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Results for “Lens Capsule, Crystalline”

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At least 19 recordsLinked to original sources

In vivo observation of the crystalline lens capsule.

The crystalline lens capsules of eye bank eyes, intraocular lens (IOL)-inserted eyes and those of monkey and rabbit eyes were observed in vivo and/or in vitro through a specular microscope or Scheimpflug slit images in combination with new image-processing techniques and scanning electron microscopy. Shagreen patterns seen in both human and animal eyes may reflect the lens epithelium and basement-membrane-like layer. As a postoperative examination in IOL-inserted eyes, the distance between the IOL and the posterior lens capsule could be measured with an accuracy of 50 microns.

Animals↗

[The biomechanical properties of the crystalline lens capsule in emmetropia and myopia].

Morphometric and electronmicroscopic studies of the capsule of a clear lens depending on the degree of myopia and age as compared with the capsule of a clear lens in emmetropia and myopia have shown that with age the anterior capsule of a clear lens becomes thicker, while the posterior capsule becomes thinner and increases in length. This is connected with the weakening of accommodation in the presence of different curvature of the anterior and posterior surfaces of the lens on the background of the lowering of the metabolic level in elderly persons. In myopia, with the development of age changes the thickness of the lens capsule remains almost unchanged. The degree of myopia doesn't influence the thickness and the length of the anterior capsule of the lens, while with the rise of myopia the thickness of the posterior capsules increases. No dystrophic changes in the structure of such a capsule in high myopia were revealed. Hypertrophy of the posterior capsule speaks about the increase of its mechanic strength in a clear lens and is connected with the weakness of accommodation. Such a capsule can serve as a support for IOL implants in patients with myopic refraction.

Adult↗

Crystalline lens capsule staining with trypan blue.

A 1-step method for staining the anterior lens capsule with trypan blue is described. The dye is instilled via a paracentesis port at the start of cataract extraction. As aqueous humor is allowed to exit the anterior chamber (AC), which consequently shallows, the resulting pupil block confines the dye to the AC. An ophthalmic viscosurgical device (OVD) is used to flush dye-stained aqueous from the AC, circumventing the need for AC washout. Although the OVD may be tinged with dye, this does not impede performing capsulorhexis. This method does not add to the surgical time, requires no additional instruments or materials, and is safe.

Capsulorhexis↗

[Comparative study of bovine ocular lens proteins in native tissue and an extract using the x-ray diffraction method].

It has been shown that the maxima (Bragg-spacings 4,5-19 A) on the X-ray diffraction patterns of the bovine lens native tissues from nuclear and cortical parts are predominantly due to the water-soluble crystallin intramolecular structure. The structures of water-soluble and water-insoluble fractions from bovine lens nucleus and cortex were qualitatively compared. Reversible dependence of the lens water-soluble protein structure on water content in the system was demonstrated.

Animals↗

Protein synthesis in x-irradiated rabbit lens.

The present study deals with the incorporation of 35S methionine into lens crystallins as a function of time after x-irradiation. Crystallin synthesis is first affected approximately 4 weeks following x-irradiation. This coincides with the time period at which the ratio of the two cations in the lens is affected, as shown in earlier studies. A greater decrease in 35S-methionine incorporation into crystallins is observed between 5-7 weeks following x-irradiation in good agreement with a cation imbalance at these time intervals. These studies also revealed for the first time that the change in cation distribution can affect not only crystallin synthesis, but also the synthesis of certain polypeptides of lens membranes. No alteration in protein synthesis could be detected in lens epithelium even after 7 weeks following irradiation. In addition to the effect of Na+ and K+ levels on protein synthesis, an impaired transport of amino acids into the x-rayed lens was also found to be a factor in the observed reduction in synthesis of the crystallin, cytoskeletal and membrane proteins of the fiber cells. It is concluded that Na+/K+ ratio as well as the availability of amino acids in the lens are important factors in protein synthesis of x-ray cataracts.

Animals↗

[Anterior capsulotomy using a diathermy cutter. Experimental principles (1)].

In experimental studies a new method for anterior capsulotomy of the crystalline lens was developed. The anterior lens capsule can be cut by diathermy in such a manner that this action can be reproduced. The effects of current are illustrated by means of light-microscopic sections, which are also helpful in estimating the degree of surgical trauma. Advantages of the new method are outlined and discussed, with references to other publications.

Animals↗

Perforation rosette of the lens after Nd:YAG laser iridotomy.

PURPOSE: To describe an unreported complication of Nd:YAG laser iridotomy. METHODS: We examined a 31-year-old patient with pigment dispersion syndrome and moderately increased intraocular pressure whose left eye had been treated prophylactically with Nd:YAG laser iridotomy and who complained of blurred vision thereafter. RESULTS: Slit-lamp examination of the left eye disclosed a typical perforation rosette of the posterior pole of the crystalline lens with a perforation of the anterior lens capsule under the iridotomy site and pigment within the lens. Opacity regressed spontaneously, and vision returned to normal. CONCLUSIONS: A perforation rosette of the lens can occur after Nd:YAG laser iridotomy and should be considered a possible serious complication of the procedure.

Adult↗

Induction of de novo synthesis of crystalline lenses in aphakic rabbits.

The mammalian lens, like other ectodermal tissues, can regenerate itself given the proper environment. Endocapsular phacoemulsification of adult rabbit lenses was performed. A lens capsular bag with posterior and anterior lens capsule relatively intact was left in the eye. Regrowth of material in the capsular bag was followed by slit lamp biomicroscopy and photography over a 12-month period. Histopathology of the new material showed regions of relatively normal epithelial cells and lens fibers as well as regions where growth was irregular. All major lens crystallin classes were present in the regenerated lens. Several specific crystallin subunits, known to arise by post-translational modification of primary gene products, were absent or present in abnormally low concentrations.

Animals↗