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Results for “DENTIN SENSITIVITY”

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At least 19 recordsLinked to original sources
PubMed1991

An in vivo study of dentin sensitivity: the relation of dentin sensitivity and the patency of dentin tubules.

Dentin hypersensitivity can be a major problem for periodontal patients. The relationship between dentin hypersensitivity and the patency of dentin tubules in vivo has been established. Thirteen adult patients with teeth scheduled for extraction were selected and a stent fabricated to confirm location of the root surface being examined. Response to a constant air blast was recorded on a numeric pain rating scale (from 0 to 4) during the course of treatment. The tooth surface was initially treated with 0.5 molar EDTA (pH = 7.4), to remove the smear layer and expose tubules. The region was then treated with either a 3% monopotassium-monohydrogen oxalate solution or a 3% sodium chloride solution, both at pH = 2.4. Solutions were prepared to be indistinguishable to the examiner. Response to air was evaluated before and after EDTA treatment and after treatment with a desensitizing agent. The patient was anesthetized and the treated tooth extracted. Specimens were sectioned, critical point dried, sputter coated with gold, and examined under the scanning electron microscope. Photomicrographs were analyzed by computer assisted digital analysis to evaluate the degree of tubule occlusion. Statistical analysis by repeated measures ANOVA for univariate tests of hypothesis for within subject effects showed the sodium chloride solution was more effective in reducing dentin sensitivity than the potassium oxalate solution. Scanning electron micrographic analysis revealed a mean dentin tubule aperture size of 1.720 square microns following EDTA treatment alone, 0.564 square micron following potassium oxalate treatment, and 0.386 square micron following sodium chloride treatment.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1999

Clinical evaluation of the effect of a remineralizing toothpaste on dentinal sensitivity.

Dentinal hypersensitivity is a common dental problem without a satisfactory solution. Most therapies have focused on either trying to block the stimulation of dentinal nerves or on sealing open dentinal tubules. This study evaluated, in a double blind clinical trial, the effect of Enamelon, a dentifrice containing sodium fluoride, calcium salts and phosphate salts (calcium separated from the phosphate and fluoride by a plastic divider in the tube to prevent interaction) on dentinal hypersensitivity over an 8-week period. A conventional OTC dentifrice containing NaF without calcium and phosphate enhancement served as the control. A third dentifrice, containing sodium monofluorophosphate enhanced by calcium and phosphate salts, was also tested. Based upon subjective anecdotal information, net numbers of sensitive teeth which became non-sensitive, and a logit analysis of the change in the proportion of sensitive teeth over the study time period, Enamelon was the most effective product, and the OTC control the least effective.

Analysis of Variance↗
PubMed1984

Clinical evaluation of the effectiveness of three dentifrices in relieving dentin sensitivity.

It has been reported that sensitive dentin is present in no less than one of seven normal patients with a higher incidence among postperiodontal therapy patients. Numerous agents have been developed to relieve this sensitivity without any being universally acceptable. Two new dentifrices, Protect and Protect with fluoride were compared clinically with Sensodyne to determine the relative ability of these three products to relieve both thermal and tactile sensitivity in sensitive dentin. Double blind analyses were completed and results compared using appropriate statistical tests for each hypothesis tested. The three dentifrices relieved both tactile and thermal sensitivity, but there was no statistical difference at 8 weeks between the three agents. There was a difference in the time it took the dentifrices to achieve a statistically significant reduction in dentin sensitivity.

Adult↗
PubMed2000

Intraoral fluoride releasing device: a new clinical therapy for dentine sensitivity.

BACKGROUND: Dentinal sensitivity (DS) occurs frequently in adult populations in western countries. The purpose of this work was to assess the effectiveness of a new intraoral fluoride releasing device (IFRD) in reducing the level of pain in patients with primary or postsurgical dentine sensitivity. METHODS: A total of 49 individuals were selected for this study, 15 of whom had post-periodontal surgery dentine sensitivity and 34 with primary sensitivity. An IFRD was applied to 39, while 10 received a placebo device. All individuals in the control group suffered from primary sensitivity. The IFRD used in this study consists of sodium fluoride encased in an acrylic polymer which releases fluoride at a rate of approximately 0.04 mg/day. All patients were asked to rinse with cold water (10 degrees C) and to indicate the level of pain on a 0 to 10 visual analog scale, 0 equalling "no pain" and 10 "maximum bearable pain." All subjects were evaluated once a week during 4 months. Statistical analysis of dentine sensitivity was performed as a univariate study, in relation to the main factors: age, gender, and primary sensitivity or postsurgical etiology. RESULTS: Symptoms decreased dramatically in all treated patients. The level of sensitivity did not change during the first week after IFRD application, but decreased significantly within the fourth week and remained absent through the duration of the treatment (P <0.01). Difference in sensitivity with respect to different etiology was significant only after 4 weeks (P= 0.01), while there was no statistical difference with respect to age or gender. CONCLUSIONS: This paper is an initial study to evaluate the effectiveness of the IFRD. The method is fast, painless, inexpensive, and it appears to be suitable as a routine treatment. The presented data support the conclusions at this stage and warrant more comprehensive evaluation.

Administration, Topical↗
PubMed1994

Dentine permeability and its role in the pathobiology of dentine sensitivity.

The classical hydrodynamic theory implicated fluid movement as a transducing mechanism in the production of dental sensitivity. This theory assumes that sensitive dentine must be permeable. Various measurements of dentine permeability are discussed, including: (1) factors that influence diffusive permeation across dentine; (2) factors that influence convective fluid movement across dentine; (3) osmotic activities of solutions; (4) comparison of evaporative and convective fluid movement; (5) the interaction between outward convective fluid flux on the inward diffusive flux of molecules; and (6) the importance of pulpal blood flow in the clearance of noxious substances from dentine and pulp, a balance concept. The variables involved in achieving good penetration of desensitizing agents in the presence of outward movement of dentinal fluid are also discussed, along with the presentation of a new hypothesis which emphasizes the importance of dentine as a dynamic physiological barrier that works in harmony with neurovascular elements in the pulp in an attempt to maintain the health of the pulp-dentine complex.

Animals↗
PubMed1997

The Dentin Disc surface: a plausible model for dentin physiology and dentin sensitivity evaluation.

Dentin sensitivity (DS) is a painful clinical condition which may affect 8-35% of the population. Various treatment modalities have claimed success in relieving DS, although at present there does not appear to be a universally accepted desensitizing agent. Current opinion based on Brännström's Hydrodynamic Theory would suggest that following exposure of the dentin surface (through attrition, abrasion, or erosion), the presence of open dentinal tubules, patent to the pulp, may be a prerequisite for DS. The concept of tubule occlusion as a method of dentin desensitization, therefore, is a logical conclusion from the hydrodynamic theory. The fact that many of the agents used clinically to desensitize dentin are also effective in reducing dentin permeability tends to support the hydrodynamic theory. This paper reviews the in vitro evaluation of desensitizing agents, the techniques used to characterize their effects on the prepared dentin surface, and the ability of these agents to reduce permeability through tubule occlusion, and presents recent findings from ongoing research based on the Pashley Dentin Disc model. It can be concluded that the use of this model to determine surface characteristics, and reductions in dentin permeability through tubule narrowing or occlusion, provides a useful screening method for evaluating potential desensitizing agents. Interpreting changes observed in vitro is difficult, and extrapolation to the clinical situation must be tempered with caution.

Animals↗
PubMed1997

Aetiology, prevalence and clinical features of cervical dentine sensitivity.

Cervical dentine sensitivity (CDS) is a painful response to thermal, physical or chemical stimulation of the cervical area of the tooth. The reported prevalence of this clinical condition ranges from 8 to 35% depending on the population studied and methodology used to evaluate CDS. Detailed epidemiology is lacking with regard to possible causal factors. Well conducted studies in larger populations using accepted standardized methodology for both questionnaire and clinical examination are essential if these factors are to be identified and the condition successfully prevented and treated. This paper reviews current literature on the prevalence, aetiology and oral distribution of this troublesome condition.

Dentin Sensitivity↗
PubMed1992

Dentin permeability and dentin sensitivity.

The hydrodynamic theory of dentin sensitivity is based on the premise that sensitive dentin is permeable throughout the length of the tubules. Such a condition may permit the diffusion of bacterial products across dentin to the pulp where they may cause irritation of pulpal soft tissues. However, the slow outward movement of dentinal fluid tends to flush the tubules free of exogenous substances. This balance between the inward diffusion of exogenous substances, whether bacterial or the active ingredients in desensitizing medicaments, and the cleansing action of dentinal fluid flow needs to be examined experimentally.

Dentin↗
PubMed1997

Clinical evaluation of cervical dentine sensitivity in a population of patients referred to a specialist periodontology department: a pilot study.

The prevalence of tooth sensitivity [Cervical Dentine Sensitivity (CDS)] in adult populations indicates that 8-35% of subjects reported CDS depending on the population studied and the methodology used. Few studies, however, have reported on the prevalence of CDS in periodontal patients. The aim of the study was to determine the prevalence, severity and distribution of CDS in patients referred for specialist periodontal diagnosis. Fifty-one patients [27 male, 24 female; mean age 48.5 years (standard deviation 11.63)] who gave their informed written consent were clinically evaluated for CDS using recognized methods of assessment, namely Yeaple probe, cold air blast and subjective evaluation. Other clinical variables (e.g. plaque and recession scores) were also recorded at this visit. Regression analysis and correlation coefficients were used to determine the relationship between the clinical variables. The results demonstrated a prevalence of CDS ranging between 72.5 and 98% of patients, with no significant gender difference. Results for the distribution of tooth types showed that molar teeth were mainly affected, followed by left canines and premolars. No correlation was noted between plaque, recession, response to tactile or thermal stimulation. Pain response from tactile and thermal stimulation showed no significant difference between tooth surfaces. Cold stimulation was perceived to be the dominant pain-producing stimulus as had been previously reported. The results of this investigation support those from another study, which found the prevalence of CDS to be higher in periodontal patients than has been reported elsewhere. This finding would suggest that previous periodontal treatment and/or periodontal disease may play a role in the aetiology of CDS.

Adolescent↗
PubMed1990

Mechanisms of dentin sensitivity.

This article reviews dentin sensitivity from a mechanistic perspective beginning with short treatments of pulpal innervation, the hydrodynamic considerations of dentin, and how various stimuli may cause pain. Speculation is raised about the contribution of bacteria and their products on dentin sensitivity and how dentin might become truly hypersensitive, especially following periodontal therapy. Wherever possible, the clinical considerations of basic research is stressed.

Dental Pulp↗
PubMed1996

The effectiveness of desensitizing agents for the treatment of cervical dentine sensitivity (CDS)--a review.

The treatment of dentine sensitivity or cervical dentine sensitivity (CDS) has been in the form of dentifrices, mouth rinses, sealants, and other therapeutic techniques. Claims of efficacy of the "so-called" active ingredients of these desensitizing agents have been made on the basis of the proposed mode of action generally extrapolated from in vitro or animal studies. Evidence from published, well-controlled clinical studies, however, generally has failed to substantiate such claims, although there has been a reported significant reduction in discomfort by subjects participating in these studies. Currently, the most accepted mechanism of intradental nerve activity associated with dentine sensitivity appears to be hydrodynamic in nature, although other mechanisms cannot be eliminated. The concept of tubule occlusion as a method of dentine desensitization is a logical conclusion from the hydrodynamic hypothesis. This paper reviews the present position with regard to the treatment of dentine sensitivity by various desensitizing agents and evaluates their claims of efficacy in the context of available scientific evidence.

Animals↗
PubMed1994

Dental pain evoked by hydrostatic pressures applied to exposed dentin in man: a test of the hydrodynamic theory of dentin sensitivity.

The hydrodynamic theory of dentin sensitivity holds that pain is evoked by stimuli producing minute shifts in tubule fluid. In human volunteers hydrostatic pressures were applied to prepared dentinal cavities. The subjects reported the magnitude and quality of their sensations of pain by means of an intermodal matching technique in combination with verbal descriptors. No pain could be elicited when the smear layer was present. After removal of this layer, pressure stimuli of either direction evoked sharp pain. Rapid changes in pressure induced higher pain intensities than slow changes, indicating that the dental A-delta system is dynamic and gradient dependent. These results provide support for the hydrodynamic theory of dentin sensitivity and also lend credence to the notion that the movement of fluid across dentin induces a selective activation of the A-delta nerves in healthy pulps which is highly correlated with a sensation of sharp and/or shooting pain.

Acid Etching, Dental↗
PubMed2002

The effects of a novel Bioglass dentifrice on dentine sensitivity: a scanning electron microscopy investigation.

Dentine sensitivity (DS) is a common condition which affects 8-35% of the population. Both In-Office and Over-the-Counter products have been used in treatment, usually occluding open dentine tubules on the exposed root surface. Currently there appears to be no ideal material which permanently occludes dentine tubules. Bioactive and biocompatible glasses are known to induce osteogenesis in physiological systems and may offer suitable materials for surface reactivity which could theoretically occlude tubules. A new dentifrice formulation containing a modified Bioglass material replacing part of the abrasive silica component was compared with original 45S6 bioactive glass. Dentine discs were treated with original Bioglass, three coded dentifrices containing 0, 2.5 and 7.5% Bioglass and two further selected dentifrice products. These specimens were prepared for scanning electron microscopy (SEM) and viewed in a Cambridge stereoscan 90B. The results demonstrated that original bioactive glass particles covered the dentine surface and/or occluded dentine tubules, although this original formulation was easily dislodged. Dentifrice with different ratios of added Bioglass was assessed to provide greater surface coverage and tubule occlusion than without Bioglass. It was concluded that the inclusion of bioactive glass particles in a suitably formulated vehicle may be an effective agent for the treatment of dentine sensitivity.

Biocompatible Materials↗
PubMed1994

Morphological features of dentine and pulp related to dentine sensitivity.

This review considers those structural features of the pulp and dentine relevant to an understanding of dentine sensitivity. It does not discuss innervation, or microvasculature, which are covered in other contributions. The sensitivity of dentine is directly related to the size and patency of the dentinal tubules. Tubular occlusion by peritubular dentine deposition or the formation of other intratubular material would reduce the flow of fluid and diffusion of molecules through dentine. Irregular (reparative) secondary dentine would, because its tubules are not continuous with those of primary dentine, be expected to reduce permeability and fluid flow and decrease sensitivity. Regular secondary dentine would have little or no effect other than by increasing diffusion distances. The odontoblast layer is of limited permeability and could restrict the access of materials diffusing through the dentinal tubules to pulpal axons. Odontoblasts are not involved in the sensory process as special sensory receptors but may, by modifying the local ionic environment, alter the threshold of intradentinal nerves.

Animals↗
PubMed1990

The influence of frequent ingestion of acids in the diet on treatment for dentin sensitivity.

For many patients with severe and persistent pain from dentin sensitivity, therapeutic interventions often produce unsatisfactory results. Eighteen patients with persistent dentin sensitivity following a two-month clinical trial of a desensitizing dentifrice and a two-week treatment of four applications of a topical fluoride varnish participated in post-hoc evaluation of the association between the frequency of acid ingestions in the diet and the persistence of pain. A specific food frequency assessment was performed and tested for association against longitudinal, clinical and subjective patient assessments. There was a negative association (r = 0.49) between the frequency of ingestion of specific acid foods and beverages and the persistence of dentin sensitivity. Findings suggest that nutritional counselling should be part of the treatment offered for patients with these problems.

Acids↗
PubMed2006

Comparison of two topical treatments for dentine sensitivity.

This study compares two commercially-available products for treating dentine sensitivity, Duraphat, a fluoride varnish, and SuperSeal, an oxalate preparation. 48 patients with dentine sensitivity were recruited. Sensitivity was assessed by visual analogue scales (VAS) to record pain following stimulation of exposed dentine surfaces by tactile stimulus (sharp probe at 60g force), thermal stimulus (ethyl chloride) and evaporative stimulus (air drying). Patients were randomised to treatment with either Duraphat or SuperSeal. After 4 weeks, sensitivity assessments were repeated. Both treatments resulted in statistically significant reductions in VAS scores for all stimuli (P<0.05). However, analysis of covariance failed to identify statistically significant differences in the magnitude of reductions in sensitivity achieved by each of the products (P>0.05). The treatments had similar efficacy and both can be considered effective therapies for treating dentine sensitivity.

Adult↗