The Novel HLA-B*40:01:92 Allele Identified in Patient and His Related Donor.
The novel HLA-B*40:01:92 allele differs from B*40:01:01:01 by a change of C → A in exon 5.
Humans↗
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Identification of the Novel HLA-B*40:160:01:02 Allele.
The novel HLA-B*40:160:01:02 allele differs from HLA-B*40:160:01:01 at position 691 (G>T) in intron 2.
Humans↗
Two New Alleles, HLA-B*40:06:01:20 and HLA-DRB1*09:61N, Detected in a Spanish Bone Marrow Donor.
Genomic sequence of HLA-B*40:06:01:20 and HLA-DRB1*09:61N alleles detected in a Spanish individual.
Humans↗
The Novel HLA-B*40:542 Allele Was Identified by Next-Generation Sequencing.
HLA-B*40:542 differs from the HLA-B*40:23 allele by two nucleotide substitutions in exon 3.
Humans↗
Characterisation of the Novel HLA-B*40:01:02:68Q Allele by Sequencing-Based Typing.
HLA-B*40:01:02:68Q differs from HLA-B*40:01:02:01 by one nucleotide substitution in intron 2 at the splice site with exon 3.
Humans↗
On the heterogeneity of B40.
Evidence is presented for the heterogeneity of HLA-B40. At least two sub-groups can be recognized: Bw40.1 which is Cw3 associated and Bw40.2 which is Cw2 associated in Caucasians, but not in other populations. The recognition of Bw41 (Sabell), Bw47 (407*), and Bw48 (KSO) with both local Bw40 antisera and sera from the 7th Histocompatibility Workshop is discussed.
Absorption↗
HLA and Japanese MS.
Determination of HLA-A, -B and -C types in 43 Japanese patients with multiple sclerosis (MS) and of DR type in 25 MS patients was carried out using antisera from the 7th International Histocompatibility Workshop. The results were compared with 46 controls typed simultaneously. Twenty-three patients were also tested for HLA-Dw2. The conclusions were: 1) There were no significantly higher occurrences of HLA-A3, B7, Dw2 or DRw2 in Japanese MS. 2) Japanese MS might nevertheless be associated with the human major histocompatibility complex, because HLA-B40 was significantly less frequent in MS and two anti HLA-DRw sera, 7w008 and 034, reacted positively more often against lymphocytes from MS patients.
Epitopes↗