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At least 19 recordsLinked to original sources

High prevalence of gynecologic disease among hospitalized women with human immunodeficiency virus infection.

We offered standardized gynecologic examinations to consecutive women admitted to an AIDS-designated inpatient medical service; 65 (97%) of 67 women consented to the examination. The median CD4+ T lymphocyte count was 54/mm3. Only 9% of the women were admitted for primary gynecologic or genitourinary diagnoses; however, on evaluation, 83% of these women had gynecologic disease. The overall prevalences of vaginitis, cervical dysplasia, genital condylomata, genital herpes, and pelvic inflammatory disease were 51%, 45%, 23%, 20%, and 5%, respectively. Unexpected findings included adenovirus infection and foscarnet-associated genital ulcerations (two cases each). For predicting disease, gynecologic symptoms had a sensitivity of 76% and a positive predictive value of 95% but a negative predictive value of only 41%. Our results document the high prevalence of comorbid gynecologic disease among women infected with human immunodeficiency virus (HIV). Because of the inability to fully predict disease by symptom history, it is imperative that comprehensive gynecologic evaluation be offered routinely to all HIV-infected women hospitalized for acute medical illnesses.

Adult↗

[Modern aspects in the diagnosis and treatment of gynecologic diseases in childhood and adolescence].

Gynecological problems in juvenile and adolescent age deserve a special attention. Disorders appearing at this age are not identical with those developing in adults. Diagnostics and therapy of gynecological diseases in juvenile and adolescent age are far more complicated than the same procedures with adult women, while instruments and examination protocols have to be adjusted to the age of patients. To maintain the purpose of preserving the generative function and sexuality of an adult woman early detection and treatment of gynecological diseases of juvenile age are essential. The paper focuses at the analysis of the most frequently appearing disorders in juvenile and adolescent age: vulvovaginitis, foreign parts in vagina, development anomalies, synechia vulvae and injuries. It is essential to recognize certain diseases in order to prevent possible consequences in older age. Following diseases appearing in adolescents have also been analyzed: menstruation disorders (with an emphasis on menstruation disorder influenced by body weight), sexually transmitted diseases, pregnancy detection and complications.

Adolescent↗

[Prognosis in gynecologic diseases].

Besides early diagnosis, the prognosis of gynecological disease is dependent on the state of the urinary tract. Mainly tumours and site anomalies of the female genital system as well as endometriosis and chronic-inflammatory masses of the appendages lead to malfunction of urinary bladder, ureter and kidneys. Ureteric changes are seen in 3 to 55% of genital tumours and in 20 to 40% of cases of endometriosis. Ureteric and kidney dysfunction can occur even more often in longstanding site anomalies. Typical renal complications of gynecological diseases are pyelonephritis, pyelectasy and hydronephrosis. Their frequency lies between 8 and 40% depending on kind and duration of the underlying disease. The figures shown, indicate that renal and ureteric changes sometimes are more serious than the genital disease. Improvement of prognosis can only be achieved by early recognition of the underlying gynecological disease together with the timely proof of renal and ureteric dysfunction.

Cause of Death↗

Surgery by minilaparotomy in benign gynecologic disease.

A new, minimally invasive technique for the management of benign gynecologic disease is proposed. With the patient in a steep Trendelenburg position, access to the pelvis is gained through a minimal suprapubic incision (4-9 cm) beneath the pubic hair line. The subcutaneous fat is incised in a cranial direction and the abdominal fascia is opened 2-3 cm above the skin incision. The peritoneum is opened manually and two or three Deaver retractors replace the traditional self-retaining retractor. Continuous repositioning of the retractors permits the operative window to be focused always on the surgical field. This technique can be performed only if the following criteria are met: use of narrow and light instruments; exteriorization of the affected organs; combined, unidirectional maneuvering of all the retractors; and prompt hemostasis by electrocoagulating forceps. Among 78 inpatients with benign gynecologic diseases who underwent surgical treatment with this approach, the feasibility rate was 96% and no intraoperative complications or severe postoperative morbidity were observed. Pelvic surgery by minilaparotomy is a feasible and safe approach in the treatment of benign gynecologic disease.

Feasibility Studies↗

Gastrointestinal tract involvement by gynecologic diseases.

Involvement of the gastrointestinal tract by gynecologic disease processes-endometriosis, gynecologic neoplasms, inflammatory processes, and complications from radiation therapy or surgery for gynecologic tumors-may mimic primary gastrointestinal carcinoma on radiologic images. Endometriosis most often involves the anterior wall of the rectosigmoid colon, adjacent to the pouch of Douglas, and typically produces extrinsic mass effect on the serosa, with the overlying mucosa left intact. Direct extension of ovarian cancer to the colon through the subperitoneal space produces mass effect with serosal spiculation, tethering, and fixation; annular constriction; or partial or complete obstruction. Intraperitoneal seeding of ovarian carcinoma most frequently involves the colon and is seen as extrinsic masses, often with serosal spiculation and tethering. Cervical carcinoma, which most commonly spreads by direct invasion of the pelvic side wall and adjacent structures, produces serosal spiculation and circumferential narrowing. Benign ovarian or uterine tumors are purely extrinsic and have a smooth interface with the colonic wall. Tubo-ovarian abscesses are difficult to differentiate from cystic ovarian neoplasms or endometriomas. Radiation colitis causes narrowing of the rectum with intact mucosa and can be differentiated from recurrent tumor, unlike radiation-induced injury of the small bowel, which may be difficult to distinguish. Surgical adhesions produce a discrete transition point between dilated bowel proximally and nondilated distal bowel. Familiarity with the varied patterns of gastrointestinal tract involvement is important for accurate interpretation of imaging studies.

Diagnosis, Differential↗

Gynecologic disease in women infected with human immunodeficiency virus type 1.

Gynecologic disease is commonly encountered in women infected with the human immunodeficiency virus (HIV). The clinical course of cervical intraepithelial neoplasia, invasive cervical cancer, pelvic inflammatory disease, syphilis, and vaginal candidiasis may be altered by HIV infection and may be refractory to standard treatment, especially with increasing degrees of immune suppression. Careful screening for gynecologic disease and vigilant surveillance for treatment failure are important in the care of women infected with HIV.

Acquired Immunodeficiency Syndrome↗

Prevalence of Mycoplasma hominis in patients with gynecologic diseases and abortion in the 2nd--3rd month of pregnancy.

The presence of Mycoplasma hominis was investigated in 100 patients with gynecologic diseases, 20 infertility cases and 50 cases of abortion in the 2nd--3rd month of pregnancy. M. hominis could be isolated from the vaginal secretions of 20 patients with gynecologic diseases and of 3 infertility cases. Eighteen M. hominis isolates were recovered from 13 patients with abortion (8 strains from the placenta and 10 from vaginal secretions). High titers (1/64--1/512) of complement fixing antibodies to M. hominis were found in 16 patients with gynecologic diseases, 12 infertility and 17 abortion cases.

Abortion, Spontaneous↗

Surgery for malignant gynecologic disease.

The surgical management of malignant gynecologic disease continues to evolve as more is learned about the natural history and biology of these neoplasms. Whereas curing malignancies remains the ultimate goal of most surgical procedures for gynecologic cancers, the importance of quality of life cannot be ignored. Surgical procedures that enhance the quality of life without compromising cure continue to be explored. In vulvar cancer, the disfiguring classical radical vulvectomy is being replaced by more conservative procedures. As anesthetic techniques and postoperative care continue to improve, the role of radical surgery for invasive and recurrent cervical cancer has been extended to include older women. Ovarian cancer continues to be the most lethal of all gynecologic malignancies, and the role of aggressive primary and secondary cytoreduction continues to be defined. The new International Federation of Gynecology and Obstetrics staging system for endometrial cancer has generated controversy regarding the benefits and morbidity associated with surgical staging.

Female↗

Cytopathological findings on vaginal Papanicolaou smears after hysterectomy for benign gynecologic disease.

BACKGROUND: Periodic, routine Papanicolaou smears of cells from the vagina are commonly examined in women who have undergone a hysterectomy for benign gynecologic disease. The benefits of this method of screening are not known. METHODS: We analyzed Papanicolaou smears obtained from the vaginal apex (cuff) in 6265 women at Charity Hospital in New Orleans between January 1, 1992, and December 31, 1994. Of the 10,595 vaginal smears, an estimated 9610 were obtained during follow-up examinations of 5682 women who had undergone hysterectomy for benign gynecologic disease. RESULTS: Among these 9610 vaginal smears, 104, from 79 women, were abnormal. The abnormal smears were categorized according to the findings, as follows: atypical squamous cells of undetermined significance, 52 (0.5 percent of all smears); low-grade squamous intraepithelial lesion, 44 (0.5 percent); high-grade squamous intraepithelial lesion, 6 (0.1 percent); and squamous-cell carcinoma, 2 (0.02 percent). In five women, biopsies revealed vaginal intraepithelial neoplasia type I or II; there were no biopsy-proved cases of vaginal cancer. The probability of an abnormal Papanicolaou smear in this group of women was 1.1 percent, and the positive predictive value of the Papanicolaou test for detecting vaginal cancer was 0 percent (95 percent confidence interval, 0 to 33 percent). CONCLUSIONS: The prevalence of abnormal findings on cytopathological examination of vaginal Papanicolaou smears after hysterectomy for benign gynecologic disease is extremely low.

Adult↗

Applications of computed tomography in gynecologic diseases.

Computed tomography (CT) has evolved to play a significant role in the assessment of gynecologic diseases, primarily gynecologic malignancies. The cross-sectional display provides clear depiction of the female pelvic organs, viscera, and their surrounding fat planes. In the evaluation of certain pelvic malignancies, CT has become a fundamental study in the initial staging and subsequent follow-up of patients undergoing chemotherapy and radiation treatment. This manuscript describes and illustrates the role of CT in evaluating a spectrum of gynecologic pathology.

Female↗

[Laparoscopy in the differential diagnosis and treatment of acute appendicitis and acute gynecological diseases].

Laparoscopy was used in differential diagnostics of acute appendicitis in 524 female patients. Acute gynecological diseases were diagnosed in 123-of them, inflammatory processes in appendages being most frequent. The laparoscopic technology allowed not only to avoid diagnostic errors in all the cases, but also to take all necessary surgical measures. The effectiveness of laparoscopic operations for acute gynecological diseases was confirmed by the absence of complications and recovery within short terms.

Acute Disease↗

[Vocal tract disorders in women with hormonal gynecological diseases].

The paper analyzes the incidence rates and specific features of vocal apparatus disorders in dyshormonal gynecological diseases in the reproductive and menopausal periods. It presents a complex procedure for diagnosis and treatment, which includes the management of the patient by a phoniatrist jointly with an endocrinological gynecologist, a psychoneurologist, and a phonopedist. Drugs for correcting sexual hormone levels, psychoemotional status, venous tone, breathing exercises and phonopedic classes by using biological feedback, and physiotherapeutical methods of treatment have been used. Indications and contraindications for the use of hormonal drugs in the treatment of dyshormonal gynecological diseases in individuals of voice-and-speech professions are considered.

Adult↗