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At least 19 recordsLinked to original sources
PubMed1977

Radiological findings in Yersinia ileitis.

Bacteriological and clinical studies of patients with acute retional ileitis indicate that numerous patients with this diagnosis have a benign ileitis of short duration, caused by Yersinia enterocolitica, whereas others develop chronic Crohn's disease. Yersinia ileitis has some clinical and radiological features in common with Crohn's disease, but the two conditions are basically separate. In Yersinia ileitis, three stages are apparent: (a) the nodular stage, lasting up to three weeks; (b) the edematous stage (4th-5th week); and (c) resolution, observed during the 5th-8th week. The radiological findings in 25 patients with Yersinia ileitis and their distinction from Crohn's disease are described.

Adolescent↗
PubMed1991

Isolation of an intracellular bacterium from hamsters (Mesocricetus auratus) with proliferative ileitis and reproduction of the disease with a pure culture.

An intracellular bacterium was isolated from hamsters (Mesocricetus auratus) with proliferative ileitis. The organism was isolated in Intestine 407 and GPC-16 cell cultures (incubated in a microaerophilic atmosphere) from isolated and lysed epithelial cells from hamsters with proliferative ileitis. The bacterium measured 1.4 to 1.7 microns in length by 0.26 to 0.34 microns in width, was slightly curved, and had an irregular trilaminar cell wall. Inoculation of hamsters with a cell culture lysate containing the organism or a 0.65-microns-pore-size filtrate of an infected-cell lysate resulted in the typical lesions of proliferative ileitis in approximately 50% of the animals in 28 days. Hamsters inoculated with uninfected cells or a 0.2-microns-pore-size filtrate of an infected-cell lysate remained uninfected. Attempts to propagate the organism on cell-free media have been unsuccessful.

Animals↗
PubMed1991

Yersinia terminal ileitis: sonographic findings in eight patients.

To determine the sonographic features of Yersinia terminal ileitis, we analyzed the sonograms of eight patients with acute terminal ileitis. Bacteriologic or serologic confirmation of Yersinia enterocolitica infection was available in six patients. In the other two, the clinical course and radiologic findings were compatible with the diagnosis. Radiographs and endoscopy showed edematous mucosa with small elevations in the terminal ileum in all the patients. Sonograms showed thickening of the wall of the ileum in all eight patients and enlarged mesenteric lymph nodes in six patients. Although the number of the patients is small, our experience suggests that sonography can be useful for the detection of acute terminal ileitis caused by Yersinia.

Adolescent↗
PubMed1979

Multiple adenocarcinomas and premalignant changes in "backwash" ileitis.

In a patient with long-staning ulcerative colitis and "backwash" ileitis, multiple carcinomas developed in the colon and ileum. In both locations premalignant mucosal changes of the basal cell proliferation type were seen adjacent to and remote from sites of carcinoma. Although the frequency of such premalignant and malignant changes in "backwash" ileitis is unknown, their concurrence in this case suggests that ulcerative colitis involving the terminal ileum increases the risk of small bowel carcinoma.

Adenocarcinoma↗
PubMed1991

Potential role of histamine monochloramine in a rabbit model of ileitis.

Histamine chloramines, derived from the chlorination of histamine by granulocyte-derived oxidants, are potential mediators of intestinal injury and dysfunction in states of atopy or inflammation. We assessed the ability of histamine monochloramine to increase epithelial permeability in rabbit distal small intestine and determined whether the conditions for histamine chloramine formation are favorable in a rabbit model of ileitis. Epithelial permeability, quantified by the blood-to-lumen clearance of 51Cr-labeled ethylenediaminetetraacetic acid, was enhanced by luminal perfusion with either histamine or histamine monochloramine (10 microM), although the latter was twice as effective (p less than 0.05). In a rabbit model of ileitis induced by a luminal solution of acetic acid (200 mM) and casein (10 mg/ml) there was a marked increase in epithelial permeability and in the release into the lumen of histamine, myeloperoxidase, 6-keto-prostaglandin F1 alpha and protein. These results suggest that the conditions are favorable for histamine chloramine formation and that histamine and histamine chloramine may impair the integrity of the epithelial barrier.

Acute Disease↗
PubMed1976

Acute yersinial ileitis: a distinct entity.

A case report of documented Yersinial acute ileitis is presented. A review of the literature reveals that progression to Crohn's disease is uncommon. Yersinosis can present as several symptom complexes. Mesenteric lymphadenitis and terminal ileitis, however, appear to be the most common. The diagnosis is usually made during laparotomy for possible appendicitis, because the symptom complex may be very similar. If the only finding at laparotomy is a thickened edematous ileum, postoperative titers for Yersinia should be taken. A greater awareness is necessary before the true incidence and epidemiology can be ascertained.

Acute Disease↗
PubMed1977

Acute terminal ileitis and Yersinia enterocolitica infection.

Diarrhea, moderate to high fever and pain in the RLQ associated with a tender mass or swelling of the terminal ileum arouse suspicion of acute terminal ileitis. Will diagnostic of the disease be laboratory data compatible with acute inflammatory disease and radiological findings of the terminal ileum, i.e., thickening of mucosal folds, round filling defects on the mucosa indicative of swelling of lymphoid tissue and fine irregularities of the margin without narrowing of the lumen. Yersinia infection was demonstrated in 7 of 10 patients whose stool and/or serum were examined. Yersinia enterocolitica was found to be an important causative agent of acute terminal ileitis. Its detection will be useful for differentiating the disease from acute stage of Crohn's disease.

Acute Disease↗
PubMed1976

Studies on Crohn's disease. 1. The relationship between Yersinia enterocolitica infection and terminal ileitis.

Patients with terminal ileitis or regional enterocolitis have been examined for signs of infection due to Yersinia enterocolitica serotype 3. The patients were grouped according to the length of preoperative history. Among 18 patients with preoperative symptoms of one week or less there were nine with positive signs of Yersinia enterocolitica infection. None of these patients developed the chronic form of Crohn's disease while two of the primarily Yersinia negative patients progressed to the chronic form. Among nine patients with preoperative symptoms of one week to three months there was one patient with positive signs of Yersinia enterocolitica infection. This patient has remained healthy whereas seven of the negative ones progressed to the chronic form of Crohn's disease. None of the patients with established Crohn's disease of the chronic form had signs of recent Yersinia infection. The findings indicate that patients with acute terminal ileitis and positive signs of Yersinia infection are not likely to progress to the chronic form of Crohn's disease. Bacteriologic and serologic investigation for Yersinia infection are therefore of prognostic value.

Acute Disease↗
PubMed1977

Long-term results in the treatment of regional ileitis with coherin.

Nineteen patients with severe symptoms of ileitis, not responsive to other forms of therapy, have been treated with coherin, a peptide isolated from bovine posterior pituitary glands. This study encompasses observations over a total of 50-patient years. tcoherin has proven efficacious by three criteria: As a result of coherin treatment those patients receiving steroids could either eliminate them or reduce the dosage to safe levels. A significant number of patients whose symptoms have been controlled by coherin have demonstrated their therapeutic dependence on coherin for relief of symptoms by multiple unsuccessful attempts to discontinue treatment over a long period of time. Diarrhea, in patients with ileitis symptoms, is effectively controlled by coherin therapy on a long-term basis.

Crohn Disease↗
PubMed1976

Regional ileitis (Crohn's disease). I. Kinetics of bile acid absorption in the perfused ileum.

Bile acid absorption was studied by steady state perfusion technique in the ileum of 11 patients with regional ileitis (Crohn's disease). By computerizing absorption kinetics the presence of an active transport of glycochenodeoxycholic acid (GCDC) was rendered probable by finding a saturable transport system and a competitive absorption between conjugated bile acids. At the time of investigation 5 patients had no diarrhoea, whereas 6 patients had diarrhoea as defined from the amount of faecal output. In the former group the faecal bile acid excretion was low, the ileal absorption of GCDC high, and judged from the xylose absorption the ileal absorption surface large compared to the latter group, in which the faecal bile acid excretion was high, the ileal absorption of GCDC low, and the ileal absorptive surface small. It is concluded that malabsorption of bile acids in the ileum may be of significant physiological importance in the pathogenesis of diarrhoea in patients with regional ileitis.

Adult↗
PubMed1976

Regional ileitis (Crohn's disease). II. Electrolyte and water movement in the ileum during perfusion with bile acids.

Electrolyte and water movement was studied by steady state perfusion technique in the ileum of 11 patients with regional ileitis (Crohn's disease). Six patients who at the time of investigation had diarrhoea showed a constant secretion of salts and fluid during perfusion with control perfusate. Per 24 hours, the ileal effluents to colon would exceed the normal amount by 1-2 litres. In the 5 patients without diarrhoea the absorption patterns were normal. Electrolytes and water moved in parallel. Dihydroxy bile acids enhanced secretion or decreased absorption respectively, in the two groups of patients. It is concluded that functional disturbances of salt and water absorption in the inflamed ileum may be of significant physiological importance in the pathogenesis of diarrhoea observed in patients with regional ileitis.

Adult↗
PubMedDate not supplied

Persistent ileitis after ileal salvage from a failed Kock pouch.

A case of persistent ileitis following the refashioning of a Kock ileal pouch into a Brooke ileostomy for severe pouchitis is reported. Preserving the terminal ileum by a salvage procedure may not be a safe alternative to pouch excision with the formation of a new end ileostomy in the surgical management of pouchitis refractory to medical treatment.

Adult↗
PubMed1976

Terminal ileitis, mesenteric lymphadenitis and appendicitis due to Yersinia pseudotuberculosis type VA: case report.

A case of terminal ileitis, mesenteric lymphadenitis and appendicitis is reported. Serological studies indicated infection with Yersinia pseudotuberculosis type VA. The patient's illness ran a chronic course necessitating resection of the terminal ileum. Histological examination of the appendix and a mesenteric lymph node in the acute stage revealed granulomas with central necrosis. This is the first human case in which the subtype VA has been identified.

Adult↗
PubMed1975

[Isolation of Yersinia enterocolitica in acute ileitis].

2246 stool specimens were specifically testet for Yersinia enterocolitica during 1973/74. In one case it was possible to isolate a strain of Yersinia enterocolitica (0-group I of Knapp/Serotype 3 of Winblad) from the feces of a patient suffering of acute ileitis. A high agglutinine-titer was serologically detected against a bacterial suspension of the isolated strain as well as of a reference strain (Serotype 3 of Winblad). The antibody-titer was 1 : 3200 by the first examination and dropped to 1 : 160 after two months. A reisolation attempt was unsuccessful.

Acute Disease↗
PubMed1977

[Eosinophil ileitis (author's transl)].

Eosinophilic ileitis is observed mainly in three coastal areas: Holland, Japan and Brittany. It presents in the form of a parietal inflammation, stenosing the intestinal lumen or a sessile tumour of limited volume. The symptoms are generally those of appendicitis but a past history of allergy and the discovery of eosinophilia greater than 10 p. cent may lead to the diagnosis of eosinophilic granuloma which only histology can confirm. Surgical treatment consists of segmental resection of the small intestine. The pathogenesis of the granuloma, which was for long attributed to the presence in the wall of the intestine of ascaris larvae, is at present debated. Are there non-parasitic eosinophilic granulomas? The case reported here is perhaps an example.

Adolescent↗
PubMed1975

Carcinoma of the small intestine associated with transmural ileitis (Crohn's disease).

A case of adenocarcinoma of the small bowel arising in pre-existing transmural ileitis (Crohn's disease) is reported and 28 previously reported cases are reviewed. Carcinoma associated with transmural enteritis occurs more often in the distal ileum, in younger patients, and in more males than expected from published data on carcinoma not associated with transmural enteritis. If the patient has had exclusion procedures, the carcinoma has been found to arise in the excluded bowel segment.

Adenocarcinoma↗