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At least 19 recordsLinked to original sources

[Study on feeding behavior patterns of rats on cariogenic diet].

The feeding behavior patterns of Jcl:Wistar rats fed on commercial stock diet and cariogenic diet (Diet #2000) were investigated with the newly developed autorecording system. They were caged separately under a regular light-dark cycle (L:D = 12:12). The results and conclusion were as follows. All rats have a circadian feeding rhythm, and 70-85% of feeding frequency were observed during the dark period. The group on the commercial stock diet showed a dual-peak pattern of feeding at 20:30 and 4:00. On the other hand, the cariogenic diet groups showed a more frequent feeding pattern during the dark period. The feeding frequency increased from 1:00 to 3:00 in the high sucrose diet group and more frequent feeding was observed. From these results, it was suggested that dental caries in the rats was caused by not only the local effect of sucrose in the mouth but also by the changing patterns of feeding behavior with cariogenic diet.

Animals↗

[Vitamin E and experimental caries in rats fed a cariogenic diet and zinc].

A cariogenic diet with zinc and vitamin E administered to rats for 90 days led to a reduction in caries of 21.87% by comparison with animals fed with the cariogenic diet only, and 3.12% by comparison with those that received the diet plus zinc. Although the details of the mechanism of action of vitamin E are not fully known, it is felt that its demonstrated cariostatic effect depends on its antioxidant activity and its protection of the sulphydryl groups of some enzyme system, together with its direct intervention in cell respiration. Since both vitamin E and zinc activate NAD-dependent LDH, their simultaneous administration enhances their individual cariostatic effects by bringing about a lower accumulation of lactic acid in the bacterial plaque.

Animals↗

[Structural modifications of secretory epithelial cells of the salivary glands induced by a carbohydrate-rich cariogenic diet in rats].

Rats receiving a carbohydrate rich cariogenic diet (Stephan 580) showed structural modifications of their salivary glands when compared to a control group. These observations suggested that a disturbance of the after birth organogenesis sequences occurred during the experimental period for the submandibular glands. The elaboration of elaboration of secretion granules was strongly decreased in the parotid acinar cells. Such an indirect action of the hyperglucidic diet could contribute to the carious process development by modifying the oral environment.

Animals↗

Effect of fluoride on caries progression and dentin apposition in rats fed on a cariogenic or non-cariogenic diet.

The effect of fluoride in drinking water on the progression of dentinal caries and dentin apposition was studied in Wistar rats. The initiation of enamel caries lesions was first induced for 2 wk with S. sobrinus and a 43% sucrose diet after weaning. Thereafter the animals were fed on either a cariogenic or a non-cariogenic diet and distilled water supplemented with 0, 1, 7 or 19 ppm fluoride. The areas of dentinal caries and dentin apposition were quantified after tetracycline staining. Fluoride reduced dentinal caries progression after the initiation of lesions in the presence of a cariogenic diet at a concentration of 19 ppm F, and without sucrose at 1 ppm F. The effect of fluoride in reducing dentin apposition with a cariogenic diet was dose-dependent, whereas fluoride in non-cariogenic groups had practically no effect on dentin formation. These results suggest that fluoride together with a high concentration of sucrose in the diet might have an odontoblast-mediated effect on the regulation of the progression of dentinal caries.

Analysis of Variance↗

Relationship between cariogenic diet and dental caries as evaluated from a 5-day diet diary in 4-12 year-old children.

A preliminary study was conducted on 50 children in the age group of 4-12 years, who were divided into two groups on the basis of decayed, missing and filled teeth (DMFT) i.e. Group A (1-3) and Group B (> 3). A 5-day diet diary was evaluated and Sweet Score, Total Sugar Exposure, At Meal Sugar Exposures and Between Meal Sugar Exposure were calculated. There was statistically significant difference between the two groups in relation to Sweet Score and Total sugar Exposures. Between Meal Sugar Exposure and At Meal sugar exposure did not differ significantly.

Child↗