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At least 19 recordsLinked to original sources

Benign migratory glossitis in patients with juvenile diabetes.

The prevalence of tissue type HLA-B15 has been shown to be higher in atopic patients with benign migratory glossitis and in patients with insulin-dependent diabetes mellitus than it is in the general population. Despite this apparent link, the possible relationship between benign migratory glossitis and insulin-dependent diabetes mellitus does not appear to have been investigated previously. This study of 87 diabetic patients and 105 age- and sex-matched nondiabetic control subjects revealed a fourfold increase in the prevalence of benign migratory glossitis in the diabetic group. These results suggest that benign migratory glossitis may be linked to diabetes mellitus and that further investigation of this association is warranted.

Adolescent

Median rhomboid glossitis associated with amyloid deposition.

There are some controversies over the pathogenesis and clinical features of median rhomboid glossitis. A case of median rhomboid glossitis associated with amyloid deposition was presented. Clinically there was no organ involved in amyloid other than the tongue. It was suspected that median rhomboid glossitis occurred first and that amyloid was induced later.

Amyloid

Median rhomboid glossitis: secondary to colonisation of the tongue by Actinomyces (a case report).

Median rhomboid glossitis is an inflammatory lesion of the tongue, now believed to be secondary to candidiasis. We document a case of median rhomboid glossitis with heavy colonisation by Actinomyces in a 60-year-old male. We propose that Actinomyces, like Candida, induces pseudoepitheliomatous hyperplasia of the mucosa of the tongue and florid inflammatory hyperplasia of the underlying connective tissue, resulting in the characteristic elevated lesion. Actinomyces has not earlier been implicated as a cause of median rhomboid glossitis.

Actinomyces

Laboratory measurements of nutritional status as correlates of atrophic glossitis.

OBJECTIVE: To perform a comprehensive laboratory assessment of nutritional status in two elderly patients selected for the presence of atrophic glossitis, a classic physical sign of malnutrition. DESIGN: Case report. SETTING: Inpatient internal medicine ward at the William S. Middleton Memorial Veterans Medical Center, Madison, Wisconsin. MEASUREMENTS AND MAIN RESULTS: Blood specimens were analyzed by the Nutrition Evaluation Laboratory at the USDA Human Nutrition Research Center on Aging at Tufts University. Both subjects had biochemical evidence of protein-calorie malnutrition and were deficient or marginally deficient in several vitamins and trace minerals. CONCLUSIONS: Much work needs to be done to determine the sensitivity and positive predictive value of the classic physical signs of malnutrition as predictors of low biochemical levels and adverse clinical outcomes. The presence of atrophic glossitis should prompt the clinician to consider a basic nutritional assessment.

Aged

Median rhomboid glossitis: not a misnomer. Review of the literature and histologic study of twenty-eight cases.

A series of twenty-eight cases of median rhomboid glossitis were studied histologically. Of these twenty-eight cases, 85 percent showed fungal hyphae in the parakeratin layer. The literature is reviewed, and additional evidence is presented to support the theory the median rhomboid glossitis is not a developmental condition but the clinical expression of a localized chronic fungal infection.

Adult

Median rhomboid glossitis caused by Candida?

The etiology and pathogenesis of median rhomboid glossitis have been subjects of controversial discussions for a long time. In recent years, the possible role of Candida albicans has been stressed. The findings in 18 patients with median rhomboid glossitis only support partly the hypothesis of Candida albicans being an important etiologic factor.

Adult

Candida albicans in median rhomboid glossitis. A postmortem study.

To investigate the possible rôle of Candida in median rhomboid glossitis, the presence of Candida was looked for both in the foramen cecum area and the lateral borders of 100 human cadaver tongues. Almost equal %s were found in both locations. Although extrapolation of findings from postmortem material to normal subjects is somewhat hazardous, the results seem to question the importance of Candida in the etiology of median rhomboid glossitis.

Adult

Glossitis of military working dogs in south Vietnam; histopathologic observations.

Glossitis, known clinically as "redtongue," was studied in tissues from 34 military working dogs (MWD) in the Republic of Vietnam. This condition was manifested grossly by loss of lingual papillae on the dorsal margins of the rostral third of the tongue. Microscopically, the principal lesions consisted of loss of filiform papillae, hemorrhage and edema in the lamina propria, acanthosis, and cellular infiltration. The cause of glossitis remains unknown at this time.

Animals

Carcinoma arising in the area of median rhomboid glossitis.

Routine soft-tissue examination of a 44-year-old Negro woman who consulted her dentist for a new maxillary partial denture revealed a depressed white lesion in the area of median rhomboid glossitis. Biopsy diagnosis of the area was well-differentiated squamous-cell carcinoma. The relation of this lesion to median rhomboid glossitis is questioned in view of previous reports.

Adult

Migratory glossitis. A clinical-histologic review of seventy cases.

The observations on seventy patients with migratory glossitis and follow-up experiences over a period of 10 years are recorded. Women represented 65.7 per cent of the total, and most cases occurred in patients over 40 years of age. In 20 per cent of the patients other anomalies of the tongue were associated, and in 20 per cent subjective complaints were associated with psychic stress. Histologic investigations showed an inflammatory reaction of the epithelium and of the underlying connective tissue. The patient must be reassured of the benign nature of the tongue lesion. At follow-up examination, the lesions were present but no malignant change was observed.

Acridines

Quantitative evaluation of Langerhans cells in median rhomboid glossitis.

Langerhans cells (LC) serve as antigen presenting cells and provide immune surveillance within epithelia. Since depression of LC number and/or function may allow tolerance to antigens, we evaluated LC in median rhomboid glossitis (MRG), a condition linked to persistent candidal infection of lingual mucosa. Material included a total of 36 cases of MRG (7 of which did not show PAS + fungi) and 6 controls. LC were identified by their expression of S-100 and HLA-DR antigens and quantified using image analysis. Equal numbers of LC were identified using S-100 + and HLA-DR + markers. The density of LC (cells/mm of basement membrane, mean +/- SD) in both PAS + MRG (2.6 +/- 1.3) and PAS-MRG (3.0 +/- 1.7) was markedly depressed compared with controls (17.2 +/- 6.4), (P less than 0.001). These findings indicate that the LC network is perturbed in MRG, and are consistent with the view that of localized defect in immune surveillance may contribute to persistent fungal infection of the oral mucosa.

Candidiasis, Oral

Acute atrophic glossitis after open-heart surgery.

The problem of Candida infections has become important in connection with transplant surgery and immunosuppression. To clarify the source of the postoperative acute atrophic glossitis (AAG) commonly seen in our department of cardiac surgery, 33 patients admitted for coronary artery bypass or valve replacement underwent clinical and microbiologic investigation before and after operation. None showed signs of AAG preoperatively, but 12 had cultures positive for Candida albicans, and in all 12 AAG appeared postoperatively. Six of the 21 patients with preoperatively negative cultures likewise had postoperative AAG. All 18 affected patients responded well to local nystatin treatment. No patient had disseminated candidiasis.

Acute Disease

Ulcerative glossitis. A facet of feline panleukopenia.

The clinical findings and the macroscopic and microscopic lesions in a kitten which died during an outbreak of ulcerative glossitis in a cattery are described. A brief review of the literature is given to support the theory that the virus of feline panleukopenia may well be the aetiological agent in this outbreak.

Animals

Symptomatic benign migratory glossitis: report of two cases and literature review.

Benign migratory glossitis (geographic tongue) is a common clinical finding in routine pediatric dentistry. The condition usually discovered on routine clinical examination, appearing as an asymptomatic, ulcer-like region on the dorsum of the tongue. The lesion may recur at different sites on the tongue, creating a migratory appearance, and in many cases, will resolve completely. The presentation of symptomatic geographic tongue in children is rare. This article presents two cases of symptomatic geographic tongue. Both children presented with a chief complaint of significant oral pain which was affecting daily activity, eating, and sleeping. Both patients presented with a classical clinical presentation of ulcer-like regions on the dorsum of the tongue in which the filiform papillae were denuded. Successful management was achieved with topical and systemic antihistamine. The clinician should be aware that this condition may be symptomatic in children.

Age Factors

Radiographic contrast medium--induced glossitis.

A new complication of intravenous radiographic contrast medium administration is recognized: severe glossitis. The pathophysiology of adverse reactions to contrast media is briefly reviewed.

Diatrizoate