[Lymphedema: How should lymphedema not be treated? Operative treatment of lymphedema].
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Noninvasive complex lymphedema therapy (CLT), a technique of manual lymph drainage, compressive bandaging, and specific physical therapy exercises, has been utilized successfully to treat lymphedema in Europe and Australia. This paper reports the results of such therapy in 38 patients (16 females with arm lymphedema secondary to breast surgery, 18 patients with unilateral lower extremity lymphedema, and 4 individuals with bilateral leg disease) for 1 month. Reduction of edema averaged 73% among the patients with arm disease, and 88% among those with leg lymphedema; both reductions are statistically significant. Thirty patients have been followed for up to 1 year. During this period, their average reduction in lymphedema of 80% improved to 86%. We conclude that CLT significantly and safely reduces lymphedema. Reductions not only are maintained after the initial therapy but may increase in magnitude.
Segments of an inferior inguinal ganglion and of an external iliac (upper inguinal) ganglion were microscopically examined in 46 cases of bilateral primary lymphedema and 26 cases of unilateral primary lymphedema. The examination was performed bilaterally and comparatively to a set of ganglions unaffected by lymphedema, during the years 1974-1978. In all the lymph nodes originating from the patients with lymphedema important morphopathological alternations were noticed, chiefly consisting in fibrosis, fibrosclerosis, fat loading, hyalinization processes, giganto-cellular responses, etc., leading even to an aspect of cirrhosis, lympho-nodal pseudo-cirrhosis. These alterations were also found on the healthy side of the patients with unilateral primary lymphedema at the time of the microscopical examination. In the same patient clinical edema appeared in the following years. The degree of the morphopathological alterations was greater in the side of the greater edema and more peculiar in the cases of bulkier edema.
We treated 119 consecutive patients with lymphedema with complex lymphedema therapy (CLT). Lymphedema reductions after CLT averaged 62.6% in the 56 patients with one affected arm and 68.6% in the 38 patients with one affected leg. In the 23 patients with bilateral affected lower limbs, lymphedema volume decreased by 3,681 cm3 in the right leg and by 3,433 cm3 in the left leg. Due to its small number, the group with bilateral affected arms was not analyzed. After 36 months' follow-up, the average reduction increased to 63.8% in individuals with one affected arm and remained at 62.7% in those with one affected leg. For statistical analysis, the amount of reduction after CLT in the group with bilateral affected legs was considered to be 100%. During follow-up, the right leg was maintained at 99.59% of the initial reduction and the left leg improved to 120%. Patients who were compliant showed significant increases in lymphedema reduction, whereas noncompliant patients lost part of their initial reduction.
The inguinal-iliac lympho-nodal fibrosclerotic processes appearing in female patients with primary lymphedema bring about an obvious tendency of reduction of the circulatory flux in the afferent lymphatics at some distance from the lympho-nodal area: at the foot or at the shank. The inguinal lympho-nodal morphopathological alterations (examined in 72 cases of primary lymph-edema) were followed, by distal lymph stasis at the level of the foot and of the leg, without sensibly affecting the lymph flow in the thigh. These aspects of the lymph stasis adjacent to the lympho-nodal areas are striking in the patients with secondary lymphedema.
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Manual lymph drainage on an outpatient basis is safe, effective and produces low costs.
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INTRODUCTION: The aim of this retrospective study was to describe the main characteristics and treatment of male external genitalia lymphedema. PATIENTS AND METHODS: From 1987 to 2003, all patients seen in a single hospital for lymphedema of male external genitalia were included. For each patient, the following characteristics were recorded: primary or secondary lymphedema, cause of secondary form, date of onset of lymphedema, associated lower limb lymphedema, clinical signs, and complications. In the primary forms, lower limb lymphoscintigraphy was performed. Specific surgery was proposed in all cases of symptomatic lymphedema (circumcision, scrotum and/or penile cutaneous excision). RESULTS: Thirty-three patients with lymphedema of external genitalia (17 primary, 16 secondary) were recruited. Two primary lymphedema were congenital, one isolated. Mean age +/- SD of the onset of the 15 other primary genital lymphedema was 23.4 +/- 17.5 years, always after the appearance of lower limb lymphedema. Sixteen men had secondary lymphedema (bladder, prostate, or rectum cancer, Hodgkin or non-Hodgkin lymphoma, aorto-bifemoral bypass grafting, biopsy or curretage of inguinal nodes). Secondary genitalia lymphedema was not associated with lower limb lymphedema in two cases and, in the others it occurred 66 +/- 122 months after (n=11), at the same time (n=2) or before lower limb lymphedema (n=1). Clinically, we noted genitalia heaviness (n=31), lower limb lymphedema (n=30), vaginal hydrocele (n=13), impaired miction due to prepucial swelling (n=10), leakage of lymphatic fluid (n=10). Lower limb lymphedema was complicated by at least one erysipelas (n=20), spreading to the external genitalia (n=4). In primary forms, lymphoscintigraphy showed ipsilateral hypoplasia of inguinal nodes in lower limb lymphedema (n=14) and/or external genitalia backflow (n=7). Surgical treatment was performed in 17 cases (11 primary, 6 secondary) with good results after 21 months' median follow up (1 month-10 years). Two patients died of cancer. One secondary lymphedema improved spontaneously and one disappeared after withdrawal of lower limb pneumatic compression. DISCUSSION: Lymphedema of external genitalia is responsible for discomfort and local complications. Surgical treatment is the main procedure of this disorder.