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At least 19 recordsLinked to original sources
PubMed1975

Radiotherapeutic management of cancer of the glottis, University of Virginia, 1956-1971.

All patients with cancer of the glottis treated by radiotherapy with curative intent at the University of Virginia from 1956 through 1971 have been reviewed. Follow-up is complete through December, 1973. Results are presented by both stage and treatment policy and indicate that with our present methods of management a high degree of local control is achieved. The complications of treatment are examined, particularly those arising as a result of combined radiotherapy and surgery. A small number of cases have been salvaged following local recurrence and these are described in detail. Particularly striking has been the effectiveness of radiotherapy in the treatment of advanced (Stage III and IV) lesions. In this group 58 percent of the patients survive with their larynges intact. Considering the poor general condition and advanced nature of the lesions in these cases this result is important and may indicate the nature of future trends in treatment, namely radiotherapy, with surgery held in abeyance until there is overt recurrence.

Carcinoma, Squamous Cell↗
PubMed1977

[Modification of surgical reconstruction of the glottis].

A personal modification to Staffieri's technique is presented. This change respects the principles of the operation but is different on the practical performance in order to avoid the incontinence of the neo-glottis. A partial decartilagination of the tracheal or crico-tracheal stump over the definitive tracheostome is performed, so that it can be funnel shaped and idoneus to the end to lateral anastomosis with the mucous membrane of the ipopharinx.

Glottis↗
PubMed1978

[Partial surgery of carcinomas of the glottis. Results and prognosis (author's transl)].

The authors present a computerized study of the prognosis of 132 cases of carcinoma of the glottis treated by vertical, partial surgery and seen over a period of 1 to 15 years at the Laennec Hospital. After defining the percentage survival at 3.5 in 10 years, the authors studied the causes of death and showed that, after 5 years, it is still deaths due to malignant recurrence which influenced the vital prognosis. These local, lymphnode and metastatic oncological failures are subsequently analyzed on the basis of clinical, surgical and histological parameters as well as in terms of the course of the disease. Such analysis makes it possible to draw the distinction between local recurrence and a second local tumor localization, and pulmonary metastases from a second pulmonary localization. Finally, the prevention of rare lymphnode recurrences is considered in terms of specific surgery for this purpose.

Chronic Disease↗
PubMed1975

Carcinoma of the laryngeal glottis therapy and end results.

The end results of 264 patients with vocal cord carcinoma treated by either surgery or radiation therapy at the University of Illinois from 1955 to 1972 are analyzed. Stage I glottic carcinoma can be cured by either surgery or radiation alone (86 percent and 80 percent). Stage II glottic cancer treated by surgery has achieved survival rates of 70 percent. The five-year end results of Stage III glottic cancer are 49 percent for surgery and 30 percent for radiation. The management of glottic carcinoma, according to anatomic site and indications for various modalities are discussed.

Carcinoma↗
PubMed1975

Analysis of surgical therapy for epidermoid carcinoma of the laryngeal glottis.

Four hundred sixty-three patients with glottic carcinoma were treated by surgical techniques with or without preoperative irradiation. Two hundred eighty-one had hemilaryngectomy and 182 total laryngectomy procedures. The overall cure rate for the hemilaryngectomy group was 91 percent and 80 percent for the total laryngectomy group, with an overall cure rate of 87 percent. Our observations support the fact that Stage I glottic carcinoma has slightly better prognosis when treated by hemilaryngectomy. Stage II and III lesions have a significant improvement in cure rate and survival when treated with combined preoperative irradiation and partiall vertical laryngectomy or total laryngectomy than by irradiation alone.

Carcinoma, Squamous Cell↗
PubMed1975

[25 years experience with glottis widening surgery in our clinic (author's transl)].

Between 1949 and 1974, 137 patients with bilateral vocal cord paralyses were operated upon in our Department. In 127 cases King's method of extralaryngeal lateral fixation of the vocal cord or a modification thereof was executed on one or both sides. The modification consisted of securing the lateral-fixating suture around the superior thyroid cornu. This produces an additional displacement of the vocal cord in the vertical plane which provides good respiratory function in spite of only moderate lateral displacement of the cord. In seven cases endolaryngeal arytaenoidectomies and submucus hemicordectomies using Kleinsassers' technique were performed. In three cases endo- and extralaryngeal methods were combined. 120 (87.6%) of all patients could be decannulated. After unilateral extralaryngeal lateral cord fixation, 77.2% of patients could be decannulated within three weeks following operation. Operative results were analysed according to respiratory and vocal function two years postoperatively. After unilateral lateral cord fixation, breathing was good or sufficient in 73.6% of cases and insufficient in 26.4% of cases. The voice was normal or dysphonic in 86% of cases while aphonic in 14% of cases. Among the causes of bilateral vocal cord paralysis, primary strumectomies and operations for recurrent goiter were predominant (95%). All patients were tracheotomized before or after the operation. Two years postoperatively, incidental tracheal stenosis was noted in 73% of all patients. This was insignificant to moderate in 63.5% of cases and severe in 9.5% of the cases.

Adult↗