Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Hemic System”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1992

Assessment of the hematopoietic system in ruminants.

The hemic system is examined to evaluate clinical signs referable to the hemic system, establish a data base, or monitor the course of disease processes. Clinical signs of hemic disorders include pale mucous membranes, icterus, hemorrhage, hemoglobinuria, and tachycardia. Compared to other species, ruminants have small red blood cells, respond to anemia by releasing stippled red blood cells, commonly become neutropenic during acute bacterial sepsis, and fail to develop marked neutrophilia or left shift in response to inflammation.

Animals↗
PubMed1995

Schedule for rating disabilities; hemic and lymphatic systems--VA. Final rule.

This document amends the Department of Veterans Affairs' (VA) Schedule for Rating Disabilities of the Hemic and Lymphatic Systems. The effect of this action is to update the hemic and lymphatic portion of the rating schedule to ensure that it uses current medical terminology and unambiguous criteria, and that it reflects medical advances that have occurred since the last review.

Diagnosis-Related Groups↗
PubMed1981

[Instrumentation and methods in policardiography (author's transl)].

Although policardiography has been in use for more than a century, only recently attention has been focused on instrumental and methodological problems of the technique. Among these, frequency response and time constant of the equipment are in first place. Time constant must be long enough to allow an accurate recording of the low and ultra-low frequency vibrations which are generated in the cardio-aorto-hemic system, in particular of those constituting the carotid pulse and the apexcardiogram. The authors stress the influence that incidental air leaks in the recording assembly, or type and size of the pickup device, have on the value of the time constant. Kinetocardiography seems preferable to apexcardiography in order to reproduce with higher fidelity absolute movements of the anterior thoracic wall in every single point.

Carotid Arteries↗
PubMed1996

A review of clinical experience with the novel immunosuppressive drug mycophenolate mofetil in renal transplantation.

This review gives a summary about the current knowledge on the novel immunosuppressive drug mycophenolate mofetil (RS61443) in renal transplantation. The results of the preclinical pilot trials and of the so far published pivotal study for the prevention of rejection are described. Mycophenolate mofetil (MMF), the 2-4-morpholino ethyl ester of mycophenolic acid, is an inhibitor of the Inosine Monophosphate Dehydrogenase, an enzyme in the de novo synthesis of purines. MMF showed no clinical significant interactions with a variety of medications used in renal transplantation. Following oral administration it is rapidly absorbed. Pilot studied suggested a significant reduction in the incidence of rejection at doses of 2 g/day. 491 patients were enrolled in a randomized, double blind, multicentre, placebo-controlled study of the addition of mycophenolate mofetil to cyclosporine and oral corticosteroids for the prevention of acute renal allograft rejection. After six month the rates for biopsy proven rejection were the following: placebo 46.4%, MMF 2 g 17.0% and MMF 3 g 13.8%. The adverse event profile resembles that of triple therapy with azathioprine. Most adverse events concerned the gastrointestinal tract, the hemic system and opportunistic infections. MMF offers an improved immunosuppressive therapy following renal transplantation.

Clinical Trials as Topic↗
PubMed1990

Hormonal influence on calcitonin gene-related peptide in man: effects of sex difference and contraceptive pills.

Calcitonin gene-related peptide (CGRP) is one of the peptides encoded for by the calcitonin gene. It has been demonstrated in man to be located in the thyroid and in perivascular nerves and to possess potent vasodilatory properties. In the present study we found plasma levels of calcitonin gene-related peptide-like immunoreactivity (CGRP-LI) to be significantly higher in females than in males and that women on contraceptive pills had significantly higher CGRP-LI levels than women not taking contraceptives. These data are in accordance with one earlier report on an increased CGRP level during pregnancy and suggest a positive influence of the female sex hormones on the plasma CGRP level in man, which should be considered in the establishment of a reference range for this analysis.

Adult↗
PubMed1989

Effect of Norplant contraceptive use on hemoglobin, packed cell volume and menstrual bleeding patterns.

A study was conducted to evaluate the effect of NORPLANT use on hemoglobin levels (HB), packed cell volume (PCV) and menstrual bleeding patterns. NORPLANT insertions were performed on 50 healthy volunteers in Ilorin, Nigeria, between January-March 1986. Whole blood samples were collected at admission, 6-month and 12-month follow-up visits, and each acceptor was asked to keep a daily bleeding calendar. Mean age of the acceptors was 32.8 years with a mean parity of 5.3 live births. Almost 50% of the acceptors indicated that they did not want any more children. After 12 month's follow-up, there were a total of three discontinuations, two for excessive menstrual bleeding and one due to husband's objection. Mean HB and PCV values remained relatively unchanged from admission to 12 months. Nearly 50% of the women experienced at least one episode of 8 or more days of continuous bleeding during the first six months of use, and about 20% reported amenorrhea of 90 or more days. Despite the incidence of menstrual bleeding irregularities, acceptability of the NORPLANT method was high as indicated by a 1-year continuation rate of 93.7 per 100 users. Clinically more important was the finding that despite a high proportion of women reporting menstrual pattern changes, HB and PCV levels remained unchanged.

Adult↗
PubMed1984

Melatonin in relation to body measures, sex, age, season and the use of drugs in patients with major affective disorders and healthy subjects.

Serum melatonin levels over a 24 hr period were studied in 30 acutely ill patients with major depressive episode, 24 patients with a history of unipolar or bipolar major affective disorder in remission and 33 healthy subjects. A significant negative correlation (-0.45) between body height and maximum nocturnal serum melatonin level was found. Maximum serum melatonin levels during the night were lower in both patient groups than in the healthy controls. No difference was found between maximum nocturnal serum melatonin levels in 26 patients investigated when ill and again in remission. We thus propose low nocturnal melatonin to be a trait-dependent marker for major depressive disorder. A difference in the morning but not night melatonin levels was found between samples taken during the dark, winter season versus samples taken during the bright, spring-summer season. Melatonin levels were not lower in females than in males, when melatonin levels were adjusted for body height. Similar results were found when the nocturnal areas under the curve for melatonin were analyzed.

Adult↗
PubMed1991

Depressed erythropoietic activity of Nigerian pregnant women.

Reticulocytes production index was determined in 63 pregnant women and in 96 patients. The results show that 86% of the pregnant women, who were registering their pregnancy for the first time, were anaemic. There was significant reticulocytopenia in all the anaemic pregnant women and in the patients. Erythropoiesis was found to be depressed in all subjects patients by two to seven times those expected in normal responsive bone marrows. There was no correlation of the bone marrow impairment with parity of the pregnancy. The bone marrow impairment was more pronounced during the 16th week of gestation and less so in older pregnancies. Malnutrition and infection (especially malaria) are suggested as the aetiological factors of the bone marrow depression of erythropoiesis.

Adolescent↗
PubMed1981

Acute experimental canine ehrlichiosis. I. Sequential reaction of the hemic and lymphoreticular systems.

Dogs with acute Ehrlichia canis infection showed the established clinical features of acute ehrlichiosis and had thrombocytopenia, anemia, increased serum glutamic pyruvic transaminase activity, and decreased total serum protein and albumin concentrations during the first weeks after infection, and increasing gamma globulin concentrations after the third week. Gross lesions in hemic and lymphoreticular tissues were transient lymphadenomegaly, splenomegaly, and increased red long-bone marrow. Lymphoreticular hyperplasia in the paracortical area of lymph nodes and in the splenic red pulp occurred during the second week of infection. Later, small lymphocytes were replaced by medium-sized lymphocytes and plasma cells. Activity of germinal centers increased initially, as shown by numerous mitotic figures and macrophages, but diminished later, and the follicles blended with interfollicular and paracortical tissue because of a decrease in small lymphocytes in the mantle layer. We saw splenic hemorrhages near the perifollicular sinus, and vasculitis, most often phlebitis, in the kidney between weeks 2 and 4. Multifocal reticuloendothelial hyperplasia occurred in the liver during the early stage and injured adjacent hepatocytes by compression. Lesions typical of ehrlichiosis in these dogs were interstitial pneumonia, subendothelial aggregates of mononuclear cells in pulmonary blood vessels, renal periglomerular and perivenular plasmacytosis, hemopoietic hyperplasia, and perivascular cuffs of lymphocytes and plasma cells in many organs.

Acute Disease↗