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At least 19 recordsLinked to original sources
PubMed1986

Effect of controlled exercise on libido in 2-yr-old stallions.

Eight sexually inexperienced, 2-yr-old Morgan stallions were used in a consecutive two-phase design with two groups of four stallions each. Each phase lasted 16 wk, with semen collections every 14 d. Libido scores were assigned to stallions during each semen collection. Scores ranged from zero to four, with zero indicating minimum and four representing maximum libido. In Phase 1, four stallions received daily forced exercise for 16 wk, and the remaining four stallions were confined to box stalls. In Phase 2, the previously exercised stallions were confined to box stalls, and the non-exercised stallions of Phase 1 received daily forced exercise. No week X treatment effect (P greater than .05) was found in Phase 1. Exercised stallions, however, tended to have lower libido values than non-exercised stallions from wk 10 through wk 16. A week X treatment effect (P less than .01) was found in Phase 2. Libido scores were lower (P less than .05) over time among exercised stallions, whereas scores of non-exercised stallions tended to remain stable or rise slightly over time. Mean libido scores for exercised and non-exercised stallions were different (P less than .05) at the end of Phase 1 (2.06 +/- .37 and 3.5 +/- .37, respectively). By wk 26, mean libido scores were similar (exercised: 2.62 +/- .34; non-exercised: 2.52 +/- .34). However, by wk 32, libido values for exercised stallions were lower (P less than .05) than non-exercised stallions (1.87 +/- .34 and 2.81 +/- .34, respectively). In general, mean libido scores of the non-exercised group were higher than exercised stallions after 12 wk of forced daily exercise.

Animals↗
PubMed1976

[Disorders of libido from the gynecological view point].

Sexual dysfunctions are differentiated according to the following symptoms: libido dysfunction, orgasmic dysfunction, vaginism, algopareunia and polysymptomatic dysfunction. In the out-patient service for sexual and other psychosomatic disorders of the University of Heidelberg's Women's Hospital 90 women with libido dysfunction were treated with conflict-centered psychotherapy after exclusion of organic diseases which could explain the reduction of libido and after exclusion of a depression where the loss of libido is a regular symptom. The success-rate was 63%. It was attempted to reinforce the ego of the patient which enables him to experience his surroundings with less conflicts. Neurotic anxieties and symptoms are decreased and loos their importance so that the patient is able to handle his sexual disturbance. Among the psychosocial factors, i.e. focal causes, responsible for the libido dysfunction we found: In 48% of the cases the relationship between parents and children had been disturbed, which caused difficulties in the identification process (lack of father or mother, cool mother, divorce, borken home). Problems with the partners were found in 42%. 2/3 of these women had not grown up in intact families, which seems to predestinate difficulties in communication later on. Psychodynamically the loss of libido means sexual resistance which can lead to aversion or disgust. When there is no excitement the vasocongestion and lubrication do not take place: cohabitation pain (algopareunia) results. On the other hand the reduction of libido can also be a result of chronic algopareunia, i.e. secondary. Psychogenic bleedings ("aversion-bleeding") during or after intercourse occasionally occur in combination with algopareunia and lack of libido.

Dyspareunia↗
PubMed1989

The non-significant effect of feeding level, growth rate and age on libido of young Afrikaner bulls.

Afrikaner bulls (n = 30) between 9,5 and 15 months old, were allocated to 2 dietary treatments fed ad libitum. Diet 1 consisted of 70% concentrate and 30% Eragrostis curvula hay (11,4 MJ ME kg-1 DM) and Diet 2 of 40% concentrate and 60% E. curvula hay (9,3 MJ ME kg-1 DM). Five libido tests were conducted per bull between the ages of 16 and 28 months. Bulls were pre-stimulated for 10 min by close contact with previously synchronised oestrous heifers. Three bulls were then simultaneously allowed a period of 15 min with 6 heifers. Manifestations of libido were indexed as follows: 1. smelling heifer and definite signs of interest; 2. attempt to mount without erection; 3. mount with erection but no intromission; 4. successful service. Libido values fluctuated highly both within and between bulls. Libido did not improve over the 16 to 28-month age period nor with experience as successive tests were conducted. Bulls on Diet 1 grew significantly faster during the first 7,5 months of the trial, but demonstrated non-significantly higher libido scores. It was concluded that maturation over the 16 to 28-month age period, learning experience and level of feeding had no effect on libido.

Age Factors↗
PubMed1990

Libido, hormone concentrations in blood plasma and semen characteristics in Holstein bulls.

Relationships among bull libido, serum hormone concentrations and semen characteristics were studied using 18 Holstein bulls that were 4 to 5 yr old. The hormones studied included testosterone, estradiol (E2), prolactin (PRL), LH and cortisol. Two ejaculates were collected three times per week from each bull during a 5-wk trial. During the last week of the trial, on a day semen was not collected, blood was collected from indwelling catheters every 15 min for 6 h to determine the hormonal profiles of each bull. On the following day, blood was sampled every 10 min before and after the time of semen collection. Libido factors were quantified, and semen volumes and sperm concentrations were recorded. The libido factors included reaction time to first service, latency time between the first and second semen collections, and duration of time the bull mounted the teaser prior to the first (TM1) and second (TM2) semen collection. Average reaction and latency times were correlated (r = .524; P = .026), as were TM1 and TM2 (r = .597; P = .015). Latency times were correlated with average TM2 (r = .669; P = .003). Average PRL concentrations were correlated with average latency times (r = .467; P = .05). Low libido bulls tended to have higher E2:testosterone ratios than did high libido bulls. Both PRL and cortisol concentrations increased at semen collection.

Animals↗
PubMed1990

Short-term individual housing temporarily reduces the libido of bulls.

The objective of the present study was to determine the effects of short-term (6 wk) individual housing on the sexual interest (libido) of sexually experienced bulls. Twenty-two Hereford bulls reared with both males and females (BMF) or in all-male groups (BM) and approximately 21 mo of age were given free access for 40 min to five restrained females in hormonally-induced estrus and restricted access for 30 min to a single enclosed estrous female on two separate occasions. Free-access tests were administered to bulls in groups of five or six individuals, whereas bulls were tested individually in restricted-access tests. After testing, half the animals were housed individually (physically isolated from conspecifics) and half remained in group housing for a 6-wk period. Libido tests were administered again at the end of the treatment period and 2 wk after reinstatement of group housing for the experimental subjects. Individually housed bulls exhibited fewer mounts (P less than .001) and spent less time with females (P less than .01) in tests administered during physical isolation than before or after treatment. Individual housing did not affect BMF and BM bulls differentially. In conclusion, short-term individual housing temporarily reduced libido of beef bulls.

Aggression↗
PubMed1986

The effect on fertility, libido and sexual function of post-operative radiotherapy and chemotherapy for cancer of the testicle.

Forty-six patients treated with post-operative radiotherapy and/or chemotherapy for cancer of the testicle were investigated to study the effect of this adjuvant treatment on fertility, potency and libido. In general, no change occurred in either libido or potency, even when the remaining testis was atrophic. The post-operative treatment was the cause of sterility in 17 patients known to be previously fertile. An atrophic testis after treatment denotes irreversible sterility. Current methods of shielding to protect the normal testis using a cobalt beam are unsatisfactory, and consideration should be given to treating all such patients on a linear accelerator. When normal fertility is retained there is no contraindication to parenthood. No evidence of increased abnormality has been found in any baby born to a man treated for testicular cancer.

Combined Modality Therapy↗
PubMed1991

Combined administration of a gonadotropin-releasing hormone antagonist and testosterone in men induces reversible azoospermia without loss of libido.

GnRH antagonists suppress pituitary and gonadal function by competing with endogenous GnRH for binding to receptors on pituitary gonadotrophs. We studied the effects of GnRH antagonist administration to men in a protocol simulating a likely male contraceptive regimen combined with a low dose of testosterone. The GnRH antagonist Nal-Glu was given daily (10 mg, sc) for 20 weeks to eight normal men, and a low dose of testosterone enanthate (25 mg, sc) was given every week. Sperm counts started declining during week 4, and complete azoospermia was reached within 6-12 weeks in six of the eight subjects. Subjects 7 and 8, whose sperm counts and serum gonadotropin levels were not suppressed after 10 weeks, were given 20 mg Nal-Glu starting at week 10. One became azoospermic at week 16, while the other's total sperm counts continued declining and reached a nadir of 1.4 million by week 20. Sperm motility and viability in this subject were completely suppressed after week 14. Sperm counts returned to baseline levels 12-14 weeks after the end of Nal-Glu administration. The mean serum LH level of the first six subjects decreased from 3 +/- 03. U/L at baseline to less than 0.1 U/L until week 20, and then levels returned to baseline. FSH levels similarly decreased from a combined mean of 3.6 +/- 0.9 U/L at baseline to below 0.3 U/L after 4 weeks of Nal-Glu administration. Serum mean testosterone levels between weekly injections of testosterone enanthate ranged from 27.4 +/- 5.9 to 4.8 +/- 1.4 nmol/L, but remained in the hypogonadal range (less than 10 nmol/L) for 4 of the 7 days. None of the subjects, however, complained of decreased libido or potency, as assessed by a questionnaire. No systemic or significant local side-effects were observed, other than a minimal reaction at the injection site. These data suggest that complete sustained azoospermia can be achieved in man, without loss of libido, by chronic administration of a GnRH antagonist plus testosterone.

Adult↗
PubMed1979

Influence of exogenous testosterone on sperm production, seminal quality and libido of stallions.

The effect of exogenous testosterone on sperm production, seminal quality and libido was studied in 24 stallions. Based on pretreatment data, a stallion was assigned to 1 of 3 groups each containing 8 animals. One member of each group received 0 (Group 1), 50 (Group 2), or 200 micrograms (Group 3) testosterone propionate per kg body weight every 2 days for 88 days. The lower dose of testosterone had no significant effect on most of the parameters studied: the higher dose depressed total scrotal width at Day 90 post-treatment (P less than 0.01), total spermatozoa ejaculated between Days 60 and 90 (P less than 0.01) and 96 progressively motile spermatozoa between Days 60 and 90 (P less than 0.10). One half of the stallions from each treatment were castrated on Day 90. In the operated stallions, the mean number of spermatids per g testicular parenchyma in the controls (Group 1) was significantly (P less than 0.05) higher than that in Group 3 whereas the difference between the number of spermatids/testis in the same stallions of these two groups was significant only at P less than 0.1. Testosterone propionate treatment did not influence time to erection, interval from first mount to ejaculation or number of mounts per ejaculation. The treatment of normal, intact stallions with testosterone propionate did not enhance libido and caused a severe depression of reproductive capacity.

Animals↗
PubMed1988

Increased libido in three men treated with trazodone.

Two sexual side effects associated with trazodone have been reported: priapism in men and increased libido in women. This report describes three depressed men who had increased libido while receiving trazodone. Possible mechanisms are suggested. Research is needed to explore trazodone's usefulness in treating disorders of sexual desire.

Adult↗
PubMed1979

Decreased libido--a side effect of carbonic anhydrase inhibitor.

Thirty-nine cases of decreased libido in glaucoma patients on carbonic anhydrase inhibitors are reported. This symptom completely reversed or markedly improved after discontinuation of the drug in all cases. Twelve of these patients restarted their carbonic anhydrase inhibitor medication which resulted in a recurrence of decreased libido symptoms. There were 3 cases of impotency which reversed after discontinuation of the drug. Most likely, these symptoms are a result of the malaise and depression occurring in some patients on carbonic anhydrase inhibitor therapy.

Adult↗
PubMed1986

Increased libido in women receiving trazodone.

The author presents the cases of three depressed women whose libido increased to above premorbid levels during trazodone treatment. Two patients resisted discontinuing the drug because of this pleasurable side effect.

Adult↗
PubMed1987

Effect of bromocriptine on affect and libido in hyperprolactinemia.

Six women with primary hyperprolactinemia (mean prolactin level, 50 ng/ml) were matched with six normal women on eight factors influencing life style. Observers blind to endocrine status followed the subjects weekly for 10 weeks. Patients took bromocriptine, 2.5 mg twice daily, or placebo in a randomized double-blind sequence with crossover at 5 weeks. The mean Hamilton score for the patients was compatible with mild depression and higher than that for normal subjects during placebo but not during bromocriptine treatment. Libido was similar in both groups during placebo and bromocriptine. The mean number of orgasms reported per day was lower in patients than in normal subjects during both treatment conditions, although one patient reported orgasms during drug treatment only. Hyperprolactinemia in women may be associated with mild depression and a decrease in orgasmic frequency.

Adult↗
PubMed1992

Measures of libido and their relation to serving capacity in the ram.

The purpose of this study was to determine whether the ejaculation rate (serving capacity) of sexually experienced rams could be estimated by selected measures of sexual libido when rams were exposed to estrous ewes under conditions that prevented copulations. Twenty-four crossbred rams selected for either high or low rates of copulation were exposed to two restrained estrous ewes under three treatment conditions that 1) permitted the full range of precopulatory and copulatory behaviors, 2) permitted precopulatory behaviors and mounting but precluded copulation, or 3) permitted precopulatory behaviors but not mounting or copulation. Frequencies of precopulatory behaviors (bouts of leg-kicking and anogenital sniffing) in each of the three treatment conditions and mounting frequency in Treatment 2 occurred in proportion to the ram's characteristic ejaculation rate (P < .001), suggesting that the mating potential of rams can be estimated under conditions that preclude copulation. Frequencies of precopulatory behaviors and mounting were lower when the rams were allowed to copulate, due largely to periods of sexual inactivity after ejaculations.

Animals↗
PubMed1976

Testosterone and libido in holstein bulls of various ages.

Testosterone was measured by radio-immunoassay in the blood plasma collected from 197 and 195 Holstein bulls in the spring and fall seasons, respectively. Bulls ranged in age from 8 mo to 13.5 yr. The average value for spring was 8.0 ng/ml, higher than the value of 5.7 ng/ml in the fall. Also, there was a tendency for testosterone to increase with age of the bulls up to 6 to 7 yr. The concentration of circulating testosterone was unrelated to libido or semen quality.

Age Factors↗
PubMed1992

Alterations of libido in gased Iranian men.

This investigation was done on 800 Iranian men who survived the immediate hazards and lethal phase during chemical warfare exposure. At the time of interview they had gone back to their usual lives. Men injured with chemical weapons containing mustards may have impotency and loss of or decreased libido.

Chemical Warfare Agents↗
PubMed1989

Loss of libido.

Loss of libido is caused by unconscious anger and it can be restored if the feeling of anger is expressed. The common causes of such anger are classified and case histories suggest how the doctor/patient encounter can be used to help patients.

Adult↗
PubMed1987

Reversible sterility by cyproterone acetate plus testosterone enanthate in langur monkey with maintenance of libido.

Cyproterone acetate (1 mg/kg b.w. per day; oral) in combination with testosterone enanthate (2 mg/kg b.w. 15 days; i.m.) was administered for 60 and 90 days into adult male langur monkeys (Presbytis entellus entellus, Dufresne). Testicular weight and volume were reduced significantly. Spermatogenesis was suppressed but the interstitial cells appeared normal. Seminiferous tubules and Sertoli cell nuclear diameters were reduced significantly. The indices of testicular steroidogenesis, i.e. testicular total proteins, sialic acid, RNA and fructose showed a fall. On the contrary, cholesterol, total lipids, glycogen and phosphatases increased after treatment. Libido was not affected. Cessation of treatment resulted in a resumption of all the variables to normal levels within 90 days. The results reveal a reversible inhibition of testicular steroidogenesis which ultimately resulted in the disruption of spermatogenesis, a definite index of sterility. It is further emphasized that simultaneously administered testosterone enanthate maintains androgenicity.

Animals↗
PubMed1989

Libido, menopause, and estrogen replacement therapy.

Patients may be embarrassed to communicate their concerns regarding a decrease in sexual desire to their physician, let alone request treatment. Drs Beard and Curtis recommend that patients be asked specific questions to elicit symptoms of sexual dysfunction. They outline a program of hormone replacement therapy for women who have sexual dysfunction secondary to genitourinary atrophy and for those whose loss of libido is secondary to declining levels of estrogen.

Estrogens↗