Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Glycosuria”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources
PubMed1978

The spontaneously diabetic Wistar rat (the "BB" rat): the significance of transient glycosuria.

A longitudinal study of thirteen rats with transient and intermittent episodes of glycosuria was undertaken, to further characterize the "BB" diabetic syndrome. "Chemical diabetes" (normal fasting glycemia, abnormal GTT) was observed in five rats, accompanied by the same dramatic insulitis previously reported in this syndrome, in two of the three pancreases examined. Progression from "chemical" to overt diabetes occurred in one of these rats. Two other patterns of presentation were observed. Periods of complete remission occurred in four rats with diabetes considered sufficiently severe to warrant previous treatment with insulin. Four additional rats with previous glycosuria (untreated) showed no abnormalities on followup. It is not known whether hyperglycemia accompanied the glycosuria in these rats, and renal glycosuria has not been excluded. Thus, the "BB" diabetic syndrome exists in not only the overt and "chemical" forms, but may also present with transient glycosuria, followed by a variety of subsequent progressions.

Animals↗
PubMedDate not supplied

[Importance of glycosuria in pregnant women as a risk factor in relation to diabetes mellitus].

The diabetic type of glucose tolerance tests was revealed in 16% of the women with glycosuria during pregnancy and in 8% of the women of control group without any other risk factors in respect to diabetes mellitus. The results of remote follow up over the women of the both groups are presented. Glycosuria during pregnancy should not be considered prognostically unfavourable in case of normal glucose tolerance test results; pathogenesis of such glycosuria during pregnancy was not associated with insulin insufficiency. Glycosuria during pregnancy served as an indication of the glucose tolerance test for the purpose of timely detection of latent diabetes.

Adult↗
PubMed1976

Micropuncture studies of glucose transport in the dog: mechanism of renal glycosuria.

Clearance and micropuncture studies were performed in 23 dogs without glucose loading to examine the tubule mechanism of renal glycosuria. Studies were carried out in three groups of animals before and after 10% extracellular volume expansion, and administration of maleic acid in low dose at 150 mumol/kg and in high dose at 300 mumol/kg. Specific hexokinase methods were used for the determination of glucose in tubule fluid and urine. Under control conditios, glucose reabsorption occurred predominantly in the proximal tubule. In all three groups, proximal tubule reabsorption of both sodium and glucose was inhibited in the second phase, showing a good correlation between the two. In contrast, fractional urinary glucose excretion remained unchanged after volume expansion and low-dose maleic acid, indicating reabsorption of virtually all the increased glucose load at a further "distal" site. On the other hand, significant glycosuria developed after high-dose maleic acid that was a result of reduced glucose reabsorption in the distal nephron, in addition to the proximal effect. It was concluded that distal glucose transport plays a significant role in regulating urinary glucose excretion and maintains renal thershold for glucose,

Aminohippuric Acids↗
PubMed1978

[Renal glycosuria with loss of phosphate (author's transl)].

Three of six members of one family have a renal glycosuria of variable degree. In addition to this they have a mild loss of phosphate under normal conditions. In one patient the phosphate-loss becomes very high after a loading dose. After describing the different data the mechanism of renal glucose transport and its relationship to phosphate transport as well as the genetic of renal glucosuria are discussed. The combination of renal glycosuria and renal loss of phosphate is very rare. The difference in regard to gluco-phosphaturia is mentioned.

Adult↗
PubMed1976

Renal glycosuria due to gentamicin in rabbits.

Gentamicin sulfate was given to rabbits for four weeks in two dosage regimens, either 4 or 8 mg/kg subcutaneously twice a day. Two of the seven animals in each group regained nearly normal renal function after a transient rise in the level of serum creatinine, but the remainder developed severe renal failure leading to the death of all but one of these rabbits. None of the animals showed significant hyperglycemia, buy glycosuria appeared in all and was significantly correlated with the extent of renal damage. These findings demonstrate gentamicin-induced derangement of proximal tubular function and thus amplify the previously demonstrated histologic changes due to the drug. When the drug was administered twice daily, there was marked nephrotoxicity in rabbits given dosages of gentamicin only slightly higher than those employed clinically.

Acute Kidney Injury↗
PubMed1976

Induction of glycosuria and hyperglycemia by topical corticosteroid therapy.

A patient with psoriasis is described who had an abnormal response to the glucose tolerance test without other evidence of diabetes and then developed postprandial hyperglycemia and glycosuria during a period of topical administration of a corticosteroid cream, halcinonide cream 0.1%, under occlusion. A second patient with a similar glucose tolerance test result showed postprandial hyperglycemia when treated similarly with betamethasone valerate cream 0.1%. Two additional patients with midly abnormal responses to glucose tolerance tests showed no evidence of altered glucose metabolism when treated with halcinonide cream in a similar manner.

Administration, Topical↗