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The prevalence of the metabolic syndrome in Greece: the MetS-Greece Multicentre Study.

BACKGROUND: The Third Report (ATP III) of the National Cholesterol Education Program Expert Panel (NCEP) highlighted the importance of identifying and treating patients with the metabolic syndrome (MetS) to prevent cardiovascular disease (CVD) and progression to diabetes mellitus. Limited information is available about the prevalence of MetS, as defined by the NCEP ATP III, in Europe, especially in Greece. OBJECTIVE: To estimate the prevalence of the MetS in Greece, The MetS-Greece Study. DESIGN AND PARTICIPANTS: A cross-sectional analysis of a representative sample of Greek adults (4153 participants older than 18 years). One group consisting of military personnel (n = 300) and another one from a Greek Muslim Community (n = 300) were used for comparison. In all, 4753 subjects were included in the final analysis. RESULTS: All subjects from the general population were Caucasian men (49%) and women (51%), living in urban (n = 2243, 54%), semi-urban (n = 1038, 25%) and rural (n = 872, 21%) areas. The age-standardized prevalence of the MetS was 23.6%[95% confidence interval (CI): 22.4-25.1%]. This was similar in men (24.2%, 95% CI: 22.3-25.2%) and women (22.8%, 95% CI: 21.4-25.0%) (p = 0.3). The prevalence increased with age in both sexes, 4.8% among participants aged 19-29 years and 43% for participants over 70 years old (p for trend < 0.0001). There was a 14.7-fold increase in odds ratio for having MetS in the age group > 70 years old compared with that of 19-29 years old (p < 0.0001) Most of those with MetS had three components of the syndrome (61%), 29% had four and 10% had all five components. Abdominal obesity (82%) and arterial hypertension (78%) were the most common abnormalities in both sexes. The Greek Muslim Community, on a high-saturated fat diet, had the highest prevalence of the MetS (35.2%, 95% CI: 30.4-40.3%), and the military group, with a high physical activity level and a diet 'close' to Mediterranean, had the lowest (9.4%, 95% CI: 6.2-13.1%). According to the 2001 Census, about 2.3 million Greeks may have the MetS. CONCLUSIONS: These results show that the MetS is highly prevalent in the Greek adult population. This may have major implications for the incidence of CVD. Promoting healthy diets, low caloric intake and physical activity must be urgently undertaken.

Adolescent↗

Diphtheria immunity of Albanian and other eastern European immigrants in Greece compared with the local population--the risk of reemergence in Greece.

A large number of immigrants have come to Greece from diphtheria-endemic countries during the past 8 years. Information on the immune status against diphtheria among immigrants from Albania and the New Independent States (NIS) of the former USSR, as well as the Greek population, is essential in planning public health control measures. The main objective of the study was to determine the risk of the spread of diphtheria if new cases arrived in the country. Diphtheria antitoxin (DAT) in sera from 185 healthy individuals from northern Greece and 227 immigrants from Albania and the NIS was titrated using a quantitative ELISA test. The participants were adults aged 22 to 46 years. Titers were considered as protective when DAT levels were higher or equal to 0.1 IU/ml. Albanian immigrants exhibited the highest rates of protective titers (99 of 167, 59.3%), while lower immunity rates were detected among immigrants from the NIS (20 of 60, 33.3%) (1.5 < OR = 2.9 < 5.4, p = 0.0007) as well as among Greek participants (47 of 185, 25.4%) (2.8 < OR = 4.4 < 7.0, p = 0.00001). Immunity rates did not differ between Greek and NIS participants. DAT levels of persons with protective titers differed between the three population groups (analysis of variance, p = 0.0005), with the highest mean DAT values detected among NIS immigrants (0.613 IU/ml). Lower values were found among protected Albanians (0.482 IU/ml) and Greeks (0.314 IU/ml). There was no significant age- and sex-related difference in immunity rates and DAT levels among the groups. The low immunity rates among Greek adults might suggest that they have had no natural contact with toxigenic strains of corynebacteria. A booster dose of diphtheria toxoid for local adults is recommended, to reduce their risk of acquiring toxigenic strains from individuals who may carry the bacteria without exhibiting clinical disease.

Adult↗

Incidence and characteristics of childhood Hodgkin's lymphoma in Greece: a nationwide study (Greece).

OBJECTIVES: To estimate the incidence and epidemiological profile of childhood (0-14 years) Hodgkin's lymphoma in Greece derived by the network of childhood Hematology-Oncology departments on the basis of all 95 newly diagnosed cases during a seven-year period. METHODS: Seventy-one of these cases were individually age and gender matched to an equal number of controls. RESULTS: The incidence of childhood Hodgkin Lymphoma reached a relatively high figure of 7.8 per million children-years, with an age distribution (2.2 for children 0-4; 6.3 for those 5-9 and 13.9 for those 10-14-years-old) and male to female ratio (1.7:1) similar to that reported from other cancer registries. Childhood Hodgkin's lymphoma was more common among children living in less crowded quarters (odds ratio (OR): 6.5 and 95% confidence intervals (95% CI): 1.4-30.7), among those who have changed residence 60 to 18 months before the onset of the index disease (OR: 4.4, and 95% CI = 1.4-14.0), among those whose families owned a cat (OR: 5.5, 95% CI = 1.2-25.6) but not among those whose families owned a dog and marginally more common, among those with a history of infectious mononucleosis (OR: 5.0, 95% CI = 0.6-42.8). CONCLUSIONS: Our results point to infectious agent(s) as playing an etiological role but do not allow discrimination among the delayed establishment of the herd immunity hypothesis, the population mixing hypothesis or that invoking transmission of the agent(s) from the non-human reservoir.

Adolescent↗

Nested clade and phylogeographic analyses of the chub, Leuciscus cephalus (Teleostei, cyprinidae), in Greece: implications for Balkan Peninsula biogeography.

Phylogenetic relationships among Greek populations of the chub, Leuciscus cephalus, were investigated using 600 bp of the cytochrome b gene. The aim of this study was to test the assumption that the main difference in ichthyological composition between both sides of the Balkan Peninsula is directly linked to differences in the dispersion mechanisms used by fish in order to extend their distribution range. Phylogenetic and nested clade analyses clearly showed that populations in Greece are significantly differentiated. Greek populations were found to descend from three lineages in three geographical provinces: Western, Central, and Eastern Greece. The chub reached Western Greece at the beginning of the Pleistocene and Eastern Greece during the mid-Pleistocene. Chub dispersion occurred mainly by river confluence due to sea level lowering and river capture in Western Greece and sea dispersal with low-salinity conditions within the Aegean Sea in Eastern Greece. However, in Central Greece, the original mtDNA lineage has presumably been lost owing to a genetic introgression following a second invasion from the Danube during the final stage of the last glaciation. This study provides new elements for a better understanding of the composition of the contemporary ichthyofauna in Greece and highlights possible evolutionary mechanisms responsible for the high endemism rate in the Western Greek biogeographic province.

Animals↗

Smoking policy and prevalence in Greece: an overview.

BACKGROUND: Smoking is one of the largest public heath problems and a cause of major concern not only among European members such as Greece but also worldwide. Greece over the past years has been suffering from a smoking epidemic with dramatic consequences on the economy and the cost of health services. Therefore, the purpose of this study is to describe the extent of tobacco usage, the methods used to control tobacco consumption, and the main reasons of anti-tobacco legislation failure over the past decades in Greece. METHODS: Data were collected from the international PubMed database and from the Greek database, Iatrotek, during January 2006 and the tobacco legislation was discussed with other counterparts in Greece and was rechecked with the Greek ministry of Health and Social Welfare. RESULTS: Currently Greece has the highest smoking prevalence not only among members of the European Union but also among all members of the OECD. Recent epidemiological studies estimate that 40% of the adult population are daily smokers, with one in two adolescents in certain areas also current smokers. Although anti-smoking policies do exist, and have been enforced over the years, many factors have contributed to their failure with a pro-tobacco culture and an increasing number of adolescent smokers exacerbating the problem. CONCLUSIONS: It is obvious that the strict enforcement of a nationwide anti-tobacco policy must be a priority on the national health agenda, if we are to ever effectively combat the high prevalence of smoking in Greece.

Greece↗

Self-reported prevalence of obesity among 20,329 adults from large territories of Greece, Serbia and Turkey.

The aim of this study was to investigate the prevalence of overweight, obesity and body mass index (BMI) distribution in people living in large territories of Greece, Serbia and Turkey. A cross-sectional multi-national epidemiological survey was designed on the basis of self-reported information on height and weight using the formula kg/m2. Overall, 20,329 individuals, aged 20-68 yrs, 8,973 males and 11,356 females, participated in the study. Of these, 4,032 were selected from northern Greece, 10,069 from southwest Turkey and 6,228 from central Serbia. More specifically, participants from northern Greece were recruited from central Macedonia, from Southwest Turkey from the Kayseri region and from central Serbia from the greater Belgrade area. Our results showed that 12.4% of the population studied was obese and 31.3% overweight. The corresponding figures for participants from Greece were 19.9% and 35.4%, from Turkey 12.0% and 30.9% and from Serbia 8.2% and 29.4%, respectively. Overall, male participants had a higher mean BMI than females. However, Greek females were more obese in comparison with males. The opposite was true of the other two countries. Finally, in both males and females mean BMI tended to increase with age up to 50-59 years, and declined slightly thereafter. In conclusion, the overall prevalence of obesity and overweight in the Balkan peninsula does not differ from that reported in other European countries. However, BMI values between different countries of the Balkan peninsula are fairly variable, Greece leading in the prevalence of obesity with Serbia having the lowest prevalence of obesity. The data from this survey underline the need for health intervention aimed at preventing obesity, especially in Greece.

Journal Article↗

A heuristic expert system for forest fire guidance in Greece.

Forests and forestlands are common inheritance for all Greeks and a piece of the national wealth that must be handed over to the next generations in the best possible condition. After 1974, Greece faces a severe forest fire problem and forest fire forecasting is the process that will enable the Greek ministry of Agriculture to reduce the destruction. This paper describes the basic design principles of an Expert System that performs forest fire forecasting (for the following fire season) and classification of the prefectures of Greece into forest fire risk zones. The Expert system handles uncertainty and uses heuristics in order to produce scenarios based on the presence or absence of various qualitative factors. The initial research focused on the construction of a mathematical model which attempted to describe the annual number of forest fires and burnt area in Greece based on historical data. However this has proven to be impossible using regression analysis and time series. A closer analysis of the fire data revealed that two qualitative factors dramatically affect the number of forest fires and the hectares of burnt areas annually. The first is political stability and national elections and the other is drought cycles. Heuristics were constructed that use political stability and drought cycles, to provide forest fire guidance. Fuzzy logic was applied to produce a fuzzy expected interval for each prefecture of Greece. A fuzzy expected interval is a narrow interval of values that best describes the situation in the country or a part of the country for a certain time period. A successful classification of the prefectures of Greece in forest fire risk zones was done by the system, by comparing the fuzzy expected intervals to each other. The system was tested for the years 1994 and 1995. The testing has clearly shown that the system can predict accurately, the number of forest fires for each prefecture for the following year. The average accuracy was as high as 85.25% for 1995 and 80.89% for 1994. This makes the Expert System a very important tool for forest fire prevention planning.

Conservation of Natural Resources↗

A comparative study of psychopathology in Greek adolescents in Germany and in Greece in 1980 and 1998--18 years apart.

OBJECTIVE: In the 1980s, we assessed Greek adolescents living in Germany and Greek adolescents living in Greece. Data from this earlier study supported the hypothesis of selective migration with higher psychopathology self-rating scores in Greek adolescents in Greece as compared to Greek adolescents in Germany. The current study uses the same design and instruments so that the comparison of the mental health of populations in the same areas, almost two decades apart, becomes possible. METHODS: In 1980, a total of 2631 Greek adolescents were assessed in Munich, Germany or Veria, Greece. In 1998, 2920 Greek adolescents were assessed in Munich, Germany and Veria, Greece. The General Health Questionnaire (GHQ-28) was used to assess mental health status at both times. RESULTS: 1) GHQ-28 scores showed a significant increase from 1980 to 1998 in both locations. 2) While in 1980, Greeks in Veria, Greece had higher psychopathology scores than Greek adolescents in Munich, Germany, this (with the exception of depression) was no longer true for 1998. 3) At both times and both locations adolescent girls scored higher in the GHQ-28 than adolescent boys. CONCLUSIONS: While the 1980 data supported the selective migration hypothesis, this was no longer true for the 1998 data. The increase in psychopathology in both locations is alarming and deserves further exploration.

Adolescent↗

Hepatitis B immunization programme: lessons learnt in Greece.

Historically, Greece has had the highest burden of hepatitis B virus (HBV) infection in the European Union (EU). Heterosexual contact is the primary means of HBV transmission in Greece, accounting for approximately 30% of acute cases in adult males and 50% of acute cases in women of reproductive age [Kattamis C, Papevangelou G. Workshop Group: Greece. Vaccine 1995;13:S97-S98.]. In 1982, Greece implemented a hepatitis B prevention programme aimed at high-risk groups; unfortunately, this approach had little impact on disease incidence or prevalence. At the recommendation of the WHO and the World Health Assembly and after sustained lobbying by several scientific and medical associations in Greece, the Greek government decided to implement a national prevention programme for hepatitis B. The programme, in effect from early 1998, includes the screening of pregnant women, universal infant and adolescent immunization and immunization of high-risk groups.

Adolescent↗

Migration and HIV epidemic in Greece.

BACKGROUND: Over the last decade, Greece has experienced a massive influx of migrants from countries in South Eastern/Central Europe, the Middle East, Asia and Africa. This study aimed to estimate the percentage and the specific characteristics of HIV-positive migrants reported in Greece, and to describe the secular trend of migrants' proportion among HIV-infected individuals. METHODS: Secondary analysis of data reported to the Hellenic Centre for Infectious Diseases Control (HCIDC) during the years 1989-2003. RESULTS: From 1989 to 2003, 6292 HIV-positive cases were reported to HCIDC. Data show that 749 people (439 males, 303 females) originated from countries other than Greece. Most HIV-positive migrants come from Sub-Saharan Africa (32.44%) and nearly 20% from Central and Eastern Europe. In the Greek population, men who have sex with men (MSM) constitute 50.47% of cases, while 16.15% are heterosexuals. The epidemic profile follows a different pattern among migrants (P<0.05). Heterosexual transmission accounts for 41.52% of HIV-positive reported migrants, while 19.09% are MSM. An 11% increase for each subsequent year in the rate of HIV-positive migrants reported in Greece has been estimated using a Poisson regression model fitted to the data (IR 1.11; 95% confidence interval 1.08-1.13). CONCLUSIONS: The results suggest an increasing trend of HIV-seropositive migrants in Greece during recent years. Group-based interventions, better access to health care and a comprehensive public approach should be applied to migrants.

Adult↗

Increase in congenital rubella occurrence after immunisation in Greece: retrospective survey and systematic review.

OBJECTIVE: To describe the events leading to the epidemic of congenital rubella syndrome in Greece in 1993 after a major rubella epidemic. DESIGN: Retrospective survey and systematic review. SETTING: Greece (population 10 million), 1950-95. SUBJECTS: Children, adolescents, and women of childbearing age. RESULTS: Around 1975 in Greece the measles, mumps, and rubella vaccine started being given to boys and girls aged 1 year without policies to attain high vaccination coverage and to protect adolescents and young women. During the 1980s, vaccination coverage for rubella remained consistently below 50%, and the proportion of pregnant women susceptible to rubella gradually increased. In 1993 the incidence of rubella in young adults was higher than in any previous epidemic year. The epidemic of congenital rubella that followed, with 25 serologically confirmed cases (24.6 per 100 000 live births), was probably the largest such epidemic in Greece after 1950. CONCLUSIONS: With low vaccination coverage, the immunisation of boys and girls aged 1 year against rubella carries the theoretical risk of increasing the occurrence of congenital rubella. This phenomenon, which has not been previously reported, occurred in Greece.

Adolescent↗

Surgery in Greece.

The expenditure on health care reached 7.8% of the gross domestic product in Greece in 1991. Almost 9000 specialized surgeons in 11 recognized specialties provide services to more than 10 million people living in Greece and 2 million visitors annually. Medical studies comprise a 6-year course of 5000 to 5500 teaching hours in 7 medical schools and are free. Organizational reform of the health care system in vital and long overdue to move the system into the 21st century. The quality of surgical services provided is high by international standards; cardiac surgery, organ transplantation, surgical oncology, and anesthesiology are some areas of excellence. In addition, Greece has a good record in medical technology and instrumentation. Research activities cover a range of subjects, and the number of clinical medicine articles from Greece that appear in peer-reviewed journals compares favorably with other larger countries. Reforms in the postgraduate training system and ongoing education are necessary.

Delivery of Health Care↗