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[Ischemic cardiopathies in Africans in Djibouti. Study of 431 cases in 5 years].

Ischemic cardiopathies in Eastern Africans at Djibouti are frequent: 2.9 % of the in patients and 73 % of the cardiac diseases. Male prevalence is marked. Coronary insufficiency is most often demonstrated by the usual symptomatology. Three groups of electrocardiopathic manifestations have been individualised: ischemia proving angor (288 cases), anginose syndromes revealing a myocardic infarct (81 cases), acute myocardic infarcts (62 cases). The patients come for the most part from Djibouti and belong to any social class. The part played by a food mainly constituted of complex glucids, refined sugar and lipids is pointed out. Arterial hypertension, diabetes, essential hypercholesterolemia and tobacco intoxication are the most frequent risk factors. This coronary pathology is closer the one met with in the Near East than ischemic cardiopathies observed in tropical Africa which begin to emerge.

Adult

Molecular epidemiology of panton valentine leukocidin-producing Staphylococcus aureus infections, Djibouti, 2018-2023.

Between 2018 and 2023, a genomic study was conducted in a military camp in Djibouti to investigate the molecular epidemiology of Panton-Valentine Leukocidin-producing Staphylococcus aureus. Among 43 isolates, Sequence Type 152 was predominant (72%), mainly associated with spa types t355 and t4235. Core-genome Multi-Locus Sequence Typing revealed two concurrent transmission dynamics: localized inter-human outbreaks and repeated introductions from external sources. Comparative genomics with other African Sequence Type 152 isolates showed similar levels of diversity, suggesting a widespread continental dissemination. These findings highlight the importance of genomic surveillance to better understand and control the spread of this virulent lineage in Africa.

Leukocidins

[Reaginic allergy to mold in Djibouti].

16,7 P. 100 OF RESPIRATORY ALLERGIC DISEASES IN Djibouti are caused by years, as demonstrated by the utilization of M. and M2 compounds prepared by Institut Pasteur. The role of air-conditionners appears important. Cultures of dust collected from filters reveale a much greater number of positive yeast cultures than front air.

Adult

[The question of endemic malaria in Republic of Djibouti (author's transl)].

Since 1973 autochthonous cases of malaria due to P. Falciparum have been reported among local population of French Afars and Issas Territory; 191 cases observed between 1973 and 1976 are recorded. Their monthly distribution and geographical repartition are studied, jointly with the distribution of A. gambiae which has been recently collected in the Territory. This study shows a significant correspondance between the presence of A. gambiae and the malaria cases observed which did not come from neighbouring countries. We may, then, expect the development of small disseminated foci, resulting from the simultaneous introduction of both the parasite and its anopheline vector. This brings about a new epidemiological situation for the Territory.

Africa, Eastern

[Preliminary results of an entomological survey of the potential arbovirus vectors in the French Territory of Afars and Issas].

The preliminary results of an entomological survey of the potential arbovirus vectors in the French Territory of Afars and Issas are exposed. 25 culicid species were recorded, specially Anopheles gambiae, Culex tritaeniorhynchus, C. univittatus, C. pipiens fatigans, Aedes caspius, Ae. vittatus, Ae. arabiensis. Ae. aegypti larvae were collected on a dhow arriving in Djibouti. 5 species of ticks and 4 sandfly speices were also recorded. The epidemiological modalities of certain arboviroses in this territory are discussed, depending on these entomological data and the uniterrupted travelling of local populations.

Animals

[Peritoneal tuberculosis in Africa (author's transl)].

Peritonel tuberculosis is quite frequent overseas and specially in Africa; as an example, it is about 0,5 p. 100 of the admittances and 13 p. 100 of the total number of tuberculous cases recorded in Dakar and Djibouti, over a period of four years. First symptoms are not caracteristic but rapidly one may observe either ascitic or non-ascitic forms, with eventually pseudo-tumoral or adhesive aspect. Diagnostic criteria are reviewed as well as the therapeutic rules and results.

Adolescent