Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Intradermal Tests”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1992

Yellow jacket allergy. Comparison of skin prick tests and intradermal tests with three different yellow jacket venom extracts.

The aim of the present study was to compare yellow jacket venom extracts from two different companies and to compare skin prick test (SPT) with intradermal test (IDT). IDT and SPT with yellow jacket venom (ALK and Pharmacia Reless) were performed on 54 yellow jacket allergic patients and 44 symptom-free volunteers. Venom was diluted to 300, 100, 10 and 1 microgram/ml for SPT and 10(0), 10(-1), 10(-2), 10(-3) and 10(-4) micrograms/ml for IDT, according to the manufacturers' instructions. Skin tests were performed on both forearms. Both extracts showed approximately the same relationship between sensitivity and specificity, but the Pharmacia Reless yellow jacket venom extract showed a 5-10 fold higher biological activity in both SPT and IDT. Thus yellow jacket venoms of ALK and Pharmacia Reless are not comparable in allergen activity at the same venom concentrations. Using extracts from the same company, SPT and IDT were comparable with regard to sensitivity and specificity at an allergen concentration 1000 times higher for SPT than for IDT.

Adolescent↗
PubMed1991

[Induction of humoral antibodies by a BHV-1 intradermal test].

An intradermal test for the diagnosis of BHV 1 (Intrakutantest Behringwerke AG) was applied to 53 nonvaccinated BHV 1-seronegative cattle aged 7 months to 8 years. Serologic blood testing performed subsequently using ELISA (Enzygnost-IBR/IPV, Behringwerke AG) and SNT revealed seroconversion in 24 of 45 animals without previous maternal antibodies. A second application of the intradermal test after these BHV 1-antibodies had declined, lead to a 'booster-effect' while a control group remained negative. Six of nine animals not affected by the first intradermal application of BHV 1-antigen, developed BHV 1-antibodies following the second intradermal test. Eight animals possessing maternal antibodies showed no serological response to the intradermal test at all. Present results strongly suggest an induction of humoral BHV 1-antibodies by the intradermal application of inactivated BHV 1. Consequently, the indirect control of BHV 1 infections, especially in cattle breeding farms, should be done exclusively by serological examination.

Animals↗
PubMed1978

Studies on bilharzial dysentery: the relation among the egg count, the number of bowel motion and the antibody titre and the relation between the schistosomal antibody titre as detected by indirect haemagglutination test and the size of the wheal area of the intradermal test.

The authors studied the relation among the egg count, the number of motions and the antibody titer in 185 patients suffering from bilharzial dysentery. They found that no significant relation between the level of antibody titre and the number of ova and also no relation between egg count and number of motions but a significant relation between the number of bowel motions and the level of antibody titre was recorded. An auto-immune mechanism in Schistosoma mansoni has also been shown in this work but it needs further proof. On the other hand two diagnostic tests were performed namely the intradermal test and the indirect haemagglutination test. The former gave 84% positivity while the latter gave 94% positivity. In comparing the wheal size of the intradermal test and the titre of haemagglutination, it has been found that the wheal increases in size with rise of the titre. Therefore the wheal size can roughly suggest the level of immunity of the patient.

Adult↗
PubMed1979

Intradermal test in contact allergy to metals.

Variations of intradermal test results were studied in a group of patients with clinically evident contact dermatitis and with the history suggestive of contact with metals and with negative patch tests reactions to the latter. The positive reactions obtained in several cases indicate that intradermal tests may reveal specific sensitivities, which patch tests using standard concentrations are not always capable of demonstrating.

Chromium↗
PubMed1978

A study of skin diseases in dogs and cats. V. The intradermal test in the diagnosis of flea allergy in dogs and cats.

A group of 143 dogs and cats with pruritic skin disease was tested by intradermal injection of a dilute whole cat flea extract. The test results were correlated with the clinical diagnosis (Table I, III), with previous or present findings of fleas on the animals (Table II, III), with the presence or absence of blood eosinophilia (Table IV), and, in animals with clinical flea allergy, with the histological findings in a skin biopsy excised from a clinically affected skin site (Fig. 1). The predictive value of a positive and a negative outcome of the test was assessed graphically by means of calculations described in the Appendix (Figs. 2, 3). It is concluded that the test is sufficiently specific to justify its use in animals where flea allergy is suspected but cannot be proved by routine clinical examination. The histological findings and the nature of the skin reactions suggest that a positive outcome of the test is indicative of an immediate, type I hypersensitivity towards components of the oral secretion of fleas and that this hypersensitivity is mediated by reaginic antibody which to some extent is produced by plasma cells located in skin areas where flea saliva is deposited.

Animals↗
PubMed1979

Intradermal testing in the diagnosis of acute anaphylaxis during anaesthesia--results of five years experience.

Intradermal testing has been used in the diagnosis of acute anaphylactic reactions during anaesthesia in 51 patients. Positive results occurred in 32 patients and confirmation was possible in 26. Only in one case did a combination of history and intradermal testing not give a diagnosis. Nine of the negative results were confirmed. Intradermal testing is of no value in the diagnosis of reactions to local anaesthetics or colloids but has great value in determining the cause of reactions due to induction agents or muscle relaxants if performed under controlled conditions. It is safe, and requires no expertise in performance or interpretation.

Acute Disease↗
PubMed1975

Nonspecific reactions with the intradermal test for hydatidosis in persons with other helminth infections.

A partially purified Echinococcus antigen solution, prepared by boiling hydatid cyst fluid, was used in the intradermal test for hydatid disease in a Peruvian population. An unexpectedly high rate of positive reactions and poor agreement with serological tests suggested the presence of some agent(s) which produced cross-reactions with Echinococcus granulosus antigens in the intradermal test. Testing of hospital patients infected with a variety of helminths demonstrated nonspecific reactions in persons with Hymenolepis nana, Taenia spp., and Fasciola hepatica infections, mixed parasitisms, and several non-helminth pathological conditions. The findings contraindicated the use of the intradermal test for epidemiological surveys of hydatid disease. It is pointed out that intradermal test positivity rates cannot be used as synonymous with infection prevalence and regional differences do not necessarily reflect differences in the prevalence of E. granulosus infection. The greater specificity of some serological tests favor their use for epidemiological purposes.

Antibodies, Heterophile↗
PubMed1992

A prospective study into the value of patch and intradermal tests in identifying topical corticosteroid allergy.

We have prospectively performed patch and intradermal tests on 105 consecutive patients, attending for patch testing, to determine the optimum method of screening for corticosteroid hypersensitivity. Patch tests with Pivalone and a corticosteroid series (all 1% in ethanol) detected all the patients with steroid sensitivity. However, intradermal tests were essential to exclude false positive reactions and detect all relevant steroid allergies in any individual patient.

Administration, Topical↗
PubMed1976

Intradermal testing after severe histamine reactions to intravenous drugs used in anaesthesia.

In a series of patients who suffered severe histamine mediated reactions to induction agents and muscle relaxants, intradermal testing enabled the drug involved to be distinguished. The correct use of intradermal testing to give reliable results is discussed and a protocol described. Prausnitz Kustner testing was of little help in confirming the results. A number of patients tested showed high levels of immunoglobulin G (IgG) and it is believed that IgG mediated anaphylaxis may be the mechanism responsible for reactions that have been previously described as anaphylactoid or direct chemical histamine release.

Adult↗
PubMed1978

Intradermal test with histamine in Schistosomiasis mansoni.

Histamine diphosphate was injected intradermally, at dilutions of 10(-3), 10(-4), and 10(-5), into 25 boys (10--12 yr old), and 25 men (20--30 yr old) with active schistosomiasis mansoni. A linear relationship between the mean area of the wheals and the logarithm of histamine concentrations was determined. Both equations (men and boys) were significant (P less than 0.05) but showed no difference between their regression coefficients. These findings contrast with those obtained with the intradermal test performed with Schistosoma mansoni antigens, in which skin response in men is significantly greater than in boys.

Adult↗
PubMed1977

Specific immunity in patients suffering from recurring warts before and after repetitive intradermal tests with human papilloma virus.

The specific humoral and cellular immunity of 22 patients with multiple or recurring warts was studied. After repeated intradermal tests, using an inactivated, purified viral antigen, the responses obtained could be classed into two groups. The first group (10 patients) was characterized immunologically by the acquisition of a specific cellular immunity and the appearance of circulating IgG antibodies, and clinically by a total regression of resolution of the warts two to three weeks after the final intradermal test. The second group (12 patients) was characterized immunologically by a weak or non-existent specific immune response, and clinically by the unmodified persistence of the warts.

Adult↗
PubMedDate not supplied

[Results of intradermal tests with toxoplasmin in a survey performed among mental patients admitted to the clinical surgical teaching hospital "10 de Octubre" in Havana].

Intradermal tests using toxoplasmin were performed among three hundred mentally handicapped patients admitted to the "10 de Octubre" Clinical-Surgical Teaching Hospital in Havana between 1976--1977 and 100 healthy subjects. A statistically significant difference between reactors among patients (54,7%) and reactors among healthy subjects (30,0%) was found. Results are compared to those from a similar paper performed in the Psychiatric Hospital of Havana in 1967. It is concluded that the higher the severity of affections the higher the percentage of reactors in the surveyed series.

Antigens↗
PubMed1978

Bovine experimental paracoccidioidomycosis intradermic test standardization.

Three intratesticulary inoculated bovines revealed to be susceptible to experimental paracoccidioidomycosis. The experimental infection was self limited with no tendency to dissemination during a follow up period of five months. The histopathologic lesions characterized by granulomatous inflammatory foci, associated or not to necrosis, were found in the testicles, spermatic cords and testicular tunicae. In some of both lesions types the yeast cells of P. brasiliensis were present. The experimental infection did not cure in a follow up period of five months. The immunological response either cellular or humoral were delayed in relation to what happens in other animal species. The three experimentally infected bovines were utilized for some standardization of the paracoccidioidin intradermic test. A type and dose of an antigen which gives a clear reading for the positive tests was determined. The humoral responses were detected mainly by the complement fixation reaction. It was not possible to demonstrate humoral antibodies by the agar immunodiffusion test.

Animals↗
PubMedDate not supplied

[Reactivity of the intradermal test with toxoplasmosis in schizophrenic patients].

A hundred schizophrenic patients admitted to the "10 de Octubre" Clinical-Surgical Teaching Hospital and 158 schizophrenic patients admitted to the Psychiatric Hospital, both in Havana, and 100 control healthy individuals who did not consume psychopharmacons were studied. They underwent intradermal tests with toxoplasmin. Differences in reactor percentages between patients and healthy individuals were statistically significative as it has been reported in the foreign medical literature. The highest percentage of reactors in the group admitted to the Psychiatric Hospital where most advanced schizophreniacs are found leads to the conclusion that the more severe the patient state the higher the frequency and intensity of test reactivity among patients. Other factors as the dwelling conditions, age and sex are analyzed.

Adolescent↗
PubMed1977

Evaluation of the indirect haemagglutination and intradermal tests on hydatid and nonhydatid cases.

Evaluation of the immediate intradermal (ID) test showed a direct relationship between nitrogen concentration and sensitivity. Antigens of low nitrogen concentration were less reactive but more specific. Intradermal antigens prepared from Echinococcus multilocularis can be used in Isfahan, Iran, for the diagnosis of E. granulosus in man. The ID delayed reaction was observed in a few patients who had positive immediate skin tests. Because of its high sensitivity, the indirect haemagglutination (IHA) test was preferred for the serologic diagnosis of echinococcosis. Based on the results outlined in their study the IHA test appears to offer good sensitivity, and the ID, with an antigen of low nitrogen concentration, good specificity.

Animals↗