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Metronidazole was investigated in the basic dermatologic agent Elacutan W to improve the topical therapy of rosacea. The suitability of that basic dermatologic agent was verified for metronidazole, prednisolone and dexamethasone by stability tests (UV-spectroscopy, pH) and by in-vitro-liberation-measurements (membrane method). The drugs are stable for a period of 100 days.
Individual protective dermatologic agents are an indispensable component of the complex of prophylactic measures for occupational dermatologic diseases control. The last decade has seen a variety of new protective agents: industrial allergen inactivators, effective surfactants, and universal creams. Plamin, a universal cream manufactured in Sweden, is characterized by the optimal protective properties and is resistant to many aggressive media.
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