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At least 19 recordsLinked to original sources

A computer method for the acquisition and analysis of patch-clamp single-channel currents.

The method we present instructs the computer to deliver sets of programmed membrane voltages and allows the acquisition of large amounts of digitized data, compact storage, ready identification of records and rapid, interactive analysis of channel current data. A typical cycle of analysis including amplitude determination and kinetic measurements for 10 s of continuous data digitized at 5 kHz requires 5-20 min depending on the complexity of the observed channel activity. This procedure is compatible with such storage protocols as that described by Bezanilla [Biophys. J., 47 (1985) 437-441], although there are obvious benefits to using standard computer storage devices such as hard disks, floppy disks, and Bernoulli Boxes. The programs described in this report are available from the authors.

Animals

Literature databases for radiologists.

There are two new computerized radiology literature databases available for those practitioners who require a more sophisticated retrieval system than the Index to Imaging Literature published annually by Radiology. The installation and use of these two products, the floppy disk based PC MASS and the CD-ROM based SilverPlatter Radiology are discussed. The advantages and disadvantages of both desktop programs are compared with the Index and to the telecommunication access of large general medical databases such as MEDLINE.

CD-ROM

The impact of image storage organization on the effectiveness of PACS.

Picture archiving communication system (PACS) requires efficient handling of large amounts of data. Mass storage systems are cost effective but slow, while very fast systems, like frame buffers and parallel transfer disks, are expensive. The image traffic can be divided into inbound traffic generated by diagnostic modalities and outbound traffic into workstations. At the contact points with medical professionals, the responses must be fast. Archiving, on the other hand, can employ slower but less expensive storage systems, provided that the primary activities are not impeded. This article illustrates a segmentation architecture meeting these requirements based on a clearly defined PACS concept.

Computer Storage Devices

Image archival technologies.

A typical radiology department can create many gigabytes of image data per day and as much as 1 terabyte of data per year. Archiving and accessing this much data are substantial problems. One solution is data compression, which decreases data storage requirements and increases the rate of data transfer; however, standards are not yet available. Other solutions involve improvements in archival media. Jukebox subsystems allow automated access to multiple units. Digital magnetic tape, the standard medium, can store large amounts of information and enables easy updates or replacements; more practical technologies have been introduced in recent years. Digital videotape allows storage of digital video data and features a high rate of data transfer. Optical disks, now the preferred permanent archival medium, have a large storage capacity and provide excellent long-term stability. Optical tape is also being investigated as a solution to the archiving dilemma. Which technology to choose depends on many factors, including needs of the institution and the cost, stability, transfer time, and storage capacity of the system.

Computer Storage Devices

The development of a virtual database to provide on-line access to a large archive of clinical data.

The archival database of the HELP Hospital Information System at LDS Hospital is too large to be stored on line. The archival data are important for clinical and research applications. Demountable disk packs have been used to store the archival database. This method of storage has four significant disadvantages. A virtual database was developed to overcome the limitations of this data-management scheme. This virtual database enables the transparent use of appropriate low-cost network-based storage technology to provide on-line availability of the entire archive of clinical data. The virtual database successfully resolves the problems associated with disk packs, and opens the door to enhanced use of the data for clinical and research applications.

Computer Storage Devices

Influences on the performance of hospital clinical event monitoring.

The implementation of real-time clinical monitors in large hospital information systems places large performance demands on these systems. Meeting these demands not only requires methodologies to augment the performance of individual monitors but an understanding of how patient population and monitor characteristics might influence overall system performance. We have built a multimonitor simulator to study these influences on performance. In doing so, we have focused on the impact of a variety of techniques to cache a subset of a large number of monitors in primary memory.

Boston

Smart Pharmacy Cards to automate patient records for prospective drug utilization review.

The Smart Pharmacy Card automates the patient's medical and prescription history so that every new prescription can be analyzed by a pharmacist to determine if it conflicts with disease states, allergies, prescription and non-prescription drugs documented in the card. The prototype that will be demonstrated at SCAMC 1991 will use an integrated-circuit card ("smart card") that holds 16,000 bits of electronically-erasable data.

Clinical Pharmacy Information Systems