SEARCH · Search PubMed
Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.
Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.
The administrators of the only program of its kind in the US explain the demand for a Master's degree in Laboratory Animal Science, the value of the degree, and plans to expand the program to make it available for distance learning.
Explore the source record for details and available documents.
Changes in laboratory animal science in the 20 years since George Porter's death are reviewed, with particular emphasis on animal welfare. The need for a generally acceptable definition of animal welfare is emphasized and a new definition is propounded. The concept of stewardship as a basis for human-animal relationships is explored. This involves Man accepting his responsibility for his relationship with, and care of, animals while simultaneously accepting a moral responsibility to God, or others, for that care and relationship.
Explore the source record for details and available documents.
Students enrolled in the laboratory animal science graduate program at MCP Hahnemann University seek to gain entrance to veterinary school or to manage an animal facility within an academic institution, pharmaceutical or biotechnology company conducting biomedical research. Ongoing interaction between faculty in the radiation oncology, radiation safety, and lab animal science disciplines revealed an acute need for radiation safety education for laboratory animal science students who will likely interact with researchers either designing and writing protocols for animal studies using radiation or radioactive materials, or veterinary staff who will use sources of radiation to diagnose and/or treat possible animal injuries and diseases. A core course in the Radiation Sciences graduate program was modified to address the needs of these students, instructing them in radiation safety, detection and counting instrumentation, and radiation biology. These fundamental areas were integrated to help the students gain a sound, basic knowledge of radiation and radioactive materials used in biomedical research.
Explore the source record for details and available documents.
LABORATORY animals are considered to be an 'obscure' specialist area by many veterinary surgeons, despite the fact that the knowledge they apply in their daily work and all of the medicines they use depend on research or testing using laboratory animals. The employment of veterinary surgeons in research is a well known aspect of the profession. Less well known is the contribution made by veterinarians as toxicological pathologists, assessing the effects of new chemicals and pharmaceuticals on laboratory animals used in safety testing. But the most important contribution of the profession is as advisers on laboratory animal welfare and health. The British Laboratory Animals Veterinary Association (BLAVA) is a specialist division of the BVA dedicated to representing and educating the profession in this area. Since 1986 every research institute has had to employ a named veterinary surgeon to advise on the health and welfare of these animals and BLAVA has therefore grown to over 200 members. In this paper BLAVA sets out its vision of how undergraduate education could meet this challenge.
During the past 25 years tremendous improvements have been made in the field of laboratory animal science. Refinements in genetic and microbial quality assurance and animal housing coupled with the development of professional expertise has contributed to enhanced animal well-being and a reduction in the variability of data collected from research animals. These advances occurred concomitant with an increased public awareness of research animal use. In 1967 Laboratory Animals Ltd. published the first issue of Laboratory Animals. In celebration of its Silver Jubilee, I will briefly highlight some of the changes which occurred in the field of laboratory animal science since 1967 and some of the medical advances which depended on animal-based research.
A meeting was organised by the Laboratory Animal Science Association (LASA) Alternatives Section to provide a forum in which ideas for strategies to raise awareness of the Three Rs could be discussed. One of the main objectives of the meeting was to identify effective strategies which could feasibly be implemented at establishments. In general, there are two main ways in which Three Rs information can be obtained and communicated. Individuals can be assigned to a role with specific responsibilities (for example, a named alternatives expert), or committees can be established, with a remit to find ways to reduce, refine and/or replace animal use (for example, an alternatives committee). The meeting involved invited speakers who are engaged in obtaining and communicating Three Rs information, and this report presents a summary of the advantages and limitations of various approaches that are being undertaken.
There are a number of challenges facing young people planning their future with little but a love of animals to guide them. Pursuing a successful career in veterinary medicine can be a trying experience; there are a limited number of highly competitive academic programs, and even if one manages to enroll in such a program and complete the degree, there remains the daunting dilemma of whether to proceed directly to private practice, or whether instead to strike out on a new path and explore an alternative career in animal medicine. The eleven men and women profiled here are all respected figures from the laboratory animal science community, representing a broad cross-section of backgrounds and interests: genetics researchers, exotic species specialists, animal welfare advocates, nutritionists, facility managers, and so forth. Some worked their way through veterinary school and private practice before deciding on a radical career shift that brought them to where they are now, others started their careers in a laboratory, while others still followed a more indirect path, guided only by chance, curiosity, and a love of animals.All eleven, however, have each made their own unique contribution to the field, and Lab Animal has invited them to tell their own stories, in their own words, to illustrate some of the interesting, entertaining, and surprising turns a career in laboratory animal science can take.
Explore the source record for details and available documents.
Email lists can be invaluable for acquiring information that may not be easily accessible in the published literature. The author discusses the general format and functioning of email lists and describes six lists that can be valuable tools for education, training, and information exchange in the field of laboratory animal science.
The results from the analysis of the course evaluations from FELASA category C compulsory courses in laboratory animal science at Uppsala University showed that the students realize that theoretical knowledge of the subject and practical skills are of great importance to the success of their future research involving animal experiments. All the subjects and elements of the course, in particular the practicals on animal handling and procedures using live anaesthetized animals, were fully appreciated by the students.
Explore the source record for details and available documents.
The use of rodent models for research and testing on endocrine-active compounds necessitates an awareness of a number of laboratory animal science issues to standardize bioassay methods and facilitate reproducibility of results between laboratories. These issues are not unique to endocrine research but are particularly important in this field due to the complexities and interdependencies of the endocrine system, coupled with the inherently sensitive and variable nature of physiological endpoints. Standardization of animal models and the control of animal environments depend on the establishment of strong scientific partnerships between research investigators and laboratory animal scientists. Laboratory animal care and use programs are becoming increasingly complex and are constantly changing, fueled in part by technological advances, changes in regulations concerning animal care and use, and economic pressures. Since the early 1980s, many institutions have moved to centralization of animal facility operations concomitant with numerous changes in housing systems, barrier concepts, equipment, and engineering controls of the macro- and microenvironment. These and other changes can have an impact on animals and the conduct of endocrine experiments. Despite the potential impact of animal care and use procedures on research endpoints, many investigators are surprisingly naive to the animal facility conditions that can affect in vivo studies. Several key animal care and use issues that are important to consider in endocrine experiments with rodent models are described.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.