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Results for “DDT/related compounds”

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At least 19 recordsLinked to original sources
PubMed1961

Uterotrophic action of the insecticide methoxychlor.

Dusting of rats and mice, as well as oral treatment with the insecticide methoxychlor, produced uterine weight increase in these rodents. Ablation of the ovaries, adrenals, or pituitary did not alter this effect, thus indicating a direct trophic action of this agent on the uterus. It is apparent that the application of this insecticide to animals used for hormonal experiments introduces an additional variable.

Animals↗
PubMed1962

Action of 1,1,dichloro-2-p-chlorophenyl-2-o-chlorophenylethane on dog adrenal cortex.

A single intravenous injection of op'DDD (1,1,dichloro-2-p-chlorophenyl-2-o-chlorophenylethane) has an acute effect on the adrenal cortex of the dog. Within 2 hours after intravenous injection of the drug, there is a decrease in the in vitro response of the adrenal cortex to stimulation by adrenocorticotrophic hormone and an inhibition of glucose-6-phosphate dehydrogenase activity. The inhibition of glucose-6-phosphate dehydrogenase activity might explain the effect of op'DDD on corticosteroid production.

Adrenal Cortex↗