Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Dye Dilution Technique”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 19 recordsLinked to original sources

Reliability of echocardiography in assessing cardiac output. A comparative study with a dye dilution technique.

Because of the potential benefits froma noninvasive technique in assessing cardiac output, we compared cardiac output estimates from left ventricular echocardiograms with results obtained simultaneously by a standard technique, dye dilution in 10 healthy normal volunteers. During rest, cardiac outputs by echocardiographic and dye dilution techniques were reproducible and not significantly different. Increases in cardiac output produced by intravenous infusion of isoproterenol (15 ng/kg/min for 4 min) were accurately estimated by echocardiography in subjects whose stroke volume increased less than 40%, but were significantly underestimated when stroke volume increased more than 40%. Decreased cardiac output produced by intravenous propranolol (0.2 mg/kg) was comparable by both methods. Although echocardiography accurately estimated mean cardiac output for the group it over- or underestimated cardiac output in individual subjects. We propose that echocardiography can reliably estimate cardiac output in groups at rest and when stroke volume changes less than 40%.

Cardiac Output↗

Spontaneous portorenal shunting in portal hypertension assessed by a dye dilution technique.

Using a dye dilution technique, blood flow was measured in the right and left renal veins in 12 patients with portal hypertension. There was evidence of spontaneous shunts to the left renal vein in all cases and at least in 4 cases to the right one. Spontaneous portal systemic shunts other than via esophageal varices is probably much higher than hitherto known.

Catheterization↗

Measurement of cardiac stroke volume during cesarean section: a comparison between impedance cardiography and the dye dilution technique.

Simultaneous determination of cardiac stroke volume by impedance cardiography and the dye dilution technique was compared in ten women undergoing elective cesarean section performed under general or epidural anesthesia. The influence of delivery and the anesthetic procedures used on stroke volume determination by the two methods was evaluated and compared. The correlation coefficients for measurements performed before and during anesthesia showed little variation and were largely unchanged after delivery of the child (r = 0.90-0.97). Mean stroke volume determined by impedance cardiography was significantly (P less than 0.001) lower than mean stroke volume calculated from the dye dilution technique. However, there was no significant difference between the mean change in stroke volume determined by the two techniques during serial measurements. Impedance cardiography was found to be a safe, reliable, non-invasive technique for the measurement of changes in stroke volume during cesarean section. The ability of the impedance method to determine changes in stroke volume was unaffected by the anesthetic procedures employed or by delivery of the child.

Anesthesia, Epidural↗

Dye-dilution techniques using aminohippurate sodium: do they accurately reflect amniotic fluid volume?

OBJECTIVE: To determine whether the dye-dilution technique using aminohippurate sodium accurately measures amniotic fluid volume. METHODS: Singleton pregnancies with intact membranes undergoing a Cesarean delivery had their amniotic fluid volume assessed by the dye-dilution technique and direct measurement. RESULTS: Fifteen women were prospectively assessed. Six patients had their amniocentesis on the delivery table and nine patients at 4-24 h prior to the Cesarean delivery. The six women undergoing an amniocentesis just before delivery had good concordance between the dye-determined and direct measurement of amniotic fluid volume (r = 0.99, p = < 0.001). Among the nine women with varying times from amniocentesis to direct measurement, the correlation was not significant (r = 0.36, p = 0.08). The percentage difference between the dye-determined and directly measured amniotic fluid volume was significantly smaller in the women undergoing amniocentesis just prior to delivery (7%) than in the women with varying times from amniocentesis to delivery (37%, P < 0.001). CONCLUSION: Dye-determined amniotic fluid volume accurately reflects actual amniotic fluid volume but the dye-determined concentrations, in vivo, may undergo rapid changes.

Adolescent↗

Blood flow determination in splenorenal shunts using a dye dilution technique.

Determination of flow through splenorenal shunts performed for portal hypertension was tried in 7 patients using a dye dilution technique. Varying shunt flows were obtained. The results of the flow determinations were compared with the findings at arteriography and the cause of the varying flows could be revealed. Retrograde flow through the left ovarian vein leading to incomplete mixing was the most common source of error. The employed dye dilution techniques lends itself to shunt flow determination only if sources of error can be ruled out by arteriography.

Dye Dilution Technique↗

Compensatory hyperplasia of the human kidney evaluated by angiography and a dye dilution technique.

The renal blood flow and related variables were assessed with a dye dilution technique in conjunction with angiography of the enlarged kidney in 13 patients with unilateral disease, hypoplasia or aplasia of one kidney. The total renal blood flow, the width of the arteries, the kidney area, the vascular volume and the thickness of the cortex were all increased. The vascular resistance was decreased. The circulation time through the kidney was normal but the flow volume and most likely also the intrarenal flow velocity were increased.

Adult↗

Amniotic fluid volume assessment: comparison of ultrasonographic estimates versus direct measurements with a dye-dilution technique in human pregnancy.

OBJECTIVE: The purpose of our study was to compare the accuracy of clinical ultrasonographic techniques of amniotic fluid volume assessment with a dye-dilution technique. STUDY DESIGN: We compared amniotic fluid volume as measured by ultrasonographic techniques with a dye-dilution method in 50 women undergoing amniocentesis during the third trimester. Thirteen separate ultrasonographic techniques, including the amniotic fluid index, were evaluated with regression analysis. RESULTS: Amniotic fluid volumes as determined by dye-dilution ranged between 129 and 4444 ml. The amniotic fluid index overestimated the actual volume by as much as 88.7% at lower volumes and underestimated the actual volume by as much as 53.9% at higher volumes. CONCLUSIONS: Differences in measurement error between the other ultrasonographic methods and the amniotic fluid index did not appear to be sufficient to warrant changes in current clinical practice. A major source of error in ultrasonographic amniotic fluid volume assessment is that one-dimensional measurements are used to estimate the volume of a complex, three-dimensional object.

Amniotic Fluid↗

Comparison of the cardiac output measurements with electromagnetic flowmeter and dye-dilution technique in dogs, with a note on the comparison between radiocardiography and ear-dye method in man.

There are relatively few studies and opinions are still divided as to the agreement between the electromagnetic flowmeter and dye-dilution technique in measurements of cardiac output in animals. Of 22 pairs of cardiac output measurements performed with an electromagnetic flow probe applied to the root of aorta in open-chest, anesthetized dogs and with peripheral venous injection of indocyanine green dye and an arterial cuvette, the measured points fell within the range of plus or minus 20% on both sides of the line of identity in 19 instances. Studied on 8 human subjects with radiocardiography and ear-dye method performed simultaneously with peripheral venous injection of a mixture of R131ISA and indocyanine green, cardiac output given by ear-dye method was higher than that given by radiocardiography by an average of 9 plus or minus 11 (SD)%. Agreement and disagreement in cardiac output measurements given by electromagnetic flow probe, dye-dilution method with arterial cuvette, dye-dilution method with ear-piece densitometer and radiocardiography were discussed.

Animals↗

Superior mesenteric blood flow in man studied with a dye-dilution technique.

The superior mesenteric blood flow in the post-absorptive state was studied with a dye-dilution technique using indocyanine green in 37 patients with apparently normal small bowel function. All the patients except 2 had been, or were to be, treated because of malignant disease, mostly rectal carcinoma. The investigations were performed in connection with portography. The dye was injected into the superior mesenteric artery as a single injection during continuous sampling of blood from the superior mesenteric vein, catheterized through the reopened umbilical vein. The blood flow was calculated from the dye-dilution curves obtained with a modified Stewart-Hamilton formula. As recirculating dye appeared in the later part of the dye-dilution curves, the appearance of the recirculating dye was timed in 4 patients. The hepatic extraction of the amount of dye usually injected, 1.25 mg, was 60%. The superior mesenteric blood flow averaged 706 ml/min (397 ml/min/m-2 body surface) or 12% of the cardiac output. The appearance time, mean transit time, vascular resistance and vascular volume were also determined.

Adolescent↗

Standardized measurement of amniotic fluid volume by correlation of sonography with dye dilution technique.

Amniotic fluid volume was measured in two ways in 23 subjects admitted for interruption of pregnancy at gestational ages 16-24 weeks. The amniotic fluid volume calculated from sonographic measurements was plotted against the "true" amniotic fluid volume obtained by a dye dilution technique. Linear regression analysis showed a good correlation between the two methods (r = 0.815; P less than .001) and yielded a factor that may be used on a general basis to derive the true amniotic fluid volume from the value obtained by sonography. This approach thus offers a standardized procedure for amniotic fluid volume estimation in the second trimester based on the technical simplicity of ultrasonography with the relative accuracy of the dye dilution technique.

Adolescent↗

Repeated plasma volume determination with the Evans Blue dye dilution technique: the method and a computer program.

This paper describes a reliable multiple sample Evans Blue dye dilution technique and a Pascal program which computes plasma and blood volume on the basis of this technique. The program performs needed corrections and dye disappearance curve fitting. It provides menu-driven facilities for data correction, graphic display of the dye disappearance curve, and print-out of all the involved data. Means +/- S.E.M. for three plasma volume determinations in each of six resting subjects were: 3239 +/- 96 ml, 3189 +/- 81 ml, and 3187 +/- 102 ml. The differences were not statistically significant.

Blood Volume↗

A method for quantitative detection of tricuspid regurgitation with double injection--single sampling dye-dilution technique.

A method for quantitative detection of tricuspid regurgitation is proposed. In cases without tricuspid insufficiency or intracardiac shunt, 1/slope (ts-fv) of the earpiece dye-dilution curve after injection of dye into the femoreal vein (fv curve) was significantly correlated with that (ts-pa) of the curve after injection into the pulmonary artery (PA curve) within each range of right heart blood volume (rbv) calculated as a product of cardiac output and mean transit time difference between FV curve and PA curve. The relationship among the 3 parameters was expressed as a statistically significant regression equation; log (tsfv) equals 0.9858 log (ts-pa) plus 0.2980 log (RBV) minus 0.6418 (p small than 0.005, sd of predicted ts-fv equals plus or minus 0.591). The assumption was made that tricuspid regurgitation caused prolongation ot ts-fv without any changes in ts-pa or RBV, being based on the concepts of the indicator dispersion and of the path-length distribution. The ratio of tricuspid regurgitation to cardiac output was calculated from (observed ts-fv-predicted ts-fv)/predicted ts-fv, in which predicted ts-fv is the value calculated from ts-pa and RBV using the equation shown above. In 2 patients who manifested clinical tricuspid insufficiency, large amount of tricuspid regurgitant fraction was determined by this method. It is suggested that the present method utilizing double injections--single sampling dye-dilution technique is useful for clinical quantitation of tricuspid regurgitation.

Adolescent↗

Arteriovenous shunting in carcinomas evaluated by a dye dilution technique.

In 19 patients with renal carcinomas determination of the renal blood flow and related parameters were determined. In 10 of the kidneys the renal blood flow was higher than 1700 ml/min, in five kidneys the vascular volume was increased and in all kidneys the appearance time of dye in the renal vein was below normal. It is concluded that AV-shunting is present in all renal carcinomas even if they are hypovascularized or cystic. Underperfusion is supposed to be present in the normal renal parenchyma surrounding the carcinoma. The shunted amount of blood can be fairly large, in the present series up to 3 1/2 litre. The dye dilution technique is suitable for studies of the hemodynamics in renal carcinomas.

Arteriovenous Fistula↗

Effect of angiotensin on normal renal circulation determined by angiography and a dye dilution technique.

Angiotensin in a dose of 0.5 to 1.0 microgran injected into the renal artery of healthy kidneys initially decreased renal blood flow and increased the appearance time and mean transit time of dye and contrast medium as examined by a dye dilution technique and angiography. The initial phase is followed by a reactive hyperemia. The increased vascular resistance is probably localized peripherally on the arterial side of the vascular tree. Optimum dose is 0.5 to 1.0 microgram angiotensin in diagnosis of renal tumours. Optimum interval between drug administration and angiography is 10 to 60 s.

Angiotensin II↗