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At least 19 recordsLinked to original sources

Population stratification in Northern shrimp (Pandalus borealis) off Iceland evident from RADseq analysis.

The northern shrimp Pandalus borealis (ice. Stóri kampalampi) is a North Atlantic crustacean of significant commercial interest which has been harvested consistently in Icelandic waters since 1936. In Icelandic waters, the length at which this protandrous species transitions from male to female differs between the inshore and offshore populations, suggesting a biologically meaningful stratification which may or may not be plastic. Using reduced representative genomes assembled from RADseq data, sampled from 96 individuals collected at two time points (2018 and 2021), we compare the level of genetic structure across a gradient extending out of Skjálfandi bay, north Iceland. These data are compared to samples from a far offshore site, some 65 km out from the bay, as well as another inshore fjord in Arnarfjörður, in northwestern Iceland. Since 1999, no harvesting of inshore populations of P. borealis in Skjálfandi has been allowed due to stock decline, but harvesting of offshore stocks has continued. Uncertainty surrounding the extent of structure between the in- and offshore aggregations has remained. Here we report distinct genetic structure defining the inshore and offshore populations of northern shrimp, but find significant admixture between the two. Most importantly, we see that genetically inshore populations of northern shrimp extend far outside the harvest boundaries of inshore shrimp, and offshore individuals may exhibit punctuated migration into the inshore areas.

Animals

Multiple sclerosis and canine distemper in Iceland.

Iceland offers a favourable opportunity to examine the suggested relationship between canine distemper and multiple sclerosis. Distemper is not enzootic in Iceland and distemper immunisation is not practised. However, importations result in occasional epizootics, three of which have occurred since 1909. Careful enumeration of multiple sclerosis indicates that there were 129 cases during the period 1946--65. When these cases are subdivided into six regions, by place of birth, regional period-prevalence rates were highest in two regions partially involved by distemper only once in the past 70 years. Also, there was substantial prevalence in a third region, encompassing Reykjavik, where the dog population has been kept very low for over 50 years. The Icelandic experience indicates that multiple sclerosis can occur at high incidence in the virtual absence of canine distemper or in the presence of a very small dog population.

Animals

Skeletal maturation of the hand in Iceland.

The mean time at onset of the stages of skeletal maturation of the hand, PP2=, MP3=, S, MP3cap, DP3u, PP3u, and MP3u, in a cross-sectional sample of Icelandic school chidren in Reykjavík, a total of 1426 (690 boys and 736 girls), was assessed on radiographs of the hand and compared with results published from Denmark and Greenland. On the whole, the Icelandic children were most ahead, while S appeared at about the same time in all three nations. Otherwise, the mutual relationship between the skeletal stages was very similar. Girls reached all stages significantly sooner than boys, and this agrees with the findings in Denmark and in Greenland. The sex difference was most marked in the Icelandic material. The accidental error due to method in assessing the differences in skeletal maturation proved to be less than 5%, similar to that reported by others.

Adolescent

Prevalence of hypodontia and malformations of permanent teeth in Iceland.

This study was performed to elucidate the prevalence of hypodontia and congenital malformations of permanent teeth in Iceland. Computer analysis was done on the basis of results from examining 1,116 children (521 boys and 595 girls), or about 9.5% of all schoolchildren in Reykjavík in stages DS 3 (canines and premolars erupting) and DS 4 (canines and premolars fully erupted) of dental development at the time of the study. The age range was mainly from 8-16 years. The prevalence of congenitally missing teeth (second and third molars excluded) was 6.7% in boys and somewhat higher, 8.9%, in girls, 7.9% for both sexes combined. On the average, each child was missing 1.9 teeth. In the girls, the most commonly absent teeth were the mandibular second premolar (55%), the maxillary second premolar (19%), and the maxillary lateral incisors (18%). In the boys the figures were 51%, 18%, and 10%, respectively. Malformation of permanent teeth, mainly in the form of pegshaped maxillary laterals, was also less common in the boys, 1.3% against 3.0% in the girls, and 2.2% for both sexes combined. Among Icelandic children hypodontia and/or congenital malformation of permanent teeth were found in 9.1%.

Adolescent

Macroglobulinaemia in an Icelandic family.

Macroglobulinaemia in an Icelandic family is presented. A woman had Waldenström's macroglobulinaemia, and two of her brothers had monoclonal macroglobulinaemia of the benign form. One was asymptomatic, but the other had polyneuropathy and IgM deposits in peripheral nerves. A third brother of these siblings died of a lymphoreticular disease, which presented with a widespread neuropathy. A second sister had polyclonal increase in serum IgA and two other brothers of this sibship had IgM slightly elevated. A study of all descendants (45 in all and 19 spouses) revealed seven individuals with elevated IgM levels. No other immunoglobulin abnormalities were detected.

Aged

An epidemiologic study of dental space anomalies in Icelandic schoolchildren.

This study was performed mainly to determine the prevalence of space anomalies with regard to the various stages of dental development in Icelandic schoolchildren. The sample consisted of 1,641 randomly selected children (791 boys and 850 girls), making up 9.5% of the children attending all primary and secondary schools in Reykjavík during the school year 1972--73. In most of the frequencies of the different space anomalies boys showed a higher prevalence than girls. In both sexes there was often a significant difference from one stage of dental development to another. The results were compared with those reported for other ethnic groups.

Child

Anti-tissue antibodies and immunoglobulin levels in relation to HLA and other markers in Icelandic families.

Studies of 521 sera from the Icelandic cousin marriage project were made to assess the incidence of various anti-tissue antibodies and the levels of immunoglobulins, as these were considered to be useful markers of the humoral immune response. Comparisons were made between these parameters and the HLA-A and B antigens, the blood groups, the immunoglobulin allotypes (Gm, Km and Am), the properdin factor (Bf), and other markers. These investigations offered another approach to the study of the sites of action of immune response genes in man. Because the immune response may be expected to differ for each individual and depend at least in part, on the degree of exposure to different antigens, no absolute correlation was expected. There was, however, a marked association between certain IgG anti-tissue antibodies and HLA antigens. This was most marked for HLA-A10, B18 and b27, but not for HLA-A1 or B8. The comparison of immunoglobulin levels with HLA antigens, was less striking, although HLA-A2 appeared to be associated with low levels of IgE. There were also some associations between immunoglobulin levels and ABO blood groups.

Aged

A rare electrophoretic enzyme variant of serum alkaline phosphatase in a group of Icelanders.

An electrophoretic isoenzyme variant of serum alkaline phosphatase was found in 10 out of 343 subjects belonging to an Icelandic population in Husavik and the Husavik region. 9 of the variant-positive subjects were women. The enzyme variant differs from normal isoenzymes in electrophoretic mobility, substrate specificity, and response to inhibitors. It could be demonstrated that nine of the subjects with the enzyme variant were related with each other.

Adult

Survey of serum lipid levels in Icelandic men aged 34-61 years. An epidemiological and statistical evaluation.

This report presents the results of serum beta-lipoprotein, total cholesterol and triglycerides determinations in a male population surveyed 1967--'68. This was the first stage (stage I) in a prospective health survey conducted by the Icelandic Health Association. The area of study was the city of Reykjavík with adjacent suburbs and communes. The population invited was 1/3 of each of 16 year-groups of males in the age-interval 34-61 years. The population was selected from the National Roster according to birthdays i.e. the 1st, 4th, 7th,.. of each month, the total number being 2.955. The response was 75.1%. B-lipoproteins were determined with the Hyland Beta-L Test, total cholesterol and triglycerides on Technicon AutoAnalyzer (i) according to Technicon Methodology N-24a, and a modification of the method of Kessler and Lederer respectively. Control sera were run in connection with cholesterol- and triglycerides determinations. Serum cholesterol levels were similar to the highest reported from other countries contrary to the triglycerides levels which are in the low range. The mean values and lower centiles are practically independent of age whereas the higher centiles are markedly age-dependent. A seasonal variation for the cholesterol weekly mean values was found. These values were highest in winter and lowest in summer, the difference estimated to be 30-40 mg%. No seasonal variation of triglycerides was found. Centile-flowdiagrams for these blood lipids are presented and the use of similar flowdiagrams is suggested as an aid to bridge a gap between the interpretation of cross-sectional and longitudinal studies.

Adult

Tumours in Iceland. I. Malignant tumours of skin--a histological classification.

Four hundred and eighty-five primary malignant skin tumours submitted for histological diagnosis in Iceland during the period 1955--1974 were typed according to the WHO histological classification. The incidence of these tumours, age-adjusted to the "World" population, was 12.6/100.000 in males and 11.0/100.000 in females. These are very low figures for a white population. The distribution by type among males was: basal cell carcinoma 66.8%, squamous cell carcinoma 22%, malignant melanoma 7.2% and others 4%. Among females: basal cell carcinoma 66.9%, malignant melanoma 20.8%, squamous cell carcinoma 10.2% and others 2.1%. The exposed areas of the body were affected much more frequently than other areas. The results support the theory that intensity of solar radiation is of major aetiological significance.

Adenocarcinoma

Frequency of IgA deficiency in blood donors and Rh negative women in Iceland.

Sera from 6,842 individuals were tested for IgA deficiency, using double and radial immunodiffusion. Sera containing less than 1 mg/100 ml of IgA were classified as deficient. The frequency of selective IgA deficiency among 4,799 blood donors investigated was 1:533, but 1:340 among 1,017 Rh negative women screened and 1:485 for both groups combined. One of the nine IgA deficient blood donors detected belonged to a 1st cousin marriage family previously investigated, in which the mother also was deficient in IgA. One IgA deficient recipient was found among 704 hospital patients screened for this abnormality.

Adolescent

Multiple sclerosis and common viral infections in Iceland.

Sero-epidemiological studies on a few common virus infections, including measles, rubella, mumps and varicella-zoster, were carried out on patients with multiple sclerosis (MS) and controls matched for age, sex, and residences since birth. The frequency of antibodies against measles was significantly higher in the MS patients. Where measles preceded the onset of MS, the time interval varied from 3 to 32 years. In two cases, known MS patients contracted measles 9 and 3 years after their onset of MS. Furthermore, three MS patients were vaccinated against measles as adults. Two of these took part in a WHO measles vaccine trial in 1962, 18 and 6 years after the onset of MS. Both of them were seronegative prior to vaccination.

Adolescent

Drug prescription in Iceland.

Two ad hoc surveys on drugs prescribed in Reykjavik during November 1972 and November 1974 were made. After the first survey a publicity campaign was launched and doctors were encouraged to change their prescribing habits; only minor changes in docotors' prescribing habits were noticed, although it is realised that this type of programme will require a longer period to prove its effectiveness. The surveys showed that benzodiazepines are more widely prescribed than chlorodiazepoxide. Doctors have been warned of the probable addictive effect of benzodiazepines (Grimsson et al., 1974). Drug addicts who used to go from one surgery to another have now been identified and they can only receive drugs on prescription from their own family doctor or his deputy.

Anti-Anxiety Agents

Mortality among men alcoholics in Iceland, 1951--74.

In close to 3000 alcoholics followed up from 4 to 24 years after first contact with a treatment facility, the death rate was more than double the expected rate; the rates of death due to accidents and suicides were 4 times the expected rates.

Accidents