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At least 19 recordsLinked to original sources

Body composition and expiratory reserve volume in female gymnasts and runners.

Previous research in this laboratory demonstrated a reduction in expiratory reserve volume of the lungs (ERV) with increasing body fatness (%F, by densitometry). The present study was done to determine if smaller ERV values could be demonstrated in lean female athletes with greater than normal upper-body muscle development. Expiratory reserve volume, vital capacity (VC), and segmental body volumes by densitometry were measured in members of two collegiate women's teams--gymnastics (G) (N = 10) and track (R) (N = 10). The runners provided a control group by being similar to gymnasts in age, weight, and body fatness, but they did not engage in upper-body weight training or gymnastic exercises. The two groups were not significantly different in body weight (means G +/- SD = 53.0 +/- 6.1 kg; means R = 50.8 +/- 4.6 kg) or %F (means G = 16.8 +/- 3.2%; means R = 14.8 +/- 3.8%), but R subjects were taller (means = 165.4 +/- 5.5 cm vs 158.7 +/- 4.8 cm, P less than 0.01). Expiratory reserve volume, expressed as a percent of VC, (ERV X VC-1) 100, was significantly (P less than 0.001) less in the gymnasts (means +/- SD = 29.7 +/- 7.1) as compared to the runners (43.1 +/- 6.4). All other lung capacities as volumes were comparable in both groups. Arm and thorax volumes indicated greater upper-body size in the G subjects (arm volume, means +/- SD of G = 4.8 +/- 0.6 liters, of R = 4.0 +/- 0.6 liters, P less than 0.01; thorax volume, means +/- SD of G = 7.8 +/- 1.4 liters, or R = 5.6 +/- 1.0 liters, P less than 0.001).(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗

Body composition and the expiratory reserve volume in lean and obese men and women.

The expiratory reserve volume (ERV) of the lungs was determined in 40 women and 34 men over a wide range of age (18-58 years) and percent body fat (3.6-48.6 percent). A negative correlation with percent body fat resulted when the ERV values were expressed as a percent of the vital capacities (ERV/VC . 100). The regression equations were: for women, ERV/VC . 100 = 49.5 -0.63 %F, r = -0.70, SEE = 7.77; for men, ERV/VC . 100 = 48.7 -0.80 %F, r = -0.78, SEE = 6.05. No significant correlation with age or height was found for either sex.

Adipose Tissue↗

Laminoplasty improves respiratory function in elderly patients with cervical spondylotic myelopathy.

Respiratory insufficiency after acute cervical trauma is well documented, but the relationship between respiratory function and chronic lesions, such as cervical spondylosis, has received scant attention. This clinical study investigated the effect of cervical spondylosis on respiratory function in 12 patients over 65 years of age who underwent expansive laminoplasty. Functional and neurological status were assessed using the Japanese Orthopaedic Association (JOA) scale and Neurosurgical Cervical Spine Scale (NCSS). To assess the effect of laminoplasty on respiratory function in patients with cervical spondylotic myelopathy, lung volumes including vital capacity, tidal volume (TV), inspiratory reserve volume, expiratory reserve volume, inspiratory capacity, and forced expiratory volume were measured by spirometer before surgery and 6 months after surgery. The arterial blood gas values were also measured before and after surgery. All patients showed functional improvement after surgery, and neurological examination 6 months after surgery revealed a significant improvement in both JOA scale and NCSS scores (p < 0.001). There were no significant differences in most lung volumes, but TV (p = 0.039) at 6 months after surgery showed a significant increase compared to before surgery. PCO2 also showed a significant reduction after surgery (p = 0.047). This limited study revealed that laminoplasty improved respiratory function in patients over 65 years of age with cervical spondylotic myelopathy. Lung volume measurement may be one method to estimate spinal cord function after a surgical procedure.

Aged↗

Body composition and the expiratory reserve volume of pre-pubertal lean and obese boys and girls.

Previously, we examined the expiratory reserve volume (ERV) of the lungs as a function of percentage body fat in an adult population (age range 18-58 years). A negative correlation resulted when ERV (expressed as a percentage of vital capacity, (ERV/VC) x 100) was regressed on percentage fat for both sexes. In the present study, similar comparisons were made for 33 pre-pubertal boys and girls (aged 7-12.5 years). The regression equation for the boys ((ERV/VC) x 100 = 44.2 - 0.56%fat, r = -0.77, P = 0.002) was similar to that of the adult men ((ERV/VC) x 100 = 48.7 - 0.80 %fat, r = -78) and women ((ERV/VC) x 100 = 49.5 - 0.63 %fat, r = -0.70). However, the girls studied did not follow the same pattern. In this group of pre-pubertal girls, a significant increase in (ERV/VC) x 100 with increasing body fatness was seen ((ERV/VC) x 100 = 29.3 + 0.19 %fat, r = 0.48, P = 0.03). In all four groups, no correlation was seen with age or height. Whereas there was a significant correlation between weight and (ERV/VC) x 100 in the adults, no such relationship was evident in the younger subjects. In pre-pubertal obese girls limited upper body muscle development, perhaps as a result of limited physical activity, may explain the different relationship between ERV and body fatness.

Body Composition↗

A simple spirometric clue to asthma: airways obstruction suggested by negative or reduced forced expiratory reserve volume despite normal FEV1-FVC ratio.

I report on 25 asthmatic patients in whom airways obstruction was not detectable by conventional spirometric indices, but was suggested by a reduced or negative forced expiratory reserve volume (FERV), that is, the ERV measured from the forced vital capacity (FVC) maneuver and preceding tidal breaths. Patients with known causes for reduced ERV were excluded. The ratio of forced expiratory volume-1 sec (FEV1) to FVC was normal or high in all 25 patients, and the forced expiratory time (FET)25-75% was normal in half (12). Using conventional spirometric algorithms, the condition of most (76%) of the patients would be interpreted as "restrictive impairment". The FERV is easily measured in a physician's office or clinic. If this simple test is to provide a clue to the presence of airways obstruction that is otherwise not demonstrable spirometrically, the FVC maneuver must be maximal and reproducible and the preceding tidal breaths, as well as the FVC, must be graphically recorded.

Adult↗

Influence of acute isocapnic hypoxia on bronchial calibre and "expiratory reserve" volume in dogs.

The effects of hypoxia on bronchial calibre were investigated in anaesthetized dogs using a computer-aided forced airflow oscillation technique which derived specific lower airways conductance (sGlaw) and "expiratory reserve volume" (ERV). Measurements were made with inspired oxygen concentrations varying from 40% to 10%. sGlaw tended to be slightly reduced (indicating bronchoconstriction) by decreasing the oxygen concentration from 40% to 15%, these changes being statistically significant after the administration of atropine. ERV was unaffected by changes in oxygen concentration from 40% to 15%, but was significantly reduced during ventilation with 10% oxygen. This effect was reversed by re-oxygenation and was not abolished by prior administration of atropine. It was concluded that both bronchoconstriction and changes in lung volume may be responsible for changes in airway resistance during hypoxia.

Airway Resistance↗

Expiratory reserve volume and vital capacity of the lungs during immersion in water.

The effects of immersion by 5-cm increments on the expiratory reserve volume of the lungs (ERV) and on the vital capacity were studied in the sitting and supine positions. These effects were compared to those produced by continuous negative-pressure breathing when the subjects were in air and were counteracted by positive pressure breathing during immersion. The depth of immersion was also related to definable anatomic landmarks. In the sitting position about one-fourth of the decrease in the ERV was accounted for by the hydrostatic pressure of the water on the abdomen and the remainder by the pressure on the thorax. Immersion to the level of the spinous process of the seventh cervical vertebra was equivalent to 28 cmH2o continuous negative pressure breathing in air. In the supine position, a comparable value was 8 cmH2o. These observations agree well with those of others if differences in the levels of immersion are accounted for.

Abdomen↗

Lung volume dependence of pharyngeal cross-sectional area by acoustic pharyngometry.

Pharyngeal size and the dynamic behavior of the pharynx may be important factors in the modulation of pharyngeal airflow. There are two measures of pharyngeal function: changes in pharyngeal area with lung volume and changes in pharyngeal area in response to externally applied positive pressure. Both measurements have been used for the assessment of pharyngeal function, and both reflect pharyngeal "floppiness." The aim of the present study was to examine the relationship between pharyngeal cross-sectional area, using acoustic reflection technique, and different lung volumes (tidal volume, inspiratory reserve volume, and expiratory reserve volume), to determine whether there are differences in mechanical properties of the pharynx of normal volunteers in response to changes in intrapharyngeal pressure. The acoustic technique was used to assess the pharyngeal cross-sectional area of 40 healthy volunteers (29 men and 11 women) at tidal volume, inspiratory reserve volume, and expiratory reserve volume. In men, the mean pharyngeal area at tidal volume was 3.191 cm2, the mean pharyngeal area at inspiratory reserve volume was 2.976 cm2, and the mean pharyngeal area at expiratory reserve volume was 2.975 cm2. In women, the corresponding pharyngeal area measurements were 2.832, 2.484, and 2.492 cm2. Statistical analysis of results showed that men have a larger pharyngeal cross-sectional area and the pharyngeal airways of men and women act in a similar manner in response to changes in intrapharyngeal pressure, with men having a greater change. Examination of the pharyngeal compliance by acoustic pharyngometry adds to the potential of this technique as a tool for the evaluation of the pharyngeal airway in terms of area and dynamic behavior assessment. This may be of relevance in promotion of the development of upper airway assessment in patients with obstructive sleep apnea.

Acoustics↗

Lung function in Indian twin children: comparison of genetic versus environmental influence.

The relative contributions of genetic and environmental components in the variability of lung function measurements were studied in 54 twin pairs. Thirty pairs of monozygote (MZ) twins and 24 pairs of dizygotic (DZ) twins were examined. All measurements were made with 9-litre closed-circuit-type expirographs using standard spirometric techniques, except for peak expiratory flow rate (PFER) which was recorded with a Wright peak flow meter. Within-pair variances for inspiratory capacity (IC), vital capacity (VC), forced vital capacity (FVC), forced expiratory volume in 1 second (FEV1), forced mid-expiratory flow (FEV25-75%), forced end-expiratory flow (FEF75-85%), maximum expiratory flow (FEF200-1200ml), forced maximum voluntary ventilation MVVF) and PEFR were significantly smaller (p < 0.01) in MZ twins than in DZ twins. Tidal volume (VT), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), forced expiratory volume in 1 second as a percentage of forced vital capacity (FEV1%), and forced expiratory time (FET) were not significantly different. Within-pair correlations were all higher in MZ than DZ twins. All measurements except for VT and PEFR showed high levels of heritability (23-99%). All measurements were positively and significantly correlated with physical characteristics such as weight, standing height, surface area, arm-span, chest circumference and age, except FEV1% and FET. Residual values adjusted for physical characteristics showed similar results to unadjusted values in most cases. These data indicate that major lung function measurements are possibly influenced more by genetic than environmental factors. Genetically influenced measurements show higher levels of heritability estimates and suggest that genetic determination of lung function is possibly independent of the influence of physical characteristics.

Adolescent↗

Prediction equations for pulmonary function values in healthy young Iranians aged 8-18 years.

OBJECTIVE: Pulmonary function test (PFT) variables are dependent on height, age and gender. In addition, there is evidence of PFT variation in different ethnic groups. Prediction equations for PFT from a healthy, non-smoking, urban young population in the city of Mashhad (north-east Iran) have been derived. METHODOLOGY: Prediction equations for normal pulmonary function were derived from 336 healthy, non-smoking subjects, including 187 males (height 103-188.5 cm) and 149 females (height 104-183 cm) aged 8-18 years. The subjects underwent measurement of spirometric flow and volume. The following variables were measured: FVC, FEV1, maximal mid-expiratory flow (MMEF), PEF, maximal expiratory flow at 75, 50 and 25% of the FVC (MEF75, MEF50, and MEF25, respectively), tidal volume (VT), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), inspiratory capacity (IC), and vital capacity (VC). Regression analysis using height and age as independent variables was applied to provide predicted values for both genders. RESULTS: There were positive correlations for each pulmonary function variable with height and age. The largest positive correlations were found for FEV1 with height and age, in both genders. Comparison of PFT variables derived from the equations obtained in the present study showed significant differences to those calculated from several previously published equations (P < 0.001 for most variables). For example, the values of FVC and FEV1 derived from the equations obtained in the present study were 2.83 +/- 0.99 and 2.50 +/- 0.89 for males, and 2.41 +/- 0.54 and 2.19 +/- 0.53 for females, while the values derived from the equations of the European Community for Steel and Coal study were 3.12 +/- 1.06 and 2.62 +/- 0.89 for males and 2.79 +/- 0.67 and 3.35 +/- 0.57 for females, respectively. CONCLUSIONS: A set of PFT reference values and prediction equations for both genders has been derived using a relatively large, healthy, non-smoking Iranian young population, and has generated results that differ from several other prediction equations.

Adolescent↗

Lung function in healthy British women.

The forces expiratory volume, total lung capacity, transfer factor (diffusing capacity), and their subdivisions have been measured in 113 healthy British women aged 27 to 74 years of whom 47 were current smokers and 66 were lifetime non-smokers. The results have been analysed in terms of age, stature, mass, body fat, and smoking. In addition to their relation to stature and to age, the inspiratory capacity was positively correlated with indices of body muscle while the residual volume, expiratory reserve volume, and total lung capacity were inversely correlated with the percentage of body mass that is fat or with mass divided by the square of stature. The inverse correlation between total lung capacity and age was apparently due to the quantity of body fat increasing with age. The transfer factor and its subdivisions were inversely correlated with smoking. In this study the forced expiratory volume and vital capacity were independent of both fat and smoking; the transfer factor was independent of the physiological response to exercise. The results provide reference values for lung function in British women.

Adipose Tissue↗

Depression of respiratory function by pneumatic antishock trousers in traumatic quadriplegia.

A case of mild hypoventilation associated with an incompletely inflated pneumatic antishock suit in traumatic quadriplegia is presented. Pulmonary function studies were performed on the same patient 23 days later. Base line studies were performed and then repeated with the antishock suit inflated to 40 and then 100 mm Hg. Measurements were made of tidal volume (Vt), inspiratory reserve volume (IRV), expiratory reserve volume (ERV), forced vital capacity (FVC), forced vital capacity in one second (FEV1), and maximum voluntary ventilation (MVV). With increasing suit pressures, all parameters decreased with the exception of the ERV, which was initially zero. Traumatic quadriplegia must be added to the list of disorders in which caution must be used when considering the use of the abdominal compartment of the pneumatic antishock suit.

Accidents, Traffic↗

Physiologically and subjectively acceptable breathing resistance in divers' breathing gear.

To determine acceptable levels of breathing resistance in divers' gear, 6 subjects were exposed to varying levels of breathing resistance under demanding and realistic conditions. The immersed air-breathing subjects exercised in the prone position at 60% of their maximum oxygen uptake for 25 min in a hyperbaric chamber at 1.45 and 6.8 atm abs (145 and 690 kPa, 4.5 and 57 msw, 15 and 190 fsw). The breathing resistance ranged from minimal to 8-12 cmH2O (0.8-1.2 kPa).liter-1.s at flow rates of 2-3 liter/s. The higher resistance levels interfered with the respiration in terms of end-tidal PCO2 and dyspnea scores. There were considerable individual differences, and changes in one parameter were typically not paralleled by changes in the other. None of maximal voluntary ventilation, forced expiratory volume, expiratory reserve volume, vital capacities, or oxygen uptake was influenced by resistance. We set the maximum allowable end-tidal PCO2 at 60 mmHg and maximum dyspnea score at 1.0 on a scale from 0 (none) to 3 (severe). Based on these criteria we concluded that the external work of breathing should not exceed 1.5-2.0 J/liter in the ventilation range 30 to 75 liter/min BTPS.

Adult↗

The effects of posture on venous admixture and respiratory dead space in health.

Alveolar-arterial PO2 difference ([A-a]PO2), venous admixture, and physiologic dead space were measured in 24 healthy men and women 23 to 72 years of age in the sitting and supine positions, breathing air, breathing O2, and breathing O2 in deep breaths. In the supine (but not the sitting) position, (A-a)PO2 and venous admixture, breathing both air and O2, were more highly correlated with the difference between closing volume and expiratory reserve volume than with age. The change in (A-a)PO2 and venous admixture from sitting to lying was related to the change in closing volume minus expiratory reserve volume, during both air and O2 breathing. These results confirm previous work on the contribution of gravity-dependent airway closure to the air-breathing venous admixture. They further indicate that the same mechanism is important when O2 is breathed, and it may account for most of the alveoli that close during O2 breathing because of critically low ventilation perfusion ratios. Physiologic dead space in the supine position may be predicted by subtracting 12.5% from the normal sitting value for the same tidal volume and respiratory frequency.

Adult↗

Experimental studies of the deposition of particles in the human lungs.

Measurements of deposition, De, during steady breathing through the mouth of particles between 0.5 and 2.5 micons diameter and density 0.92 g/cm3 show that it is related to the tidal volume, VT, expiratory reserve volume, Vr, and a "normal" volume, Vro, by the formula 100 De= Vt/B+C/FD- E- Vr-Vro/A where B, C, D and E are constants which depend on particle size but do not vary from subject to subject enough to have much influence on corresponding values of De. A and and Vro are independent of particle size but relate to the individual subject, especially Vro. A new method is described of correlating the numerous experimental results, which involve six variables, and of evaluating the subject's 'normal' expiratory reserve volume, Vro, for any subject.

Aerosols↗