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At least 19 recordsLinked to original sources

[Clinical and pathological characteristics of gastric stump cancer and recurrent gastric stump cancer].

OBJECTIVE: To study early diagnosis and rational treatment of gastric stump cancer and recurrent gastric stump cancer. METHODS: The data of 27 patients with gastric stump cancer and 23 patients with recurrent gastric stump cancer were analysed retrospectively during the past 20 years based on their clinical and pathological findings. RESULTS: The onset time was 10 years or more for gastric stump cancer and less than 10 years for recurrent gastric stump cancer after gastrectomy. Gastroscopy was better than double contrast radiography in diagnosis. Partial resection of gastric stump was performed for patients with early cancer at the anastomotic stoma of gastrojejunostomy. Total resection of gastric stump was made for other patients. Lymph node of the mesojejunum were dissected routinely because their metastasis rate was about 40.0% in patients with cancer of anastomotic stoma. The effect of surgical treatment was poor for patients with advanced cancer. CONCLUSIONS: Regular gastroscopy is useful in detecting gastric stump cancer in patients with gastric cancer after gastrectomy, or in those years after removal benign. Malignancy was more evident in recurrent gastric stump cancer than in primary gastric cancer. Prognosis is good for early stage cases and poor for late stage cases after surgical treatment.

Adult↗

Risk of gastric stump carcinoma after gastric resection for benign ulcer disease.

This follow-up study concerns 537 patients who underwent gastric resection for gastric or duodenal ulcer disease 10-13, 21-22, or 31-32 years ago. 12 (2.2%) gastric stump carcinomas were found. The development of gastric stump cancer among these patients was compared with the development of gastric cancer in a general Finnish population. In the oldest male follow-up group the observed: expected ratio for cancer was 9:3.5. This was statistically almost significant (p less than 0.05). No statistical difference could be seen in the other follow-up groups. Gastric stump carcinoma showed a strong male preponderance, with a male:female ratio of 11:1. The primary ulcer disease, whether gastric or duodenal, had no influence on the development of gastric stump carcinoma. Endoscopic screening is recommended for all male patients operated on aged 45 years or younger when 15 years have elapsed since the original gastric operation.

Adolescent↗

Duodenogastric reflux and gastric stump carcinoma.

Gastric stump carcinoma after gastric surgery for benign disease is now widely recognized as a distinct clinical entity. The stump carcinoma was often found to be localized to the anastomosis, known to be the site with severe duodenogastric reflux. For this reason, duodenogastric reflux, including the reflux of bile and pancreatic juice, after a Billroth II procedure for benign disease is frequently discussed as an important factor related to the development of stump carcinoma. Many experiments have implicated bile acids, the main component of the duodenal juice, in gastric carcinogenesis. In particular, rat models without the use of the carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG), showed adenocarcinoma in the remnant stomach that was related to the severity of duodenogastric reflux. However, human data are, inevitably, much less consistent. Whether the incidence of stump carcinoma is higher than that of gastric carcinoma in general is still controversial. Concerning the histogenesis of stump carcinoma after benign disease, a relationship between gastritis cystica polyposa (GCP) and gastric type adenocarcinoma has been suggested. Recently, the population at risk of gastric stump carcinoma for benign disease has been diminishing significantly, and the incidence of gastric stump carcinoma after surgery for malignant disease has been increasing. The influence of duodenogastric reflux in the gastric remnant after malignant disease may differ from its influence in the gastric remnant after benign disease. Further clinical study is needed to elucidate the pathogenetic factors involved in gastric stump carcinoma.

Anastomosis, Surgical↗

Laparoscopic Billroth II distal subtotal gastrectomy with gastric stump suspension for gastric malignancies.

BACKGROUND: Laparoscopy has played an ill-defined role as a diagnostic tool for the staging of gastric and other intra-abdominal malignancies for a long time. The widespread use of the laparoscopic approach for the treatment of some benign abdominal diseases, such as biliary lithiasis and gastroesophageal reflux disease, has encouraged the authors toward its use in the treatment of malignant gastric neoplasms, both for palliation and for curative surgery. METHODS: A five-puncture technique for laparoscopic distal subtotal gastrectomy, omentectomy, division of the left gastric artery at its origin, and D1 lymph node dissection has been developed by the authors, and is fully depicted and discussed. Reconstruction of digestive continuity is achieved through a posterior transmesocolic side-to-side stapled gastrojejunostomy, facilitated by an original method of suspension of the gastric stump to the anterior abdominal wall. RESULTS: In a preliminary series of 10 cases, this technique was demonstrated to be safe, showing no mortality, and having morbidity rates comparable to those of open surgery. CONCLUSION: The operation is effective, with a mean number of resected nodes comparable to that usually achieved in open surgery, and no cases of conversion to laparotomy.

Abdominal Muscles↗

[High relative risk of gastric stump cancer in young gastric resection patients].

In a large necropsy series, 31 cases of gastric stump cancer were found among patients operated for gastric or duodenal ulcer since 6 years or more. In the same series, there were 331 gastric cancer cases among patients without previous gastric surgery for benign disease. Overall age- and sex-specific relative risk for stump cancer in previously resected patients was 1.5; however, the relative risk was 2.5 in the patients operated below age 45, and it was only 0.6 in the patients resected over that age. The relative risk of stump cancer in the former group of patients was two- or three-fold than in the latter, at correspondent intervals of time since resection too. In the present material, the age at surgery appears to be a more important factor in determining the relative risk than the time interval since surgery.

Adult↗

[Cancer of the gastric stump after duodeno-gastric resection].

Carcinoma of the gastric stump in patients who have undergone resection for duodenal and gastric ulcer represents a rare event which poses considerable diagnostic and therapeutic problems. 7 personal cases are examined, particular attention being paid to the utility of endoscopy, together with sampling for cytological and histological examinations, by comparison with radiology. Endoscopy in the present cases have confirmed the high positivity obtainable with transendoscopic cytological sampling using the brushing technique. The technique should therefore become routine in the study of patients undergoing gastric resection.

Aged↗

[Effect of different types of food loads on the rate of emptying of the gastric stump in patients with the dumping syndrome after gastric resection].

The influence of carbohydrate, carbohydrate-fatty and protein test breakfasts on the rate of gastric stump evacuation was studied in 62 patients with dumping syndrome of mild and moderate severity, using the x-ray method developed by the authors. It has been established that in patients with dumping syndrome carbohydrate and carbohydrate-fatty food is most quickly evacuated from the gastric stump. Doubled amount of fat in the carbohydrate-fatty breakfast (up to 40 g) induced no significant deceleration in the gastric stump evacuation, moreover, in some cases its evacuatory function was accelerated. Intake of mineral water before breakfast did not noticeably influence the rate of gastric stump evacuation after carbohydrate and carbohydrate-fatty breakfasts, and significantly decelerates the gastric stump evacuation after protein breakfast.

Adult↗

[Problems in the diagnostic of primary gastric stump cancer and recurrences of gastric cancer. A comparison of X-ray diagnostic and endoscopy (author's transl)].

X-ray findings and gastroscopic findings of patients with primary gastric stump cancer and recurrences of gastric cancer are compared. These findings are compared with the observations of operations. The reasons of false diagnoses and doubtful tentative diagnoses were analyzed. In the analysis of X-ray pictures especially the benign operative caused and the postoperative alterations of the wall and mucosa of the stomach must delimit from infiltrative and polypous increasing tumors. The postoperative control examination may be valuable for the diagnosis, because it gives the possibilities for comparison. Roentgenography in double contrast relieves the diagnosis. Stenosing processes of the cardia and anastomose causes difficulties in differential diagnosis in gastroscopy opposite to scared alterations. The aimed biopsy improves the tumor protection. Both examination techniques shows difficulties in recognition of recurrences, which develop from the duodenal stump. Only a special examination technique leads to an improvement of the results. The instruction and experience of the examiner, the knowledge of tumor diagnostics and of the methods of operations and of the postoperative alterations are for the diagnosis of these processes of decisive importance. X-ray examination and endoscopy are two supplementing examination methods.

Endoscopy↗

Gastric stump carcinosarcoma with rhabdomyosarcomatous differentiation.

Gastric carcinosarcoma is an unusual tumor and its occurrence in the gastric stump is extremely rare. A report is presented here of a unique case of gastric stump carcinosarcoma with rhabdomyosarcomatous differentiation in a 74-year-old man. The patient had undergone partial gastrectomy with gastrojejunostomy (Billroth II method) 30 years previously. The tumor had both adenocarcinoma and sarcoma components, and an immunohistochemical study suggested a focal transition between these components. The main sarcomatous components showed fibrosarcomatous features with a scattered distribution of rounded tumor cells, whose rhabdomyosarcomatous differentiation was immunohistochemically determined. Ultrastructural examination supported the rhabdomyosarcomatous natures. Experience with the present tumor indicates that carcinosarcoma with rhabdomyosarcomatous differentiation can occur in the gastric stump and that this disease is capable of aggressive behavior.

Aged↗

[Cancer of the gastric stump].

627 cases of gastric cancer treated surgically during the last 5 years, at the Hospital Nacional "Edgardo Rebagliati Martins" from Instituto Peruano de Seguridad Social (Lima-Perú) were revised. 4 of the patients had been operated before of hemigastrectomy or antrectomy with pyloroplasty for peptic ulcer. The time between the first operation and diagnosis of cancer of the gastric stump was more than 20 years. 3 of these cases were able to be resected. The international incidence of cancer in the gastric stump is 1.1% to 9.2% according to different authors. The risk is higher after 15 years. In the pathogenesis are advocated the lower gastric acidity, biliary reflux, the presence of bacteria, the formation of nitrosamines, intestinal metaplasia, etc. Is necessary to perform periodic endoscopic survey in patients who were treated surgically of peptic ulcer with antrectomy or hemigastrectomy with more than 15 years of evolution.

Adenocarcinoma↗