of which the library is a part.
Collection management of library materials about alternative medicine may be a growing problem for librarians because differing views exist regarding the acceptability of this information in a public forum. The purpose of the study reported was to investigate possible differences in the views of physicians, medical students, and librarians regarding the availability of information about alternative medicine for both medical students and the general public. Interviews were conducted with two representatives from each group, all of whom are affiliated with the Faculty of Medicine at The University of British Columbia or its library. The study was exploratory in nature, conducted in part to determine whether a larger research project in this area should be mounted. The data revealed considerable differences in opinion about alternative medicine: the librarians were more hesitant about the acceptability of radical or revolutionary materials, particularly those containing information that could result in direct harm to a patient. The physicians and medical students were more confident than the librarians that traditional medical treatment (and therefore information about it) should always be paramount.
Combinatorial catalysis is the systematic preparation, processing, and testing of large diversities of chemically and physically different materials libraries in a high-throughput fashion. It also embodies microfabrication, robotics, automation, instrumentation, computational chemistry, and large-scale information management (informatics), and as such carries the promise of a renaissance in catalytic reaction engineering. Significant progress has already been made in demonstrating the speed and economic advantage of combinatorial approaches by the discovery of superior catalytic materials in a matter of hours and days, as opposed to the months and years required using traditional methods. Combinatorial methods can also significantly contribute to our understanding of catalytic function by increasing our chances of discovering totally new and unexpected catalytic materials, and by expediting the recognition of trends and patterns of structure-activity relations, from which new catalytic materials can be designed more efficiently. Combinatorial catalysis undoubtedly will be the new paradigm of catalysis research as the industry faces increasing global competition and pressure for the development of environmentally friendly processes at a time when resources for research are diminishing.
Two U.S. Supreme Court decisions, O'Connor v. Donaldson and Bounds v. Smith, hold important implications for health sciences librarians serving in mental health facilities. The first, O'Connor, with its many ancillary holdings, puts mental health personnel on notice that patients have certain basic rights, which courts all over the country will now be required to enforce. In Bounds the court has ruled that prison authorities must assist prison inmates in preparing and filing legal papers. The ruling will most likely benefit all mentally disabled prisoners, and future litigation may expand this category to include: (1) persons committed under the criminal code, (2) persons under involuntary commitment not related to the criminal code, and (3) persons voluntarily committed. A selective annotated bibliography, consisting of background readings in mental health and the law, basic rights, law library materials, and mental health legal services, has been compiled to help librarians establish and develop legal collections in anticipation of court decisions that will expand the conditions of Bounds to include all mentally disabled patients.
OBJECTIVES: Clinical decision-making in the intensive care setting frequently requires the physician to obtain additional resource information. Physicians typically consult with colleagues, use personal medical books or files, or use library materials. Clinical librarians may also be used. This study evaluates the effectiveness of an ongoing clinical librarian program in the intensive care setting. DESIGN/SETTING: During a 3-month period, house officers in the medical and coronary ICUs in a major teaching hospital asked the clinical librarian 66 patient-care questions. Attached to the information selected by the clinical librarian was a questionnaire asking how the information was applied. MAIN RESULTS: There was an overall response rate of 65.1%. House officers indicated that the information: a) aided in diagnosis (37.2%), b) contributed to a better understanding of the therapy (51.2%), and c) resulted in improved patient management (30.2%). In some instances, the information was multibeneficial. The clinical librarian spent an average of 47 mins/question, and accumulated an average computer charge of $3.59. Personnel and on-line charges over the 3-month study period averaged $45/question. CONCLUSIONS: Clinical librarian programs may deliver patient-specific information in a timely, cost-effective manner. This information has an impact in the intensive care setting.