Effect of profound gastric hypothermia (gastric freezing) upon various phases of gastric secretion.
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The factors involved in the production of significant mucosal injury in gastric freezing were studied in a group of dogs. The study showed that diffusion of the inflowing coolant solution to prevent the "jet thrust" phenomenon on the anterior stomach wall minimizes the gross mucosal lesion. Use of a newly designed infusion device permitted freezing for 60 minutes without significant mucosal injury.
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Measurements of temperatures inside the stomachs of humans by means of thermister probes introduced with the balloon used in cryotherapy indicated that the mucosa does not undergo freezing in this procedure.
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